BRPI0908008A2 - Farmacóforo dual - pde4-antagonistas muscarínicos - Google Patents

Farmacóforo dual - pde4-antagonistas muscarínicos

Info

Publication number: BRPI0908008A2
Authority: BR; Brazil
Prior art keywords: pde4; muscarinic antagonists; dual pharmacophore; pharmacophore; dual
Prior art date: 2008-02-06

Application number

BRPI0908008-2A

Other languages

English (en)

Inventor

James Francis Callahan

Guoliang Lin

Zehong Wan

Hongxing Yan

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-02-06

Filing date

2009-02-05

Publication date

2015-08-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40935342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0908008(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-02-05 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2015-08-18 Publication of BRPI0908008A2 publication Critical patent/BRPI0908008A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Immunology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0908008-2A 2008-02-06 2009-02-05 Farmacóforo dual - pde4-antagonistas muscarínicos BRPI0908008A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2656308P	2008-02-06	2008-02-06
PCT/US2009/033128 WO2009100166A1 (en)	2008-02-06	2009-02-05	Dual pharmacophores-pde4-muscarinic antagonistics

Publications (1)

Publication Number	Publication Date
BRPI0908008A2 true BRPI0908008A2 (pt)	2015-08-18

Family

ID=40935342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0908008-2A BRPI0908008A2 (pt)	2008-02-06	2009-02-05	Farmacóforo dual - pde4-antagonistas muscarínicos

Country Status (19)

Country	Link
US (1)	US8084449B2 (pt)
EP (1)	EP2259681A4 (pt)
JP (1)	JP2011511082A (pt)
KR (1)	KR20100113155A (pt)
CN (1)	CN101990401A (pt)
AR (1)	AR070562A1 (pt)
AU (1)	AU2009212408A1 (pt)
BR (1)	BRPI0908008A2 (pt)
CA (1)	CA2714352A1 (pt)
CL (1)	CL2009000250A1 (pt)
CR (1)	CR11665A (pt)
DO (1)	DOP2010000235A (pt)
EA (1)	EA201070916A1 (pt)
IL (1)	IL207352A0 (pt)
MX (1)	MX2010008690A (pt)
PE (1)	PE20091552A1 (pt)
TW (1)	TW201000476A (pt)
UY (1)	UY31637A1 (pt)
WO (1)	WO2009100166A1 (pt)

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MX2012011784A (es)	2010-04-16	2013-03-21	Bayer Ip Gmbh	Nuevos compuestos heterociclicos como pesticidas.
US8367829B2 (en)	2010-05-10	2013-02-05	Gilead Sciences, Inc.	Bi-functional pyrazolopyridine compounds
RU2013103422A (ru)	2010-06-28	2014-08-10	Байер Интеллектчуал Проперти Гмбх	Гетероарил-замещенные пиридиновые соединения для применения в качестве пестицидов
US9763924B2 (en)	2014-06-05	2017-09-19	Chiesi Farmaceutici S.P.A.	Aminoester derivatives
CA2967332C (en)	2014-11-11	2024-05-21	Johnson & Johnson Consumer Inc.	Amino acid derivatives and their uses
US9321744B1 (en)	2015-06-26	2016-04-26	Industrial Technology Research Institute	Method for preparing 2,5-furan dicarboxylic acid
WO2017089347A1 (en)	2015-11-25	2017-06-01	Inserm (Institut National De La Sante Et De La Recherche Medicale)	Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas

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PE20050327A1 (es)	2003-07-17	2005-06-08	Glaxo Group Ltd	Derivados de 8-azoniabiciclo[3.2.1]octano como antagonistas de los receptores muscarinicos de la acetilcolina
PE20050250A1 (es)	2003-07-17	2005-04-08	Glaxo Group Ltd	Antagonistas de los receptores muscarinicos de la acetilcolina
MXPA06004244A (es)	2003-10-14	2006-06-28	Glaxo Group Ltd	Antagonistas del receptor muscarinico de la acetilcolina.
JP2007509061A (ja)	2003-10-17	2007-04-12	グラクソ　グループ　リミテッド	ムスカリン性アセチルコリン受容体アンタゴニスト
AR046225A1 (es)	2003-11-04	2005-11-30	Glaxo Group Ltd	Compuesto de 8-azoniabiciclo(3.2.1)octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos que lo comprende y uso del compuesto para preparar dicha composicion
UY28646A1 (es)	2003-12-03	2005-06-30	Glaxo Group Ltd	Nuevos antagonistas del receptor muscarinico m3 de acetilcolina
UY28645A1 (es)	2003-12-03	2005-06-30	Glaxo Group Ltd	Nuevos antagonistas del receptor muscarinico m3 de acetilcolina
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JP2007528420A (ja)	2004-03-11	2007-10-11	グラクソ　グループ　リミテッド	新規ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
AU2005223351A1 (en)	2004-03-16	2005-09-29	Glaxo Group Limited	Pyrazolo[3,4-b]pyridine compound, and its use as a PDE4 inhibitor
GB0405933D0 (en)	2004-03-16	2004-04-21	Glaxo Group Ltd	Compounds
GB0405937D0 (en) *	2004-03-16	2004-04-21	Glaxo Group Ltd	Compounds
EP1725564A4 (en)	2004-03-17	2007-09-12	Glaxo Group Ltd	ANTAGONISTS OF THE M3 MUSCARIN ACETYL CHOLIN RECEPTOR
US20070185148A1 (en)	2004-03-17	2007-08-09	Glaxo Group Limited	M3 muscarinic acetylchoine receptor antagonists
WO2005094834A1 (en)	2004-03-17	2005-10-13	Glaxo Group Limited	Muscarinic acetylcholine receptor antagonists
JP2007529514A (ja)	2004-03-17	2007-10-25	グラクソ　グループ　リミテッド	Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
EP1732923A2 (en)	2004-04-07	2006-12-20	Glaxo Group Limited	Muscarinic acetylcholine receptor antagonists
AR050902A1 (es)	2004-04-27	2006-12-06	Glaxo Group Ltd	Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion
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2009
- 2009-02-04 UY UY31637A patent/UY31637A1/es not_active Application Discontinuation
- 2009-02-04 AR ARP090100367A patent/AR070562A1/es not_active Application Discontinuation
- 2009-02-04 PE PE2009000167A patent/PE20091552A1/es not_active Application Discontinuation
- 2009-02-04 TW TW098103478A patent/TW201000476A/zh unknown
- 2009-02-04 CL CL2009000250A patent/CL2009000250A1/es unknown
- 2009-02-05 US US12/365,930 patent/US8084449B2/en not_active Expired - Fee Related
- 2009-02-05 BR BRPI0908008-2A patent/BRPI0908008A2/pt not_active IP Right Cessation
- 2009-02-05 AU AU2009212408A patent/AU2009212408A1/en not_active Abandoned
- 2009-02-05 WO PCT/US2009/033128 patent/WO2009100166A1/en not_active Ceased
- 2009-02-05 EP EP09708282A patent/EP2259681A4/en not_active Withdrawn
- 2009-02-05 KR KR1020107019677A patent/KR20100113155A/ko not_active Withdrawn
- 2009-02-05 MX MX2010008690A patent/MX2010008690A/es not_active Application Discontinuation
- 2009-02-05 EA EA201070916A patent/EA201070916A1/ru unknown
- 2009-02-05 CN CN2009801123576A patent/CN101990401A/zh active Pending
- 2009-02-05 CA CA2714352A patent/CA2714352A1/en not_active Abandoned
- 2009-02-05 JP JP2010545972A patent/JP2011511082A/ja active Pending
2010
- 2010-07-30 DO DO2010000235A patent/DOP2010000235A/es unknown
- 2010-08-02 IL IL207352A patent/IL207352A0/en unknown
- 2010-09-01 CR CR11665A patent/CR11665A/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
CL2009000250A1 (es)	2009-09-11
EA201070916A1 (ru)	2011-02-28
US20090203657A1 (en)	2009-08-13
CN101990401A (zh)	2011-03-23
AU2009212408A1 (en)	2009-08-13
UY31637A1 (es)	2009-08-03
CR11665A (es)	2011-01-11
EP2259681A1 (en)	2010-12-15
JP2011511082A (ja)	2011-04-07
DOP2010000235A (es)	2011-01-15
WO2009100166A1 (en)	2009-08-13
MX2010008690A (es)	2010-08-30
AR070562A1 (es)	2010-04-21
TW201000476A (en)	2010-01-01
IL207352A0 (en)	2010-12-30
PE20091552A1 (es)	2009-10-25
EP2259681A4 (en)	2012-04-04
CA2714352A1 (en)	2009-08-13
US8084449B2 (en)	2011-12-27
KR20100113155A (ko)	2010-10-20

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DE602009000234D1 (de)	2010-11-11	msignals
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DK3444343T3 (da)	2021-01-18	Polypeptider
PT3045471T (pt)	2017-06-14	Resumo
BRPI0914649A2 (pt)	2015-07-07	Piprazolo-quinazolinas
DE602008003972D1 (de)	2011-01-27	Sitzrücklehnungsmechanismus
DE602008003521D1 (de)	2010-12-30	Sitzrücklehnungsmechanismus
DK2342454T3 (da)	2013-10-28	Vindkraftanlæg
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DK2336132T3 (da)	2014-04-07	Morpholinpurinderivat
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DE602008003970D1 (de)	2011-01-27	Strahlstromkalibriersystem
EP2257170A4 (en)	2011-08-03	TETRAHYDROFUROPYRIDONE
EP2248964A4 (en)	2011-08-31	DRILLING / TERMINAL DEVICE
BRPI0907522A2 (pt)	2019-09-24	biarlamidas
DE112009000183A5 (de)	2011-02-03	Sicherheitsvorreiber
EP2280264A4 (en)	2016-04-20	STANDARD AGENTS
BRPI0909634A2 (pt)	2015-09-22	2-aminoquinolinas
DE602009000862D1 (de)	2011-04-28	Gehwagenbremse
EP2245356A4 (en)	2012-10-24	STRUCTURAL FIBER STRING, IMPREGNATED WITH RESIN

Legal Events

Date	Code	Title	Description
2015-12-08	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.