BRPI0819526A2 - "fragmento de ácido nucléico isolado, construção recombinante, célula de planta e método para reduzir a expressão de uma sequência alvo" - Google Patents
"fragmento de ácido nucléico isolado, construção recombinante, célula de planta e método para reduzir a expressão de uma sequência alvo"Info
- Publication number
- BRPI0819526A2 BRPI0819526A2 BRPI0819526-9A2A BRPI0819526A BRPI0819526A2 BR PI0819526 A2 BRPI0819526 A2 BR PI0819526A2 BR PI0819526 A BRPI0819526 A BR PI0819526A BR PI0819526 A2 BRPI0819526 A2 BR PI0819526A2
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- target sequence
- plant cell
- acid fragment
- reducing expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1451207P | 2007-12-18 | 2007-12-18 | |
| US61/014,512 | 2007-12-18 | ||
| PCT/US2008/087082 WO2009079532A2 (en) | 2007-12-18 | 2008-12-17 | Down-regulation of gene expression using artificial micrornas |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0819526A2 true BRPI0819526A2 (pt) | 2015-03-10 |
| BRPI0819526B1 BRPI0819526B1 (pt) | 2018-03-06 |
| BRPI0819526B8 BRPI0819526B8 (pt) | 2022-12-06 |
Family
ID=40427383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0819526A BRPI0819526B8 (pt) | 2007-12-18 | 2008-12-17 | Sequência de ácido nucleico de precursor de mirna artificial, construção recombinante e método para reduzir a expressão de uma sequência alvo |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8937217B2 (pt) |
| EP (4) | EP2261363B1 (pt) |
| BR (1) | BRPI0819526B8 (pt) |
| CA (3) | CA2709404C (pt) |
| ES (2) | ES2388489T3 (pt) |
| PL (1) | PL2261363T3 (pt) |
| WO (1) | WO2009079532A2 (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8937217B2 (en) | 2007-12-18 | 2015-01-20 | E. I. Du Pont De Nemours And Company | Down-regulation of gene expression using artificial microRNAs |
| WO2011109618A2 (en) | 2010-03-03 | 2011-09-09 | E. I. Du Pont De Nemours And Company | Plant seeds with altered storage compound levels, related constructs and methods involving genes encoding oxidoreductase motif polypeptides |
| MX2012012211A (es) | 2010-04-23 | 2012-12-17 | Du Pont | Composiciones de interruptores genicos y metodos de uso de las mismas. |
| US9062317B2 (en) * | 2011-05-09 | 2015-06-23 | E I Du Pont De Nemours And Company | Methods and compositions for silencing gene families using artificial microRNAs |
| AR088562A1 (es) | 2011-10-28 | 2014-06-18 | Du Pont | Metodos y composiciones para silenciar genes usando micro arn artificiales |
| CN104114707A (zh) | 2011-12-22 | 2014-10-22 | 纳幕尔杜邦公司 | 使用大豆蔗糖合酶启动子来增加植物种子脂质含量 |
| CA2862477A1 (en) | 2012-01-23 | 2013-08-01 | Linnaeus Plant Sciences Inc. | Modifying the fatty acid profile of camelina sativa oil |
| ES2635115T3 (es) | 2012-01-23 | 2017-10-02 | E. I. Du Pont De Nemours And Company | Regulación por disminución de expresión génica utilizando micro ARN artificiales para silenciar genes biosintéticos de ácidos grasos |
| WO2013158032A1 (en) | 2012-04-19 | 2013-10-24 | Temasek Life Sciences Laboratory Limited | Methods for increasing cotton fiber length |
| US10174323B2 (en) | 2012-05-16 | 2019-01-08 | The General Hospital Corporation | Compositions and methods for modulating ATP2A2 expression |
| WO2013173608A1 (en) | 2012-05-16 | 2013-11-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating mecp2 expression |
| WO2013173599A1 (en) * | 2012-05-16 | 2013-11-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating hemoglobin gene family expression |
| KR20160074368A (ko) | 2012-05-16 | 2016-06-28 | 라나 테라퓨틱스, 인크. | Utrn 발현을 조절하기 위한 조성물 및 방법 |
| US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
| CN104540947A (zh) | 2012-05-16 | 2015-04-22 | Rana医疗有限公司 | 用于调节smn基因家族表达的组合物和方法 |
| CA2905377A1 (en) | 2013-03-11 | 2014-10-09 | Pioneer Hi-Bred International, Inc. | Methods and compositions to improve the spread of chemical signals in plants |
| US20160024518A1 (en) | 2013-03-13 | 2016-01-28 | Brian McGonigle | Production of small interfering rnas in planta |
| UA121847C2 (uk) | 2013-03-14 | 2020-08-10 | Піонір Хай-Бред Інтернешнл Інк. | Полінуклеотид, що кодує елемент сайленсингу з інсектицидною активністю проти шкідника рослин із ряду coleoptera, та спосіб його застосування |
| EP3027756A1 (en) | 2013-07-31 | 2016-06-08 | E. I. du Pont de Nemours and Company | Modification of soybean seed composition to enhance feed, food and other industrial applications of soybean products |
| US10053702B2 (en) | 2014-04-22 | 2018-08-21 | E I Du Pont De Nemours And Company | Plastidic carbonic anhydrase genes for oil augmentation in seeds with increased DGAT expression |
| EP3842535A1 (en) | 2014-04-30 | 2021-06-30 | Fondazione Edmund Mach | Plant srna extract or plant mirna for use as immunosuppressive agent |
| WO2016044092A1 (en) | 2014-09-17 | 2016-03-24 | Pioneer Hi Bred International Inc | Compositions and methods to control insect pests |
| EP3209775A4 (en) | 2014-10-22 | 2018-09-12 | Temasek Life Sciences Laboratory Limited | Terpene synthases from ylang ylang (cananga odorata var. fruticosa) |
| WO2016130943A1 (en) | 2015-02-13 | 2016-08-18 | Rana Therapeutics, Inc. | Hybrid oligonucleotides and uses thereof |
| CN107771181A (zh) | 2015-06-16 | 2018-03-06 | 先锋国际良种公司 | 用以防治昆虫有害生物的组合物和方法 |
| AU2016344384A1 (en) | 2015-10-26 | 2018-05-17 | Translate Bio Ma, Inc. | Nanoparticle formulations for delivery of nucleic acid complexes |
| US20190185867A1 (en) | 2016-06-16 | 2019-06-20 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| US20210292778A1 (en) | 2016-07-12 | 2021-09-23 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| BR112019016394A2 (pt) | 2017-02-08 | 2020-04-07 | Pioneer Hi Bred Int | construto de dna, pilha molecular, pilha de melhoramento, planta transgênica ou progênie da mesma, composição e método para controlar uma população de praga de inseto |
| US20200165626A1 (en) | 2017-10-13 | 2020-05-28 | Pioneer Hi-Bred International, Inc. | Virus-induced gene silencing technology for insect control in maize |
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| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5569597A (en) | 1985-05-13 | 1996-10-29 | Ciba Geigy Corp. | Methods of inserting viral DNA into plant material |
| US5268463A (en) | 1986-11-11 | 1993-12-07 | Jefferson Richard A | Plant promoter α-glucuronidase gene construct |
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| US5316931A (en) | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5990387A (en) | 1988-06-10 | 1999-11-23 | Pioneer Hi-Bred International, Inc. | Stable transformation of plant cells |
| US5023179A (en) | 1988-11-14 | 1991-06-11 | Eric Lam | Promoter enhancer element for gene expression in plant roots |
| US5110732A (en) | 1989-03-14 | 1992-05-05 | The Rockefeller University | Selective gene expression in plants |
| HU218717B (hu) | 1989-03-17 | 2000-11-28 | E. I. Du Pont De Nemours And Co. | Nukleinsav-termelést fokozó növényi eredetű génfragmentek és eljárás előállításukra |
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| US5498830A (en) | 1990-06-18 | 1996-03-12 | Monsanto Company | Decreased oil content in plant seeds |
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| US5459252A (en) | 1991-01-31 | 1995-10-17 | North Carolina State University | Root specific gene promoter |
| US5399680A (en) | 1991-05-22 | 1995-03-21 | The Salk Institute For Biological Studies | Rice chitinase promoter |
| ATE186571T1 (de) | 1991-08-27 | 1999-11-15 | Novartis Ag | Proteine mit insektiziden eigenschaften gegen homopteran insekten und ihre verwendung im pflanzenschutz |
| ZA927576B (en) | 1991-10-04 | 1993-04-16 | Univ North Carolina State | Pathogen-resistant transgenic plants. |
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| IL108241A (en) | 1992-12-30 | 2000-08-13 | Biosource Genetics Corp | Plant expression system comprising a defective tobamovirus replicon integrated into the plant chromosome and a helper virus |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| US5789156A (en) | 1993-06-14 | 1998-08-04 | Basf Ag | Tetracycline-regulated transcriptional inhibitors |
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| US5633363A (en) | 1994-06-03 | 1997-05-27 | Iowa State University, Research Foundation In | Root preferential promoter |
| US5736369A (en) | 1994-07-29 | 1998-04-07 | Pioneer Hi-Bred International, Inc. | Method for producing transgenic cereal plants |
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| WO2003027243A2 (en) | 2001-09-27 | 2003-04-03 | Pioneer Hi-Bred International, Inc. | Phytate polynucleotides and methods of use |
| WO2004009779A2 (en) | 2002-07-19 | 2004-01-29 | University Of South Carolina | Compositions and methods for the modulation of gene expression in plants |
| CA2541914C (en) * | 2003-10-09 | 2012-07-24 | E.I. Du Pont De Nemours And Company | Gene silencing by using micro-rna molecules |
| US20060135758A1 (en) * | 2004-08-31 | 2006-06-22 | Kunsheng Wu | Soybean polymorphisms and methods of genotyping |
| US8314290B2 (en) * | 2004-12-21 | 2012-11-20 | Monsanto Technology Llc | Temporal regulation of gene expression by MicroRNAs |
| EP1824967B1 (en) | 2004-12-21 | 2014-11-05 | Monsanto Technology, LLC | Recombinant dna constructs and methods for controlling gene expression |
| US20060200878A1 (en) * | 2004-12-21 | 2006-09-07 | Linda Lutfiyya | Recombinant DNA constructs and methods for controlling gene expression |
| KR100918296B1 (ko) | 2007-12-14 | 2009-09-18 | 한국전자통신연구원 | 착신 전환 서비스 제공 시스템 및 방법 |
| US8937217B2 (en) * | 2007-12-18 | 2015-01-20 | E. I. Du Pont De Nemours And Company | Down-regulation of gene expression using artificial microRNAs |
-
2008
- 2008-12-16 US US12/335,717 patent/US8937217B2/en active Active
- 2008-12-17 ES ES10009217T patent/ES2388489T3/es active Active
- 2008-12-17 ES ES12156244T patent/ES2421031T3/es active Active
- 2008-12-17 EP EP10009228.7A patent/EP2261363B1/en not_active Not-in-force
- 2008-12-17 EP EP10009217A patent/EP2270183B1/en not_active Not-in-force
- 2008-12-17 US US12/809,324 patent/US20110091975A1/en not_active Abandoned
- 2008-12-17 BR BRPI0819526A patent/BRPI0819526B8/pt active IP Right Grant
- 2008-12-17 CA CA2709404A patent/CA2709404C/en not_active Expired - Fee Related
- 2008-12-17 EP EP08862105A patent/EP2229447A2/en not_active Withdrawn
- 2008-12-17 PL PL10009228.7T patent/PL2261363T3/pl unknown
- 2008-12-17 CA CA2902723A patent/CA2902723C/en not_active Expired - Fee Related
- 2008-12-17 CA CA2902719A patent/CA2902719C/en not_active Expired - Fee Related
- 2008-12-17 EP EP12156244.1A patent/EP2458010B1/en not_active Not-in-force
- 2008-12-17 WO PCT/US2008/087082 patent/WO2009079532A2/en not_active Ceased
-
2014
- 2014-12-11 US US14/567,568 patent/US9546374B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2261363B1 (en) | 2016-04-20 |
| EP2261363A2 (en) | 2010-12-15 |
| ES2388489T3 (es) | 2012-10-15 |
| BRPI0819526B1 (pt) | 2018-03-06 |
| US20150087069A1 (en) | 2015-03-26 |
| EP2458010B1 (en) | 2013-05-01 |
| EP2270183B1 (en) | 2012-06-13 |
| PL2261363T3 (pl) | 2016-12-30 |
| CA2902719C (en) | 2016-10-18 |
| EP2261363A8 (en) | 2011-02-16 |
| BRPI0819526B8 (pt) | 2022-12-06 |
| US20110091975A1 (en) | 2011-04-21 |
| EP2270183A3 (en) | 2011-03-16 |
| EP2458010A1 (en) | 2012-05-30 |
| WO2009079532A3 (en) | 2009-09-17 |
| US20090155910A1 (en) | 2009-06-18 |
| EP2229447A2 (en) | 2010-09-22 |
| EP2261363A3 (en) | 2011-03-16 |
| CA2902723C (en) | 2016-10-18 |
| CA2902723A1 (en) | 2009-06-25 |
| US8937217B2 (en) | 2015-01-20 |
| ES2421031T3 (es) | 2013-08-28 |
| US9546374B2 (en) | 2017-01-17 |
| WO2009079532A2 (en) | 2009-06-25 |
| CA2902719A1 (en) | 2009-06-25 |
| CA2709404C (en) | 2016-10-11 |
| CA2709404A1 (en) | 2009-06-25 |
| EP2270183A2 (en) | 2011-01-05 |
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