BRPI0816750A2 - métodos para alterar o genoma de uma célula de planta monocotiledônea e para modificar uma sequência alvo genômica endógena específica e planta de milho - Google Patents
métodos para alterar o genoma de uma célula de planta monocotiledônea e para modificar uma sequência alvo genômica endógena específica e planta de milhoInfo
- Publication number
- BRPI0816750A2 BRPI0816750A2 BRPI0816750A BRPI0816750A BRPI0816750A2 BR PI0816750 A2 BRPI0816750 A2 BR PI0816750A2 BR PI0816750 A BRPI0816750 A BR PI0816750A BR PI0816750 A BRPI0816750 A BR PI0816750A BR PI0816750 A2 BRPI0816750 A2 BR PI0816750A2
- Authority
- BR
- Brazil
- Prior art keywords
- genome
- altering
- modifying
- methods
- target sequence
- Prior art date
Links
- 241000196324 Embryophyta Species 0.000 title 1
- 240000008042 Zea mays Species 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/13—Plant traits
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94700307P | 2007-06-29 | 2007-06-29 | |
| US3315008P | 2008-03-03 | 2008-03-03 | |
| PCT/US2008/068570 WO2009006297A2 (en) | 2007-06-29 | 2008-06-27 | Methods for altering the genome of a monocot plant cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0816750A2 true BRPI0816750A2 (pt) | 2015-09-29 |
Family
ID=39865253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0816750A BRPI0816750A2 (pt) | 2007-06-29 | 2008-06-27 | métodos para alterar o genoma de uma célula de planta monocotiledônea e para modificar uma sequência alvo genômica endógena específica e planta de milho |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8912392B2 (pt) |
| EP (2) | EP2167666A2 (pt) |
| CN (1) | CN101849010A (pt) |
| BR (1) | BRPI0816750A2 (pt) |
| CA (1) | CA2691440A1 (pt) |
| WO (1) | WO2009006297A2 (pt) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003078619A1 (en) † | 2002-03-15 | 2003-09-25 | Cellectis | Hybrid and single chain meganucleases and use thereof |
| US20120196370A1 (en) * | 2010-12-03 | 2012-08-02 | Fyodor Urnov | Methods and compositions for targeted genomic deletion |
| BRPI0816750A2 (pt) | 2007-06-29 | 2015-09-29 | Pioneer Hi Bred Int | métodos para alterar o genoma de uma célula de planta monocotiledônea e para modificar uma sequência alvo genômica endógena específica e planta de milho |
| ES2575412T3 (es) | 2007-10-31 | 2016-06-28 | Precision Biosciences, Inc. | Meganucleasas monocatenarias diseñadas racionalmente con secuencias de reconocimiento no palindrómicas |
| WO2009114321A2 (en) | 2008-03-11 | 2009-09-17 | Precision Biosciencs, Inc. | Rationally-designed meganucleases for maize genome engineering |
| JP2011527906A (ja) | 2008-07-14 | 2011-11-10 | プレシジョン バイオサイエンシズ，インク． | Ｉ−ＣｒｅＩ由来メガヌクレアーゼの認識配列およびその使用 |
| GB2467167B (en) * | 2009-01-26 | 2013-09-11 | Algentech Sas | Gene targeting in plants |
| CN102762726A (zh) | 2009-11-27 | 2012-10-31 | 巴斯夫植物科学有限公司 | 嵌合内切核酸酶及其用途 |
| EP2504429B1 (en) | 2009-11-27 | 2016-04-20 | BASF Plant Science Company GmbH | Chimeric endonucleases and uses thereof |
| WO2011078662A1 (en) * | 2009-12-21 | 2011-06-30 | Keygene N.V. | Dsrna for improved genetic modification of plant dna |
| AU2010339481B2 (en) | 2009-12-30 | 2016-02-04 | Pioneer Hi-Bred International, Inc. | Methods and compositions for targeted polynucleotide modification |
| US20110203012A1 (en) * | 2010-01-21 | 2011-08-18 | Dotson Stanton B | Methods and compositions for use of directed recombination in plant breeding |
| EP2525649B1 (en) * | 2010-01-22 | 2020-01-08 | Dow AgroSciences, LLC | Excision of transgenes in genetically modified organisms |
| EP2526199A4 (en) * | 2010-01-22 | 2013-08-07 | Scripps Research Inst | PROCESS FOR PRODUCING ZINC FINGERUCLEASES WITH CHANGED EFFECT |
| CN103237894A (zh) | 2010-08-13 | 2013-08-07 | 先锋国际良种公司 | 包含具有羟基苯丙酮酸双加氧酶(hppd)活性的序列的组合物和方法 |
| AR084844A1 (es) | 2011-01-14 | 2013-06-26 | Jones Jeffrey B | Arboles de citricos con resistencia a cancro de los citricos |
| WO2012129373A2 (en) * | 2011-03-23 | 2012-09-27 | Pioneer Hi-Bred International, Inc. | Methods for producing a complex transgenic trait locus |
| EP2718443B1 (en) | 2011-06-06 | 2017-11-29 | Bayer CropScience NV | Methods and means to modify a plant genome at a preselected site |
| CN103620027B (zh) | 2011-06-10 | 2017-11-21 | 巴斯夫植物科学有限公司 | 核酸酶融合蛋白及其用途 |
| MX2013015174A (es) | 2011-06-21 | 2014-09-22 | Pioneer Hi Bred Int | Metodos y composiciones para producir plantas esteriles masculinas. |
| US20130097734A1 (en) | 2011-07-12 | 2013-04-18 | Two Blades Foundation | Late blight resistance genes |
| CA2844101A1 (en) * | 2011-08-03 | 2013-02-07 | E. I. Du Pont De Nemours And Company | Methods and compositions for targeted integration in a plant |
| MX348003B (es) | 2011-08-22 | 2017-03-08 | Bayer Cropscience Nv | Metodos y medios para modificar un genoma vegetal. |
| WO2013043638A1 (en) * | 2011-09-23 | 2013-03-28 | Iowa State University Research Foundation, Inc. | Monomer architecture of tal nuclease or zinc finger nuclease for dna modification |
| WO2013103366A1 (en) | 2012-01-06 | 2013-07-11 | Pioneer Hi-Bred International, Inc. | A method to screen plants for genetic elements inducing parthenogenesis in plants |
| BR112014018294B1 (pt) | 2012-01-26 | 2022-01-11 | Norfolk Plant Sciences, Ltd | Método para produzir uma planta, cassete de expressão, e, célula bacteriana |
| AR089793A1 (es) | 2012-01-27 | 2014-09-17 | Du Pont | Metodos y composiciones para generar locus de rasgos transgenicos complejos |
| CA2872096A1 (en) * | 2012-05-04 | 2013-11-07 | E. I. Du Pont De Nemours And Company | Compositions and methods comprising sequences having meganuclease activity |
| US20150225734A1 (en) * | 2012-06-19 | 2015-08-13 | Regents Of The University Of Minnesota | Gene targeting in plants using dna viruses |
| EP2687605A1 (en) * | 2012-07-19 | 2014-01-22 | Biogemma | Method for performing homologous recombination |
| UA119135C2 (uk) * | 2012-09-07 | 2019-05-10 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб отримання трансгенної рослини |
| WO2014164466A1 (en) * | 2013-03-12 | 2014-10-09 | E. I. Du Pont De Nemours And Company | Methods for the identification of variant recognition sites for rare-cutting engineered double-strand-break-inducing agents and compositions and uses thereof |
| AU2014227831B2 (en) * | 2013-03-15 | 2020-01-30 | Regents Of The University Of Minnesota | Engineering plant genomes using CRISPR/Cas systems |
| LT3036327T (lt) | 2013-08-22 | 2019-06-25 | Pioneer Hi-Bred International, Inc. | Genomo modifikacijos, panaudojant nukreipiančias polinukleotido/cas endonukleazės sistemas, ir panaudojimo būdai |
| CA2928830A1 (en) | 2013-10-29 | 2015-05-07 | Shai J. Lawit | Self-reproducing hybrid plants |
| JP6649261B2 (ja) | 2013-11-04 | 2020-02-19 | ダウ アグロサイエンシィズ エルエルシー | 最適なトウモロコシ遺伝子座 |
| CA2926822C (en) * | 2013-11-04 | 2022-12-13 | Dow Agrosciences Llc | Optimal soybean loci |
| AU2014341934B2 (en) | 2013-11-04 | 2017-12-07 | Corteva Agriscience Llc | Optimal soybean loci |
| AU2014341929B2 (en) | 2013-11-04 | 2017-11-30 | Corteva Agriscience Llc | Optimal maize loci |
| US20170166920A1 (en) | 2014-01-30 | 2017-06-15 | Two Blades Foundation | Plants with enhanced resistance to phytophthora |
| KR20160145649A (ko) * | 2014-04-28 | 2016-12-20 | 다우 아그로사이언시즈 엘엘씨 | 반수체 메이즈 형질전환 |
| WO2015171603A1 (en) | 2014-05-06 | 2015-11-12 | Two Blades Foundation | Methods for producing plants with enhanced resistance to oomycete pathogens |
| EP3919621A1 (en) * | 2014-06-23 | 2021-12-08 | The General Hospital Corporation | Genomewide unbiased identification of dsbs evaluated by sequencing (guide-seq) |
| BR112017000482A2 (pt) | 2014-07-11 | 2017-11-07 | Du Pont | métodos para produzir uma planta mutante e para gerar uma planta, planta, semente, rna, métodos para produzir uma célula, para duplicar um fragmento gênico, para substituir uma primeira sequência promotora, para inserir um elemento regulador em uma sequência de nucleotídeos e para inserir um íntron em uma sequência de nucleotídeos, planta de milho e célula vegetal |
| WO2016040030A1 (en) | 2014-09-12 | 2016-03-17 | E. I. Du Pont De Nemours And Company | Generation of site-specific-integration sites for complex trait loci in corn and soybean, and methods of use |
| CN113337533A (zh) | 2014-12-23 | 2021-09-03 | 先正达参股股份有限公司 | 用于鉴定和富集包含位点特异性基因组修饰的细胞的方法和组合物 |
| WO2016137774A1 (en) | 2015-02-25 | 2016-09-01 | Pioneer Hi-Bred International Inc | Composition and methods for regulated expression of a guide rna/cas endonuclease complex |
| CN107429258A (zh) * | 2015-03-19 | 2017-12-01 | 先锋国际良种公司 | 用于加速的性状渐渗的方法和组合物 |
| EP3274460A1 (en) | 2015-03-27 | 2018-01-31 | E. I. du Pont de Nemours and Company | Soybean u6 small nuclear rna gene promoters and their use in constitutive expression of small rna genes in plants |
| CN107709564B (zh) | 2015-05-09 | 2021-11-02 | 双刃基金会 | 来自少花龙葵的抗晚疫病基因及使用方法 |
| AR105776A1 (es) * | 2015-08-21 | 2017-11-08 | Monsanto Technology Llc | Recombinación mejorada de loci genómicos |
| WO2017062790A1 (en) | 2015-10-09 | 2017-04-13 | Two Blades Foundation | Cold shock protein receptors and methods of use |
| US11330776B2 (en) | 2015-10-30 | 2022-05-17 | Pioneer Hi-Bred International, Inc. | Methods and compositions for rapid plant transformation |
| EP3371313B1 (en) | 2015-11-06 | 2020-10-14 | Pioneer Hi-Bred International, Inc. | Methods and compositions of improved plant transformation |
| US11104911B2 (en) | 2015-12-22 | 2021-08-31 | Pioneer Hi-Bred International, Inc. | Embryo-preferred Zea mays promoters and methods of use |
| EP3426778A1 (en) | 2016-03-11 | 2019-01-16 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
| CN106701820A (zh) * | 2016-12-20 | 2017-05-24 | 安徽省农业科学院水稻研究所 | 一种野生稻关键基因的改良和利用方法 |
| EP3456829A1 (en) * | 2017-09-18 | 2019-03-20 | Nomad Bioscience GmbH | Method of improving potexviral vector stability |
| CN111373046A (zh) | 2017-09-25 | 2020-07-03 | 先锋国际良种公司 | 组织偏好性启动子和使用方法 |
| CA3078819A1 (en) | 2017-10-13 | 2019-04-18 | Pioneer Hi-Bred International, Inc. | Systems and methods for cellular reprogramming of a plant cell |
| WO2019108619A1 (en) | 2017-11-28 | 2019-06-06 | Two Blades Foundation | Methods and compositions for enhancing the disease resistance of plants |
| US20210054389A1 (en) | 2017-12-27 | 2021-02-25 | Pioneer Hi-Bred International, Inc. | Transformation of dicot plants |
| CN111954464A (zh) | 2018-01-12 | 2020-11-17 | 双刃基金会 | 秆锈病抗性基因及使用方法 |
| EP3755792A4 (en) | 2018-02-23 | 2021-12-08 | Pioneer Hi-Bred International, Inc. | NEW CASE ORTHOLOGISTS9 |
| BR112020018644A2 (pt) | 2018-03-12 | 2020-12-29 | Pioneer Hi-Bred International, Inc. | Uso de fatores morfogênicos para o aprimoramento de edição de genes |
| CA3097915A1 (en) | 2018-06-28 | 2020-01-02 | Pioneer Hi-Bred International, Inc. | Methods for selecting transformed plants |
| AU2019369415A1 (en) | 2018-10-31 | 2021-03-25 | Pioneer Hi-Bred International, Inc. | Compositions and methods for Ochrobactrum-mediated plant transformation |
| AU2019398351B2 (en) | 2018-12-14 | 2026-01-29 | Pioneer Hi-Bred International, Inc. | Novel CRISPR-Cas systems for genome editing |
| WO2020157164A1 (en) | 2019-01-30 | 2020-08-06 | Enobraq | Modified plant with improved rubisco activity |
| US20220170033A1 (en) | 2019-03-27 | 2022-06-02 | Pioneer Hi-Bred International, Inc. | Plant explant transformation |
| US12415984B2 (en) | 2019-03-28 | 2025-09-16 | Pioneer Hi-Bred International, Inc. | Modified Agrobacterium strains and use thereof for plant transformation |
| US20220251595A1 (en) | 2019-06-27 | 2022-08-11 | Two Blades Foundation | Engineered atrlp23 pattern recognition receptors and methods of use |
| US20210071193A1 (en) | 2019-07-12 | 2021-03-11 | The Regents Of The University Of California | Plants with enhanced resistance to bacterial pathogens |
| BR112022016917A2 (pt) | 2020-02-24 | 2022-10-25 | Pioneer Hi Bred Int | Recombinação homóloga intragenômica |
| IL301685A (en) | 2020-09-30 | 2023-05-01 | Corteva Agriscience Llc | Rapid transformation of monocot leaf explants |
| WO2022240931A1 (en) | 2021-05-11 | 2022-11-17 | Two Blades Foundation | Methods for preparing a library of plant disease resistance genes for functional testing for disease resistance |
| WO2023056269A1 (en) | 2021-09-30 | 2023-04-06 | Two Blades Foundation | Plant disease resistance genes against stem rust and methods of use |
| EP4441208A1 (en) | 2021-11-30 | 2024-10-09 | Pioneer Hi-Bred International, Inc. | High efficiency large scale chromosomal genome manipulation |
| KR20250160500A (ko) | 2023-03-20 | 2025-11-13 | 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 | 변경된 pam 인식을 갖는 cas 폴리펩티드 |
| WO2025019283A1 (en) | 2023-07-14 | 2025-01-23 | Two Blades Foundation | Methods of improving the thermostability of plant immune receptors |
| WO2025019221A1 (en) | 2023-07-15 | 2025-01-23 | Two Blades Foundation | Broad-spectrum polerovirus resistance gene |
Family Cites Families (109)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5567600A (en) * | 1983-09-26 | 1996-10-22 | Mycogen Plant Sciences, Inc. | Synthetic insecticidal crystal protein gene |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5569597A (en) | 1985-05-13 | 1996-10-29 | Ciba Geigy Corp. | Methods of inserting viral DNA into plant material |
| US5107065A (en) | 1986-03-28 | 1992-04-21 | Calgene, Inc. | Anti-sense regulation of gene expression in plant cells |
| US5268463A (en) | 1986-11-11 | 1993-12-07 | Jefferson Richard A | Plant promoter α-glucuronidase gene construct |
| US5608142A (en) | 1986-12-03 | 1997-03-04 | Agracetus, Inc. | Insecticidal cotton plants |
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| EP0317509A3 (de) | 1987-11-16 | 1990-01-31 | Ciba-Geigy Ag | Gezielter Einbau von Genen ins pflanzliche Genom |
| US5316931A (en) | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5990387A (en) | 1988-06-10 | 1999-11-23 | Pioneer Hi-Bred International, Inc. | Stable transformation of plant cells |
| US5023179A (en) | 1988-11-14 | 1991-06-11 | Eric Lam | Promoter enhancer element for gene expression in plant roots |
| US5110732A (en) | 1989-03-14 | 1992-05-05 | The Rockefeller University | Selective gene expression in plants |
| FR2646438B1 (fr) * | 1989-03-20 | 2007-11-02 | Pasteur Institut | Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration |
| US5240855A (en) | 1989-05-12 | 1993-08-31 | Pioneer Hi-Bred International, Inc. | Particle gun |
| US5879918A (en) | 1989-05-12 | 1999-03-09 | Pioneer Hi-Bred International, Inc. | Pretreatment of microprojectiles prior to using in a particle gun |
| US5322783A (en) | 1989-10-17 | 1994-06-21 | Pioneer Hi-Bred International, Inc. | Soybean transformation by microparticle bombardment |
| EP0452269B1 (en) | 1990-04-12 | 2002-10-09 | Syngenta Participations AG | Tissue-preferential promoters |
| US5498830A (en) | 1990-06-18 | 1996-03-12 | Monsanto Company | Decreased oil content in plant seeds |
| ATE256192T1 (de) | 1990-06-23 | 2003-12-15 | Bayer Cropscience Gmbh | Fertile transgene maispflanzen mit artfremdem gen sowie verfahren zu ihrer herstellung |
| US5932782A (en) | 1990-11-14 | 1999-08-03 | Pioneer Hi-Bred International, Inc. | Plant transformation method using agrobacterium species adhered to microprojectiles |
| US5459252A (en) | 1991-01-31 | 1995-10-17 | North Carolina State University | Root specific gene promoter |
| US5399680A (en) | 1991-05-22 | 1995-03-21 | The Salk Institute For Biological Studies | Rice chitinase promoter |
| GB9114259D0 (en) | 1991-07-02 | 1991-08-21 | Ici Plc | Plant derived enzyme and dna sequences |
| ATE186571T1 (de) | 1991-08-27 | 1999-11-15 | Novartis Ag | Proteine mit insektiziden eigenschaften gegen homopteran insekten und ihre verwendung im pflanzenschutz |
| ZA927576B (en) | 1991-10-04 | 1993-04-16 | Univ North Carolina State | Pathogen-resistant transgenic plants. |
| US5324646A (en) | 1992-01-06 | 1994-06-28 | Pioneer Hi-Bred International, Inc. | Methods of regeneration of Medicago sativa and expressing foreign DNA in same |
| US5792632A (en) * | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| US5474896A (en) * | 1992-05-05 | 1995-12-12 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| US5401836A (en) | 1992-07-16 | 1995-03-28 | Pioneer Hi-Bre International, Inc. | Brassica regulatory sequence for root-specific or root-abundant gene expression |
| EP0652965A1 (en) | 1992-07-27 | 1995-05-17 | Pioneer Hi-Bred International, Inc. | An improved method of agrobacterium-mediated transformation of cultured soybean cells |
| DE69333667T2 (de) | 1992-12-09 | 2006-02-02 | New England Biolabs, Inc., Beverly | Kontrollierbare Zwischensequenzen enthaltende modifizierte Proteine und Verfahren zur deren Herstellung |
| IL108241A (en) | 1992-12-30 | 2000-08-13 | Biosource Genetics Corp | Plant expression system comprising a defective tobamovirus replicon integrated into the plant chromosome and a helper virus |
| US5527695A (en) * | 1993-01-29 | 1996-06-18 | Purdue Research Foundation | Controlled modification of eukaryotic genomes |
| US5789156A (en) | 1993-06-14 | 1998-08-04 | Basf Ag | Tetracycline-regulated transcriptional inhibitors |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US5633363A (en) | 1994-06-03 | 1997-05-27 | Iowa State University, Research Foundation In | Root preferential promoter |
| US5736369A (en) | 1994-07-29 | 1998-04-07 | Pioneer Hi-Bred International, Inc. | Method for producing transgenic cereal plants |
| US5608144A (en) | 1994-08-12 | 1997-03-04 | Dna Plant Technology Corp. | Plant group 2 promoters and uses thereof |
| US5659026A (en) | 1995-03-24 | 1997-08-19 | Pioneer Hi-Bred International | ALS3 promoter |
| US5888732A (en) | 1995-06-07 | 1999-03-30 | Life Technologies, Inc. | Recombinational cloning using engineered recombination sites |
| US5837876A (en) | 1995-07-28 | 1998-11-17 | North Carolina State University | Root cortex specific gene promoter |
| US6051409A (en) * | 1995-09-25 | 2000-04-18 | Novartis Finance Corporation | Method for achieving integration of exogenous DNA delivered by non-biological means to plant cells |
| US6175056B1 (en) | 1996-04-29 | 2001-01-16 | The Procter & Gamble Company | Disposable absorbent article having an expanding topsheet and being capable of self-shaping in use |
| US6072050A (en) | 1996-06-11 | 2000-06-06 | Pioneer Hi-Bred International, Inc. | Synthetic promoters |
| WO1998001575A1 (en) | 1996-07-08 | 1998-01-15 | Pioneer Hi-Bred International, Inc. | Transformation of zygote, egg or sperm cells and recovery of transformed plants from isolated embryo sacs |
| US5981840A (en) | 1997-01-24 | 1999-11-09 | Pioneer Hi-Bred International, Inc. | Methods for agrobacterium-mediated transformation |
| US6369298B1 (en) | 1997-04-30 | 2002-04-09 | Pioneer Hi-Bred International, Inc. | Agrobacterium mediated transformation of sorghum |
| US7135608B1 (en) * | 1997-08-28 | 2006-11-14 | The Salk Institute For Biological Studies | Site-specific recombination in eukaryotes and constructs useful therefor |
| US6114600A (en) * | 1997-10-31 | 2000-09-05 | The United States Of America As Represented By The Secretary Of Agriculture | Resolution of complex integration patterns to obtain single copy transgenes |
| JP4206154B2 (ja) | 1997-11-13 | 2009-01-07 | 大日本住友製薬株式会社 | 変異型ｌｏｘＰ配列とその応用 |
| DE19750475C1 (de) | 1997-11-14 | 1999-04-08 | Treibacher Schleifmittel Ag | Verfahren und Aggregat zur thermischen Behandlung von feinkörnigen Stoffen |
| AU757672B2 (en) | 1997-11-18 | 2003-02-27 | Pioneer Hi-Bred International, Inc. | A method for directional stable transformation of eukaryotic cells |
| US5929301A (en) | 1997-11-18 | 1999-07-27 | Pioneer Hi-Bred International | Nucleic acid sequence encoding FLP recombinase |
| EP1034286B1 (en) | 1997-11-18 | 2010-01-06 | Pioneer Hi-Bred International, Inc. | Mobilization of viral genomes from t-dna using site-specific recombination systems |
| ATE317440T1 (de) | 1997-11-18 | 2006-02-15 | Pioneer Hi Bred Int | Neuartige methode zur integration von fremd-dna ins eukaryotische genom |
| DE69932868T2 (de) | 1998-02-26 | 2007-03-15 | Pioneer Hi-Bred International, Inc. | Nukleinsäuremolekül mit einer Nukleotidsequenz für einen Promotor |
| WO1999055851A2 (en) | 1998-04-28 | 1999-11-04 | Novartis Ag | Site-directed transformation of plants |
| US6781032B1 (en) * | 1998-08-14 | 2004-08-24 | The Regents Of The University Of California | Homologous recombination in plants |
| WO2000011177A1 (en) | 1998-08-20 | 2000-03-02 | Pioneer Hi-Bred International, Inc. | Seed-preferred promoters |
| WO2000012734A1 (en) * | 1998-08-28 | 2000-03-09 | The Regents Of The University Of California | Transposon tagging and gene delivery in small grain cereals |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| WO2000046386A2 (en) | 1999-02-03 | 2000-08-10 | The Children's Medical Center Corporation | Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site |
| JP2002535994A (ja) * | 1999-02-03 | 2002-10-29 | ザ チルドレンズ メディカル センター コーポレイション | 標的ｄｎａのインビボ除去による遺伝子修復 |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| US6746870B1 (en) * | 1999-07-23 | 2004-06-08 | The Regents Of The University Of California | DNA recombination in eukaryotic cells by the bacteriophage PHIC31 recombination system |
| DE60044142D1 (de) | 1999-07-23 | 2010-05-20 | Univ California | Dna-rekombination in eukaryotischen zellen mittels des rekombinationszentrums vom bakteriophag phic31 |
| WO2001011058A1 (en) | 1999-08-09 | 2001-02-15 | Monsanto Technology Llc | Novel cloning methods and vectors |
| AU7447000A (en) * | 1999-09-30 | 2001-04-30 | Izumu Saito | Dna containing variant frt sequences |
| US7126041B1 (en) * | 1999-12-10 | 2006-10-24 | North Carolina State Unversity | High efficiency gene targeting in plants |
| WO2001083819A2 (en) | 2000-04-28 | 2001-11-08 | Sangamo Biosciences, Inc. | Methods for designing exogenous regulatory molecules |
| US20030082561A1 (en) | 2000-07-21 | 2003-05-01 | Takashi Sera | Zinc finger domain recognition code and uses thereof |
| CN1455817A (zh) * | 2000-07-21 | 2003-11-12 | (由农业部部长代表的)美利坚合众国 | 用于在真核基因组中置换、转移和富积dna的方法 |
| DK1353941T3 (da) | 2001-01-22 | 2013-06-17 | Sangamo Biosciences Inc | Modificerede zinkfingerbindingsproteiner |
| GB0108491D0 (en) | 2001-04-04 | 2001-05-23 | Gendaq Ltd | Engineering zinc fingers |
| DE10131786A1 (de) | 2001-07-04 | 2003-01-16 | Sungene Gmbh & Co Kgaa | Rekombinationssysteme und Verfahren zum Entfernen von Nukleinsäuresequenzen aus dem Genom eukaryotischer Organismen |
| AT5356U1 (de) | 2001-07-16 | 2002-06-25 | Uv & P Umweltman Verfahrenstec | Verfahren zur immobilisierung von verbrennungsrückständen |
| AU2002333832B2 (en) | 2001-09-14 | 2007-07-26 | Cellectis | Random integration of a polynucleotide after in vivo linearization |
| GB0126251D0 (en) | 2001-11-01 | 2002-01-02 | Imp College Innovations Ltd | Methods |
| BRPI0307383B1 (pt) | 2002-01-23 | 2019-12-31 | The Univ Of Utah Research Foundation | método de recombinação genética direcionada em célula de planta hospedeira |
| US20050238658A1 (en) | 2002-03-05 | 2005-10-27 | Maskell Duncan J | Transposon |
| WO2003078619A1 (en) | 2002-03-15 | 2003-09-25 | Cellectis | Hybrid and single chain meganucleases and use thereof |
| CA2480642C (en) * | 2002-03-29 | 2012-10-16 | Janet Louise Suttie | Lambda integrase mediated recombination in plants |
| FR2843404A1 (fr) | 2002-08-07 | 2004-02-13 | Cellectis | Methode de determination de l'activite de clivage d'une endonuclease |
| WO2004031346A2 (en) | 2002-09-06 | 2004-04-15 | Fred Hutchinson Cancer Research Center | Methods and compositions concerning designed highly-specific nucleic acid binding proteins |
| AU2004208031B2 (en) | 2003-01-28 | 2009-10-08 | Cellectis | Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof. |
| IES20030696A2 (en) | 2003-09-23 | 2005-03-23 | Carsphairn Ltd | A pipeline apparatus |
| JP4885727B2 (ja) * | 2003-11-18 | 2012-02-29 | バイエル・バイオサイエンス・エヌ・ヴェー | 植物における改善された標的に向けたｄｎａ挿入 |
| US7935862B2 (en) * | 2003-12-02 | 2011-05-03 | Syngenta Participations Ag | Targeted integration and stacking of DNA through homologous recombination |
| EP1591521A1 (en) | 2004-04-30 | 2005-11-02 | Cellectis | I-Dmo I derivatives with enhanced activity at 37 degrees C and use thereof |
| US20060288444A1 (en) * | 2004-08-13 | 2006-12-21 | Mccarroll Robert | Soybean polymorphisms and methods of genotyping |
| WO2006074956A1 (en) | 2005-01-14 | 2006-07-20 | Bayer Bioscience N.V. | Improved plant transformation methods |
| US7897372B2 (en) | 2005-03-15 | 2011-03-01 | Cellectis | I-CreI meganuclease variants with modified specificity, method of preparation and uses thereof |
| WO2007034262A1 (en) | 2005-09-19 | 2007-03-29 | Cellectis | Heterodimeric meganucleases and use thereof |
| WO2006097784A1 (en) | 2005-03-15 | 2006-09-21 | Cellectis | I-crei meganuclease variants with modified specificity, method of preparation and uses thereof |
| AU2006232828B2 (en) | 2005-04-04 | 2011-01-27 | Bayer Cropscience Nv. | Methods and means for removal of a selected DNA sequence |
| CN101238215A (zh) | 2005-04-05 | 2008-08-06 | 先锋高级育种国际公司 | 利用植物病毒密码子偏爱性设计用于在植物中的多肽表达的核酸分子的方法和组合物 |
| PT1885176T (pt) * | 2005-05-27 | 2016-11-28 | Monsanto Technology Llc | Evento mon89788 de soja e métodos para a sua deteção |
| EP2327774A3 (en) * | 2005-10-18 | 2011-09-28 | Precision Biosciences | Rationally-designed meganucleases with altered sequence specificity and DNA-binding affinity |
| KR101439568B1 (ko) | 2006-08-11 | 2014-09-12 | 다우 아그로사이언시즈 엘엘씨 | 아연 손가락 뉴클레아제-매개 상동 재조합 |
| US20080083042A1 (en) * | 2006-08-14 | 2008-04-03 | David Butruille | Maize polymorphisms and methods of genotyping |
| CA2664414C (en) | 2006-09-28 | 2016-07-12 | Bayer Bioscience N.V. | Methods and means for removal of a selected dna sequence |
| WO2008093152A1 (en) | 2007-02-01 | 2008-08-07 | Cellectis | Obligate heterodimer meganucleases and uses thereof |
| WO2008145731A1 (en) | 2007-05-31 | 2008-12-04 | Basf Plant Science Gmbh | Method of excising a nucleic acid sequence from a plant genome |
| CA2689345C (en) | 2007-06-05 | 2017-07-11 | Bayer Bioscience N.V. | Methods and means for exact replacement of target dna in eukaryotic organisms |
| AR067114A1 (es) * | 2007-06-22 | 2009-09-30 | Monsanto Technology Llc | Metodos y composiciones para seleccionar loci en base al rendimiento y la exresion de caracteristicas |
| AR067358A1 (es) | 2007-06-29 | 2009-10-07 | Pioneer Hi Bred Int | Metodos para alterar el genoma de una celula de una planta monocotiledonea |
| BRPI0816750A2 (pt) | 2007-06-29 | 2015-09-29 | Pioneer Hi Bred Int | métodos para alterar o genoma de uma célula de planta monocotiledônea e para modificar uma sequência alvo genômica endógena específica e planta de milho |
| WO2009114321A2 (en) | 2008-03-11 | 2009-09-17 | Precision Biosciencs, Inc. | Rationally-designed meganucleases for maize genome engineering |
-
2008
- 2008-06-27 BR BRPI0816750A patent/BRPI0816750A2/pt not_active IP Right Cessation
- 2008-06-27 CN CN200880104786.4A patent/CN101849010A/zh active Pending
- 2008-06-27 EP EP08772157A patent/EP2167666A2/en not_active Withdrawn
- 2008-06-27 US US12/147,834 patent/US8912392B2/en active Active
- 2008-06-27 EP EP12192636A patent/EP2568048A1/en not_active Withdrawn
- 2008-06-27 CA CA002691440A patent/CA2691440A1/en not_active Abandoned
- 2008-06-27 WO PCT/US2008/068570 patent/WO2009006297A2/en not_active Ceased
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2014
- 2014-11-14 US US14/541,237 patent/US20150074843A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2167666A2 (en) | 2010-03-31 |
| US8912392B2 (en) | 2014-12-16 |
| WO2009006297A2 (en) | 2009-01-08 |
| CA2691440A1 (en) | 2009-01-08 |
| EP2568048A1 (en) | 2013-03-13 |
| US20150074843A1 (en) | 2015-03-12 |
| WO2009006297A3 (en) | 2009-02-19 |
| US20090133152A1 (en) | 2009-05-21 |
| CN101849010A (zh) | 2010-09-29 |
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