UY30824A1 - Nuevos derivados de idazolil éster o amida, composiciones farmacéuticas conteniéndolas, procesos de preparacion y aplicaciones. - Google Patents
Nuevos derivados de idazolil éster o amida, composiciones farmacéuticas conteniéndolas, procesos de preparacion y aplicaciones.Info
- Publication number
- UY30824A1 UY30824A1 UY30824A UY30824A UY30824A1 UY 30824 A1 UY30824 A1 UY 30824A1 UY 30824 A UY30824 A UY 30824A UY 30824 A UY30824 A UY 30824A UY 30824 A1 UY30824 A1 UY 30824A1
- Authority
- UY
- Uruguay
- Prior art keywords
- pharmaceutical compositions
- ester
- idazolil
- amida
- applications
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 derivatives of indazolyl ester Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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Abstract
Compuestos de formula (I): La presente invencion se refiere a nuevos derivados de indazolil éster o amida, a composiciones farmacéuticas que comprenden dichos derivados, a procesos para preparar dichos derivados nuevos y al uso de dichos derivados como medicamentos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87118406P | 2006-12-21 | 2006-12-21 | |
| US94174507P | 2007-06-04 | 2007-06-04 | |
| US97852607P | 2007-10-09 | 2007-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY30824A1 true UY30824A1 (es) | 2008-07-31 |
Family
ID=39536557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY30824A UY30824A1 (es) | 2006-12-21 | 2007-12-20 | Nuevos derivados de idazolil éster o amida, composiciones farmacéuticas conteniéndolas, procesos de preparacion y aplicaciones. |
Country Status (36)
| Country | Link |
|---|---|
| US (4) | US7728030B2 (es) |
| EP (1) | EP2102169B1 (es) |
| JP (2) | JP5119267B2 (es) |
| KR (1) | KR20090091354A (es) |
| CN (1) | CN101611015B (es) |
| AR (1) | AR064505A1 (es) |
| AU (1) | AU2007334659B2 (es) |
| CA (1) | CA2673277A1 (es) |
| CL (1) | CL2007003804A1 (es) |
| CR (1) | CR10875A (es) |
| CY (1) | CY1113269T1 (es) |
| DK (1) | DK2102169T3 (es) |
| DO (1) | DOP2009000148A (es) |
| EA (1) | EA016895B1 (es) |
| EC (1) | ECSP099452A (es) |
| ES (1) | ES2387584T3 (es) |
| GT (1) | GT200900175A (es) |
| HR (1) | HRP20120656T1 (es) |
| IL (1) | IL198880A (es) |
| JO (1) | JO2754B1 (es) |
| MA (1) | MA31087B1 (es) |
| MX (1) | MX2009006540A (es) |
| MY (1) | MY153270A (es) |
| NO (1) | NO20092723L (es) |
| NZ (1) | NZ577186A (es) |
| PE (1) | PE20081838A1 (es) |
| PL (1) | PL2102169T3 (es) |
| PT (1) | PT2102169E (es) |
| RS (1) | RS52411B (es) |
| SA (1) | SA07280740B1 (es) |
| SV (1) | SV2009003305A (es) |
| TN (1) | TN2009000250A1 (es) |
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| UY (1) | UY30824A1 (es) |
| WO (1) | WO2008076048A1 (es) |
| ZA (1) | ZA200903654B (es) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH081035Y2 (ja) | 1993-06-30 | 1996-01-17 | 伸夫 高橋 | 家庭用雑排水の処理装置 |
| FR2866886B1 (fr) * | 2004-02-26 | 2007-08-31 | Sanofi Synthelabo | Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique |
| TW200829578A (en) | 2006-11-23 | 2008-07-16 | Astrazeneca Ab | Chemical compounds 537 |
| JO2754B1 (en) * | 2006-12-21 | 2014-03-15 | استرازينكا ايه بي | Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders |
| WO2009142588A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) a chemokine receptor 1 (ccr1) antagonist and (b) glucocorticoid receptor modulator |
| WO2009142568A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) glucocorticoid receptor modulator and (b) a b2-agonist |
| WO2009142589A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
| TWI445705B (zh) * | 2008-05-20 | 2014-07-21 | Astrazeneca Ab | 經苯基及苯并二基取代之吲唑衍生物 |
| WO2010008341A1 (en) * | 2008-07-16 | 2010-01-21 | Astrazeneca Ab | A combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
| WO2010138421A1 (en) * | 2009-05-27 | 2010-12-02 | Merck Sharp & Dohme Corp. | HEXAHYDROCYCLOPENTYL[f]INDAZOLE REVERSED AMIDES AND DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS |
| WO2011119518A1 (en) * | 2010-03-25 | 2011-09-29 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
| GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
| GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
| SG195309A1 (en) | 2011-06-29 | 2013-12-30 | Astrazeneca Ab | Crystalline form of indazolyl amide derivatives for the treatment glucocorticoid receptor mediated disorders |
| CA2925952A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| CA2925595A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| JP2016535010A (ja) | 2013-10-17 | 2016-11-10 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除性化合物の製造方法 |
| MX2016004940A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Proceso para la preparacion de compuestos plaguicidas. |
| WO2015058021A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| CN105636445B (zh) | 2013-10-17 | 2018-12-07 | 美国陶氏益农公司 | 制备杀虫化合物的方法 |
| EP3057426A4 (en) | 2013-10-17 | 2017-03-29 | Dow AgroSciences LLC | Processes for the preparation of pesticidal compounds |
| KR20170039121A (ko) | 2014-07-31 | 2017-04-10 | 다우 아그로사이언시즈 엘엘씨 | 3-(3-클로로-1h-피라졸-1-일)피리딘의 제조 방법 |
| CN106488909A (zh) | 2014-07-31 | 2017-03-08 | 美国陶氏益农公司 | 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法 |
| JP2017523168A (ja) | 2014-07-31 | 2017-08-17 | ダウ アグロサイエンシィズ エルエルシー | 3−(3−クロロ−1h−ピラゾール−1−イル)ピリジンの製造方法 |
| KR20170042714A (ko) | 2014-08-19 | 2017-04-19 | 다우 아그로사이언시즈 엘엘씨 | 3-(3-클로로-1h-피라졸-1-일)피리딘의 제조 방법 |
| JP2017528469A (ja) | 2014-09-12 | 2017-09-28 | ダウ アグロサイエンシィズ エルエルシー | 3−(3−クロロ−1h−ピラゾール−1−イル)ピリジンの調製方法 |
| FR3026105B1 (fr) * | 2014-09-24 | 2019-04-19 | Greenpharma | Composition contenant au moins un inhibiteur de certaines chimiokines, son procede d'obtention et son utilisation dermocosmetique ou pharmaceutique |
| ES2751640T3 (es) * | 2014-09-26 | 2020-04-01 | Astrazeneca Ab | Compuestos de 1-alquil-6-oxo-1,6-dihidropiridin-3-ilo y uso como moduladores de SGRM |
| HUE048410T2 (hu) | 2015-09-15 | 2020-07-28 | Leo Pharma As | Nem szteroid glükokortikoid receptor modulátorok helyi gyógyszer bejuttatásra |
| WO2017161518A1 (en) | 2016-03-23 | 2017-09-28 | Astrazeneca Ab | New physical form |
| WO2018125817A1 (en) | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| BR112019008372B1 (pt) | 2016-12-29 | 2021-11-09 | Dow Agrosciences Llc | Processo para preparação de compostos pesticidas |
| TW201927769A (zh) * | 2017-12-18 | 2019-07-16 | 德商歌林達有限公司 | 經取代之吡咯啶醯胺ii |
| AU2018387793A1 (en) | 2017-12-18 | 2020-07-30 | Grünenthal GmbH | Substituted pyrrolidine amides I |
| TWI827785B (zh) | 2019-01-11 | 2024-01-01 | 德商歌林達有限公司 | 經取代的吡咯啶醯胺iii |
| WO2020152193A1 (en) | 2019-01-22 | 2020-07-30 | Akribes Biomedical Gmbh | Selective glucocorticoid receptor modifiers for treating impaired skin wound healing |
| WO2020254552A2 (en) | 2019-06-19 | 2020-12-24 | Grünenthal GmbH | Substituted pyrrolidine amides v |
| EP3986885B1 (en) | 2019-06-19 | 2023-05-03 | Grünenthal GmbH | Substituted pyrrolidine amides iv |
| CN114929684B (zh) * | 2019-12-31 | 2023-08-18 | 南京明德新药研发有限公司 | 苯并吡唑类化合物 |
| US12522586B2 (en) | 2020-07-09 | 2026-01-13 | Gruenenthal Gmbh | Substituted pyrrolidine amines and amides VI |
| US20240246985A1 (en) * | 2021-06-28 | 2024-07-25 | Medshine Discovery Inc. | Crystal form of triazolopyridine-substituted indazole compound and preparation method therefor |
| KR102571432B1 (ko) * | 2023-02-08 | 2023-08-29 | 주식회사 에스씨엘테라퓨틱스 | 인다졸릴에스테르 및 아미드 유도체를 포함하는 암 치료용 조성물 |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3992441A (en) * | 1972-12-26 | 1976-11-16 | Pfizer Inc. | Sulfamylbenzoic acids |
| DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| DE3514696A1 (de) | 1985-04-24 | 1986-11-06 | Bayer Ag, 5090 Leverkusen | N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung |
| DE3535167A1 (de) * | 1985-10-02 | 1987-04-09 | Boehringer Mannheim Gmbh | Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3632329A1 (de) | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
| TW224462B (es) | 1992-02-24 | 1994-06-01 | Squibb & Sons Inc | |
| NZ247440A (en) | 1992-05-06 | 1995-04-27 | Squibb & Sons Inc | Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof |
| CA2114981A1 (en) | 1993-02-09 | 1994-08-10 | Kazumi Ogata | Quinolonecarboxylic acid derivatives |
| DE4323916A1 (de) | 1993-07-16 | 1995-01-19 | Basf Ag | Substituierte 2-Phenylpyridine |
| ATE225334T1 (de) | 1993-07-26 | 2002-10-15 | Eisai Co Ltd | Sulfonamide und sulfonsäure-ester mit je einem trizyclischen heteroring |
| GB9504854D0 (en) * | 1994-03-31 | 1995-04-26 | Zeneca Ltd | Nitrogen derivatives |
| US5545669A (en) | 1994-06-02 | 1996-08-13 | Adams; Jerry L. | Anti-inflammatory compounds |
| GB9417532D0 (en) | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
| AU5772296A (en) | 1995-05-19 | 1996-11-29 | Chiroscience Limited | 3,4-disubstituted-phenylsulphonamides and their therapeutic use |
| TW523506B (en) | 1996-12-18 | 2003-03-11 | Ono Pharmaceutical Co | Sulfonamide or carbamide derivatives and drugs containing the same as active ingredients |
| TW542822B (en) | 1997-01-17 | 2003-07-21 | Ajinomoto Kk | Benzamidine derivatives |
| ZA9811898B (en) | 1997-12-29 | 2000-06-28 | Ortho Mcneil Pharm Inc | Anti-Inflammatory Compounds. |
| JP4253126B2 (ja) | 1998-01-29 | 2009-04-08 | アムジェン インコーポレイテッド | Ppar−ガンマ調節剤 |
| DE19856475A1 (de) * | 1998-11-27 | 2000-05-31 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| EP1190710A4 (en) | 1999-05-13 | 2003-04-02 | Shionogi & Co | PREVENTIVE OR THERAPEUTIC MEDICATIONS FOR DIABETES |
| US6569885B1 (en) | 1999-12-23 | 2003-05-27 | Icos Corporation | Cyclic AMP-specific phosphodiesterase inhibitors |
| EP1317425B1 (en) | 2000-09-11 | 2004-11-03 | Pfizer Products Inc. | Resorcinol derivatives |
| FR2815030A1 (fr) | 2000-10-05 | 2002-04-12 | Lipha | Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant et leur utilisation pour la preparation de medicaments |
| US20030109550A1 (en) * | 2001-09-19 | 2003-06-12 | Michael Clare | Substituted indazole compounds for the treatment of inflammation |
| CA2460594A1 (en) * | 2001-10-01 | 2003-04-10 | Taisho Pharmaceutical Co., Ltd. | Mch receptor antagonists |
| BR0214345A (pt) | 2001-11-22 | 2004-09-14 | Ono Pharmaceutical Co | Compostos derivados de piperidin-2-ona e composições farmacêuticas contendo estes compostos como ingrediente ativo |
| EA007099B1 (ru) | 2002-03-13 | 2006-06-30 | Янссен Фармацевтика Н. В. | Сульфонилпроизводные в качестве ингибиторов гистон-деацетилазы |
| US7282591B2 (en) | 2002-04-11 | 2007-10-16 | Merck & Co., Inc. | 1h-benzo{f}indazol-5-yl derivatives as selective glucocorticoid receptor modulators |
| CA2485681C (en) | 2002-05-24 | 2012-10-16 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| NL1021182C2 (nl) * | 2002-07-30 | 2004-02-03 | Xpar Vision B V | Analysesysteem en werkwijze voor het analyseren en controleren van een productieproces voor glasproducten. |
| US20050113450A1 (en) | 2002-08-23 | 2005-05-26 | Atli Thorarensen | Antibacterial agents |
| DE60333371D1 (de) * | 2002-08-29 | 2010-08-26 | Boehringer Ingelheim Pharma | 3-(sulfonamidoethyl)-indol-derivate zur verwendung als glucocorticoid-mimetika bei der behandlung von entzündlichen, allergischen und proliferativen erkrankungen |
| US6894061B2 (en) | 2002-12-04 | 2005-05-17 | Wyeth | Substituted dihydrophenanthridinesulfonamides |
| EP2415760A3 (en) | 2003-02-20 | 2012-02-22 | Encysive Pharmaceuticals, Inc. | CCR-9 antagonists |
| GB0308466D0 (en) | 2003-04-11 | 2003-05-21 | Novartis Ag | Organic compounds |
| US7297709B2 (en) * | 2003-05-22 | 2007-11-20 | Abbott Laboratories | Indazole, benzisoxazole, and benzisothiazole kinase inhibitors |
| US20040235892A1 (en) * | 2003-05-22 | 2004-11-25 | Yujia Dai | Indazole and benzisoxazole kinase inhibitors |
| AU2004247136A1 (en) | 2003-06-10 | 2004-12-23 | Kalypsys, Inc. | Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease |
| US7393873B2 (en) | 2003-07-02 | 2008-07-01 | Merck & Co., Inc. | Arylsulfonamide derivatives |
| OA13344A (en) | 2003-12-19 | 2007-04-13 | Pfizer | Benzenesulfonylamino-pyridin-2-yl derivatives and related compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD-1) for the treatment of diabetes and obesity. |
| JP4829506B2 (ja) | 2004-02-17 | 2011-12-07 | 石原産業株式会社 | チオアミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤 |
| WO2005086904A2 (en) | 2004-03-08 | 2005-09-22 | Amgen Inc. | Therapeutic modulation of ppar (gamma) activity |
| DE102004028862A1 (de) * | 2004-06-15 | 2005-12-29 | Merck Patent Gmbh | 3-Aminoindazole |
| KR20070068432A (ko) * | 2004-10-29 | 2007-06-29 | 아스트라제네카 아베 | 염증 질환의 치료를 위한 글루코코르티코이드 수용체조절제로서의 신규 술폰아미드 유도체 |
| SE0402635D0 (sv) * | 2004-10-29 | 2004-10-29 | Astrazeneca Ab | Chemical compounds |
| EP1869003B1 (en) * | 2005-04-14 | 2013-05-15 | Glaxo Group Limited | Indazoles as glucocorticoid receptor ligands |
| EP1893588A1 (en) | 2005-06-10 | 2008-03-05 | Boehringer Ingelheim International GmbH | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US7888381B2 (en) | 2005-06-14 | 2011-02-15 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof |
| TW200815361A (en) * | 2005-10-20 | 2008-04-01 | Astrazeneca Ab | Chemical compounds |
| GB0522880D0 (en) | 2005-11-09 | 2005-12-21 | Glaxo Group Ltd | Novel compounds |
| WO2007114763A1 (en) | 2006-03-31 | 2007-10-11 | Astrazeneca Ab | Sulphonamide derivates as modulators of the glucocorticoid receptor |
| MX2008013411A (es) * | 2006-04-20 | 2008-11-04 | Glaxo Group Ltd | Nuevos compuestos. |
| BRPI0714811A2 (pt) | 2006-07-14 | 2014-02-18 | Lilly Co Eli | Modulador de receptor de corticóide, seus sais, composições farmacêuticas compreendendo os mesmos e uso dos referidos compostos e sais na fabricação de medicamento |
| GB0620385D0 (en) | 2006-10-13 | 2006-11-22 | Glaxo Group Ltd | Novel compounds |
| GB0620406D0 (en) | 2006-10-13 | 2006-11-22 | Glaxo Group Ltd | Novel compounds |
| US8119681B2 (en) | 2006-10-23 | 2012-02-21 | Merck Sharp & Dohme Corp. | 2-[1-phenyl-5-hydroxy or methoxy-4alpha-methyl-hexahydrocyclopenta [ƒ]indazole-5-YL]ethyl phenyl derivatives as glucocorticoid receptor ligands |
| EP2094692B1 (en) | 2006-11-01 | 2012-11-28 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, ap-1 and/or nf-kappab activity and use thereof |
| WO2008057857A1 (en) | 2006-11-01 | 2008-05-15 | Bristol-Myers Squibb Company | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF |
| TW200829578A (en) | 2006-11-23 | 2008-07-16 | Astrazeneca Ab | Chemical compounds 537 |
| JP2010512331A (ja) | 2006-12-06 | 2010-04-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グルココルチコイド模倣薬、それらの製造方法、医薬組成物、及びこれらの使用 |
| JO2754B1 (en) | 2006-12-21 | 2014-03-15 | استرازينكا ايه بي | Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders |
| WO2008079073A1 (en) | 2006-12-22 | 2008-07-03 | Astrazeneca Ab | Indazolyl sulphonamide derivatives for the treatment of glucocorticoid receptor mediated disorders |
| EP2136634A4 (en) | 2007-04-10 | 2011-07-06 | Boehringer Ingelheim Int | GLUCOCORTICOID MIMETICS, METHOD FOR THE MANUFACTURE THEREOF, PHARMACEUTICAL COMPOSITIONS AND THEIR USE |
| JP2010523691A (ja) | 2007-04-10 | 2010-07-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グルココルチコイドミメティックス、その製造方法、医薬組成物及びその使用 |
| GB0708858D0 (en) | 2007-05-08 | 2007-06-13 | Glaxo Group Ltd | Novel compounds |
| GB0720544D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| GB0720556D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| GB0720546D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| GB0720549D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| GB0720557D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| GB0722211D0 (en) | 2007-11-12 | 2007-12-27 | Glaxo Group Ltd | Novel compounds |
| GB0724254D0 (en) | 2007-12-12 | 2008-01-23 | Glaxo Group Ltd | Novel compounds |
| EP2268630A4 (en) | 2008-02-26 | 2011-03-09 | Merck Sharp & Dohme | HEXAHYDROCYCLOPENTYL [F] INDAZOLCARBOXYL ACID AMIDES AND THEIR DERIVATIVES AS SELECTIVE MODULATORS OF THE GLUCOCORTICOID RECEPTOR |
| WO2009111214A1 (en) | 2008-03-06 | 2009-09-11 | Merck & Co., Inc. | Hexahydrocyclopentyl[f]indazole sulfonamides and derivatives thereof as selective glucocorticoid receptor modulators |
| TWI445705B (zh) * | 2008-05-20 | 2014-07-21 | Astrazeneca Ab | 經苯基及苯并二基取代之吲唑衍生物 |
| WO2010008341A1 (en) * | 2008-07-16 | 2010-01-21 | Astrazeneca Ab | A combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
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| DE602007005387D1 (de) | Ptors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20170728 |