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BR9710350A - Stnfr truncado proteina de liga-Æo de necrose de tumor e polivalente polinucleot¡deo sequ-ncia de cido nucl-ico polinucleot¡deo vetor c-lula hospedeira procardiotica composi-Æo farmac-utica processos para pratar uma doen-a mediada por tnf e para preparar uma composi-Æo farmac-utica uso da prote¡na de liga-Æo de fator de necrose de tumor e kit - Google Patents

Stnfr truncado proteina de liga-Æo de necrose de tumor e polivalente polinucleot¡deo sequ-ncia de cido nucl-ico polinucleot¡deo vetor c-lula hospedeira procardiotica composi-Æo farmac-utica processos para pratar uma doen-a mediada por tnf e para preparar uma composi-Æo farmac-utica uso da prote¡na de liga-Æo de fator de necrose de tumor e kit

Info

Publication number
BR9710350A
BR9710350A BR9710350A BR9710350A BR9710350A BR 9710350 A BR9710350 A BR 9710350A BR 9710350 A BR9710350 A BR 9710350A BR 9710350 A BR9710350 A BR 9710350A BR 9710350 A BR9710350 A BR 9710350A
Authority
BR
Brazil
Prior art keywords
tumor necrosis
pharmaceutical composition
binding protein
procardiotic
stnfr
Prior art date
Application number
BR9710350A
Other languages
English (en)
Inventor
Eric F Fischer
Gary L Kieft
Carl K Edwards Iii
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of BR9710350A publication Critical patent/BR9710350A/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
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    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0306Animal model for genetic diseases
    • A01K2267/0325Animal model for autoimmune diseases
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815Carrier is a synthetic polymer

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  • Molecular Biology (AREA)
  • Biophysics (AREA)
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  • Cell Biology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Environmental Sciences (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
BR9710350A 1996-07-09 1997-07-09 Stnfr truncado proteina de liga-Æo de necrose de tumor e polivalente polinucleot¡deo sequ-ncia de cido nucl-ico polinucleot¡deo vetor c-lula hospedeira procardiotica composi-Æo farmac-utica processos para pratar uma doen-a mediada por tnf e para preparar uma composi-Æo farmac-utica uso da prote¡na de liga-Æo de fator de necrose de tumor e kit BR9710350A (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US2144396P 1996-07-09 1996-07-09
US3253496P 1996-12-06 1996-12-06
US3773797P 1997-01-23 1997-01-23
US3931497P 1997-02-07 1997-02-07
US3979297P 1997-03-04 1997-03-04
PCT/US1997/012244 WO1998001555A2 (en) 1996-07-09 1997-07-09 Truncated soluble tumor necrosis factor type-i and type-ii receptors

Publications (1)

Publication Number Publication Date
BR9710350A true BR9710350A (pt) 1999-08-17

Family

ID=27533913

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710350A BR9710350A (pt) 1996-07-09 1997-07-09 Stnfr truncado proteina de liga-Æo de necrose de tumor e polivalente polinucleot¡deo sequ-ncia de cido nucl-ico polinucleot¡deo vetor c-lula hospedeira procardiotica composi-Æo farmac-utica processos para pratar uma doen-a mediada por tnf e para preparar uma composi-Æo farmac-utica uso da prote¡na de liga-Æo de fator de necrose de tumor e kit

Country Status (22)

Country Link
US (2) US6989147B2 (pt)
EP (1) EP0914431B1 (pt)
JP (2) JP2002514048A (pt)
KR (1) KR20000023695A (pt)
AT (1) ATE364695T1 (pt)
AU (2) AU3601397A (pt)
BG (1) BG64910B1 (pt)
BR (1) BR9710350A (pt)
CA (1) CA2259156C (pt)
CZ (1) CZ296835B6 (pt)
DE (1) DE69737814T2 (pt)
EA (1) EA003900B1 (pt)
ES (1) ES2288304T3 (pt)
IL (1) IL127874A0 (pt)
NO (1) NO990086L (pt)
NZ (1) NZ333647A (pt)
PL (1) PL189309B1 (pt)
SK (1) SK1599A3 (pt)
TR (1) TR199700610A3 (pt)
TW (1) TW555765B (pt)
WO (1) WO1998001555A2 (pt)
YU (1) YU299A (pt)

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WO2009009186A2 (en) * 2007-04-13 2009-01-15 The Regents Of The University Of California Receptors useful for gas phase chemical sensing
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ATE364695T1 (de) 2007-07-15
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