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AR008727A1 - COMPOSICIONES Y PROTEINAS DE FUSIoN QUE COMPRENDEN UN POLIPEPTIDO QUE COMPRENDE UNA PORCION INMUNOGENICA DE UNA PROTEINA DE PROSTATA O SU VARIANTE, Y USOS DE LAS MISMAS PARA PREPARAR UN MEDICAMENTO - Google Patents

COMPOSICIONES Y PROTEINAS DE FUSIoN QUE COMPRENDEN UN POLIPEPTIDO QUE COMPRENDE UNA PORCION INMUNOGENICA DE UNA PROTEINA DE PROSTATA O SU VARIANTE, Y USOS DE LAS MISMAS PARA PREPARAR UN MEDICAMENTO

Info

Publication number
AR008727A1
AR008727A1 ARP980100838A ARP980100838A AR008727A1 AR 008727 A1 AR008727 A1 AR 008727A1 AR P980100838 A ARP980100838 A AR P980100838A AR P980100838 A ARP980100838 A AR P980100838A AR 008727 A1 AR008727 A1 AR 008727A1
Authority
AR
Argentina
Prior art keywords
variant
compositions
prepare
immunogenic portion
medicinal product
Prior art date
Application number
ARP980100838A
Other languages
English (en)
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of AR008727A1 publication Critical patent/AR008727A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un polipéptido que comprende una porcion inmunogénica de una proteína de prostata o su variante, donde dicha proteína comprende a una secuencia deaminoácido codificada por una molécula de ADN que tiene una secuencia seleccionada delgrup o formado por las secuencias de nucleotido enumeradas enlos NRs de Sec:2, 3, 8-29, 41-45, 47-52, 45-65, 70, 73, 74, 79, 81, 90, 92, 93, 97, 103, 104, 107, 109-111, 115-160, 171, 173-175 y 177, los complementos dedichas secuencias de nucleotidoy las variantes de dichas secuencias de nucleotido, molécula de ADN, vector de expresion, célula huésped, composicionfarmacéutica, vacuna, uso de dichas composiciones y vacunas para preparar medicamentos y proteína de fusion.
ARP980100838A 1997-02-25 1998-02-25 COMPOSICIONES Y PROTEINAS DE FUSIoN QUE COMPRENDEN UN POLIPEPTIDO QUE COMPRENDE UNA PORCION INMUNOGENICA DE UNA PROTEINA DE PROSTATA O SU VARIANTE, Y USOS DE LAS MISMAS PARA PREPARAR UN MEDICAMENTO AR008727A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80609997A 1997-02-25 1997-02-25
US90480497A 1997-08-01 1997-08-01
US09/020,956 US6261562B1 (en) 1997-02-25 1998-02-09 Compounds for immunotherapy of prostate cancer and methods for their use

Publications (1)

Publication Number Publication Date
AR008727A1 true AR008727A1 (es) 2000-02-09

Family

ID=27122845

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP980100838A AR008727A1 (es) 1997-02-25 1998-02-25 COMPOSICIONES Y PROTEINAS DE FUSIoN QUE COMPRENDEN UN POLIPEPTIDO QUE COMPRENDE UNA PORCION INMUNOGENICA DE UNA PROTEINA DE PROSTATA O SU VARIANTE, Y USOS DE LAS MISMAS PARA PREPARAR UN MEDICAMENTO
ARP070103521A AR062300A2 (es) 1997-02-25 2007-08-09 Polipeptido que comprende una porcion inmunogenica de una proteina de prostata o su variante, molecula de adn, vector de expresion, celula huesped composicion farmaceutica, vacuna uso de dichas composiciones y vacunas para preparar medicamentos y proteina de fusion

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP070103521A AR062300A2 (es) 1997-02-25 2007-08-09 Polipeptido que comprende una porcion inmunogenica de una proteina de prostata o su variante, molecula de adn, vector de expresion, celula huesped composicion farmaceutica, vacuna uso de dichas composiciones y vacunas para preparar medicamentos y proteina de fusion

Country Status (8)

Country Link
US (1) US6261562B1 (es)
EP (2) EP2143731A1 (es)
KR (1) KR100572817B1 (es)
AR (2) AR008727A1 (es)
CA (1) CA2742641A1 (es)
CO (1) CO4850588A1 (es)
SA (1) SA98190265B1 (es)
TW (1) TW581808B (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7202342B1 (en) 1999-11-12 2007-04-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US20030185830A1 (en) * 1997-02-25 2003-10-02 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US20060024301A1 (en) * 1997-02-25 2006-02-02 Corixa Corporation Prostate-specific polypeptides and fusion polypeptides thereof
US7517952B1 (en) 1997-02-25 2009-04-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6657056B2 (en) * 1997-02-25 2003-12-02 Corixa Corporation Compounds for immunotherapy of prostate cancer and methods for their use
AU7019498A (en) * 1997-04-10 1998-10-30 Diagnocure Inc. Pca3, pca3 genes, and methods of use
US20020106688A1 (en) * 1997-08-05 2002-08-08 Moncef Jenboubi Identification of gene sequences and gene products and their specific function and relationship to pathologies in a mammal
US6623923B1 (en) * 1998-12-23 2003-09-23 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
US7063959B1 (en) * 1998-12-30 2006-06-20 Beth Israel Deaconess Medical Center, Inc. Compositions of the SOC/CRAC calcium channel protein family
AU5416700A (en) * 1999-05-20 2000-12-12 Fahri Saatcioglu Differentially expressed genes in prostate cancer
US7368545B1 (en) 1999-09-29 2008-05-06 Diagnocure Inc. PCA3 messenger RNA species in benign and malignant prostate tissues
US7611892B2 (en) * 2000-03-24 2009-11-03 President And Fellows Of Harvard College Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US8489176B1 (en) 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8909325B2 (en) 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8565860B2 (en) 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
WO2005119025A2 (en) 2004-06-01 2005-12-15 Spectrum Dynamics Llc Radioactive-emission-measurement optimization to specific body structures
US8036731B2 (en) 2001-01-22 2011-10-11 Spectrum Dynamics Llc Ingestible pill for diagnosing a gastrointestinal tract
US20020123081A1 (en) * 2000-09-28 2002-09-05 Jennifer Richardson Methods of use of alpha-methylacyl-CoA racemase in hormone refractory and metastatic prostate cancers
US7048931B1 (en) * 2000-11-09 2006-05-23 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
EP1359845B1 (en) 2001-01-22 2012-11-14 Spectrum Dynamics LLC Ingestible device
WO2002089747A2 (en) 2001-05-09 2002-11-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6897024B2 (en) * 2001-05-31 2005-05-24 Stichting Katholieke Universiteit More Particularly The University Medical Centre Nijmegen Nucleic acid molecules comprising the promoter for PCA3, and uses thereof
US20040116807A1 (en) * 2002-10-17 2004-06-17 Roni Amrami Blood vessels wall imaging catheter
EP1573495B1 (en) * 2002-11-04 2009-11-04 Spectrum Dynamics LLC Apparatus and methods for imaging and attenuation correction
US20050282170A1 (en) 2003-02-07 2005-12-22 Diagnocure Inc. Method to detect prostate cancer in a sample
JP2007501616A (ja) * 2003-08-07 2007-02-01 カイロン コーポレイション 抗癌治療のための標的としてのトレホイル因子３（ｔｆｆ３）
WO2006075333A2 (en) 2005-01-13 2006-07-20 Spectrum Dynamics Llc Multi-dimensional image reconstruction and analysis for expert-system diagnosis
CN1981210A (zh) 2004-01-13 2007-06-13 光谱动力学有限责任公司 多维图像重构
US8586932B2 (en) 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
US9470801B2 (en) 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
WO2006054296A2 (en) * 2004-11-17 2006-05-26 Spectrum Dynamics Llc Methods of detecting prostate cancer
WO2006051531A2 (en) 2004-11-09 2006-05-18 Spectrum Dynamics Llc Radioimaging
US9040016B2 (en) 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
WO2007010534A2 (en) 2005-07-19 2007-01-25 Spectrum Dynamics Llc Imaging protocols
US8280124B2 (en) 2004-06-01 2012-10-02 Spectrum Dynamics Llc Methods of view selection for radioactive emission measurements
US8423125B2 (en) 2004-11-09 2013-04-16 Spectrum Dynamics Llc Radioimaging
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
WO2008059489A2 (en) 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
CA2491067A1 (en) 2004-12-24 2006-06-24 Stichting Katholieke Universiteit Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
EP1908011B1 (en) 2005-07-19 2013-09-04 Spectrum Dynamics LLC Reconstruction stabilizer and active vision
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
US7705316B2 (en) * 2005-11-09 2010-04-27 Spectrum Dynamics Llc Dynamic SPECT camera
US8204500B2 (en) 2005-12-28 2012-06-19 Starhome Gmbh Optimal voicemail deposit for roaming cellular telephony
US8894974B2 (en) 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
WO2008075362A2 (en) 2006-12-20 2008-06-26 Spectrum Dynamics Llc A method, a system, and an apparatus for using and processing multidimensional data
US8521253B2 (en) 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
DK2430190T3 (en) * 2009-05-12 2019-02-18 Koninklijke Philips Nv PHOSPHODIESTERASE-4D7 AS MARKER FOR DEATH, HORMON-SENSITIVE PROSTATANCES
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
RU2461916C1 (ru) * 2011-01-12 2012-09-20 Государственное образовательное учреждение высшего профессионального образования Томский государственный университет систем управления и радиоэлектроники (ТУСУР) Полупроводниковый светоизлучающий прибор

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2095698A (en) 1937-10-12 Ox yoke model
US4489710A (en) 1981-06-23 1984-12-25 Xoma Corporation Composition and method for transplantation therapy
US4429008B1 (en) 1981-12-10 1995-05-16 Univ California Thiol reactive liposomes
US4769330A (en) 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4671958A (en) 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
JPS59116229A (ja) 1982-12-24 1984-07-05 Teijin Ltd 細胞毒性複合体を活性成分とする癌治療用剤およびその製造法
US4673562A (en) 1983-08-19 1987-06-16 The Children's Medical Center Corporation Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents
US4873088A (en) 1983-09-06 1989-10-10 Liposome Technology, Inc. Liposome drug delivery method and composition
US4625014A (en) 1984-07-10 1986-11-25 Dana-Farber Cancer Institute, Inc. Cell-delivery agent
US4542225A (en) 1984-08-29 1985-09-17 Dana-Farber Cancer Institute, Inc. Acid-cleavable compound
US4638045A (en) 1985-02-19 1987-01-20 Massachusetts Institute Of Technology Non-peptide polyamino acid bioerodible polymers
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
GB8508845D0 (en) 1985-04-04 1985-05-09 Hoffmann La Roche Vaccinia dna
US4777127A (en) 1985-09-30 1988-10-11 Labsystems Oy Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4699784A (en) 1986-02-25 1987-10-13 Center For Molecular Medicine & Immunology Tumoricidal methotrexate-antibody conjugate
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
GB8702816D0 (en) 1987-02-07 1987-03-11 Al Sumidaie A M K Obtaining retrovirus-containing fraction
US4735792A (en) 1987-04-28 1988-04-05 The United States Of America As Represented By The United States Department Of Energy Radioiodinated maleimides and use as agents for radiolabeling antibodies
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
WO1989001973A2 (en) 1987-09-02 1989-03-09 Applied Biotechnology, Inc. Recombinant pox virus for immunization against tumor-associated antigens
US5041289A (en) 1987-11-13 1991-08-20 Becton Dickinson And Company Method of purging residual tumor cells in vitro with lymphokine activated cytotoxic cells
JPH04505547A (ja) 1988-01-04 1992-10-01 イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー 細胞混合物から特定の細胞を単離するための多段アフィニティー法
AP129A (en) 1988-06-03 1991-04-17 Smithkline Biologicals S A Expression of retrovirus gag protein eukaryotic cells
US5215926A (en) 1988-06-03 1993-06-01 Cellpro, Inc. Procedure for designing efficient affinity cell separation processes
DK0737750T3 (da) 1989-03-21 2003-09-01 Vical Inc Ekspression af exogene polynucleotidsekvenser i vertebrater
EP0845537A1 (en) 1989-08-18 1998-06-03 Chiron Corporation Recombinant retroviruses delivering vector constructs to target cells
WO1991016116A1 (en) 1990-04-23 1991-10-31 Cellpro Incorporated Immunoselection device and method
WO1992007243A1 (en) 1990-10-18 1992-04-30 Cellpro, Incorporated An apparatus and method for separating particles using a pliable vessel
US5851764A (en) 1990-10-25 1998-12-22 The Trustees Of Columbia University In The City Of New York Human prostate tumor inducing gene-1 and uses thereof
US5240856A (en) 1991-10-23 1993-08-31 Cellpro Incorporated Apparatus for cell separation
WO1993014753A1 (en) 1992-01-27 1993-08-05 The Board Of Trustees Of The Leland Stanford Junior University Histamine derivatives and methods for their use
US5428011A (en) 1992-06-16 1995-06-27 Procyon Biopharma, Inc. Pharmaceutical preparations for inhibiting tumours associated with prostate adenocarcinoma
US5786148A (en) 1996-11-05 1998-07-28 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a novel prostate-specific kallikrein
EP1757694A3 (en) 1992-11-05 2008-02-27 Sloan Kettering Institute For Cancer Research Prostate-specific membrane antigen
US5359681A (en) 1993-01-11 1994-10-25 University Of Washington Fiber optic sensor and methods and apparatus relating thereto
JPH09504000A (ja) 1993-08-11 1997-04-22 ジェナー テクノロジーズ 前立腺癌ワクチン
EP0652014A1 (en) 1993-11-10 1995-05-10 National Institute Of Immunology Treatment of prostatic hypertrophy
WO1995014772A1 (en) 1993-11-12 1995-06-01 Kenichi Matsubara Gene signature
JPH10500294A (ja) 1994-05-10 1998-01-13 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ 組換え型ｈｋ２ポリペプチド
KR19990087802A (ko) 1996-03-15 1999-12-27 길리스 스티브 전립선암의 면역치료 및 면역진단을 위한 화합물 및 방법
US5955306A (en) 1996-09-17 1999-09-21 Millenium Pharmaceuticals, Inc. Genes encoding proteins that interact with the tub protein
WO1998017687A2 (en) 1996-10-25 1998-04-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
CA2278118A1 (en) 1997-01-21 1998-07-23 Human Genome Sciences, Inc. Polynucleotides and polypeptides encoding receptors
ATE302414T1 (de) 1997-02-25 2005-09-15 Corixa Corp Verbindungen zur immundiagnose von prostatakrebs und deren verwendung
HUP0002095A3 (en) 1997-02-25 2002-02-28 Corixa Corp Seattle Compounds for immunotherapy of prostate cancer and methods for their use
US6020478A (en) 1997-02-28 2000-02-01 Incyte Pharmaceuticals, Inc. Human tumor-associated antigen
CA2284131A1 (en) 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins
WO1998045435A2 (en) 1997-04-10 1998-10-15 Genetics Institute, Inc. SECRETED EXPRESSED SEQUENCE TAGS (sESTs)
US6130043A (en) 1997-05-02 2000-10-10 Abbott Laboratories Reagents and methods useful for detecting diseases of the prostate
AU8555198A (en) 1997-08-01 1999-02-22 Genset 5' ests for secreted proteins expressed in prostate
US6222029B1 (en) 1997-08-01 2001-04-24 Genset 5′ ESTs for secreted proteins expressed in brain
PT1000146E (pt) 1997-08-01 2006-10-31 Serono Genetics Inst Sa Ests 5' para proteinas secretadas sem especificidade tecidular
WO1999031236A2 (en) 1997-12-17 1999-06-24 Genset EXTENDED cDNAs FOR SECRETED PROTEINS
JP2001523453A (ja) 1997-11-13 2001-11-27 ジェンセット 分泌タンパク質の伸長ｃＤＮＡ
DE19805633A1 (de) 1998-02-12 1999-08-19 Basf Ag Neue Serinprotease aus der Prostata

Also Published As

Publication number Publication date
AR062300A2 (es) 2008-10-29
US6261562B1 (en) 2001-07-17
EP2143731A1 (en) 2010-01-13
CO4850588A1 (es) 1999-10-26
KR100572817B1 (ko) 2006-04-24
EP2298877B1 (en) 2014-09-24
EP2298877A1 (en) 2011-03-23
SA98190265B1 (ar) 2006-11-12
TW581808B (en) 2004-04-01
KR20000075699A (ko) 2000-12-26
CA2742641A1 (en) 1998-08-27

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