BR9703886A - Piridinas bicíclicas fusionadas - Google Patents
Piridinas bicíclicas fusionadasInfo
- Publication number
- BR9703886A BR9703886A BR9703886A BR9703886A BR9703886A BR 9703886 A BR9703886 A BR 9703886A BR 9703886 A BR9703886 A BR 9703886A BR 9703886 A BR9703886 A BR 9703886A BR 9703886 A BR9703886 A BR 9703886A
- Authority
- BR
- Brazil
- Prior art keywords
- fused bicyclic
- pyridines
- bicyclic pyridines
- fused
- bicyclic
- Prior art date
Links
- -1 bicyclic pyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19627430A DE19627430A1 (de) | 1996-07-08 | 1996-07-08 | Bicyclisch kondensierte Pyridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9703886A true BR9703886A (pt) | 1998-11-03 |
Family
ID=7799218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9703886A BR9703886A (pt) | 1996-07-08 | 1997-07-08 | Piridinas bicíclicas fusionadas |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6063788A (pt) |
| EP (1) | EP0825185A1 (pt) |
| JP (1) | JPH1067751A (pt) |
| KR (1) | KR980009247A (pt) |
| CN (1) | CN1172803A (pt) |
| AR (1) | AR007716A1 (pt) |
| AU (1) | AU722365B2 (pt) |
| BG (1) | BG61972B1 (pt) |
| BR (1) | BR9703886A (pt) |
| CA (1) | CA2209609A1 (pt) |
| CO (1) | CO4870759A1 (pt) |
| CZ (1) | CZ214797A3 (pt) |
| DE (1) | DE19627430A1 (pt) |
| EE (1) | EE9700151A (pt) |
| HN (1) | HN1997000082A (pt) |
| HR (1) | HRP970331A2 (pt) |
| HU (1) | HUP9701158A1 (pt) |
| ID (1) | ID17659A (pt) |
| IL (1) | IL121235A0 (pt) |
| MA (1) | MA24261A1 (pt) |
| NO (1) | NO308738B1 (pt) |
| NZ (1) | NZ328260A (pt) |
| PE (1) | PE87798A1 (pt) |
| PL (1) | PL320954A1 (pt) |
| SG (1) | SG46782A1 (pt) |
| SK (1) | SK92697A3 (pt) |
| TN (1) | TNSN97116A1 (pt) |
| TR (1) | TR199700583A2 (pt) |
| YU (1) | YU28897A (pt) |
| ZA (1) | ZA976021B (pt) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6642268B2 (en) | 1994-09-13 | 2003-11-04 | G.D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors |
| US6268392B1 (en) | 1994-09-13 | 2001-07-31 | G. D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors |
| US6262277B1 (en) | 1994-09-13 | 2001-07-17 | G.D. Searle And Company | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
| KR20010099937A (ko) | 1998-12-23 | 2001-11-09 | 윌리암스 로저 에이 | 심혈관 징후용 콜레스테릴 에스테르 전달 단백질 억제제및 피브르산 유도체의 조합물 |
| US6462091B1 (en) | 1998-12-23 | 2002-10-08 | G.D. Searle & Co. | Combinations of cholesteryl ester transfer protein inhibitors and HMG coA reductase inhibitors for cardiovascular indications |
| EP1340510A1 (en) | 1998-12-23 | 2003-09-03 | G.D. Searle LLC. | Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications |
| DE69908643T2 (de) | 1998-12-23 | 2004-05-13 | G.D. Searle Llc, Chicago | Kombinationen von cholesteryl ester transfer protein inhibitoren und nicotinsäure derivaten für kardiovaskuläre indikationen |
| ATE228012T1 (de) | 1998-12-23 | 2002-12-15 | Searle Llc | Kombinationen von ileumgallensäuretransports inhibitoren und gallensäure sequestriermitteln für kardiovaskuläre indikationen |
| EA005815B1 (ru) | 1998-12-23 | 2005-06-30 | Джи.Ди.Сирл Ллс | Комбинация ингибиторов транспорта желчных кислот в подвздошной кишке и ингибиторов белка, переносящего эфиры холестерина, для сердечно-сосудистых показаний |
| KR20010102964A (ko) | 1998-12-23 | 2001-11-17 | 윌리암스 로저 에이 | 심장혈관 징후를 위한 회장 담즙산 수송 억제인자 및피브린산 유도체의 조합물 |
| US6677341B2 (en) | 1999-09-23 | 2004-01-13 | Pharmacia Corporation | (R)-Chiral halogenated substituted heteroaryl benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| US20010018446A1 (en) | 1999-09-23 | 2001-08-30 | G.D. Searle & Co. | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity |
| US6924313B1 (en) | 1999-09-23 | 2005-08-02 | Pfizer Inc. | Substituted tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity |
| US6586434B2 (en) | 2000-03-10 | 2003-07-01 | G.D. Searle, Llc | Method for the preparation of tetrahydrobenzothiepines |
| US20040219619A1 (en) * | 2000-07-21 | 2004-11-04 | Ester Fernandez-Salas | Methods of identifying compounds that alter toxin persistence and/or protease activity |
| US6958328B2 (en) * | 2001-04-18 | 2005-10-25 | Ortho-Mcneil Pharmaceutical, Inc | Arylindenopyridines and related therapeutic and prophylactic methods |
| US20050239782A1 (en) * | 2001-04-18 | 2005-10-27 | Heintzelman Geoffrey R | Arylindenopyridines and related therapeutic and prophylactic methods |
| US6903109B2 (en) | 2001-04-18 | 2005-06-07 | Ortho-Muniel Pharmaceutical, Inc. | Arylindenopyridines and related therapeutic and prophylactic methods |
| CA2450957A1 (en) | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions of dispersions of drugs and neutral polymers |
| WO2003000238A1 (en) | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions of adsorbates of amorphous drug |
| EP1448546A4 (en) | 2001-11-02 | 2005-02-02 | Searle Llc | MONO- AND DI-FLUORINATED BENZOTHIEPINE COMPOUNDS AS INHIBITORS OF TRANSPORT OF ACIDICALLY DEPENDENT SODIUM ACILIC (ASBT) BILIARY ACIDS AND TAUROCHOLATE RECOVERY |
| JP2005521653A (ja) | 2002-01-17 | 2005-07-21 | ファルマシア コーポレイション | 先端ナトリウム同時依存性胆汁酸輸送（ａｓｂｔ）およびタウロコール酸塩取込みの阻害剤としての新規アルキル／アリールヒドロキシまたはケトチエピン化合物 |
| BR0307344A (pt) | 2002-02-01 | 2004-12-14 | Pfizer Prod Inc | Composições farmacêuticas de dispersões amorfas de fármacos e materiais formadores de microfase lipofìlica |
| US20040127510A1 (en) * | 2002-04-16 | 2004-07-01 | Heintzelman Geoffrey R. | Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods |
| BRPI0413277A (pt) * | 2003-08-04 | 2006-10-10 | Pfizer Prod Inc | composições farmacêuticas de adsorvatos de medicamentos amorfos e materiais que formam microfases lipofìlicas |
| CL2004001884A1 (es) | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
| CN1886124A (zh) | 2003-09-26 | 2006-12-27 | 日本烟草产业株式会社 | 抑制残余脂蛋白产生的方法 |
| US7749992B2 (en) | 2003-10-08 | 2010-07-06 | Eli Lilly And Company | Compounds and methods for treating dislipidemia |
| ATE402180T1 (de) | 2004-03-26 | 2008-08-15 | Lilly Co Eli | Verbindungen zur behandlung von dyslipidemie |
| EP1828137B1 (de) * | 2004-12-18 | 2012-04-25 | Bayer Pharma Aktiengesellschaft | 4-cycloalkyl-substituierte tetrahydrochinolinderivate und deren verwendung als medikamente |
| WO2006082518A1 (en) | 2005-02-03 | 2006-08-10 | Pfizer Products Inc. | Pharmaceutical compositions with enhanced performance |
| WO2007048027A2 (en) | 2005-10-21 | 2007-04-26 | Novartis Ag | Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent |
| DE102006012548A1 (de) * | 2006-03-18 | 2007-09-20 | Bayer Healthcare Ag | Substituierte Chromanol-Derivate und ihre Verwendung |
| PA8801401A1 (es) * | 2007-10-25 | 2009-05-15 | Janssen Pharmaceutica Nv | Arilindenopirimidinas y su uso como adenosina a2a |
| US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5169857A (en) * | 1988-01-20 | 1992-12-08 | Bayer Aktiengesellschaft | 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis |
| GB8626344D0 (en) * | 1986-11-04 | 1986-12-03 | Zyma Sa | Bicyclic compounds |
| NO177005C (no) * | 1988-01-20 | 1995-07-05 | Bayer Ag | Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen |
| IE892088L (en) * | 1988-07-12 | 1990-01-12 | William Henry Deryk Morris | Quinoline derivatives, their production and use |
| NZ237097A (en) * | 1990-02-26 | 1993-12-23 | Squibb & Sons Inc | Pyridine derivatives substituted in the 3-position by a phosphinic moiety. |
| JPH059179A (ja) * | 1990-09-27 | 1993-01-19 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及びａｃａｔ阻害剤 |
-
1996
- 1996-07-08 DE DE19627430A patent/DE19627430A1/de not_active Withdrawn
-
1997
- 1997-06-16 HN HN1997000082A patent/HN1997000082A/es unknown
- 1997-06-17 HR HR19627430.3A patent/HRP970331A2/hr not_active Application Discontinuation
- 1997-06-18 SG SG1997002082A patent/SG46782A1/en unknown
- 1997-06-25 EP EP97110360A patent/EP0825185A1/de not_active Withdrawn
- 1997-06-27 US US08/883,067 patent/US6063788A/en not_active Expired - Fee Related
- 1997-07-02 AR ARP970102972A patent/AR007716A1/es not_active Application Discontinuation
- 1997-07-03 AU AU28448/97A patent/AU722365B2/en not_active Ceased
- 1997-07-04 BG BG101746A patent/BG61972B1/bg unknown
- 1997-07-04 CA CA002209609A patent/CA2209609A1/en not_active Abandoned
- 1997-07-04 PL PL97320954A patent/PL320954A1/xx unknown
- 1997-07-04 IL IL12123597A patent/IL121235A0/xx unknown
- 1997-07-04 NZ NZ328260A patent/NZ328260A/en unknown
- 1997-07-04 TR TR97/00583A patent/TR199700583A2/xx unknown
- 1997-07-04 ID IDP972332A patent/ID17659A/id unknown
- 1997-07-07 TN TNTNSN97116A patent/TNSN97116A1/fr unknown
- 1997-07-07 NO NO973144A patent/NO308738B1/no not_active IP Right Cessation
- 1997-07-07 CO CO97037764A patent/CO4870759A1/es unknown
- 1997-07-07 JP JP9195235A patent/JPH1067751A/ja active Pending
- 1997-07-07 CZ CZ972147A patent/CZ214797A3/cs unknown
- 1997-07-07 SK SK926-97A patent/SK92697A3/sk unknown
- 1997-07-07 ZA ZA9706021A patent/ZA976021B/xx unknown
- 1997-07-07 HU HU9701158A patent/HUP9701158A1/hu unknown
- 1997-07-07 KR KR1019970031342A patent/KR980009247A/ko not_active Withdrawn
- 1997-07-07 PE PE1997000581A patent/PE87798A1/es not_active Application Discontinuation
- 1997-07-07 MA MA24705A patent/MA24261A1/fr unknown
- 1997-07-08 CN CN97114558A patent/CN1172803A/zh active Pending
- 1997-07-08 YU YU28897A patent/YU28897A/sh unknown
- 1997-07-08 EE EE9700151A patent/EE9700151A/xx unknown
- 1997-07-08 BR BR9703886A patent/BR9703886A/pt active Search and Examination
Also Published As
| Publication number | Publication date |
|---|---|
| AU722365B2 (en) | 2000-08-03 |
| EE9700151A (et) | 1998-02-16 |
| IL121235A0 (en) | 1998-01-04 |
| KR980009247A (ko) | 1998-04-30 |
| CN1172803A (zh) | 1998-02-11 |
| CZ214797A3 (cs) | 1998-01-14 |
| NO973144D0 (no) | 1997-07-07 |
| TNSN97116A1 (fr) | 2005-03-15 |
| BG101746A (en) | 1998-03-31 |
| DE19627430A1 (de) | 1998-01-15 |
| SG46782A1 (en) | 1998-02-20 |
| ID17659A (id) | 1998-01-15 |
| HUP9701158A1 (hu) | 1999-09-28 |
| MA24261A1 (fr) | 1998-04-01 |
| PE87798A1 (es) | 1999-02-13 |
| AU2844897A (en) | 1998-01-15 |
| NZ328260A (en) | 1998-09-24 |
| SK92697A3 (en) | 1998-02-04 |
| HU9701158D0 (en) | 1997-09-29 |
| TR199700583A2 (xx) | 1998-01-21 |
| EP0825185A1 (de) | 1998-02-25 |
| NO973144L (no) | 1998-01-09 |
| PL320954A1 (en) | 1998-01-19 |
| NO308738B1 (no) | 2000-10-23 |
| YU28897A (sh) | 2000-03-21 |
| BG61972B1 (bg) | 1998-11-30 |
| US6063788A (en) | 2000-05-16 |
| HN1997000082A (es) | 1997-12-26 |
| CO4870759A1 (es) | 1999-12-27 |
| CA2209609A1 (en) | 1998-01-08 |
| JPH1067751A (ja) | 1998-03-10 |
| HRP970331A2 (en) | 1998-08-31 |
| AR007716A1 (es) | 1999-11-10 |
| ZA976021B (en) | 1998-02-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB34 | Technical and formal requirements: requirement - article 34 of industrial property law | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |