|
ATE294793T1
(de)
|
1999-01-15 |
2005-05-15 |
Altana Pharma Ag |
Phenantrhridin-n-oxides mit pde-iv hemmender wirkung
|
|
WO2000042017A1
(en)
*
|
1999-01-15 |
2000-07-20 |
Byk Gulden Lomberg Chemische Fabrik Gmbh |
Phenanthridine-n-oxides with pde-iv inhibiting activity
|
|
SK287231B6
(sk)
|
1999-08-21 |
2010-04-07 |
Nycomed Gmbh |
Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora
|
|
US6953774B2
(en)
|
2000-08-11 |
2005-10-11 |
Applied Research Systems Ars Holding N.V. |
Methods of inducing ovulation
|
|
CZ20031902A3
(cs)
|
2001-01-31 |
2004-07-14 |
Pfizer Products Inc. |
Etherové deriváty užitečné jako inhibitory isozymů PDE4
|
|
OA12542A
(en)
|
2001-01-31 |
2006-06-05 |
Pfizer Prod Inc |
Thiazolyl-, oxazolyl-, pyrrolyl-, and imidazolyl-acid amide derivatives useful as inhibitors of PDE4isozymes.
|
|
US7250518B2
(en)
|
2001-01-31 |
2007-07-31 |
Pfizer Inc. |
Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
|
|
NZ526453A
(en)
|
2001-01-31 |
2005-01-28 |
Pfizer Prod Inc |
Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes
|
|
CN1537018A
(zh)
*
|
2001-05-23 |
2004-10-13 |
田边制药株式会社 |
一种用于软骨疾病再生治疗的组合物
|
|
EP1435944B1
(en)
*
|
2001-10-16 |
2009-09-30 |
Memory Pharmaceutical Corporation |
4(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes
|
|
AR037517A1
(es)
*
|
2001-11-05 |
2004-11-17 |
Novartis Ag |
Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
|
|
DK1463493T3
(da)
|
2001-12-14 |
2008-02-04 |
Serono Lab |
Fremgangsmåder til at inducere æglösning ved anvendelse af en ikke polypeptid-cAMP-niveaumodulator
|
|
BR0315705A
(pt)
|
2002-11-19 |
2005-09-06 |
Memory Pharm Corp |
Inibidores de fosfodiesterase-4
|
|
GB0229281D0
(en)
*
|
2002-12-16 |
2003-01-22 |
Novartis Ag |
Organic compounds
|
|
WO2004087211A2
(en)
|
2003-04-01 |
2004-10-14 |
Applied Research Systems Ars Holding N.V. |
Inhibitors of phosphodiesterases in infertility
|
|
AU2004232958A1
(en)
*
|
2003-04-16 |
2004-11-04 |
F.-Hoffmann La-Roche Inc. |
4 - (3,4 - disubstituted phenyl) - pyrrolidin-2-one compounds as phosphodiesterase 4 inhibitors
|
|
AU2004232973A1
(en)
*
|
2003-04-18 |
2004-11-04 |
Memory Pharmaceuticals Corporation |
Pyrazole derivatives as phosphodiesterase 4 inhibitors
|
|
AR044519A1
(es)
|
2003-05-02 |
2005-09-14 |
Novartis Ag |
Derivados de piridin-tiazol amina y de pirimidin-tiazol amina
|
|
MY141255A
(en)
|
2003-12-11 |
2010-03-31 |
Memory Pharm Corp |
Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
|
|
GB0401334D0
(en)
|
2004-01-21 |
2004-02-25 |
Novartis Ag |
Organic compounds
|
|
US20090042951A1
(en)
*
|
2004-02-20 |
2009-02-12 |
Robert Danziger |
Blood Pressure Reduction in Salt-Sensitive Hypertension
|
|
GB0411056D0
(en)
|
2004-05-18 |
2004-06-23 |
Novartis Ag |
Organic compounds
|
|
EP1758873A1
(en)
*
|
2004-06-22 |
2007-03-07 |
Rigel Pharmaceuticals, Inc. |
Ubiquitin ligase inhibitors
|
|
WO2006031959A1
(en)
*
|
2004-09-14 |
2006-03-23 |
Novartis Ag |
Process for the preparation of 6, 8-substituted `1, 7 naphthpyridin derivatives by reacting the 8-halo-`1, 7 naphthpyridin-derivate with an organic boronic acid derivatives and intermadiates of this process
|
|
CN101166733A
(zh)
|
2004-10-15 |
2008-04-23 |
记忆药物公司 |
作为磷酸二酯酶4抑制剂的吡唑衍生物
|
|
AU2005295350A1
(en)
*
|
2004-10-20 |
2006-04-27 |
Memory Pharmaceuticals Corporation |
Phosphodiesterase 4 inhibitors
|
|
GT200500281A
(es)
|
2004-10-22 |
2006-04-24 |
Novartis Ag |
Compuestos organicos.
|
|
GB0424284D0
(en)
|
2004-11-02 |
2004-12-01 |
Novartis Ag |
Organic compounds
|
|
GB0426164D0
(en)
|
2004-11-29 |
2004-12-29 |
Novartis Ag |
Organic compounds
|
|
JP2006241111A
(ja)
*
|
2005-03-04 |
2006-09-14 |
Univ Nihon |
新規ベンゾフロキサン及びその合成法
|
|
GB0507577D0
(en)
|
2005-04-14 |
2005-05-18 |
Novartis Ag |
Organic compounds
|
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
|
EP2258359A3
(en)
|
2005-08-26 |
2011-04-06 |
Braincells, Inc. |
Neurogenesis by muscarinic receptor modulation with sabcomelin
|
|
CA2620333A1
(en)
|
2005-08-26 |
2007-03-01 |
Braincells, Inc. |
Neurogenesis by muscarinic receptor modulation
|
|
AU2006304787A1
(en)
|
2005-10-21 |
2007-04-26 |
Braincells, Inc. |
Modulation of neurogenesis by PDE inhibition
|
|
EP2532678A1
(en)
|
2005-10-21 |
2012-12-12 |
Novartis AG |
Human antibodies against il13 and therapeutic uses
|
|
CA2626641A1
(en)
*
|
2005-10-21 |
2007-07-19 |
Glaxo Group Limited |
Compounds
|
|
EP2314289A1
(en)
|
2005-10-31 |
2011-04-27 |
Braincells, Inc. |
Gaba receptor mediated modulation of neurogenesis
|
|
US20070185153A1
(en)
|
2005-12-22 |
2007-08-09 |
Nathalie Cailleau |
Compounds
|
|
GB0526244D0
(en)
|
2005-12-22 |
2006-02-01 |
Novartis Ag |
Organic compounds
|
|
GB0601951D0
(en)
*
|
2006-01-31 |
2006-03-15 |
Novartis Ag |
Organic compounds
|
|
US20100216734A1
(en)
|
2006-03-08 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis by nootropic agents
|
|
RU2457209C2
(ru)
|
2006-04-21 |
2012-07-27 |
Новартис Аг |
Производные пурина, предназначенные для применения в качестве агонистов аденозинового рецептора а2а
|
|
EP2021000A2
(en)
|
2006-05-09 |
2009-02-11 |
Braincells, Inc. |
Neurogenesis by modulating angiotensin
|
|
JP2009536667A
(ja)
|
2006-05-09 |
2009-10-15 |
ブレインセルス,インコーポレイティド |
5ht受容体介在性の神経新生
|
|
MX2009002496A
(es)
|
2006-09-08 |
2009-07-10 |
Braincells Inc |
Combinaciones que contienen un derivado de 4-acilaminopiridina.
|
|
US20100184806A1
(en)
|
2006-09-19 |
2010-07-22 |
Braincells, Inc. |
Modulation of neurogenesis by ppar agents
|
|
JP2010504933A
(ja)
|
2006-09-29 |
2010-02-18 |
ノバルティス アーゲー |
Pi3k脂質キナーゼ阻害剤としてのピラゾロピリミジン
|
|
BRPI0718266A2
(pt)
|
2006-10-30 |
2014-01-07 |
Novartis Ag |
Compostos heterocíclicos como agentes anti-inflamatórios.
|
|
DK2104535T3
(da)
|
2007-01-10 |
2011-04-04 |
Irm Llc |
Forbindelser og sammensætninger som kanalaktiverende proteaseinhibitorer
|
|
BRPI0811562A2
(pt)
|
2007-05-07 |
2014-12-09 |
Novartis Ag |
Compostos orgânicos
|
|
PT2444120T
(pt)
|
2007-12-10 |
2018-01-03 |
Novartis Ag |
Análogos da amilorida espirocíclicos como bloqueadores de enac
|
|
PT2231642E
(pt)
|
2008-01-11 |
2014-03-12 |
Novartis Ag |
Pirimidinas como inibidores de quinase
|
|
US8268834B2
(en)
|
2008-03-19 |
2012-09-18 |
Novartis Ag |
Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
|
|
WO2009150137A2
(en)
|
2008-06-10 |
2009-12-17 |
Novartis Ag |
Organic compounds
|
|
WO2010088335A1
(en)
|
2009-01-29 |
2010-08-05 |
Novartis Ag |
Substituted benzimidazoles for the treatment of astrocytomas
|
|
US20100216805A1
(en)
|
2009-02-25 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis using d-cycloserine combinations
|
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
|
KR20120089643A
(ko)
|
2009-08-12 |
2012-08-13 |
노파르티스 아게 |
헤테로시클릭 히드라존 화합물, 및 암 및 염증을 치료하기 위한 그의 용도
|
|
PE20170003A1
(es)
|
2009-08-17 |
2017-03-15 |
Intellikine Llc |
Compuestos heterociclicos y usos de los mismos
|
|
IN2012DN01453A
(no)
|
2009-08-20 |
2015-06-05 |
Novartis Ag |
|
|
MX2012004792A
(es)
|
2009-10-22 |
2013-02-01 |
Vertex Pharma |
Composiciones para el tratamiento de fibrosis quistica y otras enfermedades cronicas.
|
|
US8247436B2
(en)
|
2010-03-19 |
2012-08-21 |
Novartis Ag |
Pyridine and pyrazine derivative for the treatment of CF
|
|
DK2593452T3
(en)
|
2010-07-14 |
2017-04-24 |
Novartis Ag |
Heterocyclic compounds as IP receptor agonists
|
|
WO2012034095A1
(en)
|
2010-09-09 |
2012-03-15 |
Irm Llc |
Compounds and compositions as trk inhibitors
|
|
US8637516B2
(en)
|
2010-09-09 |
2014-01-28 |
Irm Llc |
Compounds and compositions as TRK inhibitors
|
|
US8372845B2
(en)
|
2010-09-17 |
2013-02-12 |
Novartis Ag |
Pyrazine derivatives as enac blockers
|
|
EP2673277A1
(en)
|
2011-02-10 |
2013-12-18 |
Novartis AG |
[1, 2, 4]triazolo [4, 3 -b]pyridazine compounds as inhibitors of the c-met tyrosine kinase
|
|
WO2012116237A2
(en)
|
2011-02-23 |
2012-08-30 |
Intellikine, Llc |
Heterocyclic compounds and uses thereof
|
|
EA201391230A1
(ru)
|
2011-02-25 |
2014-01-30 |
АйАрЭм ЭлЭлСи |
Соединения и композиции в качестве ингибиторов trk
|
|
US8883819B2
(en)
|
2011-09-01 |
2014-11-11 |
Irm Llc |
Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
|
|
UY34329A
(es)
|
2011-09-15 |
2013-04-30 |
Novartis Ag |
Compuestos de triazolopiridina
|
|
WO2013038378A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine amide derivatives
|
|
WO2013038381A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine/pyrazine amide derivatives
|
|
WO2013038373A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine amide derivatives
|
|
WO2013038386A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Heterocyclic compounds for the treatment of cystic fibrosis
|
|
WO2013038390A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
N-substituted heterocyclyl carboxamides
|
|
WO2013078440A2
(en)
|
2011-11-23 |
2013-05-30 |
Intellikine, Llc |
Enhanced treatment regimens using mtor inhibitors
|
|
WO2013106547A1
(en)
|
2012-01-10 |
2013-07-18 |
President And Fellows Of Harvard College |
Beta-cell replication promoting compounds and methods of their use
|
|
TW201335160A
(zh)
|
2012-01-13 |
2013-09-01 |
Novartis Ag |
Ip受體激動劑之雜環化合物
|
|
US8809340B2
(en)
|
2012-03-19 |
2014-08-19 |
Novartis Ag |
Crystalline form
|
|
WO2013149581A1
(en)
|
2012-04-03 |
2013-10-10 |
Novartis Ag |
Combination products with tyrosine kinase inhibitors and their use
|
|
JP5907006B2
(ja)
*
|
2012-09-04 |
2016-04-20 |
エヌ・イーケムキャット株式会社 |
ビフェニル化合物の合成方法
|
|
JP5907005B2
(ja)
*
|
2012-09-04 |
2016-04-20 |
エヌ・イーケムキャット株式会社 |
ビフェニル化合物の合成方法
|
|
JP2016507582A
(ja)
|
2013-02-13 |
2016-03-10 |
ノバルティス アーゲー |
Ip受容体アゴニスト複素環式化合物
|
|
US9073921B2
(en)
|
2013-03-01 |
2015-07-07 |
Novartis Ag |
Salt forms of bicyclic heterocyclic derivatives
|
|
WO2014151147A1
(en)
|
2013-03-15 |
2014-09-25 |
Intellikine, Llc |
Combination of kinase inhibitors and uses thereof
|
|
TW201605450A
(zh)
|
2013-12-03 |
2016-02-16 |
諾華公司 |
Mdm2抑制劑與BRAF抑制劑之組合及其用途
|
|
JP6433509B2
(ja)
|
2014-04-24 |
2018-12-05 |
ノバルティス アーゲー |
ホスファチジルイノシトール3−キナーゼ阻害薬としてのアミノピラジン誘導体
|
|
BR112016024484A2
(pt)
|
2014-04-24 |
2017-08-15 |
Novartis Ag |
derivados de aminopiridina como inibidores de fosfatidilinositol 3-quinase
|
|
PL3134395T3
(pl)
|
2014-04-24 |
2018-07-31 |
Novartis Ag |
Pochodne pirazyny jako inhibitory 3-kinazy fosfatydyloinozytolu
|
|
US9741941B2
(en)
|
2014-04-29 |
2017-08-22 |
Universal Display Corporation |
Organic electroluminescent materials and devices
|
|
WO2016011658A1
(en)
|
2014-07-25 |
2016-01-28 |
Novartis Ag |
Combination therapy
|
|
EP3174869B1
(en)
|
2014-07-31 |
2020-08-19 |
Novartis AG |
Combination therapy of a met inhibitor and an egfr inhibitor
|
|
MX2021015133A
(es)
|
2019-06-10 |
2022-01-24 |
Novartis Ag |
Derivado de piridina y pirazina para el tratamiento de la fibrosis quistica, enfermedad pulmonar obstructiva cronica y bronquiectasia.
|
|
CR20220060A
(es)
|
2019-08-28 |
2022-03-01 |
Novartis Ag |
Derivados de 1,3-fenil heteroarilo sustituidos y su uso en el tratamiento de enfermedades
|
|
TW202140550A
(zh)
|
2020-01-29 |
2021-11-01 |
瑞士商諾華公司 |
使用抗tslp抗體治療炎性或阻塞性氣道疾病之方法
|