|
US6471956B1
(en)
|
1994-08-17 |
2002-10-29 |
The Rockefeller University |
Ob polypeptides, modified forms and compositions thereto
|
|
US6350730B1
(en)
|
1994-08-17 |
2002-02-26 |
The Rockefeller University |
OB polypeptides and modified forms as modulators of body weight
|
|
US6429290B1
(en)
|
1994-08-17 |
2002-08-06 |
The Rockefeller University |
OB polypeptides, modified forms and derivatives
|
|
US6001968A
(en)
|
1994-08-17 |
1999-12-14 |
The Rockefeller University |
OB polypeptides, modified forms and compositions
|
|
US7597886B2
(en)
|
1994-11-07 |
2009-10-06 |
Human Genome Sciences, Inc. |
Tumor necrosis factor-gamma
|
|
US7429646B1
(en)
|
1995-06-05 |
2008-09-30 |
Human Genome Sciences, Inc. |
Antibodies to human tumor necrosis factor receptor-like 2
|
|
US6936439B2
(en)
|
1995-11-22 |
2005-08-30 |
Amgen Inc. |
OB fusion protein compositions and methods
|
|
US20030040467A1
(en)
|
1998-06-15 |
2003-02-27 |
Mary Ann Pelleymounter |
Ig/ob fusions and uses thereof.
|
|
US7888466B2
(en)
|
1996-01-11 |
2011-02-15 |
Human Genome Sciences, Inc. |
Human G-protein chemokine receptor HSATU68
|
|
US6664227B1
(en)
|
1996-03-01 |
2003-12-16 |
Genetics Institute, Llc |
Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains
|
|
EP0812913A3
(en)
*
|
1996-06-12 |
1999-08-04 |
Smithkline Beecham Corporation |
HR-1 receptor, a receptor of the cytokine receptors family
|
|
US5986059A
(en)
*
|
1996-06-14 |
1999-11-16 |
Bayer Corporation |
T-cell selective interleukin-4 agonists
|
|
US6335426B1
(en)
|
1996-06-14 |
2002-01-01 |
Bayer Corporation |
T-cell selective interleukin-4 agonists
|
|
US6028176A
(en)
|
1996-07-19 |
2000-02-22 |
Bayer Corporation |
High-affinity interleukin-4 muteins
|
|
US6287801B1
(en)
*
|
1996-07-22 |
2001-09-11 |
Smithkline Beecham Corporation |
Nucleic acids encoding the G-protein coupled receptor HNFDS78
|
|
KR100937550B1
(ko)
*
|
1996-12-20 |
2010-01-19 |
암젠 인코포레이티드 |
Ｏｂ 융합 단백질 조성물과 이 단백질의 제조 방법
|
|
US6852508B1
(en)
|
1997-02-28 |
2005-02-08 |
Genetics Institute, Llc |
Chemokine with amino-terminal modifications
|
|
US6100387A
(en)
*
|
1997-02-28 |
2000-08-08 |
Genetics Institute, Inc. |
Chimeric polypeptides containing chemokine domains
|
|
WO1999029732A2
(en)
|
1997-12-08 |
1999-06-17 |
Lexigen Pharmaceuticals Corporation |
Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
|
|
US6057128A
(en)
|
1998-03-17 |
2000-05-02 |
Genetics Institute, Inc. |
MU-1, member of the cytokine receptor family
|
|
US7198789B2
(en)
|
1998-03-17 |
2007-04-03 |
Genetics Institute, Llc |
Methods and compositions for modulating interleukin-21 receptor activity
|
|
WO1999047538A1
(en)
|
1998-03-19 |
1999-09-23 |
Human Genome Sciences, Inc. |
Cytokine receptor common gamma chain like
|
|
AU3501700A
(en)
|
1999-02-26 |
2000-09-14 |
Human Genome Sciences, Inc. |
Human endokine alpha and methods of use
|
|
US20010021380A1
(en)
*
|
1999-04-19 |
2001-09-13 |
Pluenneke John D. |
Soluble tumor necrosis factor receptor treatment of medical disorders
|
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
WO2001010912A1
(en)
|
1999-08-09 |
2001-02-15 |
Lexigen Pharmaceuticals Corp. |
Multiple cytokine-antibody complexes
|
|
JP2003514552A
(ja)
|
1999-11-12 |
2003-04-22 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング |
改善された性質を有するエリトロポエチンの形態
|
|
WO2002043660A2
(en)
|
2000-11-28 |
2002-06-06 |
Mediummune, Inc |
Methods of administering/dosing anti-rsv antibodies for prophylaxis and treatment
|
|
WO2001058957A2
(en)
|
2000-02-11 |
2001-08-16 |
Lexigen Pharmaceuticals Corp. |
Enhancing the circulating half-life of antibody-based fusion proteins
|
|
US20030031675A1
(en)
|
2000-06-06 |
2003-02-13 |
Mikesell Glen E. |
B7-related nucleic acids and polypeptides useful for immunomodulation
|
|
EP1294949A4
(en)
|
2000-06-15 |
2004-08-25 |
Human Genome Sciences Inc |
HUMAN TUMORNESCROSE FACTOR DELTA AND EPSILON
|
|
KR20120053525A
(ko)
|
2000-06-16 |
2012-05-25 |
캠브리지 안티바디 테크놀로지 리미티드 |
면역특이적으로 ＢＬｙＳ에 결합하는 항체
|
|
US7517526B2
(en)
|
2000-06-29 |
2009-04-14 |
Merck Patent Gmbh |
Enhancement of antibody-cytokine fusion protein mediated immune responses by combined treatment with immunocytokine uptake enhancing agents
|
|
ES2727425T3
(es)
|
2000-12-12 |
2019-10-16 |
Medimmune Llc |
Moléculas con semividas prolongadas, composiciones y usos de las mismas
|
|
EP1683865A3
(en)
|
2001-02-02 |
2006-10-25 |
Eli Lilly & Company |
Mammalian proteins and in particular CD200
|
|
ATE470858T1
(de)
*
|
2001-02-22 |
2010-06-15 |
Univ New York State Res Found |
Opiatrezeptoren
|
|
GB0105360D0
(en)
*
|
2001-03-03 |
2001-04-18 |
Glaxo Group Ltd |
Chimaeric immunogens
|
|
EP1366067B1
(en)
|
2001-03-07 |
2012-09-26 |
Merck Patent GmbH |
Expression technology for proteins containing a hybrid isotype antibody moiety
|
|
WO2002079415A2
(en)
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
|
WO2002083704A1
(en)
|
2001-04-13 |
2002-10-24 |
Human Genome Sciences, Inc. |
Vascular endothelial growth factor 2
|
|
DE60239454D1
(de)
|
2001-05-03 |
2011-04-28 |
Merck Patent Gmbh |
Rekombinanter, tumorspezifischer antikörper und dessen verwendung
|
|
DK1572874T3
(da)
|
2001-05-25 |
2013-12-16 |
Human Genome Sciences Inc |
Antistoffer, der immunospecifikt binder til TRAIL receptorer
|
|
US6867189B2
(en)
|
2001-07-26 |
2005-03-15 |
Genset S.A. |
Use of adipsin/complement factor D in the treatment of metabolic related disorders
|
|
ATE542137T1
(de)
|
2001-12-04 |
2012-02-15 |
Merck Patent Gmbh |
Immunocytokine mit modulierter selektivität
|
|
WO2003086458A1
(en)
|
2002-04-12 |
2003-10-23 |
Medimmune, Inc. |
Recombinant anti-interleukin-9 antibodies
|
|
EP1575509B1
(en)
|
2002-05-10 |
2011-10-26 |
Purdue Research Foundation |
Epha2 agonistic monoclonal antibodies and methods of use thereof
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
|
PT1534335E
(pt)
|
2002-08-14 |
2012-02-28 |
Macrogenics Inc |
Anticorpos específicos de fcγriib e processos para a sua utilização
|
|
BRPI0317376B8
(pt)
|
2002-12-17 |
2021-05-25 |
Merck Patent Gmbh |
proteína de fusão de anticorpo-il2 designada como hu14.18-il2, usos da mesma, vetor e composição farmacêutica
|
|
AU2004207476A1
(en)
*
|
2003-01-18 |
2004-08-12 |
Children's Hospital Medical Center |
Regulation of allergen induced gene
|
|
JP2006518997A
(ja)
|
2003-01-21 |
2006-08-24 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規アシルコエンザイムａ：モノアシルグリセロールアシルトランスフェラーゼ−３（ｍｇａｔ３）をコードするポリヌクレオチドおよびその用途
|
|
EP1444989A1
(en)
|
2003-02-07 |
2004-08-11 |
Giorgio Dr. Stassi |
Sensitizing cells for apoptosis by selectively blocking cytokines
|
|
JP5356648B2
(ja)
|
2003-02-20 |
2013-12-04 |
シアトル ジェネティックス， インコーポレイテッド |
抗ｃｄ７０抗体−医薬結合体、ならびに癌および免疫障害の処置のためのそれらの使用
|
|
KR20050119120A
(ko)
|
2003-03-14 |
2005-12-20 |
와이어쓰 |
인간 ⅰｌ-21 수용체에 대한 항체 및 그것의 용도
|
|
EP2316487B1
(en)
|
2003-04-11 |
2014-06-11 |
MedImmune, LLC |
Recombinant IL-9 antibodies & uses thereof
|
|
MXPA05013565A
(es)
*
|
2003-06-12 |
2006-03-09 |
Lilly Co Eli |
Proteinas de fusion analogas al glp-1.
|
|
ES2298785T3
(es)
*
|
2003-06-12 |
2008-05-16 |
Eli Lilly And Company |
Proteinas de fusion.
|
|
CA2536238C
(en)
|
2003-08-18 |
2015-04-07 |
Medimmune, Inc. |
Humanization of antibodies
|
|
WO2005058961A2
(en)
|
2003-12-12 |
2005-06-30 |
Amgen Inc. |
Antibodies specific for human galanin, and uses thereof
|
|
EP1699822B1
(en)
|
2003-12-30 |
2008-04-23 |
MERCK PATENT GmbH |
Il-7 fusion proteins with antibody portions, their preparation and their use
|
|
PT1699821E
(pt)
|
2003-12-31 |
2012-08-23 |
Merck Patent Gmbh |
Proteína de fusão fc-eritropoietina com farmacocinética melhorada
|
|
JP2007517506A
(ja)
|
2004-01-05 |
2007-07-05 |
イーエムディー・レキシゲン・リサーチ・センター・コーポレーション |
標的化用化合物
|
|
WO2005097184A2
(en)
|
2004-03-26 |
2005-10-20 |
Human Genome Sciences, Inc. |
Antibodies against nogo receptor
|
|
SI1751184T1
(sl)
*
|
2004-05-13 |
2010-01-29 |
Lilly Co Eli |
Fgf-21 fuzijski proteini
|
|
AR049390A1
(es)
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
|
US7501121B2
(en)
|
2004-06-17 |
2009-03-10 |
Wyeth |
IL-13 binding agents
|
|
CA2580921C
(en)
|
2004-09-21 |
2016-04-12 |
Medimmune, Inc. |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
|
US7635754B2
(en)
*
|
2004-09-22 |
2009-12-22 |
Aerovance, Inc. |
Interleukin-9 and interleukin-4 chimeric antagonist muteins and methods of using same
|
|
US20060121042A1
(en)
|
2004-10-27 |
2006-06-08 |
Medimmune, Inc. |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
JP2008520684A
(ja)
|
2004-11-17 |
2008-06-19 |
アブジェニックス・インコーポレーテッド |
Ｉｌ−１３に対する完全ヒトモノクローナル抗体
|
|
RU2437893C2
(ru)
|
2004-12-09 |
2011-12-27 |
Мерк Патент Гмбх |
Варианты il-7 со сниженной иммуногенностью
|
|
PL1831252T3
(pl)
*
|
2004-12-22 |
2009-11-30 |
Lilly Co Eli |
Preparaty białka fuzyjnego analogu GLP-1
|
|
JP5153613B2
(ja)
|
2005-03-18 |
2013-02-27 |
メディミューン，エルエルシー |
抗体のフレームワーク・シャッフル
|
|
US8067546B2
(en)
|
2005-04-19 |
2011-11-29 |
Seattle Genetics, Inc. |
Humanized anti-CD70 binding agents and uses thereof
|
|
CN102321174B
(zh)
|
2005-05-06 |
2013-10-16 |
津莫吉尼蒂克斯公司 |
Il-31单克隆抗体及使用方法
|
|
JP2008546805A
(ja)
|
2005-06-23 |
2008-12-25 |
メディミューン，エルエルシー |
最適な凝集および断片化プロフィールを有する抗体製剤
|
|
US7482124B2
(en)
|
2005-07-08 |
2009-01-27 |
Bristol-Myers Squibb Company |
Method of identifying a PPARgamma-agonist compound having a decreased likelihood of inducing dose-dependent peripheral edema
|
|
ZA200804082B
(en)
|
2005-11-07 |
2010-02-24 |
Scripps Research Inst |
Compositions and methods for controlling tissue factor signaling specificity
|
|
US8592149B2
(en)
|
2006-04-27 |
2013-11-26 |
Pikamab, Inc. |
Methods and compositions for antibody therapy
|
|
DK2041576T3
(da)
|
2006-06-21 |
2011-12-05 |
Apogenix Gmbh |
Differentiel cytokinekspression i humane cancere
|
|
PT2029173T
(pt)
|
2006-06-26 |
2016-11-02 |
Macrogenics Inc |
Anticorpos específicos fc rib e seus métodos de uso
|
|
US7572618B2
(en)
|
2006-06-30 |
2009-08-11 |
Bristol-Myers Squibb Company |
Polynucleotides encoding novel PCSK9 variants
|
|
NZ596091A
(en)
|
2006-08-28 |
2012-07-27 |
Jolla Inst Allergy Immunolog |
Antagonistic human light-specific human monoclonal antibodies
|
|
RU2009111884A
(ru)
|
2006-09-01 |
2010-10-10 |
Займоджинетикс, Инк. (Us) |
Последовательности вариабельных областей моноклональных антител против il-31 и способы использования
|
|
US20100143254A1
(en)
|
2006-10-16 |
2010-06-10 |
Medimmune, Llc |
Molecules with reduced half-lives, compositions and uses thereof
|
|
ES2523915T5
(es)
|
2006-12-01 |
2022-05-26 |
Seagen Inc |
Agentes de unión a la diana variantes y usos de los mismos
|
|
WO2008121615A2
(en)
|
2007-03-30 |
2008-10-09 |
Medimmune, Inc. |
Antibody formulation
|
|
US10280211B2
(en)
|
2007-05-04 |
2019-05-07 |
Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa |
Engineered rabbit antibody variable domains and uses thereof
|
|
MX388895B
(es)
|
2007-05-14 |
2025-03-20 |
Astrazeneca Ab |
Metodos para reducir niveles de eosinofilos
|
|
HUE036548T2
(hu)
|
2007-12-07 |
2018-08-28 |
Zymogenetics Inc |
IL-31-re specifikus humanizált antitest molekulák
|
|
JP2011509675A
(ja)
|
2008-01-18 |
2011-03-31 |
メディミューン，エルエルシー |
部位特異的コンジュゲーションのためのシステイン操作抗体
|
|
JP5624535B2
(ja)
|
2008-05-02 |
2014-11-12 |
シアトル ジェネティクス，インコーポレーテッド |
低いコアフコシル化を有する抗体及び抗体誘導体を調製するための方法並びに組成物
|
|
KR101030978B1
(ko)
*
|
2008-07-10 |
2011-04-28 |
(주) 에이프로젠 |
동물세포용 재조합 발현벡터
|
|
AU2009279197B2
(en)
|
2008-08-05 |
2013-12-12 |
Novartis Ag |
Compositions and methods for antibodies targeting complement protein C5
|
|
US8852608B2
(en)
|
2009-02-02 |
2014-10-07 |
Medimmune, Llc |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
|
US20110014190A1
(en)
|
2009-02-12 |
2011-01-20 |
Human Genome Sciences, Inc. |
Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance
|
|
WO2010121766A1
(en)
|
2009-04-22 |
2010-10-28 |
Merck Patent Gmbh |
Antibody fusion proteins with modified fcrn binding sites
|
|
EP2437767B1
(en)
|
2009-06-01 |
2015-07-08 |
MedImmune, LLC |
Molecules with extended half-lives and uses thereof
|
|
US20120213705A1
(en)
|
2009-06-22 |
2012-08-23 |
Medimmune, Llc |
ENGINEERED Fc REGIONS FOR SITE-SPECIFIC CONJUGATION
|
|
MX2012000851A
(es)
|
2009-07-20 |
2012-06-08 |
Squibb Bristol Myers Co |
Combinacion de anticuerpo de anti-antigeno 4 asociado al linfocito t citotoxico con diversos regimenes terapeuticos para tratamiento sinergistico de enfermedades proliferativas.
|
|
EP2464657B1
(en)
|
2009-08-10 |
2015-04-01 |
MorphoSys AG |
Novel screening strategies for the identification of antibodies or fragments thereof which bind an antigen that has an enzymatic activity
|
|
ES2553440T3
(es)
|
2009-08-13 |
2015-12-09 |
Crucell Holland B.V. |
Anticuerpos contra el virus sincitial respiratorio humano (VSR) y método de uso
|
|
AU2010282340B2
(en)
|
2009-08-13 |
2016-12-22 |
The Johns Hopkins University |
Methods of modulating immune function
|
|
US20110189183A1
(en)
|
2009-09-18 |
2011-08-04 |
Robert Anthony Williamson |
Antibodies against candida, collections thereof and methods of use
|
|
EA201291181A1
(ru)
|
2010-05-06 |
2013-05-30 |
Новартис Аг |
Композиции и способы применения терапевтических поливалентных антител против белка, родственного рецептору липопротеинов низкой плотности 6 (lrp6)
|
|
PE20130207A1
(es)
|
2010-05-06 |
2013-02-28 |
Novartis Ag |
Anticuerpos antagonistas de lrp6 (proteina relacionada con lipoproteinas de baja densidad 6) y composiciones
|
|
CN103097412B
(zh)
|
2010-07-09 |
2016-08-10 |
克鲁塞尔荷兰公司 |
抗人呼吸道合胞病毒(rsv)抗体以及使用方法
|
|
EA037095B1
(ru)
|
2010-07-09 |
2021-02-05 |
Биовератив Терапьютикс Инк. |
Способ лечения гемофилии в и эпизодов кровотечения
|
|
WO2012019061A2
(en)
|
2010-08-05 |
2012-02-09 |
Stem Centrx, Inc. |
Novel effectors and methods of use
|
|
BR112013004012B1
(pt)
|
2010-08-20 |
2021-03-23 |
Novartis Ag |
Anticorpo monoclonal isolado ou fragmento de ligação ao antígeno do mesmo ao receptor her3, seu uso e composição farmacêutica
|
|
WO2012027723A1
(en)
|
2010-08-27 |
2012-03-01 |
Stem Centrx, Inc |
Notum protein modulators and methods of use
|
|
BR112013005116A2
(pt)
|
2010-09-03 |
2019-09-24 |
Stem Centrx Inc |
moduladores e métodos de uso
|
|
HUE047228T2
(hu)
|
2010-11-05 |
2020-04-28 |
Zymeworks Inc |
Stabil heterodimer antitest-kialakítás az FC doménben mutációval
|
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
|
NZ728016A
(en)
|
2010-12-08 |
2020-06-26 |
Abbvie Stemcentrx Llc |
Novel modulators and methods of use
|
|
US20120189633A1
(en)
|
2011-01-26 |
2012-07-26 |
Kolltan Pharmaceuticals, Inc. |
Anti-kit antibodies and uses thereof
|
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
|
WO2012170740A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Biomarker of asbestos exposure and mesothelioma
|
|
WO2012170742A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Treatment and prevention of cancer with hmgb1 antagonists
|
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
SG11201400881SA
(en)
|
2011-09-23 |
2014-04-28 |
Technophage Investigação E Desenvolvimento Em Biotecnologia Sa |
Modified albumin-binding domains and uses thereof to improve pharmacokinetics
|
|
US9221907B2
(en)
|
2011-11-01 |
2015-12-29 |
Bionomics Inc. |
Anti-GPR49 monoclonal antibodies
|
|
AU2012332587B2
(en)
|
2011-11-01 |
2017-02-23 |
Bionomics, Inc. |
Antibodies and methods of treating cancer
|
|
EP2773664A1
(en)
|
2011-11-01 |
2014-09-10 |
Bionomics, Inc. |
Anti-gpr49 antibodies
|
|
ES2697674T3
(es)
|
2011-11-01 |
2019-01-25 |
Bionomics Inc |
Procedimientos para bloquear el crecimiento de células madre cancerosas
|
|
JP6326371B2
(ja)
|
2011-11-04 |
2018-05-16 |
ザイムワークス，インコーポレイテッド |
Ｆｃドメインにおける変異を有する安定なヘテロ二量体抗体デザイン
|
|
AR088633A1
(es)
|
2011-11-04 |
2014-06-25 |
Novartis Ag |
Constructos extensores de vida media de lrp6 (proteina relacionada con lipoproteinas de baja densidad 6)
|
|
WO2013081993A1
(en)
|
2011-12-02 |
2013-06-06 |
Eli Lilly And Company |
Anti-glucagon antibodies and uses thereof
|
|
WO2013084147A2
(en)
|
2011-12-05 |
2013-06-13 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (her3)
|
|
CN104105709A
(zh)
|
2011-12-05 |
2014-10-15 |
诺华股份有限公司 |
抗her3的结构域ii的表皮生长因子受体3(her3)抗体
|
|
SG10201703249PA
(en)
|
2011-12-21 |
2017-05-30 |
Novartis Ag |
Compositions and methods for antibodies targeting factor p
|
|
EP2794653B1
(en)
|
2011-12-23 |
2019-03-13 |
Pfizer Inc |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
|
PE20190658A1
(es)
|
2012-02-24 |
2019-05-08 |
Abbvie Stemcentrx Llc |
Moduladores y metodos de empleo novedosos
|
|
WO2013126810A1
(en)
|
2012-02-24 |
2013-08-29 |
Stem Centrx, Inc. |
Anti sez6 antibodies and methods of use
|
|
JP6351572B2
(ja)
|
2012-05-10 |
2018-07-04 |
ザイムワークス，インコーポレイテッド |
Ｆｃドメインに突然変異を有する免疫グロブリン重鎖のヘテロ多量体構築物
|
|
NZ630363A
(en)
|
2012-07-25 |
2018-09-28 |
Celldex Therapeutics Inc |
Anti-kit antibodies and uses thereof
|
|
SG11201502757QA
(en)
|
2012-10-09 |
2015-05-28 |
Igenica Biotherapeutics Inc |
Anti-c16orf54 antibodies and methods of use thereof
|
|
WO2014084859A1
(en)
|
2012-11-30 |
2014-06-05 |
Novartis Ag |
Molecules and methods for modulating tmem16a activities
|
|
EP2928921B1
(en)
|
2012-12-05 |
2021-01-20 |
Novartis AG |
Compositions and methods for antibodies targeting epo
|
|
EA201591176A1
(ru)
|
2012-12-18 |
2016-02-29 |
Новартис Аг |
Композиции и способы с использованием пептидной метки, связывающейся с гиалуронаном
|
|
RU2019109456A
(ru)
|
2013-02-22 |
2019-04-10 |
ЭББВИ СТЕМСЕНТРКС ЭлЭлСи |
Новые конъюгаты антител и их применения
|
|
EP3611189A1
(en)
|
2013-03-14 |
2020-02-19 |
Novartis AG |
Antibodies against notch 3
|
|
DK2970473T3
(da)
|
2013-03-14 |
2017-11-27 |
Bristol Myers Squibb Co |
Kombination af dr5-agonist og anti-pd-1-antagonist og fremgangsmåder til anvendelse heraf
|
|
CN103265637B
(zh)
*
|
2013-06-04 |
2015-10-21 |
江苏众红生物工程创药研究院有限公司 |
一种重组猪白细胞介素4-Fc融合蛋白及其编码基因和表达方法
|
|
EP3003390B1
(en)
|
2013-06-06 |
2021-07-07 |
Pierre Fabre Médicament |
Anti-c10orf54 antibodies and uses thereof
|
|
AR096601A1
(es)
|
2013-06-21 |
2016-01-20 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
|
UY35620A
(es)
|
2013-06-21 |
2015-01-30 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
|
KR20160054501A
(ko)
|
2013-08-26 |
2016-05-16 |
맵백스 테라퓨틱스, 인코포레이티드 |
시알릴-루이스 ａ에 대한 사람 항체 코드화 핵산
|
|
RU2016111131A
(ru)
|
2013-08-28 |
2017-10-03 |
ЭББВИ СТЕМСЕНТРКС ЭлЭлСи |
Способы конъюгации сайт-специфических антител и композиции
|
|
WO2015031541A1
(en)
|
2013-08-28 |
2015-03-05 |
Stem Centrx, Inc. |
Novel sez6 modulators and methods of use
|
|
WO2015065954A1
(en)
|
2013-11-04 |
2015-05-07 |
Pfizer, Inc. |
Anti-efna4 antibody-drug conjugates
|
|
PE20170256A1
(es)
|
2014-01-24 |
2017-04-22 |
Ngm Biopharmaceuticals Inc |
Proteinas de union y sus metodos de uso
|
|
AU2015218633A1
(en)
|
2014-02-21 |
2016-09-01 |
Abbvie Stemcentrx Llc |
Anti-DLL3 antibodies and drug conjugates for use in melanoma
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
CA2944649C
(en)
|
2014-04-04 |
2022-06-21 |
Bionomics, Inc. |
Humanized antibodies that bind lgr5
|
|
US10329556B2
(en)
|
2014-05-13 |
2019-06-25 |
Bioatla, Llc |
Conditionally active biological proteins
|
|
EP3142700B1
(en)
|
2014-05-16 |
2021-03-03 |
Medimmune, LLC |
Molecules with altered neonate fc receptor binding having enhanced therapeutic and diagnostic properties
|
|
HUE055189T2
(hu)
|
2014-06-04 |
2021-11-29 |
Biontech Res And Development Inc |
Humán monoklonális antitestek a GD2 ganglioziddal ellen
|
|
EP3160991A2
(en)
|
2014-06-25 |
2017-05-03 |
Novartis AG |
Compositions and methods for long acting proteins
|
|
US20170290876A1
(en)
|
2014-06-25 |
2017-10-12 |
Novartis Ag |
Compositions and methods for long acting proteins
|
|
EP3161001A2
(en)
|
2014-06-25 |
2017-05-03 |
Novartis AG |
Antibodies specific for il-17a fused to hyaluronan binding peptide tags
|
|
SG11201700473QA
(en)
|
2014-08-07 |
2017-02-27 |
Novartis Ag |
Angiopoietin-like 4 antibodies and methods of use
|
|
WO2016020882A2
(en)
|
2014-08-07 |
2016-02-11 |
Novartis Ag |
Angiopoetin-like 4 (angptl4) antibodies and methods of use
|
|
KR20170044115A
(ko)
|
2014-09-03 |
2017-04-24 |
바이오아트라, 엘엘씨 |
동일한 진핵생물 세포 생산 숙주 내 조건부 활성 생체 단백질의 발견 및 제조
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
DK3333191T3
(da)
|
2014-12-11 |
2020-10-26 |
Pf Medicament |
Anti-C10ORF54-antistoffer og anvendelser deraf
|
|
UY36449A
(es)
|
2014-12-19 |
2016-07-29 |
Novartis Ag |
Composiciones y métodos para anticuerpos dirigidos a bmp6
|
|
JP7025214B2
(ja)
|
2015-02-24 |
2022-02-24 |
バイオアトラ、エルエルシー |
条件的活性型生物学的タンパク質
|
|
RU2725221C2
(ru)
|
2015-03-03 |
2020-06-30 |
Кимаб Лимитед |
Антитела, их применение и способы применения
|
|
CN107614526A
(zh)
|
2015-06-05 |
2018-01-19 |
诺华股份有限公司 |
靶向骨形成蛋白9(bmp9)的抗体及其方法
|
|
JOP20200312A1
(ar)
|
2015-06-26 |
2017-06-16 |
Novartis Ag |
الأجسام المضادة للعامل xi وطرق الاستخدام
|
|
CN115043944B
(zh)
|
2015-08-03 |
2024-08-20 |
诺华股份有限公司 |
治疗fgf21相关病症的方法
|
|
CU24533B1
(es)
|
2015-09-09 |
2021-07-02 |
Novartis Ag |
Anticuerpos o fragmentos de los mismos que se unen a linfopoyetina estromal tímica (tslp) y composiciones farmacéuticas de los mismos
|
|
TN2018000076A1
(en)
|
2015-09-09 |
2019-07-08 |
Novartis Ag |
Thymic stromal lymphopoietin (tslp)-binding molecules and methods of using the molecules
|
|
HK1251158A1
(zh)
|
2015-09-29 |
2019-01-25 |
细胞基因公司 |
Pd-1结合蛋白及其使用方法
|
|
CN108473555B
(zh)
|
2015-11-02 |
2022-10-25 |
生物蛋白有限公司 |
条件活性多肽
|
|
BR112018010937A2
(pt)
|
2015-12-04 |
2018-12-04 |
Novartis Ag |
composições de anticorpos enxertados com citocina e métodos de uso para imunorregulação
|
|
CN109069623A
(zh)
|
2015-12-18 |
2018-12-21 |
诺华股份有限公司 |
靶向CD32b的抗体及其使用方法
|
|
WO2017125897A1
(en)
|
2016-01-21 |
2017-07-27 |
Novartis Ag |
Multispecific molecules targeting cll-1
|
|
KR20180138205A
(ko)
|
2016-03-22 |
2018-12-28 |
바이오노믹스 리미티드 |
항-lgr5 단클론성 항체의 투여
|
|
WO2017189724A1
(en)
|
2016-04-27 |
2017-11-02 |
Novartis Ag |
Antibodies against growth differentiation factor 15 and uses thereof
|
|
TW201802121A
(zh)
|
2016-05-25 |
2018-01-16 |
諾華公司 |
抗因子XI/XIa抗體之逆轉結合劑及其用途
|
|
CN110381988A
(zh)
|
2016-06-15 |
2019-10-25 |
诺华股份有限公司 |
使用骨形态发生蛋白6(bmp6)的抑制剂治疗疾病的方法
|
|
WO2018009507A1
(en)
|
2016-07-06 |
2018-01-11 |
Bristol-Myers Squibb Company |
Combination of tim-4 antagonist and methods of use
|
|
KR102257154B1
(ko)
|
2016-09-19 |
2021-05-28 |
셀진 코포레이션 |
Pd-1 결합 단백질을 사용하는 면역 질환의 치료 방법
|
|
US10766958B2
(en)
|
2016-09-19 |
2020-09-08 |
Celgene Corporation |
Methods of treating vitiligo using PD-1 binding antibodies
|
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
KR102616666B1
(ko)
|
2016-12-23 |
2023-12-27 |
노파르티스 아게 |
인자 xi 항체 및 사용 방법
|
|
CA3048157A1
(en)
|
2016-12-23 |
2018-06-28 |
Novartis Ag |
Methods of treatment with anti-factor xi/xia antibodies
|
|
EP3580237B1
(en)
|
2017-02-08 |
2025-05-14 |
Novartis AG |
Fgf21 mimetic antibodies and uses thereof
|
|
CN111107868A
(zh)
|
2017-05-24 |
2020-05-05 |
诺华股份有限公司 |
抗体细胞因子移植蛋白及使用方法
|
|
EA201992765A1
(ru)
|
2017-05-24 |
2020-03-25 |
Новартис Аг |
Белки на основе антител с привитым цитокином и способы их применения в лечении рака
|
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
|
JOP20190271A1
(ar)
|
2017-05-24 |
2019-11-21 |
Novartis Ag |
بروتينات مطعّمة بسيتوكين- الجسم المضاد وطرق الاستخدام للاضطرابات المتعلقة بالمناعة
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
JP7256796B2
(ja)
|
2017-10-13 |
2023-04-12 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｔｈｏｍｓｅｎ－ｎｏｕｖｅｌｌｅ（ｔｎ）抗原に対するヒト抗体
|
|
EP3700933A1
(en)
|
2017-10-25 |
2020-09-02 |
Novartis AG |
Antibodies targeting cd32b and methods of use thereof
|
|
CN112004558A
(zh)
|
2018-04-12 |
2020-11-27 |
米迪亚制药有限责任公司 |
Lgals3bp抗体-药物-偶联物及其用于癌症的治疗的用途
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
IL317554A
(en)
|
2018-06-01 |
2025-02-01 |
Novartis Ag |
Anti-BCMA binding molecules and their uses
|
|
US20230243836A1
(en)
|
2018-07-20 |
2023-08-03 |
Pierre Fabre Medicament |
Receptor for vista
|
|
CN113166245B
(zh)
|
2018-09-27 |
2024-12-20 |
细胞基因公司 |
SIRPα结合蛋白及其使用方法
|
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
|
US20220169706A1
(en)
|
2019-03-28 |
2022-06-02 |
Danisco Us Inc |
Engineered antibodies
|
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
|
CN113874398B
(zh)
|
2019-05-21 |
2025-08-01 |
诺华股份有限公司 |
Cd19结合分子及其用途
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與ｅｎｔｐｄ２抗體之組合療法
|
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
TWI877278B
(zh)
|
2019-12-30 |
2025-03-21 |
美商思進公司 |
以非海藻糖苷化抗－ｃｄ７０抗體治療癌症之方法
|
|
US20230203191A1
(en)
|
2020-03-30 |
2023-06-29 |
Danisco Us Inc |
Engineered antibodies
|
|
CN116096758A
(zh)
|
2020-05-01 |
2023-05-09 |
诺华股份有限公司 |
工程化免疫球蛋白
|
|
US20230167193A1
(en)
|
2020-05-01 |
2023-06-01 |
Novartis Ag |
Immunoglobulin variants
|
|
CN116322776A
(zh)
|
2020-08-03 |
2023-06-23 |
詹森生物科技公司 |
用于病毒治疗剂中的多向生物转运的材料和方法
|
|
AU2021373366A1
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
US20250199010A1
(en)
|
2020-12-31 |
2025-06-19 |
Alamar Biosciences, Inc. |
Binder molecules with high affinity and/ or specificity and methods of making and use thereof
|
|
TW202317190A
(zh)
|
2021-06-29 |
2023-05-01 |
美商思進公司 |
以非岩藻糖基化抗ｃｄ７０抗體及ｃｄ４７拮抗劑之組合治療癌症之方法
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
CN119072493A
(zh)
|
2022-04-26 |
2024-12-03 |
诺华股份有限公司 |
靶向il-13和il-18的多特异性抗体
|
|
EP4554619A1
(en)
|
2022-07-15 |
2025-05-21 |
Danisco US Inc. |
Methods for producing monoclonal antibodies
|
|
CN119948051A
(zh)
|
2022-07-15 |
2025-05-06 |
詹森生物科技公司 |
用于改善抗原结合可变区的生物工程化配对的材料和方法
|
|
EP4612165A1
(en)
*
|
2022-11-02 |
2025-09-10 |
Synerkine Pharma B.V. |
Engineered immunocytokines, fusion polypeptides, and il10 polypeptides
|
|
WO2024130158A1
(en)
|
2022-12-16 |
2024-06-20 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease
|
|
WO2025104604A1
(en)
|
2023-11-14 |
2025-05-22 |
Janssen Pharmaceuticals, Inc. |
Anti-respiratory syncytial virus antibodies and uses thereof
|