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BG62794B1 - Метод за получаване на лекарствена форма на карбамазепин съсзабавено освобождаване на активното вещество - Google Patents

Метод за получаване на лекарствена форма на карбамазепин съсзабавено освобождаване на активното вещество Download PDF

Info

Publication number
BG62794B1
BG62794B1 BG101080A BG10108096A BG62794B1 BG 62794 B1 BG62794 B1 BG 62794B1 BG 101080 A BG101080 A BG 101080A BG 10108096 A BG10108096 A BG 10108096A BG 62794 B1 BG62794 B1 BG 62794B1
Authority
BG
Bulgaria
Prior art keywords
carbamazepine
film
ratio
plasticizer
carbamasepin
Prior art date
Application number
BG101080A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101080A (en
Inventor
Karl-Friedrich Landgraf
Sabine Reiss
Eberhard Schubert
Original Assignee
Arzneimittelwerk Dresden Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arzneimittelwerk Dresden Gmbh filed Critical Arzneimittelwerk Dresden Gmbh
Publication of BG101080A publication Critical patent/BG101080A/xx
Publication of BG62794B1 publication Critical patent/BG62794B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG101080A 1994-07-01 1996-12-28 Метод за получаване на лекарствена форма на карбамазепин съсзабавено освобождаване на активното вещество BG62794B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19944423078 DE4423078B4 (de) 1994-07-01 1994-07-01 Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung
PCT/DE1995/000805 WO1996001112A1 (de) 1994-07-01 1995-06-22 Carbamazepin-arzneiform mit verzögerter wirkstofffreisetzung

Publications (2)

Publication Number Publication Date
BG101080A BG101080A (en) 1997-08-29
BG62794B1 true BG62794B1 (bg) 2000-08-31

Family

ID=6522000

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101080A BG62794B1 (bg) 1994-07-01 1996-12-28 Метод за получаване на лекарствена форма на карбамазепин съсзабавено освобождаване на активното вещество

Country Status (23)

Country Link
US (1) US5888545A (lt)
EP (1) EP0768882B1 (lt)
JP (1) JPH10502358A (lt)
KR (1) KR100344477B1 (lt)
CN (1) CN1101191C (lt)
AT (1) ATE169818T1 (lt)
BG (1) BG62794B1 (lt)
BR (1) BR9508202A (lt)
CA (1) CA2194216A1 (lt)
CZ (1) CZ288028B6 (lt)
DE (2) DE4423078B4 (lt)
DK (1) DK0768882T3 (lt)
EE (1) EE03954B1 (lt)
ES (1) ES2122630T3 (lt)
GE (1) GEP19991819B (lt)
HU (1) HU221486B (lt)
LT (1) LT4251B (lt)
LV (1) LV11820B (lt)
PL (1) PL180979B1 (lt)
RU (1) RU2141825C1 (lt)
SK (1) SK282303B6 (lt)
UA (1) UA32598C2 (lt)
WO (1) WO1996001112A1 (lt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162466A (en) * 1999-04-15 2000-12-19 Taro Pharmaceutical Industries Ltd. Sustained release formulation of carbamazepine
GB9930058D0 (en) * 1999-12-20 2000-02-09 Novartis Ag Organic compounds
RU2240798C1 (ru) * 2003-06-25 2004-11-27 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция, обладающая противосудорожным и психотропным действием, и способ ее получения
AU2006239838A1 (en) * 2005-04-25 2006-11-02 Teva Pharmaceuticals Usa, Inc. Extended release formulations
DK1940467T3 (da) * 2005-09-09 2017-02-13 Paladin Labs Inc Lægemiddelsammensætning med langvarig frigivelse
SI1931346T1 (sl) * 2005-09-09 2012-10-30 Angelini Labopharm Llc Trazodonski sestavek za dajanje enkrat dnevno
US20070160960A1 (en) * 2005-10-21 2007-07-12 Laser Shot, Inc. System and method for calculating a projectile impact coordinates
RU2361591C1 (ru) * 2007-10-03 2009-07-20 Общество с ограниченной ответственностью "Научно-производственное объединение "Фарматрон" (НПО "Фарматрон") Противосудорожное лекарственное средство
FR2940910A1 (fr) * 2009-01-09 2010-07-16 Vetoquinol Sa Nouveau comprime a base de s-adenosyl-methionine
CN105997916A (zh) * 2016-07-19 2016-10-12 南京正宽医药科技有限公司 一种卡马西平片及其制备方法
CN108125922A (zh) * 2018-01-14 2018-06-08 上海安必生制药技术有限公司 一种卡马西平口服缓释制剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
SE8203953D0 (sv) * 1982-06-24 1982-06-24 Astra Laekemedel Ab Pharmaceutical mixture
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
CH668187A5 (de) * 1986-08-07 1988-12-15 Ciba Geigy Ag Therapeutisches system mit systemischer wirkung.
IL86211A (en) * 1987-05-04 1992-03-29 Ciba Geigy Ag Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
US5326572A (en) * 1989-03-23 1994-07-05 Fmc Corporation Freeze-dried polymer dispersions and the use thereof in preparing sustained-release pharmaceutical compositions

Also Published As

Publication number Publication date
BG101080A (en) 1997-08-29
CN1101191C (zh) 2003-02-12
HU221486B (en) 2002-10-28
UA32598C2 (uk) 2001-02-15
BR9508202A (pt) 1997-11-11
HU9603565D0 (en) 1997-02-28
CZ288028B6 (cs) 2001-04-11
HUT76821A (en) 1997-11-28
GEP19991819B (en) 1999-11-05
KR970703774A (ko) 1997-08-09
LT4251B (en) 1997-12-29
LV11820B (en) 1997-12-20
PL317996A1 (en) 1997-05-12
WO1996001112A1 (de) 1996-01-18
CZ382696A3 (en) 1997-05-14
DE59503283D1 (de) 1998-09-24
DE4423078B4 (de) 2005-01-13
LT97012A (en) 1997-08-25
EP0768882A1 (de) 1997-04-23
SK282303B6 (sk) 2002-01-07
RU2141825C1 (ru) 1999-11-27
SK164696A3 (en) 1997-06-04
LV11820A (lv) 1997-08-20
KR100344477B1 (ko) 2002-11-23
EE9600202A (et) 1997-06-16
DE4423078A1 (de) 1996-01-04
JPH10502358A (ja) 1998-03-03
DK0768882T3 (da) 1999-05-25
PL180979B1 (pl) 2001-05-31
EE03954B1 (et) 2003-02-17
EP0768882B1 (de) 1998-08-19
ATE169818T1 (de) 1998-09-15
CA2194216A1 (en) 1996-01-18
CN1153475A (zh) 1997-07-02
ES2122630T3 (es) 1998-12-16
US5888545A (en) 1999-03-30

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