[go: up one dir, main page]

BE2011C027I2 - - Google Patents

Download PDF

Info

Publication number
BE2011C027I2
BE2011C027I2 BE2011C027C BE2011C027C BE2011C027I2 BE 2011C027 I2 BE2011C027 I2 BE 2011C027I2 BE 2011C027 C BE2011C027 C BE 2011C027C BE 2011C027 C BE2011C027 C BE 2011C027C BE 2011C027 I2 BE2011C027 I2 BE 2011C027I2
Authority
BE
Belgium
Prior art keywords
aqueous liquid
liquid preparation
rhinitis
preservative
useful
Prior art date
Application number
BE2011C027C
Other languages
English (en)
French (fr)
Original Assignee
Senju Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32767329&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE2011C027(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senju Pharma Co filed Critical Senju Pharma Co
Publication of BE2011C027I2 publication Critical patent/BE2011C027I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE2011C027C 2003-01-21 2011-08-30 BE2011C027I2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003012427 2003-01-21

Publications (1)

Publication Number Publication Date
BE2011C027I2 true BE2011C027I2 (es) 2023-03-07

Family

ID=32767329

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2011C027C BE2011C027I2 (es) 2003-01-21 2011-08-30

Country Status (15)

Country Link
US (9) US8129431B2 (es)
EP (1) EP1586316B1 (es)
JP (1) JP4500261B2 (es)
KR (1) KR101059711B1 (es)
CN (1) CN100341498C (es)
AT (1) ATE393627T1 (es)
BE (1) BE2011C027I2 (es)
CA (2) CA2944832C (es)
DE (2) DE122011100019I1 (es)
ES (1) ES2301964T3 (es)
FR (1) FR11C0031I2 (es)
HU (1) HUS1100022I1 (es)
MX (1) MX2016014404A (es)
PT (1) PT1586316E (es)
WO (2) WO2004064828A1 (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6552020B1 (en) * 1999-07-30 2003-04-22 Allergan, Inc. Compositions including antibiotics and methods for using same
KR101059711B1 (ko) * 2003-01-21 2011-08-29 센주 세이야꾸 가부시키가이샤 2-아미노-3-(4-브로모벤조일)페닐아세트산 함유 수성액제
JP4933897B2 (ja) * 2004-11-05 2012-05-16 千寿製薬株式会社 眼内移行性促進水性点眼剤
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
EP1981491A4 (en) * 2006-01-25 2009-09-23 Aciex Inc COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC DROUGHT
AU2008219600A1 (en) * 2007-02-28 2008-09-04 Aciex Therapeutics, Inc. Methods and compositions for normalizing meibomian gland secretions
EP2160182A1 (en) * 2007-05-24 2010-03-10 Aciex Therapeutics, Inc. Formulations and methods for treating dry eye
CN101313899B (zh) * 2007-06-01 2012-02-29 北京德众万全药物技术开发有限公司 一种含有溴芬酸钠的眼用药物组合物
WO2009105534A2 (en) * 2008-02-21 2009-08-27 Ista Pharmaceuticals Ophthalmic nsaids as adjuvants
DK2420223T3 (da) * 2008-03-17 2017-11-06 Novartis Ag Vandige farmaceutiske sammensætninger med borat-polyol-komplekser
US8778999B2 (en) * 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
TWI489997B (zh) * 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
GB2484843A (en) * 2009-10-15 2012-04-25 Johnson Matthey Plc Polymorphs of Bromfenac sodium
US8299295B2 (en) 2009-10-15 2012-10-30 Johnson Matthey Public Limited Company Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
GB0919757D0 (en) * 2009-11-12 2009-12-30 Johnson Matthey Plc Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
EP2498768A1 (en) * 2009-11-11 2012-09-19 Micro Labs Limited Pharmaceutical combination of prostaglandin compound and nsaid for the treatment of glaucoma and ocular hypertension
CN103379904A (zh) * 2011-01-18 2013-10-30 千寿制药株式会社 具有保存效能的溴芬酸水性液剂组合物
JP6012231B2 (ja) * 2011-04-08 2016-10-25 ロート製薬株式会社 ブロムフェナク含有組成物
EP2701682A1 (en) 2011-04-29 2014-03-05 Allergan, Inc. Solvent cast film sustained release latanoprost implant
US20130023575A1 (en) * 2011-07-22 2013-01-24 Kamran Hosseini Compositions and methods for the treatment of ocular surface allergies
ES2992712T3 (en) 2011-10-12 2024-12-17 Bausch & Lomb Ocular composition containing bromfenac with increased bioavailability
US20130217657A1 (en) * 2011-12-21 2013-08-22 Insite Vision Incorporated Combination anti-inflammatory ophthalmic compositions
US20130165419A1 (en) * 2011-12-21 2013-06-27 Insite Vision Incorporated Combination anti-inflammatory ophthalmic compositions
CN104661682B (zh) * 2012-09-27 2018-05-11 千寿制药株式会社 水性液剂
JP6161500B2 (ja) * 2012-10-05 2017-07-12 ロート製薬株式会社 ブロムフェナク含有組成物
WO2014078766A1 (en) 2012-11-19 2014-05-22 Bausch & Lomb Incorporated Aqueous liquid composition containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
WO2014120293A1 (en) * 2013-01-31 2014-08-07 Sentiss Pharma Pvt.Ltd. Ophthalmic formulations
BR112015017919A8 (pt) 2013-01-31 2019-11-05 Senju Pharma Co preparação líquida aquosa e método para clarificar uma preparação líquida aquosa
KR20150110775A (ko) * 2013-01-31 2015-10-02 센주 세이야꾸 가부시키가이샤 안정한 수성액제
US20160143869A1 (en) 2013-06-19 2016-05-26 Sentiss Research Center Stable bromfenac solution
JP2015086222A (ja) * 2013-09-26 2015-05-07 参天製薬株式会社 安定化された２−アミノ−３−（４−ブロモベンゾイル）フェニル酢酸含有水性組成物
WO2015087267A2 (en) * 2013-12-12 2015-06-18 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
CN104151182B (zh) * 2014-06-16 2016-03-30 广东众生药业股份有限公司 一种溴芬酸钠倍半水合物的制备方法
US11452732B2 (en) 2015-09-05 2022-09-27 Randal Davis Homogeneous ophthalmic composition
US10130639B1 (en) 2015-09-05 2018-11-20 Randal Davis Homogeneous ophthalmic composition
CN106404952B (zh) * 2016-08-31 2019-06-11 辰欣佛都药业（汶上）有限公司 一种溴芬酸钠滴眼液有关物质的测定方法

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2880130A (en) 1956-12-24 1959-03-31 Upjohn Co Anti-inflammatory steroid solutions
US2880138A (en) 1956-12-24 1959-03-31 Upjohn Co Anti-inflammatory steroid solutions
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
US4683242A (en) 1985-10-28 1987-07-28 A. H. Robins Company, Incorporated Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters
GB8630273D0 (en) 1986-12-18 1987-01-28 Til Medical Ltd Pharmaceutical delivery systems
CA1328614C (en) * 1987-09-11 1994-04-19 Cherng-Chyi Roger Fu Preservative system for ophthalmics formulations
US5414011A (en) 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
US5110493A (en) * 1987-09-11 1992-05-05 Syntex (U.S.A.) Inc. Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
CA1325382C (en) * 1988-01-27 1993-12-21 Takahiro Ogawa Locally administrable therapeutic composition for inflammatory disease
JPH0283323A (ja) * 1988-09-20 1990-03-23 Zeria Pharmaceut Co Ltd 安定な酪酸リボフラビン水溶液
JPH02124819A (ja) 1988-11-01 1990-05-14 Mitsubishi Kasei Corp 経口コレステロール低下剤
JPH05223052A (ja) 1992-02-06 1993-08-31 Kanematsu Eng Kk 波浪エネルギ−を利用した電流発生装置及びこの電流発生装置が備えられた水素ガス発生装置
WO1994005298A1 (en) 1992-08-28 1994-03-17 Pharmos Corporation Submicron emulsions as ocular drug delivery vehicles
AU6021794A (en) 1993-01-11 1994-08-15 Allergan, Inc. Ophthalmic compositions comprising benzyllauryldimethylammonium chloride
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
LT3969B (en) 1994-03-15 1996-05-27 Senju Pharma Co Method for stabilizing pranoprofen and stable liquid preparation of pranoprofen
ES2079320B1 (es) * 1994-05-17 1996-10-16 Cusi Lab Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones.
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
CA2201134A1 (en) 1994-10-10 1996-04-18 Alfred Sallmann Ophthalmic and aural compositions containing diclofenac potassium
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
US5750564A (en) * 1995-09-12 1998-05-12 Hellberg; Mark Anti-oxidant esters of non-steroidal anti-inflammatory agents
US6071904A (en) * 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
US5942508A (en) * 1997-02-04 1999-08-24 Senju Pharmaceutical Co., Ltd. Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid
US6274592B1 (en) * 1997-02-04 2001-08-14 Senju Pharmaceutical Co., Ltd. Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
TW546151B (en) 1997-07-23 2003-08-11 Senju Pharma Co Aqueous liquid pharmaceutical composition containing as main component benzopyran derivative
JPH11228404A (ja) * 1997-12-11 1999-08-24 Senju Pharmaceut Co Ltd 安定な水性点眼剤
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6162393A (en) * 1998-08-06 2000-12-19 Ndt, Inc. Contact lens and ophthalmic solutions
US6319513B1 (en) * 1998-08-24 2001-11-20 The Procter & Gamble Company Oral liquid mucoadhesive compounds
US6395746B1 (en) * 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6369112B1 (en) * 1998-12-15 2002-04-09 Bausch & Lomb Incorporated Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by tyloxapol
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
WO2001015677A2 (en) 1999-08-31 2001-03-08 Alcon Laboratories, Inc. Use of 5-ht1b/1d agonists to treat otic pain
NZ517556A (en) 1999-09-06 2003-08-29 Ono Pharmaceutical Co N-[o-(p-pivaloyloxybenzenesulphonyl-amino)benzoyl]glycine as preventive and therapeutic agents for eye diseases
AR030345A1 (es) 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
JP2002308764A (ja) * 2001-02-09 2002-10-23 Taisho Pharmaceut Co Ltd 眼科用医薬組成物
KR101059711B1 (ko) * 2003-01-21 2011-08-29 센주 세이야꾸 가부시키가이샤 2-아미노-3-(4-브로모벤조일)페닐아세트산 함유 수성액제
ATE552838T1 (de) * 2003-11-14 2012-04-15 Senju Pharma Co Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac
JP5223052B2 (ja) 2010-05-21 2013-06-26 春誠 鈴木 コーキングガン
ES2992712T3 (en) * 2011-10-12 2024-12-17 Bausch & Lomb Ocular composition containing bromfenac with increased bioavailability
WO2014078766A1 (en) * 2012-11-19 2014-05-22 Bausch & Lomb Incorporated Aqueous liquid composition containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid

Also Published As

Publication number Publication date
FR11C0031I2 (fr) 2012-03-16
US20140243413A1 (en) 2014-08-28
DE122011100019I1 (de) 2011-11-03
CN1700913A (zh) 2005-11-23
KR101059711B1 (ko) 2011-08-29
US9144609B2 (en) 2015-09-29
WO2004064828A1 (ja) 2004-08-05
EP1586316B1 (en) 2008-04-30
US8927606B1 (en) 2015-01-06
US8497304B2 (en) 2013-07-30
US20150025149A1 (en) 2015-01-22
ATE393627T1 (de) 2008-05-15
CA3043910A1 (en) 2015-11-12
KR20050092691A (ko) 2005-09-22
DE602004013420T2 (de) 2009-06-04
CA2944832C (en) 2019-10-08
US20050239895A1 (en) 2005-10-27
US20140235721A1 (en) 2014-08-21
US20070287749A1 (en) 2007-12-13
US20140142183A1 (en) 2014-05-22
CN100341498C (zh) 2007-10-10
US20130090384A1 (en) 2013-04-11
JPWO2004064828A1 (ja) 2006-05-18
WO2015170177A1 (en) 2015-11-12
US8129431B2 (en) 2012-03-06
DE602004013420D1 (de) 2008-06-12
HK1083468A1 (en) 2006-07-07
US8754131B2 (en) 2014-06-17
EP1586316A1 (en) 2005-10-19
ES2301964T3 (es) 2008-07-01
MX2016014404A (es) 2017-10-27
US20150011634A1 (en) 2015-01-08
JP4500261B2 (ja) 2010-07-14
US20120115957A1 (en) 2012-05-10
PT1586316E (pt) 2008-05-28
US8871813B2 (en) 2014-10-28
US8669290B2 (en) 2014-03-11
CA2944832A1 (en) 2015-11-12
EP1586316A4 (en) 2007-06-27
US9561277B2 (en) 2017-02-07
HUS1100022I1 (hu) 2017-04-28

Similar Documents

Publication Publication Date Title
BE2011C027I2 (es)
RU2010139958A (ru) Стабилизированная фармацевтическая композиция, cодержащая доцетаксель
FR18C1027I1 (fr) Composition fongicide contenant un derive d'amide d'acide
EP1689406A4 (en) HETEROCYCLIC INHIBITORS OF MEK AND METHOD FOR THEIR APPLICATION
NO20044406L (no) Stabilisert flytende farmasoytisk sammensetning samt fremgangsmate for a oke stabiliteten av IL-2
EP1808083A4 (en) FORMULATION OF SWEETENER
CY1112401T1 (el) Παραγωγα πυριδαζινης
ATE532797T1 (de) Polymerisierbare zusammensetzungen enthaltend salze aus barbitursäure-derivaten
BR0206580A (pt) Composição farmacêutica tendo tendência reduzida para cristalização de droga
RU2011101713A (ru) Фармацевтическая композиция
CY1116189T1 (el) Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονη
IS8231A (is) Lyfjafræðilega gagnleg sölt karboxýlsýruafleiða
DK1459739T3 (da) Ikke-hydroskopiske farmaceutiske sammensætninger indeholdende ikke-hydratiserede quinolin-carboxylsyrer
DE602004009573D1 (de) Herstellung von 5-methyl-dihydrofuran-2-on aus levulinsäure in superkritischen medien
EA201490127A1 (ru) Офтальмологический раствор, содержащий гиалуроновую кислоту или ее соль и пропиленгликоль
RU2012117141A (ru) Композиции олопатадина и способы их применения
MA30600B1 (fr) Formulation medicamenteuse aqueuse d'acide 4-[((4-carboxybutyl)-{2-[(4-phenethyl-benzyl)oxy]-phenethyl}amino)methyl]benzoique.
IL174248A0 (en) Alkyl carboxylic acid derivatives and pharmaceutical compositions containing the same
WO2015087267A3 (en) Stable bromfenac ophthalmic solution
EP2284211A4 (en) WATER-CONTAINING EMULSION WITH AN A-OLEFIN - / (METH) ACRYLATE COPOLYMER AND METHOD FOR THE PRODUCTION THEREOF
RU2007142498A (ru) Фармацевтически активные диазепаны
DK1485084T3 (da) Anvendelse af et L-ascorbinsyresalt til at fremstille et farmaceutisk præparat til oftalmisk topisk anvendelse, der er i stand til at forbedre niveauet af L-ascorbinsyre i öjet
FR2933002B1 (fr) Solution absorbante contenant un inhibiteur de degradation soufre derive d'un acide amine et methode pour limiter la degradation d'une solution absorbante
EP1493819A4 (en) METHOD FOR PRODUCING EITHER OPTICALLY ACTIVE N-SUBSTITUTED BETA-AMINOIC ACID AND AN OPTICALLY ACTIVE N-SUBSTITUTED BETA-AMINO-ETHER OR AN OPTICALLY ACTIVE N-SUBSTITUTED 2-HOMOPIPECOLIC ACID AND AN OPTICALLY ACTIVE N-SUBSTITUTED 2-HOMOPIPECOLIC ACID ASSAY
EP1699448A4 (en) PROCESS FOR THE ADMINISTRATION OF 3,3,14,14-TETRAMETHYL-HEXADECANE-1,16-DIONIC ACID