ATA150594A - Verfahren zur kristallisation von iopamidol - Google Patents

Verfahren zur kristallisation von iopamidol

Info

Publication number: ATA150594A
Authority: AT; Austria
Prior art keywords: iopamidol; crystallizing; crystallizing iopamidol
Prior art date: 1993-07-30

Application number

AT0150594A

Other languages

English (en)

Other versions

AT404832B (de

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-30

Filing date

1994-07-29

Publication date

1998-07-15

1993-07-30 Priority claimed from ITMI931720A external-priority patent/IT1257001B/it

1994-04-20 Priority claimed from IT000760 external-priority patent/IT1269339B/it

1994-07-29 Application filed by Zambon Spa filed Critical Zambon Spa

1998-07-15 Publication of ATA150594A publication Critical patent/ATA150594A/de

1999-03-25 Application granted granted Critical

1999-03-25 Publication of AT404832B publication Critical patent/AT404832B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT0150594A 1993-07-30 1994-07-29 Verfahren zur kristallisation von iopamidol AT404832B (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITMI931720A IT1257001B (it)	1993-07-30	1993-07-30	Processo per la cristalizzazione dello iopamidolo
IT000760 IT1269339B (it)	1994-04-20	1994-04-20	Processo per la cristallizzazione dello iopamidolo

Publications (2)

Publication Number	Publication Date
ATA150594A true ATA150594A (de)	1998-07-15
AT404832B AT404832B (de)	1999-03-25

Family

ID=26331032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0150594A AT404832B (de)	1993-07-30	1994-07-29	Verfahren zur kristallisation von iopamidol

Country Status (29)

Country	Link
US (3)	US5571941A (de)
JP (1)	JP3299045B2 (de)
KR (1)	KR100355211B1 (de)
CN (1)	CN1035940C (de)
AT (1)	AT404832B (de)
AU (1)	AU690138B2 (de)
BE (1)	BE1008403A4 (de)
CA (1)	CA2128942C (de)
CH (1)	CH686783A5 (de)
CZ (1)	CZ289300B6 (de)
DE (1)	DE4426818A1 (de)
DK (1)	DK172074B1 (de)
ES (1)	ES2102312B1 (de)
FI (1)	FI960400A7 (de)
FR (1)	FR2708601B1 (de)
GB (1)	GB2280436B (de)
GR (1)	GR940100366A (de)
HU (1)	HU217023B (de)
IE (1)	IE80675B1 (de)
IL (1)	IL110391A (de)
NL (1)	NL194272C (de)
NO (1)	NO304226B1 (de)
NZ (1)	NZ271632A (de)
PT (1)	PT101554B (de)
RU (1)	RU2135462C1 (de)
SE (1)	SE9402595L (de)
SI (1)	SI9420046B (de)
WO (1)	WO1995004031A1 (de)
ZA (1)	ZA945472B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL110391A (en)	1993-07-30	1998-12-06	Zambon Spa	Process for the crystallization of iopamidol
US6310243B1 (en) *	1994-09-23	2001-10-30	Nycomed Imaging As	Iodinated x-ray contrast media
PT101720A (pt) *	1995-06-08	1997-01-31	Hovione Sociedade Quimica S A	Processo para a purificacao e cristalizacao de iopamidol
WO1997002235A1 (en) *	1995-07-04	1997-01-23	Recordati S.A. Chemical And Pharmaceutical Company	A process for preparing iopamidol by using a c1-c5 monoalkylether of a c2-c10 alkylen-glycol
CA2204734C (en) *	1995-09-08	2009-12-29	Marina Mauro	Process for the crystallization from water of (s)-n,n'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide
PT101919B (pt) *	1996-09-30	2000-01-31	Hovione Sociedade Quimica Sa	Um processo para a purificacao de tohexol
DE966428T1 (de) *	1997-02-11	2000-06-29	Bracco International B.V., Amsterdam	Verfahren zur kritallisation von (s)-n-n'-bis [2-hydroxy-1-(hydroxymethyl) ethyl]-5-[(2-hydroxy-1-xopropyl) amino]-2,4,6-trirodo-1,3-benzoldicarboxamid aus linearem oder verzweigtem (c5-c6) alkohol oder gemischen davon
GB9720969D0 (en) *	1997-10-02	1997-12-03	Nycomed Imaging As	Process
KR20000031642A (ko) *	1998-11-09	2000-06-05	강재헌	이오파미돌의 결정화 방법
US6265610B1 (en)	1999-01-12	2001-07-24	The University Of North Carolina At Chapel Hill	Contrast media for angiography
US6803485B2 (en)	1999-02-26	2004-10-12	Bracco Imaging S.P.A.	Process for the preparation of iopamidol
IT1319671B1 (it)	2000-12-01	2003-10-23	Bracco Spa	Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino)
NO20043305D0 (no) *	2004-08-09	2004-08-09	Amersham Health As	Preparation of lodixanol
DE102005059191B4 (de) *	2005-12-05	2008-02-07	Bayer Schering Pharma Ag	Verfahren zur Rückgewinnung von für pharmazeutische Zwecke geeignetem Iopromid aus Mutterlaugen
KR100976097B1 (ko)	2008-12-05	2010-08-16	주식회사 대웅제약	이오프로마이드의 ｚ 이성체를 선택적으로 결정화하는 방법
KR20120028867A (ko) *	2009-04-02	2012-03-23	알러간, 인코포레이티드	프로스타글란딘 ｅ 수용체 길항제
WO2012136813A2 (en)	2011-04-07	2012-10-11	Universitetet I Oslo	Agents for medical radar diagnosis
DE102012104679A1 (de)	2011-05-30	2012-12-06	Westfälische Wilhelms-Universität Münster	Biotechnologische konversion von glycerin zu 2-amino-1,3-propandiol (serinol) in rekombinanten escherichia coli
CN104854080B (zh)	2012-12-19	2018-07-03	通用电气医疗集团股份有限公司	X-射线造影剂的纯化
KR102128423B1 (ko) *	2018-09-17	2020-07-01	(주)유케이케미팜	조영제 이오메프롤의 제조방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH608189A5 (de) *	1974-12-13	1978-12-29	Savac Ag
GB1548594A (en) *	1976-06-11	1979-07-18	Nyegaard & Co As	Triiodoisophthalic acid amides
IT1193211B (it) *	1979-08-09	1988-06-15	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
DE3150916A1 (de) *	1981-12-18	1983-06-30	Schering Ag, 1000 Berlin Und 4619 Bergkamen	N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
US5204086A (en) *	1982-10-01	1993-04-20	Nycomed Imaging As	X-ray contrast agent
DE3873766T2 (de) *	1987-05-22	1993-02-11	Bracco Ind Chimica Spa	Herstellung von 5-acylamino-2,4,6-trijodo- oder tribromo-benzoesaeure-derivate.
IT1248741B (it) *	1991-02-26	1995-01-26	Bracco Spa	Processo di concentrazione e di purificazione di composti organici
IL110391A (en)	1993-07-30	1998-12-06	Zambon Spa	Process for the crystallization of iopamidol

1994
- 1994-07-20 IL IL11039194A patent/IL110391A/en not_active IP Right Cessation
- 1994-07-22 RU RU96105070A patent/RU2135462C1/ru active
- 1994-07-22 KR KR1019960700580A patent/KR100355211B1/ko not_active Expired - Lifetime
- 1994-07-22 WO PCT/EP1994/002415 patent/WO1995004031A1/en not_active Ceased
- 1994-07-22 AU AU75321/94A patent/AU690138B2/en not_active Expired
- 1994-07-22 NZ NZ271632A patent/NZ271632A/en not_active IP Right Cessation
- 1994-07-22 CN CN94192930A patent/CN1035940C/zh not_active Expired - Lifetime
- 1994-07-22 GR GR940100366A patent/GR940100366A/el unknown
- 1994-07-22 SI SI9420046A patent/SI9420046B/sl unknown
- 1994-07-22 FI FI960400A patent/FI960400A7/fi not_active Application Discontinuation
- 1994-07-22 HU HU9600191A patent/HU217023B/hu unknown
- 1994-07-25 GB GB9414912A patent/GB2280436B/en not_active Expired - Lifetime
- 1994-07-25 ZA ZA945472A patent/ZA945472B/xx unknown
- 1994-07-26 CH CH02354/94A patent/CH686783A5/it not_active IP Right Cessation
- 1994-07-26 NL NL9401229A patent/NL194272C/nl not_active IP Right Cessation
- 1994-07-26 PT PT101554A patent/PT101554B/pt not_active IP Right Cessation
- 1994-07-26 FR FR9409238A patent/FR2708601B1/fr not_active Expired - Lifetime
- 1994-07-27 CA CA002128942A patent/CA2128942C/en not_active Expired - Lifetime
- 1994-07-28 DE DE4426818A patent/DE4426818A1/de not_active Ceased
- 1994-07-29 IE IE940609A patent/IE80675B1/en not_active IP Right Cessation
- 1994-07-29 BE BE9400717A patent/BE1008403A4/fr not_active IP Right Cessation
- 1994-07-29 SE SE9402595A patent/SE9402595L/xx not_active Application Discontinuation
- 1994-07-29 CZ CZ19941831A patent/CZ289300B6/cs not_active IP Right Cessation
- 1994-07-29 AT AT0150594A patent/AT404832B/de not_active IP Right Cessation
- 1994-07-29 DK DK089294A patent/DK172074B1/da not_active IP Right Cessation
- 1994-07-29 US US08/281,985 patent/US5571941A/en not_active Ceased
- 1994-07-29 ES ES09401679A patent/ES2102312B1/es not_active Expired - Fee Related
- 1994-07-29 JP JP17811594A patent/JP3299045B2/ja not_active Expired - Lifetime
1996
- 1996-01-29 NO NO960376A patent/NO304226B1/no not_active IP Right Cessation
1997
- 1997-02-07 US US08/797,610 patent/USRE36433E/en not_active Expired - Lifetime
1998
- 1998-08-25 US US09/139,894 patent/US6506938B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK89294A (da)	1995-01-31
IL110391A (en)	1998-12-06
AT404832B (de)	1999-03-25
IE80675B1 (en)	1998-11-18
FR2708601B1 (fr)	1995-12-08
KR100355211B1 (ko)	2003-04-10
NZ271632A (en)	1997-07-27
HU9600191D0 (en)	1996-11-28
GB2280436A (en)	1995-02-01
NL194272C (nl)	2001-11-05
CZ289300B6 (cs)	2001-12-12
CA2128942A1 (en)	1995-01-31
FI960400L (fi)	1996-01-29
NL9401229A (nl)	1995-02-16
USRE36433E (en)	1999-12-07
FR2708601A1 (fr)	1995-02-10
CN1128020A (zh)	1996-07-31
RU2135462C1 (ru)	1999-08-27
NO304226B1 (no)	1998-11-16
GB2280436B (en)	1997-08-13
JPH07145125A (ja)	1995-06-06
WO1995004031A1 (en)	1995-02-09
CZ183194A3 (en)	1995-02-15
KR960703842A (ko)	1996-08-31
NO960376D0 (no)	1996-01-29
SI9420046A (en)	1996-10-31
SE9402595L (sv)	1995-01-31
NL194272B (nl)	2001-07-02
HU217023B (hu)	1999-11-29
NO960376L (no)	1996-01-29
CN1035940C (zh)	1997-09-24
ES2102312A1 (es)	1997-07-16
IL110391A0 (en)	1994-10-21
SE9402595D0 (sv)	1994-07-29
CA2128942C (en)	2003-07-15
DE4426818A1 (de)	1995-02-02
DK172074B1 (da)	1997-10-13
HUP9774567A2 (en)	1997-01-28
GR940100366A (en)	1996-03-31
US5571941A (en)	1996-11-05
AU690138B2 (en)	1998-04-23
FI960400A0 (fi)	1996-01-29
PT101554B (pt)	2000-01-31
FI960400A7 (fi)	1996-01-29
AU7532194A (en)	1995-02-28
IE940609A1 (en)	1995-02-08
BE1008403A4 (fr)	1996-05-07
US6506938B1 (en)	2003-01-14
CH686783A5 (it)	1996-06-28
PT101554A (pt)	1995-05-04
ES2102312B1 (es)	1998-04-01
SI9420046B (sl)	2003-10-31
ZA945472B (en)	1995-03-03
JP3299045B2 (ja)	2002-07-08
GB9414912D0 (en)	1994-09-14

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Legal Events

Date	Code	Title	Description
2002-03-15	REN	Ceased due to non-payment of the annual fee
2014-10-15	MK07	Expiry	Effective date: 20140729