DK89294A - Fremgangsmåde til krystallisation af iodamidol - Google Patents

Fremgangsmåde til krystallisation af iodamidol

Info

Publication number: DK89294A
Authority: DK; Denmark
Prior art keywords: iodamidol; crystallization
Prior art date: 1993-07-30

Application number

DK089294A

Other languages

English (en)

Other versions

DK172074B1 (da

Inventor

Marco Villa

Maurizio Paiocchi

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-30

Filing date

1994-07-29

Publication date

1995-01-31

1993-07-30 Priority claimed from ITMI931720A external-priority patent/IT1257001B/it

1994-04-20 Priority claimed from IT000760 external-priority patent/IT1269339B/it

1994-07-29 Application filed by Zambon Spa filed Critical Zambon Spa

1995-01-31 Publication of DK89294A publication Critical patent/DK89294A/da

1997-10-13 Application granted granted Critical

1997-10-13 Publication of DK172074B1 publication Critical patent/DK172074B1/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK089294A 1993-07-30 1994-07-29 Fremgangsmåde til krystallisation af iopamidol og anvendelse af butanol dertil DK172074B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
ITMI931720		1993-07-30
ITMI931720A IT1257001B (it)	1993-07-30	1993-07-30	Processo per la cristalizzazione dello iopamidolo
ITMI940760		1994-04-20
IT000760 IT1269339B (it)	1994-04-20	1994-04-20	Processo per la cristallizzazione dello iopamidolo

Publications (2)

Publication Number	Publication Date
DK89294A true DK89294A (da)	1995-01-31
DK172074B1 DK172074B1 (da)	1997-10-13

Family

ID=26331032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK089294A DK172074B1 (da)	1993-07-30	1994-07-29	Fremgangsmåde til krystallisation af iopamidol og anvendelse af butanol dertil

Country Status (29)

Country	Link
US (3)	US5571941A (da)
JP (1)	JP3299045B2 (da)
KR (1)	KR100355211B1 (da)
CN (1)	CN1035940C (da)
AT (1)	AT404832B (da)
AU (1)	AU690138B2 (da)
BE (1)	BE1008403A4 (da)
CA (1)	CA2128942C (da)
CH (1)	CH686783A5 (da)
CZ (1)	CZ289300B6 (da)
DE (1)	DE4426818A1 (da)
DK (1)	DK172074B1 (da)
ES (1)	ES2102312B1 (da)
FI (1)	FI960400L (da)
FR (1)	FR2708601B1 (da)
GB (1)	GB2280436B (da)
GR (1)	GR940100366A (da)
HU (1)	HU217023B (da)
IE (1)	IE80675B1 (da)
IL (1)	IL110391A (da)
NL (1)	NL194272C (da)
NO (1)	NO304226B1 (da)
NZ (1)	NZ271632A (da)
PT (1)	PT101554B (da)
RU (1)	RU2135462C1 (da)
SE (1)	SE9402595L (da)
SI (1)	SI9420046B (da)
WO (1)	WO1995004031A1 (da)
ZA (1)	ZA945472B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL110391A (en)	1993-07-30	1998-12-06	Zambon Spa	Process for the crystallization of iopamidol
US6310243B1 (en) *	1994-09-23	2001-10-30	Nycomed Imaging As	Iodinated x-ray contrast media
PT101720A (pt) *	1995-06-08	1997-01-31	Hovione Sociedade Quimica S A	Processo para a purificacao e cristalizacao de iopamidol
EP0842141A1 (en) *	1995-07-04	1998-05-20	RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY	A process for preparing iopamidol by using a c1-c5 monoalkylether of a c2-c10 alkylen-glycol
BR9606624A (pt) *	1995-09-08	1997-11-11	Bracco Int Bv	Processo para a cristalização de (s)-n,n'-bisÚ2-hidróxi-1-(hidroximetil)etil¾-5-Ú(2-hidróxi-1-oxopropil)amino¾-2,4,6-triiodo-1,3-benzonodicar-boxamida a partir de água
PT101919B (pt) *	1996-09-30	2000-01-31	Hovione Sociedade Quimica Sa	Um processo para a purificacao de tohexol
CZ299420B6 (cs) *	1997-02-11	2008-07-23	Bracco International B. V.	Zpusob krystalizace iopamidolu
GB9720969D0 (en) *	1997-10-02	1997-12-03	Nycomed Imaging As	Process
KR20000031642A (ko) *	1998-11-09	2000-06-05	강재헌	이오파미돌의 결정화 방법
US6265610B1 (en)	1999-01-12	2001-07-24	The University Of North Carolina At Chapel Hill	Contrast media for angiography
US6803485B2 (en)	1999-02-26	2004-10-12	Bracco Imaging S.P.A.	Process for the preparation of iopamidol
IT1319671B1 (it)	2000-12-01	2003-10-23	Bracco Spa	Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino)
NO20043305D0 (no) *	2004-08-09	2004-08-09	Amersham Health As	Preparation of lodixanol
DE102005059191B4 (de) *	2005-12-05	2008-02-07	Bayer Schering Pharma Ag	Verfahren zur Rückgewinnung von für pharmazeutische Zwecke geeignetem Iopromid aus Mutterlaugen
KR100976097B1 (ko) *	2008-12-05	2010-08-16	주식회사 대웅제약	이오프로마이드의 ｚ 이성체를 선택적으로 결정화하는 방법
EP2414367B1 (en) *	2009-04-02	2014-08-13	Allergan, Inc.	Prostaglandin e receptor antagonists
WO2012136813A2 (en)	2011-04-07	2012-10-11	Universitetet I Oslo	Agents for medical radar diagnosis
DE102012104679A1 (de)	2011-05-30	2012-12-06	Westfälische Wilhelms-Universität Münster	Biotechnologische konversion von glycerin zu 2-amino-1,3-propandiol (serinol) in rekombinanten escherichia coli
JP6342421B2 (ja)	2012-12-19	2018-06-13	ジーイー・ヘルスケア・アクスイェ・セルスカプ	Ｘ線造影剤の精製
KR102128423B1 (ko) *	2018-09-17	2020-07-01	(주)유케이케미팜	조영제 이오메프롤의 제조방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH608189A5 (da) *	1974-12-13	1978-12-29	Savac Ag
GB1548594A (en) *	1976-06-11	1979-07-18	Nyegaard & Co As	Triiodoisophthalic acid amides
IT1193211B (it) *	1979-08-09	1988-06-15	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
DE3150916A1 (de) *	1981-12-18	1983-06-30	Schering Ag, 1000 Berlin Und 4619 Bergkamen	N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
US5204086A (en) *	1982-10-01	1993-04-20	Nycomed Imaging As	X-ray contrast agent
WO1988009328A1 (en) *	1987-05-22	1988-12-01	Bracco Industria Chimica S.P.A.	Preparation of 5-acylamino-2,4,6-triiodo- or tribromo-benzoic acid derivatives
IT1248741B (it) *	1991-02-26	1995-01-26	Bracco Spa	Processo di concentrazione e di purificazione di composti organici
IL110391A (en)	1993-07-30	1998-12-06	Zambon Spa	Process for the crystallization of iopamidol

1994
- 1994-07-20 IL IL11039194A patent/IL110391A/en not_active IP Right Cessation
- 1994-07-22 FI FI960400A patent/FI960400L/fi not_active Application Discontinuation
- 1994-07-22 NZ NZ271632A patent/NZ271632A/en not_active IP Right Cessation
- 1994-07-22 WO PCT/EP1994/002415 patent/WO1995004031A1/en not_active Ceased
- 1994-07-22 SI SI9420046A patent/SI9420046B/sl unknown
- 1994-07-22 KR KR1019960700580A patent/KR100355211B1/ko not_active Expired - Lifetime
- 1994-07-22 RU RU96105070A patent/RU2135462C1/ru active
- 1994-07-22 HU HU9600191A patent/HU217023B/hu unknown
- 1994-07-22 AU AU75321/94A patent/AU690138B2/en not_active Expired
- 1994-07-22 CN CN94192930A patent/CN1035940C/zh not_active Expired - Lifetime
- 1994-07-22 GR GR940100366A patent/GR940100366A/el unknown
- 1994-07-25 ZA ZA945472A patent/ZA945472B/xx unknown
- 1994-07-25 GB GB9414912A patent/GB2280436B/en not_active Expired - Lifetime
- 1994-07-26 FR FR9409238A patent/FR2708601B1/fr not_active Expired - Lifetime
- 1994-07-26 PT PT101554A patent/PT101554B/pt not_active IP Right Cessation
- 1994-07-26 NL NL9401229A patent/NL194272C/nl not_active IP Right Cessation
- 1994-07-26 CH CH02354/94A patent/CH686783A5/it not_active IP Right Cessation
- 1994-07-27 CA CA002128942A patent/CA2128942C/en not_active Expired - Lifetime
- 1994-07-28 DE DE4426818A patent/DE4426818A1/de not_active Ceased
- 1994-07-29 IE IE940609A patent/IE80675B1/en not_active IP Right Cessation
- 1994-07-29 US US08/281,985 patent/US5571941A/en not_active Ceased
- 1994-07-29 BE BE9400717A patent/BE1008403A4/fr not_active IP Right Cessation
- 1994-07-29 SE SE9402595A patent/SE9402595L/xx not_active Application Discontinuation
- 1994-07-29 AT AT0150594A patent/AT404832B/de not_active IP Right Cessation
- 1994-07-29 DK DK089294A patent/DK172074B1/da not_active IP Right Cessation
- 1994-07-29 ES ES09401679A patent/ES2102312B1/es not_active Expired - Fee Related
- 1994-07-29 JP JP17811594A patent/JP3299045B2/ja not_active Expired - Lifetime
- 1994-07-29 CZ CZ19941831A patent/CZ289300B6/cs not_active IP Right Cessation
1996
- 1996-01-29 NO NO960376A patent/NO304226B1/no not_active IP Right Cessation
1997
- 1997-02-07 US US08/797,610 patent/USRE36433E/en not_active Expired - Lifetime
1998
- 1998-08-25 US US09/139,894 patent/US6506938B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
GB9414912D0 (en)	1994-09-14
FI960400A7 (fi)	1996-01-29
JPH07145125A (ja)	1995-06-06
CZ183194A3 (en)	1995-02-15
HUP9774567A2 (en)	1997-01-28
DK172074B1 (da)	1997-10-13
PT101554A (pt)	1995-05-04
US6506938B1 (en)	2003-01-14
IL110391A0 (en)	1994-10-21
FI960400A0 (fi)	1996-01-29
US5571941A (en)	1996-11-05
NL194272C (nl)	2001-11-05
ZA945472B (en)	1995-03-03
AU690138B2 (en)	1998-04-23
JP3299045B2 (ja)	2002-07-08
CN1128020A (zh)	1996-07-31
NO960376L (no)	1996-01-29
WO1995004031A1 (en)	1995-02-09
KR960703842A (ko)	1996-08-31
IE940609A1 (en)	1995-02-08
BE1008403A4 (fr)	1996-05-07
CH686783A5 (it)	1996-06-28
NL194272B (nl)	2001-07-02
SE9402595D0 (sv)	1994-07-29
HU9600191D0 (en)	1996-11-28
IE80675B1 (en)	1998-11-18
DE4426818A1 (de)	1995-02-02
KR100355211B1 (ko)	2003-04-10
FR2708601A1 (fr)	1995-02-10
SI9420046B (sl)	2003-10-31
GB2280436A (en)	1995-02-01
GR940100366A (en)	1996-03-31
ES2102312A1 (es)	1997-07-16
GB2280436B (en)	1997-08-13
NO960376D0 (no)	1996-01-29
FI960400L (fi)	1996-01-29
CZ289300B6 (cs)	2001-12-12
RU2135462C1 (ru)	1999-08-27
SI9420046A (en)	1996-10-31
CN1035940C (zh)	1997-09-24
NZ271632A (en)	1997-07-27
AT404832B (de)	1999-03-25
AU7532194A (en)	1995-02-28
SE9402595L (sv)	1995-01-31
NO304226B1 (no)	1998-11-16
HU217023B (hu)	1999-11-29
USRE36433E (en)	1999-12-07
CA2128942A1 (en)	1995-01-31
CA2128942C (en)	2003-07-15
PT101554B (pt)	2000-01-31
ATA150594A (de)	1998-07-15
ES2102312B1 (es)	1998-04-01
NL9401229A (nl)	1995-02-16
IL110391A (en)	1998-12-06
FR2708601B1 (fr)	1995-12-08

Publication	Publication Date	Title
DK89294A (da)	1995-01-31	Fremgangsmåde til krystallisation af iodamidol
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DK0658083T3 (da)	1997-12-22	Fremgangsmåde til dekontaminering af fødevarer
DK0689570T3 (da)	1999-02-08	Fremgangsmåde til fremstilling af gelatine
DK0937068T3 (da)	2002-05-21	Fremgangsmåde til krystallisation af losartan
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DK0648738T3 (da)	1997-06-16	Fremgangsmåde til fremstilling af acetoacetarylamider
DK0648748T3 (da)	1997-10-13	Fremgangsmåde til fremstilling af 5-acetoacetylaminobenzimidazolon-2
DK16093A (da)	1994-08-13	Fremgangsmåde til fremstilling af organiske isocyanater
DK0635490T3 (da)	1997-06-02	Fremgangsmåde til fremstilling af N-ethylcarbazol
DK53792D0 (da)	1992-04-24	Fremgangsmaade til fremstilling af proteiner
DE69333521D1 (de)	2004-06-17	Verfahren zur Kristallisierung von N2-((S)-1-ethoxycarbonyl-3-phenylpropyl)-N6-trifluoroacetyl-L-lysyl-L-prolin
DK133793D0 (da)	1993-11-30	Fremgangsmaade til dehydrogenering af carbonhydrider
DK0519512T3 (da)	1996-03-18	Mikrobiologisk fremgangsmåde til fremstilling af 5-hydroxypyrazincarboxylsyre
DK0863874T3 (da)	2001-01-29	Fremgangsmåde til fremstilling af dioxoazabicyclohexaner

Legal Events

Date	Code	Title	Description
1997-10-13	B1	Patent granted (law 1993)
2014-08-04	PUP	Patent expired	Expiry date: 20140729