NO960376L - Fremgangsmåte for krystallisering av iopamidol - Google Patents
Fremgangsmåte for krystallisering av iopamidolInfo
- Publication number
- NO960376L NO960376L NO960376A NO960376A NO960376L NO 960376 L NO960376 L NO 960376L NO 960376 A NO960376 A NO 960376A NO 960376 A NO960376 A NO 960376A NO 960376 L NO960376 L NO 960376L
- Authority
- NO
- Norway
- Prior art keywords
- iopamidol
- crystallization
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI931720A IT1257001B (it) | 1993-07-30 | 1993-07-30 | Processo per la cristalizzazione dello iopamidolo |
| IT000760 IT1269339B (it) | 1994-04-20 | 1994-04-20 | Processo per la cristallizzazione dello iopamidolo |
| PCT/EP1994/002415 WO1995004031A1 (en) | 1993-07-30 | 1994-07-22 | Process for the crystallization of iopamidol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO960376D0 NO960376D0 (no) | 1996-01-29 |
| NO960376L true NO960376L (no) | 1996-01-29 |
| NO304226B1 NO304226B1 (no) | 1998-11-16 |
Family
ID=26331032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO960376A NO304226B1 (no) | 1993-07-30 | 1996-01-29 | FremgangsmÕte for krystallisering av iopamidol, samt anvendelse av butanoler ved krystalliseringen |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US5571941A (no) |
| JP (1) | JP3299045B2 (no) |
| KR (1) | KR100355211B1 (no) |
| CN (1) | CN1035940C (no) |
| AT (1) | AT404832B (no) |
| AU (1) | AU690138B2 (no) |
| BE (1) | BE1008403A4 (no) |
| CA (1) | CA2128942C (no) |
| CH (1) | CH686783A5 (no) |
| CZ (1) | CZ289300B6 (no) |
| DE (1) | DE4426818A1 (no) |
| DK (1) | DK172074B1 (no) |
| ES (1) | ES2102312B1 (no) |
| FI (1) | FI960400A7 (no) |
| FR (1) | FR2708601B1 (no) |
| GB (1) | GB2280436B (no) |
| GR (1) | GR940100366A (no) |
| HU (1) | HU217023B (no) |
| IE (1) | IE80675B1 (no) |
| IL (1) | IL110391A (no) |
| NL (1) | NL194272C (no) |
| NO (1) | NO304226B1 (no) |
| NZ (1) | NZ271632A (no) |
| PT (1) | PT101554B (no) |
| RU (1) | RU2135462C1 (no) |
| SE (1) | SE9402595L (no) |
| SI (1) | SI9420046B (no) |
| WO (1) | WO1995004031A1 (no) |
| ZA (1) | ZA945472B (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL110391A (en) | 1993-07-30 | 1998-12-06 | Zambon Spa | Process for the crystallization of iopamidol |
| US6310243B1 (en) * | 1994-09-23 | 2001-10-30 | Nycomed Imaging As | Iodinated x-ray contrast media |
| PT101720A (pt) * | 1995-06-08 | 1997-01-31 | Hovione Sociedade Quimica S A | Processo para a purificacao e cristalizacao de iopamidol |
| WO1997002235A1 (en) * | 1995-07-04 | 1997-01-23 | Recordati S.A. Chemical And Pharmaceutical Company | A process for preparing iopamidol by using a c1-c5 monoalkylether of a c2-c10 alkylen-glycol |
| CA2204734C (en) * | 1995-09-08 | 2009-12-29 | Marina Mauro | Process for the crystallization from water of (s)-n,n'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide |
| PT101919B (pt) * | 1996-09-30 | 2000-01-31 | Hovione Sociedade Quimica Sa | Um processo para a purificacao de tohexol |
| DE966428T1 (de) * | 1997-02-11 | 2000-06-29 | Bracco International B.V., Amsterdam | Verfahren zur kritallisation von (s)-n-n'-bis [2-hydroxy-1-(hydroxymethyl) ethyl]-5-[(2-hydroxy-1-xopropyl) amino]-2,4,6-trirodo-1,3-benzoldicarboxamid aus linearem oder verzweigtem (c5-c6) alkohol oder gemischen davon |
| GB9720969D0 (en) * | 1997-10-02 | 1997-12-03 | Nycomed Imaging As | Process |
| KR20000031642A (ko) * | 1998-11-09 | 2000-06-05 | 강재헌 | 이오파미돌의 결정화 방법 |
| US6265610B1 (en) | 1999-01-12 | 2001-07-24 | The University Of North Carolina At Chapel Hill | Contrast media for angiography |
| US6803485B2 (en) | 1999-02-26 | 2004-10-12 | Bracco Imaging S.P.A. | Process for the preparation of iopamidol |
| IT1319671B1 (it) | 2000-12-01 | 2003-10-23 | Bracco Spa | Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino) |
| NO20043305D0 (no) * | 2004-08-09 | 2004-08-09 | Amersham Health As | Preparation of lodixanol |
| DE102005059191B4 (de) * | 2005-12-05 | 2008-02-07 | Bayer Schering Pharma Ag | Verfahren zur Rückgewinnung von für pharmazeutische Zwecke geeignetem Iopromid aus Mutterlaugen |
| KR100976097B1 (ko) | 2008-12-05 | 2010-08-16 | 주식회사 대웅제약 | 이오프로마이드의 z 이성체를 선택적으로 결정화하는 방법 |
| KR20120028867A (ko) * | 2009-04-02 | 2012-03-23 | 알러간, 인코포레이티드 | 프로스타글란딘 e 수용체 길항제 |
| WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
| DE102012104679A1 (de) | 2011-05-30 | 2012-12-06 | Westfälische Wilhelms-Universität Münster | Biotechnologische konversion von glycerin zu 2-amino-1,3-propandiol (serinol) in rekombinanten escherichia coli |
| CN104854080B (zh) | 2012-12-19 | 2018-07-03 | 通用电气医疗集团股份有限公司 | X-射线造影剂的纯化 |
| KR102128423B1 (ko) * | 2018-09-17 | 2020-07-01 | (주)유케이케미팜 | 조영제 이오메프롤의 제조방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608189A5 (no) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
| GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
| IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
| DE3150916A1 (de) * | 1981-12-18 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel" |
| US5204086A (en) * | 1982-10-01 | 1993-04-20 | Nycomed Imaging As | X-ray contrast agent |
| DE3873766T2 (de) * | 1987-05-22 | 1993-02-11 | Bracco Ind Chimica Spa | Herstellung von 5-acylamino-2,4,6-trijodo- oder tribromo-benzoesaeure-derivate. |
| IT1248741B (it) * | 1991-02-26 | 1995-01-26 | Bracco Spa | Processo di concentrazione e di purificazione di composti organici |
| IL110391A (en) | 1993-07-30 | 1998-12-06 | Zambon Spa | Process for the crystallization of iopamidol |
-
1994
- 1994-07-20 IL IL11039194A patent/IL110391A/en not_active IP Right Cessation
- 1994-07-22 RU RU96105070A patent/RU2135462C1/ru active
- 1994-07-22 KR KR1019960700580A patent/KR100355211B1/ko not_active Expired - Lifetime
- 1994-07-22 WO PCT/EP1994/002415 patent/WO1995004031A1/en not_active Ceased
- 1994-07-22 AU AU75321/94A patent/AU690138B2/en not_active Expired
- 1994-07-22 NZ NZ271632A patent/NZ271632A/en not_active IP Right Cessation
- 1994-07-22 CN CN94192930A patent/CN1035940C/zh not_active Expired - Lifetime
- 1994-07-22 GR GR940100366A patent/GR940100366A/el unknown
- 1994-07-22 SI SI9420046A patent/SI9420046B/sl unknown
- 1994-07-22 FI FI960400A patent/FI960400A7/fi not_active Application Discontinuation
- 1994-07-22 HU HU9600191A patent/HU217023B/hu unknown
- 1994-07-25 GB GB9414912A patent/GB2280436B/en not_active Expired - Lifetime
- 1994-07-25 ZA ZA945472A patent/ZA945472B/xx unknown
- 1994-07-26 CH CH02354/94A patent/CH686783A5/it not_active IP Right Cessation
- 1994-07-26 NL NL9401229A patent/NL194272C/nl not_active IP Right Cessation
- 1994-07-26 PT PT101554A patent/PT101554B/pt not_active IP Right Cessation
- 1994-07-26 FR FR9409238A patent/FR2708601B1/fr not_active Expired - Lifetime
- 1994-07-27 CA CA002128942A patent/CA2128942C/en not_active Expired - Lifetime
- 1994-07-28 DE DE4426818A patent/DE4426818A1/de not_active Ceased
- 1994-07-29 IE IE940609A patent/IE80675B1/en not_active IP Right Cessation
- 1994-07-29 BE BE9400717A patent/BE1008403A4/fr not_active IP Right Cessation
- 1994-07-29 SE SE9402595A patent/SE9402595L/xx not_active Application Discontinuation
- 1994-07-29 CZ CZ19941831A patent/CZ289300B6/cs not_active IP Right Cessation
- 1994-07-29 AT AT0150594A patent/AT404832B/de not_active IP Right Cessation
- 1994-07-29 DK DK089294A patent/DK172074B1/da not_active IP Right Cessation
- 1994-07-29 US US08/281,985 patent/US5571941A/en not_active Ceased
- 1994-07-29 ES ES09401679A patent/ES2102312B1/es not_active Expired - Fee Related
- 1994-07-29 JP JP17811594A patent/JP3299045B2/ja not_active Expired - Lifetime
-
1996
- 1996-01-29 NO NO960376A patent/NO304226B1/no not_active IP Right Cessation
-
1997
- 1997-02-07 US US08/797,610 patent/USRE36433E/en not_active Expired - Lifetime
-
1998
- 1998-08-25 US US09/139,894 patent/US6506938B1/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |