AR034277A1 - Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccion - Google Patents
Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccionInfo
- Publication number
- AR034277A1 AR034277A1 ARP010105391A ARP010105391A AR034277A1 AR 034277 A1 AR034277 A1 AR 034277A1 AR P010105391 A ARP010105391 A AR P010105391A AR P010105391 A ARP010105391 A AR P010105391A AR 034277 A1 AR034277 A1 AR 034277A1
- Authority
- AR
- Argentina
- Prior art keywords
- pantoprazol
- preparation
- injection
- liophilized
- pantoprazole
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Proceso para la producción de una preparación liofilizada que comprende 5-difluorometoxi-2-[(3,4-dimetoxi-2-pirimidinil)metilsulfinil]-1-H-bencimidazol (pantoprazol), una sal del mismo, un solvato de pantoprazol o una sal del mismo, que comprende liofilizar una solución acuosa de pantroprazol, una sal del mismo, un solvato de pantoprazol o una sal del mismo, ácido etilenodiaminotetraacético y/o una sal de adecuada del mismo, e hidróxido de sodio y/o carbonato de sodio.Se describe una preparación liofilizada de pantoprazol, así como una inyección obtenible por reconstitución de la preparación liofilizada de pantoprazol en un disolvente adecuado y un kit para inyección.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00125569 | 2000-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR034277A1 true AR034277A1 (es) | 2004-02-18 |
Family
ID=8170452
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010105391A AR034277A1 (es) | 2000-11-22 | 2001-11-19 | Proceso para la produccion de una preparacion liofilizada de pantoprazol, preparacion liofilizada de pantoprazol obtenida, inyeccion de pantoprazol obtenida por reconstitucion en un disolvente y kit de inyeccion |
| ARP130102967A AR092374A2 (es) | 2000-11-22 | 2013-08-21 | Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol) |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130102967A AR092374A2 (es) | 2000-11-22 | 2013-08-21 | Preparacion liofilizada de 5-difluorometoxi-2-[(3,4-dimetoxi-2-piridinil)metilsulfinil]-1h-bencimidazol (pantoprazol) |
Country Status (39)
| Country | Link |
|---|---|
| US (3) | US6780881B2 (es) |
| EP (2) | EP1339430B1 (es) |
| JP (1) | JP4886158B2 (es) |
| KR (2) | KR100910607B1 (es) |
| CN (1) | CN1250292C (es) |
| AR (2) | AR034277A1 (es) |
| AT (1) | ATE381946T1 (es) |
| AU (2) | AU2002216042B2 (es) |
| BG (1) | BG66329B1 (es) |
| BR (1) | BRPI0115483B8 (es) |
| CA (2) | CA2541946A1 (es) |
| CY (1) | CY1107896T1 (es) |
| CZ (1) | CZ304348B6 (es) |
| DE (1) | DE60132108T2 (es) |
| DK (1) | DK1339430T3 (es) |
| EA (1) | EA007602B1 (es) |
| EC (1) | ECSP034613A (es) |
| EE (1) | EE05236B1 (es) |
| ES (1) | ES2298295T3 (es) |
| GE (1) | GEP20053461B (es) |
| HR (1) | HRP20030410B1 (es) |
| HU (1) | HUP0303278A3 (es) |
| IL (2) | IL155601A0 (es) |
| IS (1) | IS2971B (es) |
| ME (1) | ME00556A (es) |
| MX (1) | MXPA03004548A (es) |
| MY (1) | MY137726A (es) |
| NO (1) | NO332937B1 (es) |
| NZ (1) | NZ525911A (es) |
| PE (1) | PE20020582A1 (es) |
| PL (1) | PL201188B1 (es) |
| PT (1) | PT1339430E (es) |
| RS (1) | RS52024B (es) |
| SI (1) | SI1339430T1 (es) |
| SK (1) | SK287993B6 (es) |
| TW (1) | TWI284041B (es) |
| UA (1) | UA80961C2 (es) |
| WO (1) | WO2002041919A1 (es) |
| ZA (1) | ZA200303593B (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
| US20050287231A1 (en) * | 2002-06-21 | 2005-12-29 | Nussen Kenneth H | Method and apparatus for oral hygiene products with green tea extract |
| CN1703198A (zh) * | 2002-10-25 | 2005-11-30 | 辉瑞产品公司 | 呈混悬剂形式的芳基杂环活性物质的贮库制剂 |
| WO2004099183A1 (en) * | 2003-05-06 | 2004-11-18 | Hetero Drugs Limited | Novel polymorphs of pantoprazole sodium |
| CL2004000983A1 (es) * | 2003-05-08 | 2005-03-04 | Altana Pharma Ag | Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y |
| WO2004100949A2 (en) * | 2003-05-19 | 2004-11-25 | Pliva-Istrazivanje I Razvoj D.O.O. | Solid-state forms of 5-(difluoromethoxy)-2-((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-1h-benzimidazole (pantoprazole) sodium aqua complexes |
| AR045258A1 (es) * | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
| WO2005070426A1 (en) * | 2004-01-27 | 2005-08-04 | Altana Pharma Ag | Freeze-dried (-)-pantoprazole preparation and (-)-pantoprazole injection |
| DE102004007854A1 (de) * | 2004-02-17 | 2005-09-01 | Hexal Ag | Stabile, wässrige Formulierung für Benzimidazole |
| US20060085924A1 (en) * | 2004-10-13 | 2006-04-27 | Gaelle Brun | Coloring composition comprising at least one pigment and at least one electrophilic cyanoacrylate monomer |
| CN1293879C (zh) * | 2005-01-20 | 2007-01-10 | 杭州华东医药集团生物工程研究所有限公司 | 泮托拉唑钠冻干粉针剂及其制备方法 |
| JP2009511481A (ja) * | 2005-10-06 | 2009-03-19 | オースペックス・ファーマシューティカルズ・インコーポレイテッド | 増強された治療特性を持つ、胃Ｈ＋，Ｋ＋−ＡＴＰａｓｅの重水素化阻害剤 |
| AR061155A1 (es) * | 2006-06-01 | 2008-08-06 | Combino Pharm Sl | Preparaciones liofilizadas de pantoprazol sodico para inyeccion |
| WO2008012310A1 (en) | 2006-07-26 | 2008-01-31 | Sandoz Ag | Caspofungin formulations |
| US7979200B2 (en) * | 2006-11-20 | 2011-07-12 | Lockheed Martin Corporation | Managing an air-ground communications network with air traffic control information |
| EP2106788A1 (en) * | 2008-04-04 | 2009-10-07 | Ipsen Pharma | Liquid and freeze dried formulations |
| CN101744777B (zh) * | 2009-12-30 | 2012-09-26 | 北京四环科宝制药有限公司 | 奥美拉唑钠冻干粉针剂及制备方法和检测方法 |
| CN101961309B (zh) * | 2010-09-15 | 2012-06-27 | 河南辅仁怀庆堂制药有限公司 | 注射用泮托拉唑钠配制工艺 |
| CN102000034B (zh) * | 2010-10-13 | 2011-12-21 | 江苏奥赛康药业股份有限公司 | 一种供注射用的s-泮托拉唑钠组合物及其制备方法 |
| CN102225063B (zh) * | 2011-05-10 | 2012-10-10 | 江苏奥赛康药业股份有限公司 | 一种供注射用的泮托拉唑钠组合物 |
| TR201108946A2 (tr) * | 2011-09-12 | 2012-04-24 | World Medicine İlaç Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Dondurularak kurutulmuş atp, vitamin b kompleksi preparatı ve enjeksiyonu. |
| CN110917130A (zh) * | 2012-06-27 | 2020-03-27 | 武田药品工业株式会社 | 用盐稳定的胺和有机酸的液体制剂 |
| CN104000786A (zh) * | 2013-02-25 | 2014-08-27 | 杭州赛利药物研究所有限公司 | 泮托拉唑钠冻干制剂及其制备方法 |
| CN104414979A (zh) * | 2013-08-21 | 2015-03-18 | 哈药集团三精制药股份有限公司 | 一种泮托拉唑钠冻干粉针剂及其制备方法 |
| CN104019635B (zh) * | 2014-06-19 | 2015-05-27 | 上海慈瑞医药科技有限公司 | 一种兰索拉唑原料药化合物及其干燥工艺 |
| CN104055792A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗中耳炎的用途 |
| CN104055791A (zh) * | 2014-07-10 | 2014-09-24 | 北京人福军威医药技术开发有限公司 | 西地碘治疗眼角结膜炎的用途 |
| BE1021311B1 (nl) * | 2014-07-31 | 2015-10-28 | Neogen N.V. | Werkwijze voor het maken van een poedervormige protonpompremmer samenstelling, genoemde samenstelling en gebruik |
| EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| CN111643460A (zh) * | 2020-06-30 | 2020-09-11 | 武汉九州钰民医药科技有限公司 | 泮托拉唑钠冻干制剂及其制备方法、由其制得的注射制剂 |
| US12102624B2 (en) | 2020-08-26 | 2024-10-01 | Nivagen Pharmaceuticals, Inc. | Pantoprazole compositions and methods |
| CN112274481A (zh) * | 2020-10-27 | 2021-01-29 | 海南卫康制药(潜山)有限公司 | 一种注射用泮托拉唑钠组合物及其制备方法 |
| JP2025524158A (ja) * | 2022-08-04 | 2025-07-25 | 江▲蘇▼柯菲平医▲薬▼股▲分▼有限公司 | ピロール類胃酸分泌抑制剤を含有する薬物組成物及びその調製方法 |
| WO2025041069A1 (en) | 2023-08-23 | 2025-02-27 | Reena Patel | Stabilized pharmaceutical compositions of proton pump inhibitors |
| WO2025181379A1 (en) | 2024-03-01 | 2025-09-04 | Etico Lifesciences Private Limited | Liquid, storage stable, directly injectable, pantoprazole formulations, their uses and manufacturing |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| IL75400A (en) | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| DK399389A (da) | 1988-08-18 | 1990-02-19 | Takeda Chemical Industries Ltd | Injicerbare oploesninger |
| US5223515A (en) | 1988-08-18 | 1993-06-29 | Takeda Chemical Industries, Ltd. | Injectable solution containing a pyridyl methylsulfinylbenzimidazole |
| DE4035455A1 (de) | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
| DK0652751T3 (da) | 1992-07-28 | 1996-11-18 | Astra Ab | Injektionspræparat og injektions-kit indeholdende omeprazol og dens analoger |
| WO1994024867A1 (en) | 1993-04-27 | 1994-11-10 | Sepracor, Inc. | Methods and compositions for treating gastric disorders using optically pure (-) pantoprazole |
| DE4324014C2 (de) * | 1993-07-17 | 1995-06-08 | Byk Gulden Lomberg Chem Fab | Verfahren zur Herstellung einer in Wasser rekonstituierbaren Zubereitung |
| TW280770B (es) | 1993-10-15 | 1996-07-11 | Takeda Pharm Industry Co Ltd | |
| FR2740686B1 (fr) | 1995-11-03 | 1998-01-16 | Sanofi Sa | Formulation pharmaceutique lyophilisee stable |
| HU224987B1 (en) | 1995-11-03 | 2006-05-29 | Sanofi Aventis | Stable freeze-dried pharmaceutical formulation |
| US5980882A (en) * | 1997-04-16 | 1999-11-09 | Medeva Pharmaceuticals Manufacturing | Drug-resin complexes stabilized by chelating agents |
| JP3459407B2 (ja) | 1997-10-14 | 2003-10-20 | エーザイ株式会社 | 安定剤としてグリシンを含む製薬学的製剤 |
| DE19843413C1 (de) * | 1998-08-18 | 2000-03-30 | Byk Gulden Lomberg Chem Fab | Neue Salzform von Pantoprazol |
| AU1907100A (en) | 1998-10-30 | 2000-05-22 | Curators Of The University Of Missouri, The | Omeprazole solution and method of using same |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| CN1235018A (zh) * | 1999-04-22 | 1999-11-17 | 沈阳东宇药业有限公司 | 泮托拉唑钠冻干粉针剂及制备方法 |
| SE9903831D0 (sv) * | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
| CA2419067C (en) * | 2000-08-18 | 2008-12-23 | Takeda Chemical Industries, Ltd. | Injectable composition comprising benzimidazole compound and strong alkali |
| MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
| AR045258A1 (es) | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
-
2001
- 2001-10-19 MY MYPI20014865A patent/MY137726A/en unknown
- 2001-11-06 TW TW090127545A patent/TWI284041B/zh not_active IP Right Cessation
- 2001-11-17 HR HR20030410A patent/HRP20030410B1/xx not_active IP Right Cessation
- 2001-11-17 KR KR1020077027736A patent/KR100910607B1/ko not_active Expired - Lifetime
- 2001-11-17 ES ES01997314T patent/ES2298295T3/es not_active Expired - Lifetime
- 2001-11-17 EP EP01997314A patent/EP1339430B1/en not_active Revoked
- 2001-11-17 DE DE60132108T patent/DE60132108T2/de not_active Expired - Lifetime
- 2001-11-17 AU AU2002216042A patent/AU2002216042B2/en not_active Expired
- 2001-11-17 RS YU37703A patent/RS52024B/sr unknown
- 2001-11-17 DK DK01997314T patent/DK1339430T3/da active
- 2001-11-17 KR KR1020037006675A patent/KR100910606B1/ko not_active Expired - Lifetime
- 2001-11-17 CN CNB01819379XA patent/CN1250292C/zh not_active Expired - Lifetime
- 2001-11-17 EP EP06123558.6A patent/EP1762249A3/en not_active Ceased
- 2001-11-17 SI SI200130816T patent/SI1339430T1/sl unknown
- 2001-11-17 EE EEP200300182A patent/EE05236B1/xx not_active IP Right Cessation
- 2001-11-17 PL PL361118A patent/PL201188B1/pl unknown
- 2001-11-17 ME MEP-696/08A patent/ME00556A/xx unknown
- 2001-11-17 PT PT01997314T patent/PT1339430E/pt unknown
- 2001-11-17 EA EA200300501A patent/EA007602B1/ru not_active IP Right Cessation
- 2001-11-17 SK SK606-2003A patent/SK287993B6/sk not_active IP Right Cessation
- 2001-11-17 HU HU0303278A patent/HUP0303278A3/hu unknown
- 2001-11-17 CZ CZ2003-1416A patent/CZ304348B6/cs not_active IP Right Cessation
- 2001-11-17 JP JP2002544096A patent/JP4886158B2/ja not_active Expired - Fee Related
- 2001-11-17 GE GE5180A patent/GEP20053461B/en unknown
- 2001-11-17 NZ NZ525911A patent/NZ525911A/en not_active IP Right Cessation
- 2001-11-17 IL IL15560101A patent/IL155601A0/xx unknown
- 2001-11-17 AU AU1604202A patent/AU1604202A/xx active Pending
- 2001-11-17 CA CA002541946A patent/CA2541946A1/en not_active Abandoned
- 2001-11-17 UA UA20040705223A patent/UA80961C2/uk unknown
- 2001-11-17 AT AT01997314T patent/ATE381946T1/de active
- 2001-11-17 CA CA002428870A patent/CA2428870C/en not_active Expired - Lifetime
- 2001-11-17 MX MXPA03004548A patent/MXPA03004548A/es active IP Right Grant
- 2001-11-17 BR BRPI0115483A patent/BRPI0115483B8/pt not_active IP Right Cessation
- 2001-11-17 WO PCT/EP2001/013296 patent/WO2002041919A1/en not_active Ceased
- 2001-11-19 AR ARP010105391A patent/AR034277A1/es not_active Application Discontinuation
- 2001-11-19 PE PE2001001153A patent/PE20020582A1/es active IP Right Grant
-
2002
- 2002-07-15 US US10/195,062 patent/US6780881B2/en not_active Expired - Lifetime
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2003
- 2003-04-28 IL IL155601A patent/IL155601A/en active IP Right Grant
- 2003-05-09 ZA ZA200303593A patent/ZA200303593B/en unknown
- 2003-05-19 IS IS6820A patent/IS2971B/is unknown
- 2003-05-19 EC EC2003004613A patent/ECSP034613A/es unknown
- 2003-05-20 BG BG107828A patent/BG66329B1/bg unknown
- 2003-05-21 NO NO20032303A patent/NO332937B1/no not_active IP Right Cessation
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2004
- 2004-05-28 US US10/855,703 patent/US7351723B2/en not_active Expired - Lifetime
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2008
- 2008-01-22 US US12/010,124 patent/US8754108B2/en not_active Expired - Lifetime
- 2008-02-28 CY CY20081100226T patent/CY1107896T1/el unknown
-
2013
- 2013-08-21 AR ARP130102967A patent/AR092374A2/es not_active Application Discontinuation
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