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AR022600A1 - ACETATO DE TER-BUTIL (E) (6-{2-[4-(4-FLUOROFENIL)-6-ISOPROPIL-2-METIL (METILSULFONIL) AMINO] PIRIMIDIN-5-IL VINIL} (4R, 6S) -2,2-DIMETIL [1,3] DIOXAN -4- ILO), PROCESO PARA SU FABRICACIoN ,COMPUESTOS INVOLUCRADOS EN DICHO PROCESO Y PROCESO PARA LA FABRICACION DE UN COMPUESTO INHIBIDOR DE LA HMG COA - Google Patents

ACETATO DE TER-BUTIL (E) (6-{2-[4-(4-FLUOROFENIL)-6-ISOPROPIL-2-METIL (METILSULFONIL) AMINO] PIRIMIDIN-5-IL VINIL} (4R, 6S) -2,2-DIMETIL [1,3] DIOXAN -4- ILO), PROCESO PARA SU FABRICACIoN ,COMPUESTOS INVOLUCRADOS EN DICHO PROCESO Y PROCESO PARA LA FABRICACION DE UN COMPUESTO INHIBIDOR DE LA HMG COA

Info

Publication number
AR022600A1
AR022600A1 ARP000100642A ARP000100642A AR022600A1 AR 022600 A1 AR022600 A1 AR 022600A1 AR P000100642 A ARP000100642 A AR P000100642A AR P000100642 A ARP000100642 A AR P000100642A AR 022600 A1 AR022600 A1 AR 022600A1
Authority
AR
Argentina
Prior art keywords
dimetile
metilsulfonyl
vinil
isopropil
pirimidin
Prior art date
Application number
ARP000100642A
Other languages
English (en)
Inventor
Koike Haruo
Kabaki Mikio
Philip Taylor Nigel
Joseph Diorazio Louis
Original Assignee
Astrazeneca Uk Ltd
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10847843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR022600(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Uk Ltd, Shionogi & Co filed Critical Astrazeneca Uk Ltd
Publication of AR022600A1 publication Critical patent/AR022600A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP000100642A 1999-02-17 2000-02-15 ACETATO DE TER-BUTIL (E) (6-{2-[4-(4-FLUOROFENIL)-6-ISOPROPIL-2-METIL (METILSULFONIL) AMINO] PIRIMIDIN-5-IL VINIL} (4R, 6S) -2,2-DIMETIL [1,3] DIOXAN -4- ILO), PROCESO PARA SU FABRICACIoN ,COMPUESTOS INVOLUCRADOS EN DICHO PROCESO Y PROCESO PARA LA FABRICACION DE UN COMPUESTO INHIBIDOR DE LA HMG COA AR022600A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9903472.0A GB9903472D0 (en) 1999-02-17 1999-02-17 Chemical process

Publications (1)

Publication Number Publication Date
AR022600A1 true AR022600A1 (es) 2002-09-04

Family

ID=10847843

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000100642A AR022600A1 (es) 1999-02-17 2000-02-15 ACETATO DE TER-BUTIL (E) (6-{2-[4-(4-FLUOROFENIL)-6-ISOPROPIL-2-METIL (METILSULFONIL) AMINO] PIRIMIDIN-5-IL VINIL} (4R, 6S) -2,2-DIMETIL [1,3] DIOXAN -4- ILO), PROCESO PARA SU FABRICACIoN ,COMPUESTOS INVOLUCRADOS EN DICHO PROCESO Y PROCESO PARA LA FABRICACION DE UN COMPUESTO INHIBIDOR DE LA HMG COA

Country Status (34)

Country Link
US (2) US6844437B1 (es)
EP (1) EP1155015B1 (es)
JP (3) JP2003518474A (es)
KR (1) KR100648160B1 (es)
CN (1) CN1145625C (es)
AR (1) AR022600A1 (es)
AT (1) ATE415398T1 (es)
AU (1) AU760145B2 (es)
BR (1) BRPI0008301B8 (es)
CA (1) CA2362594C (es)
CL (1) CL2003002336A1 (es)
CY (1) CY1108733T1 (es)
CZ (1) CZ299844B6 (es)
DE (1) DE60040905D1 (es)
DK (1) DK1155015T3 (es)
EE (2) EE05150B1 (es)
ES (1) ES2316349T3 (es)
GB (1) GB9903472D0 (es)
HK (1) HK1041265B (es)
HU (1) HU229835B1 (es)
IL (2) IL144793A0 (es)
IS (1) IS2709B3 (es)
MX (1) MXPA01008235A (es)
NO (1) NO320739B1 (es)
NZ (1) NZ513261A (es)
PL (1) PL218518B1 (es)
PT (1) PT1155015E (es)
RU (1) RU2243969C2 (es)
SI (1) SI1155015T1 (es)
SK (1) SK286988B6 (es)
TR (2) TR200102360T2 (es)
TW (1) TWI285202B (es)
WO (1) WO2000049014A1 (es)
ZA (1) ZA200106370B (es)

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CN103936680B (zh) * 2014-04-18 2016-08-24 润泽制药(苏州)有限公司 瑞舒伐他汀钙已知杂质的制备方法
CN104788387A (zh) * 2015-04-17 2015-07-22 浙江海森药业有限公司 高纯度瑞舒伐他汀钙的制备方法
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