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NO20083753L - Nye pyridinylaminoalkylen- og pyridinyloksyalkylen-syklopropanaminer, fremgangsmate for fremstilling derav og farmasoytiske sammensetninger inneholdende dem - Google Patents

Nye pyridinylaminoalkylen- og pyridinyloksyalkylen-syklopropanaminer, fremgangsmate for fremstilling derav og farmasoytiske sammensetninger inneholdende dem

Info

Publication number
NO20083753L
NO20083753L NO20083753A NO20083753A NO20083753L NO 20083753 L NO20083753 L NO 20083753L NO 20083753 A NO20083753 A NO 20083753A NO 20083753 A NO20083753 A NO 20083753A NO 20083753 L NO20083753 L NO 20083753L
Authority
NO
Norway
Prior art keywords
atom
pyridinyloxyalkylene
pyridinylaminoalkylene
cyclopropanamines
novel
Prior art date
Application number
NO20083753A
Other languages
English (en)
Norwegian (no)
Inventor
Brian Lockhart
Pierre Lestage
Solo Goldstein
Claude Guillonneau
Yves Charton
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO20083753L publication Critical patent/NO20083753L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20083753A 2006-01-30 2008-09-01 Nye pyridinylaminoalkylen- og pyridinyloksyalkylen-syklopropanaminer, fremgangsmate for fremstilling derav og farmasoytiske sammensetninger inneholdende dem NO20083753L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0600784A FR2896800B1 (fr) 2006-01-30 2006-01-30 Nouveaux composes pyridinylaminoalkylene-et pyridinyloxyalkylene-cyclopropanamines polysubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR2007/000170 WO2007085750A1 (fr) 2006-01-30 2007-01-30 Nouveaux composes pyridinylaminoalkylene- et pyridinyloxyalkylene- cyclopropanamines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
NO20083753L true NO20083753L (no) 2008-10-10

Family

ID=37102591

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083753A NO20083753L (no) 2006-01-30 2008-09-01 Nye pyridinylaminoalkylen- og pyridinyloksyalkylen-syklopropanaminer, fremgangsmate for fremstilling derav og farmasoytiske sammensetninger inneholdende dem

Country Status (28)

Country Link
US (1) US20100317698A1 (de)
EP (1) EP1979321B9 (de)
JP (1) JP2009525311A (de)
KR (1) KR101050910B1 (de)
CN (1) CN101374814B (de)
AR (1) AR059221A1 (de)
AT (1) ATE437857T1 (de)
AU (1) AU2007209235B2 (de)
BR (1) BRPI0710443A2 (de)
CA (1) CA2640482C (de)
CY (1) CY1109477T1 (de)
DE (1) DE602007001779D1 (de)
DK (1) DK1979321T3 (de)
EA (1) EA015227B1 (de)
ES (1) ES2330899T3 (de)
FR (1) FR2896800B1 (de)
GE (1) GEP20105090B (de)
HR (1) HRP20090523T1 (de)
MA (1) MA30222B1 (de)
MY (1) MY149068A (de)
NO (1) NO20083753L (de)
PL (1) PL1979321T3 (de)
PT (1) PT1979321E (de)
RS (1) RS51065B (de)
SI (1) SI1979321T1 (de)
UA (1) UA88116C2 (de)
WO (1) WO2007085750A1 (de)
ZA (1) ZA200806399B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2738806A1 (en) * 2008-10-14 2010-04-22 Psychogenics, Inc. Nicotinic acetylcholine receptor ligands and the uses thereof
EP2714041B1 (de) 2011-05-24 2016-10-19 Merck Sharp & Dohme Corp. Aryloxymethyl-cyclopropanderivate als pde10-hemmer
BR112017004334A2 (pt) * 2014-09-05 2018-08-07 Celgene Quanticel Res Inc inibidores de desmetilase específica de lisina-1.
US20180311238A1 (en) * 2017-04-28 2018-11-01 Saniona A/S Selective Agonist Of a6 Containing nAChRs
CN110483392A (zh) * 2018-05-14 2019-11-22 上海海和药物研究开发有限公司 合成n-保护的喹啉-7-基氧基甲基环丙基胺衍生物的方法及合成中间体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2376061A1 (en) * 1999-06-07 2000-12-14 Targacept, Inc. Pharmaceutical compositions and methods for use
JP2001261652A (ja) * 2000-03-21 2001-09-26 Suntory Ltd 二置換イミノヘテロサイクリック化合物
FR2810664B1 (fr) * 2000-06-27 2004-12-24 Adir Nouveaux composes cyclopropaniques 1,1 et 1,2-dissubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7098331B2 (en) * 2003-03-05 2006-08-29 Targacept, Inc. Arylvinylazacycloalkane compounds and methods of preparation and use thereof
FR2889188B1 (fr) * 2005-07-28 2007-09-07 Servier Lab Nouveaux composes 1,1-pyridinylaminocyclopropanamines polysubstitues, leur procede de preparation et les compositions phamaceutiques qui les contiennent
FR2889187B1 (fr) * 2005-07-28 2007-09-07 Servier Lab Nouveaux composes 1,1-pyridinyloxycyclopropanamines polysusbstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
KR101050910B1 (ko) 2011-07-20
PL1979321T3 (pl) 2009-10-30
CA2640482A1 (fr) 2007-08-02
EP1979321B9 (de) 2010-02-17
US20100317698A1 (en) 2010-12-16
KR20080090564A (ko) 2008-10-08
AU2007209235A1 (en) 2007-08-02
UA88116C2 (ru) 2009-09-10
ZA200806399B (en) 2009-11-25
DE602007001779D1 (de) 2009-09-10
FR2896800A1 (fr) 2007-08-03
ES2330899T3 (es) 2009-12-16
DK1979321T3 (da) 2009-11-02
MY149068A (en) 2013-07-15
GEP20105090B (en) 2010-10-11
WO2007085750A1 (fr) 2007-08-02
EP1979321A1 (de) 2008-10-15
CN101374814A (zh) 2009-02-25
BRPI0710443A2 (pt) 2011-08-16
AR059221A1 (es) 2008-03-19
JP2009525311A (ja) 2009-07-09
EA015227B1 (ru) 2011-06-30
PT1979321E (pt) 2009-08-31
CA2640482C (fr) 2011-04-19
MA30222B1 (fr) 2009-02-02
EP1979321B1 (de) 2009-07-29
FR2896800B1 (fr) 2008-04-11
CN101374814B (zh) 2011-05-25
ATE437857T1 (de) 2009-08-15
SI1979321T1 (sl) 2009-12-31
HK1126190A1 (en) 2009-08-28
HRP20090523T1 (hr) 2009-11-30
CY1109477T1 (el) 2014-08-13
EA200801681A1 (ru) 2009-02-27
RS51065B (sr) 2010-10-31
AU2007209235B2 (en) 2011-03-03

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