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NO20055688L - Organiske forbindelser - Google Patents

Organiske forbindelser

Info

Publication number
NO20055688L
NO20055688L NO20055688A NO20055688A NO20055688L NO 20055688 L NO20055688 L NO 20055688L NO 20055688 A NO20055688 A NO 20055688A NO 20055688 A NO20055688 A NO 20055688A NO 20055688 L NO20055688 L NO 20055688L
Authority
NO
Norway
Prior art keywords
compounds
organic compounds
muscarinic
meanings
receptor
Prior art date
Application number
NO20055688A
Other languages
English (en)
Other versions
NO20055688D0 (no
Inventor
Gurdip Bhalay
Stephen Paul Collingwood
Brian Cox
Urs Baettig
Nicholas James Devereux
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33420896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20055688(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0324887A external-priority patent/GB0324887D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20055688D0 publication Critical patent/NO20055688D0/no
Publication of NO20055688L publication Critical patent/NO20055688L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Forbindelser med formel I i salt eller zwitterionform hvori, R1, R2, R3, og R4 har betydningene som indikert i beskrivelsen, som er anvendelige for behandling av tilstander som medieres av muskarin M3 reseptor. Farmasøytiske sammensetninger som inneholder forbindelsene og en fremgangsmåte for fremstilling av forbindelsene er også beskrevet.
NO20055688A 2003-05-02 2005-12-01 Organiske forbindelser NO20055688L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0310232 2003-05-02
GB0324887A GB0324887D0 (en) 2003-10-24 2003-10-24 Organic compounds
PCT/EP2004/004605 WO2004096800A2 (en) 2003-05-02 2004-04-30 Quinuclidine derivatives binding to mucarinic m3 receptors

Publications (2)

Publication Number Publication Date
NO20055688D0 NO20055688D0 (no) 2005-12-01
NO20055688L true NO20055688L (no) 2006-01-09

Family

ID=33420896

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055688A NO20055688L (no) 2003-05-02 2005-12-01 Organiske forbindelser

Country Status (31)

Country Link
US (2) US20070060563A1 (no)
EP (1) EP1631569B1 (no)
JP (1) JP4416786B2 (no)
KR (1) KR100896544B1 (no)
AR (1) AR044134A1 (no)
AT (1) ATE440840T1 (no)
AU (1) AU2004234069B2 (no)
BR (1) BRPI0410238A (no)
CA (1) CA2523436C (no)
CL (1) CL2004000918A1 (no)
CO (1) CO5700782A2 (no)
CY (1) CY1109655T1 (no)
DE (1) DE602004022805D1 (no)
DK (1) DK1631569T3 (no)
EC (1) ECSP056134A (no)
ES (1) ES2331185T3 (no)
HR (1) HRP20050933A2 (no)
IL (1) IL171591A (no)
IS (1) IS2746B (no)
MA (1) MA27775A1 (no)
MX (1) MXPA05011739A (no)
MY (1) MY142652A (no)
NO (1) NO20055688L (no)
NZ (1) NZ542995A (no)
PE (1) PE20050465A1 (no)
PL (1) PL1631569T3 (no)
PT (1) PT1631569E (no)
RU (1) RU2363700C2 (no)
SI (1) SI1631569T1 (no)
TW (1) TWI340139B (no)
WO (1) WO2004096800A2 (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0428416D0 (en) * 2004-12-24 2005-02-02 Novartis Ag Organic compounds
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide
EP1894568A1 (en) * 2006-08-31 2008-03-05 Novartis AG Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
CA2672446A1 (en) * 2006-12-19 2008-06-26 Astrazeneca Ab Quinuclidinol derivatives as muscarinic receptor antagonists
EP1950196A1 (de) * 2007-01-29 2008-07-30 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Ammoniumhexafluorophosphaten
CN101796026B (zh) 2007-09-07 2013-10-23 施万制药 可用作毒蕈碱受体拮抗剂的含胍化合物
US8017617B2 (en) * 2007-12-14 2011-09-13 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
JP5584138B2 (ja) 2008-01-11 2014-09-03 ノバルティス アーゲー キナーゼ阻害剤としてのピリミジン類
EP2315589A4 (en) * 2008-05-13 2013-09-11 Astrazeneca Ab PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A beta2-ADRENOCEPTOR AGONIST
GB0808709D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New combination 295
WO2009138707A1 (en) * 2008-05-13 2009-11-19 Astrazeneca Ab Quinuclidine derivatives as muscarinic m3 receptor antagonists
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
WO2009153536A1 (en) * 2008-06-17 2009-12-23 Argenta Discovery Limited 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
KR20130087405A (ko) * 2010-06-22 2013-08-06 키에시 파르마슈티시 엣스. 피. 에이. 알칼로이드 아미노에스테르 유도체 및 이의 의약 조성물
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
AU2012220572A1 (en) 2011-02-25 2013-08-29 Irm Llc Compounds and compositions as trk inhibitors
JP2011195593A (ja) * 2011-06-30 2011-10-06 Astrazeneca Ab ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
RU2628082C2 (ru) * 2011-12-30 2017-08-14 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Хинуклидиновые эфиры 1-азагетероциклилуксусной кислоты в качестве антимускариновых средств, способ их получения и их лекарственные композиции
CN104470515B (zh) 2012-05-03 2016-12-07 圣路易斯药学院 用于增加神经营养肽的组合物和方法
TWI647227B (zh) * 2013-02-28 2019-01-11 日商安斯泰來製藥股份有限公司 ２－醯胺噻唑衍生物或其鹽
CZ306791B6 (cs) 2013-10-29 2017-07-12 Zentiva, K.S. Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě
PT108370B (pt) * 2015-03-30 2018-10-25 Hovione Farm S A Processo de preparação de brometo de aclidínio
PL3111978T3 (pl) 2015-07-03 2022-01-24 Novartis Ag Inhalator przystosowany do odczytu informacji przechowywanych w środkach przechowywania danych pojemnika

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
DK534178A (da) * 1977-12-16 1979-06-17 Interx Research Corp Anticholinerge midler med sektrtionshaemmende virkning
IT1230881B (it) * 1989-06-20 1991-11-08 Angeli Inst Spa Derivati del r(-) 3-chinuclidinolo
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
AU2001271027B2 (en) * 2000-07-11 2005-07-07 Msd K.K. Ester derivatives
UA75626C2 (en) * 2000-12-28 2006-05-15 Almirall Prodesfarma Ag Quinuclidine derivatives and medicinal compositions containing the same
UA76571C2 (en) * 2001-12-20 2006-08-15 Derivatives of 1-alkyl-1-azoniabicyclo [2.2.2.]octanecarbamate and use thereof as antagonists of muscarin receptor
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide

Also Published As

Publication number Publication date
KR100896544B1 (ko) 2009-05-07
ECSP056134A (es) 2006-04-19
CL2004000918A1 (es) 2005-02-11
US20100041887A1 (en) 2010-02-18
KR20060015572A (ko) 2006-02-17
MA27775A1 (fr) 2006-02-01
ATE440840T1 (de) 2009-09-15
AR044134A1 (es) 2005-08-24
RU2363700C2 (ru) 2009-08-10
NO20055688D0 (no) 2005-12-01
DE602004022805D1 (de) 2009-10-08
HRP20050933A2 (en) 2006-12-31
ES2331185T3 (es) 2009-12-23
PE20050465A1 (es) 2005-07-18
JP4416786B2 (ja) 2010-02-17
JP2006525267A (ja) 2006-11-09
IS8158A (is) 2005-11-30
DK1631569T3 (da) 2009-11-23
TW200505920A (en) 2005-02-16
CY1109655T1 (el) 2014-08-13
WO2004096800A3 (en) 2005-01-06
WO2004096800A2 (en) 2004-11-11
RU2005137360A (ru) 2006-07-27
HK1087704A1 (en) 2006-10-20
AU2004234069A1 (en) 2004-11-11
BRPI0410238A (pt) 2006-05-16
PL1631569T3 (pl) 2010-02-26
CA2523436C (en) 2011-11-01
US8168654B2 (en) 2012-05-01
EP1631569B1 (en) 2009-08-26
US20070060563A1 (en) 2007-03-15
IS2746B (is) 2011-08-15
CO5700782A2 (es) 2006-11-30
NZ542995A (en) 2009-02-28
MY142652A (en) 2010-12-15
MXPA05011739A (es) 2006-01-26
PT1631569E (pt) 2009-11-26
CA2523436A1 (en) 2004-11-11
SI1631569T1 (sl) 2010-01-29
IL171591A (en) 2010-11-30
TWI340139B (en) 2011-04-11
EP1631569A2 (en) 2006-03-08
AU2004234069B2 (en) 2008-02-21

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Legal Events

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