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NO20044146L - Karbonylaminoderivater som nye inhibitorer av histon-deacetylase - Google Patents

Karbonylaminoderivater som nye inhibitorer av histon-deacetylase

Info

Publication number
NO20044146L
NO20044146L NO20044146A NO20044146A NO20044146L NO 20044146 L NO20044146 L NO 20044146L NO 20044146 A NO20044146 A NO 20044146A NO 20044146 A NO20044146 A NO 20044146A NO 20044146 L NO20044146 L NO 20044146L
Authority
NO
Norway
Prior art keywords
histone deacetylase
novel inhibitors
carbonylamino derivatives
carbonylamino
derivatives
Prior art date
Application number
NO20044146A
Other languages
English (en)
Inventor
Marc Gustaaf Celine Verdonck
Leo Jacobus Jozef Backx
Kristof Van Emelen
Sven Franciscus Anna Va Brandt
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20044146L publication Critical patent/NO20044146L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
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US6897220B2 (en) 2001-09-14 2005-05-24 Methylgene, Inc. Inhibitors of histone deacetylase
KR20040093692A (ko) 2002-03-13 2004-11-08 얀센 파마슈티카 엔.브이. 히스톤 디아세틸라제의 신규한 저해제로서의 피페라지닐-,피페리디닐- 및 모르폴리닐-유도체
CN100503599C (zh) 2002-03-13 2009-06-24 詹森药业有限公司 作为组蛋白脱乙酰酶的新颖抑制剂的羰基氨基衍生物
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US7767679B2 (en) 2002-03-13 2010-08-03 Janssen Pharmaceutica N.V. Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
TWI319387B (en) 2002-04-05 2010-01-11 Astrazeneca Ab Benzamide derivatives
US8163764B2 (en) * 2002-04-26 2012-04-24 Asan Laboratories Company (Cayman) Limited Skincare methods
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DK1485348T3 (da) 2008-09-29
CA2476067A1 (en) 2003-09-18
US8071615B2 (en) 2011-12-06
EA200401200A1 (ru) 2005-02-24
US20090042920A1 (en) 2009-02-12
CA2476067C (en) 2011-09-20
US7446109B2 (en) 2008-11-04
CN1642907A (zh) 2005-07-20
MXPA04008796A (es) 2004-11-26
NZ534831A (en) 2007-01-26
AU2003212336A1 (en) 2003-09-22
US20050148613A1 (en) 2005-07-07
ES2306858T3 (es) 2008-11-16
PL370982A1 (en) 2005-06-13
KR20040090981A (ko) 2004-10-27
CN100503599C (zh) 2009-06-24
JP2005519950A (ja) 2005-07-07
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AU2003212336B2 (en) 2008-12-18

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