NO20041178L - Fremgangsmate for fremstilling av 6-(4-klorfenyl)-2,2-dimetyl-7-fenyl-2,3-dihydro-1H-pyrrolizin-5-yl-eddiksyre - Google Patents

Fremgangsmate for fremstilling av 6-(4-klorfenyl)-2,2-dimetyl-7-fenyl-2,3-dihydro-1H-pyrrolizin-5-yl-eddiksyre

Info

Publication number: NO20041178L
Authority: NO; Norway
Prior art keywords: pyrrolizin; chlorophenyl; dihydro; dimethyl; phenyl
Prior art date: 2001-08-23

Application number

NO20041178A

Other languages

English (en)

Other versions

NO328299B1 (no

Inventor

Stefan Laufer

Gerd Dannhardt

Thomas Kammermeier

Philipp Merckle

Hans-Guenter Striegel

Original Assignee

Merckle Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-23

Filing date

2004-03-19

Publication date

2004-04-22

2004-03-19 Application filed by Merckle Gmbh filed Critical Merckle Gmbh

2004-04-22 Publication of NO20041178L publication Critical patent/NO20041178L/no

2010-01-25 Publication of NO328299B1 publication Critical patent/NO328299B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20041178A 2001-08-23 2004-03-19 Fremgangsmate for fremstilling av 6-(4-klorfenyl)-2,2-dimetyl-7-fenyl-2,3-dihydro-1H-pyrrolizin-5-yl-eddiksyre og mellomprodukter NO328299B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10141285A DE10141285A1 (de)	2001-08-23	2001-08-23	Verfahren zur Herstellung von 6-(4-Chlorphenyl)-2,2-dimethyl-7-phnyl-2,3-dihydro-1H-pyrrolizin-5-yl-essigsäure
PCT/EP2002/009356 WO2003018583A1 (de)	2001-08-23	2002-08-21	Verfahren zur herstellung von 6-(4-chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizin-5-yl-essigsäure

Publications (2)

Publication Number	Publication Date
NO20041178L true NO20041178L (no)	2004-04-22
NO328299B1 NO328299B1 (no)	2010-01-25

Family

ID=7696330

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20041178A NO328299B1 (no)	2001-08-23	2004-03-19	Fremgangsmate for fremstilling av 6-(4-klorfenyl)-2,2-dimetyl-7-fenyl-2,3-dihydro-1H-pyrrolizin-5-yl-eddiksyre og mellomprodukter

Country Status (31)

Country	Link
US (1)	US7078535B2 (no)
EP (1)	EP1419160B1 (no)
JP (1)	JP4195379B2 (no)
KR (1)	KR100687472B1 (no)
CN (1)	CN1266152C (no)
AR (1)	AR035117A1 (no)
AT (1)	ATE417047T1 (no)
AU (1)	AU2002331168C1 (no)
BR (1)	BR0212009A (no)
CA (1)	CA2458339C (no)
CO (1)	CO5560556A2 (no)
CU (1)	CU23345A3 (no)
CY (1)	CY1109089T1 (no)
DE (2)	DE10141285A1 (no)
DK (1)	DK1419160T3 (no)
EA (1)	EA006436B1 (no)
ES (1)	ES2319268T3 (no)
GE (1)	GEP20063918B (no)
HR (1)	HRP20040263B1 (no)
HU (1)	HU228125B1 (no)
IL (2)	IL160047A0 (no)
MX (1)	MXPA04001664A (no)
NO (1)	NO328299B1 (no)
NZ (1)	NZ531113A (no)
PL (1)	PL367796A1 (no)
PT (1)	PT1419160E (no)
RS (1)	RS51877B (no)
TW (1)	TWI274755B (no)
UA (1)	UA75702C2 (no)
WO (1)	WO2003018583A1 (no)
ZA (1)	ZA200402209B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102005012971A1 (de) *	2005-03-21	2006-09-28	Merckle Gmbh	Polymorphe Form von 6-(4-Chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-essigsäure
WO2007108006A1 (en) *	2006-03-23	2007-09-27	Unichem Laboratories Limited	Process for the preparation of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2, 3-dihydro-1h-pyrrolizin-5-yl acetic acid and its intermediates
CZ2007752A3 (cs) *	2007-10-30	2009-05-13	Zentiva, A. S.	Nový zpusob výroby 2-(6-(4-chlorfenyl)-2,2-dimethyl-7-fenyl-2,3-dihydro-1H-pyrrolizin-5-yl)octové kyseliny (licofelonu)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0172371A1 (de)	1984-07-27	1986-02-26	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Verfahren zur Herstellung von Dehydroxypantolacton
DE3915450A1 (de)	1989-05-11	1990-11-15	Gerd Prof Dr Dannhardt	Substituierte pyrrolverbindungen und deren anwendung in der pharmazie
DE4419247A1 (de)	1994-06-01	1995-12-07	Merckle Gmbh	Sulfonylierte Pyrrolizincarbonsäureamide und deren Anwendung in der Pharmazie
DE4419246A1 (de)	1994-06-01	1995-12-07	Merckle Gmbh	Heteroarylsubstituierte Pyrrolizinverbindungen und deren Anwendung in der Pharmazie
DE4419315A1 (de)	1994-06-01	1995-12-07	Merckle Gmbh	Heteropyrrolizinverbindungen und deren Anwendung in der Pharmazie
CN1160357C (zh) *	2000-01-28	2004-08-04	默克勒有限公司	制备6-(4-氯苯基)-2,2-二甲基-7-苯基-2,3-二氢-1h-吡咯嗪-5-基乙酸的方法

2001
- 2001-08-23 DE DE10141285A patent/DE10141285A1/de not_active Withdrawn
2002
- 2002-08-13 AR ARP020103045A patent/AR035117A1/es active IP Right Grant
- 2002-08-21 MX MXPA04001664A patent/MXPA04001664A/es active IP Right Grant
- 2002-08-21 NZ NZ531113A patent/NZ531113A/en not_active IP Right Cessation
- 2002-08-21 US US10/486,911 patent/US7078535B2/en not_active Expired - Fee Related
- 2002-08-21 EA EA200400344A patent/EA006436B1/ru not_active IP Right Cessation
- 2002-08-21 AU AU2002331168A patent/AU2002331168C1/en not_active Ceased
- 2002-08-21 KR KR1020047002654A patent/KR100687472B1/ko not_active Expired - Fee Related
- 2002-08-21 CN CNB028164490A patent/CN1266152C/zh not_active Expired - Fee Related
- 2002-08-21 DE DE50213105T patent/DE50213105D1/de not_active Expired - Lifetime
- 2002-08-21 HR HRP20040263AA patent/HRP20040263B1/xx not_active IP Right Cessation
- 2002-08-21 BR BR0212009-7A patent/BR0212009A/pt not_active Application Discontinuation
- 2002-08-21 HU HU0401440A patent/HU228125B1/hu not_active IP Right Cessation
- 2002-08-21 JP JP2003523244A patent/JP4195379B2/ja not_active Expired - Fee Related
- 2002-08-21 UA UA2004032036A patent/UA75702C2/uk unknown
- 2002-08-21 IL IL16004702A patent/IL160047A0/xx unknown
- 2002-08-21 GE GE5474A patent/GEP20063918B/en unknown
- 2002-08-21 ES ES02767415T patent/ES2319268T3/es not_active Expired - Lifetime
- 2002-08-21 RS YU14604A patent/RS51877B/sr unknown
- 2002-08-21 PL PL02367796A patent/PL367796A1/xx unknown
- 2002-08-21 EP EP02767415A patent/EP1419160B1/de not_active Expired - Lifetime
- 2002-08-21 DK DK02767415T patent/DK1419160T3/da active
- 2002-08-21 CA CA002458339A patent/CA2458339C/en not_active Expired - Fee Related
- 2002-08-21 PT PT02767415T patent/PT1419160E/pt unknown
- 2002-08-21 WO PCT/EP2002/009356 patent/WO2003018583A1/de not_active Ceased
- 2002-08-21 AT AT02767415T patent/ATE417047T1/de active
- 2002-08-23 TW TW091119151A patent/TWI274755B/zh not_active IP Right Cessation
2004
- 2004-01-26 IL IL160047A patent/IL160047A/en not_active IP Right Cessation
- 2004-01-29 CU CU20040019A patent/CU23345A3/es not_active IP Right Cessation
- 2004-02-19 CO CO04014456A patent/CO5560556A2/es not_active Application Discontinuation
- 2004-03-19 ZA ZA200402209A patent/ZA200402209B/en unknown
- 2004-03-19 NO NO20041178A patent/NO328299B1/no not_active IP Right Cessation
2009
- 2009-03-06 CY CY20091100258T patent/CY1109089T1/el unknown

Also Published As

Publication number	Publication date
CY1109089T1 (el)	2014-07-02
PL367796A1 (en)	2005-03-07
IL160047A (en)	2010-11-30
CU23345A3 (es)	2009-02-20
JP4195379B2 (ja)	2008-12-10
ATE417047T1 (de)	2008-12-15
ZA200402209B (en)	2005-05-11
CO5560556A2 (es)	2005-09-30
CN1266152C (zh)	2006-07-26
NZ531113A (en)	2005-12-23
HUP0401440A3 (en)	2008-03-28
RS14604A (sr)	2007-02-05
HUP0401440A2 (hu)	2004-11-29
EP1419160A1 (de)	2004-05-19
GEP20063918B (en)	2006-09-11
US20040236117A1 (en)	2004-11-25
EA006436B1 (ru)	2005-12-29
CN1545516A (zh)	2004-11-10
KR20040029006A (ko)	2004-04-03
PT1419160E (pt)	2009-03-17
KR100687472B1 (ko)	2007-02-27
AR035117A1 (es)	2004-04-14
EA200400344A1 (ru)	2004-08-26
MXPA04001664A (es)	2004-05-31
ES2319268T3 (es)	2009-05-06
HU228125B1 (en)	2012-12-28
HRP20040263B1 (hr)	2012-07-31
JP2005501871A (ja)	2005-01-20
RS51877B (sr)	2012-02-29
NO328299B1 (no)	2010-01-25
DE50213105D1 (de)	2009-01-22
BR0212009A (pt)	2004-09-28
IL160047A0 (en)	2004-06-20
DE10141285A1 (de)	2003-03-27
AU2002331168B2 (en)	2007-11-15
AU2002331168C1 (en)	2008-06-05
US7078535B2 (en)	2006-07-18
UA75702C2 (en)	2006-05-15
WO2003018583A1 (de)	2003-03-06
CA2458339A1 (en)	2003-03-06
DK1419160T3 (da)	2009-04-14
EP1419160B1 (de)	2008-12-10
CA2458339C (en)	2009-07-21
TWI274755B (en)	2007-03-01
HRP20040263A2 (en)	2004-08-31
HK1060879A1 (en)	2004-08-27

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Legal Events

Date	Code	Title	Description
2014-03-24	MM1K	Lapsed by not paying the annual fees