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NO20044814L - Fremgangsmate for fremstilling av combretastaniner - Google Patents

Fremgangsmate for fremstilling av combretastaniner

Info

Publication number
NO20044814L
NO20044814L NO20044814A NO20044814A NO20044814L NO 20044814 L NO20044814 L NO 20044814L NO 20044814 A NO20044814 A NO 20044814A NO 20044814 A NO20044814 A NO 20044814A NO 20044814 L NO20044814 L NO 20044814L
Authority
NO
Norway
Prior art keywords
combretastanines
preparation
Prior art date
Application number
NO20044814A
Other languages
English (en)
Other versions
NO329701B1 (no
Inventor
Michel Lavigne
Jean-Paul Casimir
Stephane Mutti
Irina Malejonock
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20044814L publication Critical patent/NO20044814L/no
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of NO329701B1 publication Critical patent/NO329701B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C07C217/82Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
    • C07C217/84Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Catalysts (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Magnetic Ceramics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20044814A 2002-04-11 2004-11-05 Fremgangsmate for fremstilling av combretastaniner og mellomprodukt for fremgangsmaten NO329701B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0204499A FR2838437B1 (fr) 2002-04-11 2002-04-11 Procedes de preparation de combretastatines
PCT/FR2003/001117 WO2003084919A2 (fr) 2002-04-11 2003-04-09 Procedes de preparation de combretastatines

Publications (2)

Publication Number Publication Date
NO20044814L true NO20044814L (no) 2004-01-07
NO329701B1 NO329701B1 (no) 2010-12-06

Family

ID=28459732

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20044814A NO329701B1 (no) 2002-04-11 2004-11-05 Fremgangsmate for fremstilling av combretastaniner og mellomprodukt for fremgangsmaten
NO20101215A NO331372B1 (no) 2002-04-11 2010-09-01 Fremgangsmate for fremstilling av combretastatiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20101215A NO331372B1 (no) 2002-04-11 2010-09-01 Fremgangsmate for fremstilling av combretastatiner

Country Status (27)

Country Link
EP (3) EP1497255A2 (no)
JP (1) JP4299677B2 (no)
KR (1) KR101018983B1 (no)
CN (1) CN1291970C (no)
AR (2) AR039198A1 (no)
AU (1) AU2003260026B2 (no)
BR (1) BR0309087A (no)
CA (1) CA2481742C (no)
CR (1) CR7481A (no)
EA (1) EA007965B1 (no)
EC (1) ECSP045348A (no)
FR (1) FR2838437B1 (no)
HR (1) HRP20040935A2 (no)
IL (1) IL164247A0 (no)
MA (1) MA26407A1 (no)
ME (1) MEP91508A (no)
MX (1) MXPA04009112A (no)
NO (2) NO329701B1 (no)
NZ (1) NZ535318A (no)
OA (1) OA12804A (no)
PL (3) PL214129B1 (no)
RS (3) RS52331B (no)
TN (1) TNSN04201A1 (no)
TW (1) TWI262179B (no)
UA (1) UA76079C2 (no)
WO (1) WO2003084919A2 (no)
ZA (1) ZA200407417B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7235688B1 (en) 2004-11-04 2007-06-26 University Of Notre Dame Du Lac Process for preparing histone deacetylase inhibitors and intermediates thereof
FR2928148B1 (fr) * 2008-02-28 2013-01-18 Sanofi Aventis Procede de preparation de combretastatine
FR2939665B1 (fr) 2008-12-12 2011-10-07 Sanofi Aventis Combinaison antitumorale associant l'ave8062a et le docetaxel
FR2945210B1 (fr) 2009-05-07 2011-07-01 Sanofi Aventis Combinaison antitumorale comprenant l'ave8062 et le sorafenib
FR2953518B1 (fr) * 2009-12-03 2012-01-20 Sanofi Aventis Procede de preparation d'un derive de combretastatine
EP2481404A1 (en) 2010-11-15 2012-08-01 Sanofi An antitumoral combination comprising ombrabulin, a taxane derivative and a platinum derivative
EP2397135A1 (en) 2010-06-18 2011-12-21 Sanofi An antitumoral combination comprising ombrabulin, a taxane derivative and a platinum derivative
CN103140224A (zh) 2010-06-18 2013-06-05 赛诺菲 包含奥瑞布林、紫杉烷衍生物和铂衍生物的抗肿瘤组合
EP2407161A1 (en) 2010-07-13 2012-01-18 Sanofi An antitumoral combination comprising ombrabulin and bevacizumab
FR2968557A1 (fr) 2010-12-09 2012-06-15 Sanofi Aventis Combinaison antitumorale comprenant un derive de la famille des combretastatines et le cetuximab
FR2978662A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cisplatine, associee a la radiotherapie
FR2978663A1 (fr) 2011-08-01 2013-02-08 Sanofi Sa Combinaison antitumorale comprenant l'ombrabuline et le cetuximab, associee a la radiotherapie
CN103012248B (zh) * 2013-01-11 2014-11-05 浙江大德药业集团有限公司 氨基康普立停衍生物的合成及其作为口服抗肿瘤药物的应用
EP2805705B1 (en) 2013-05-23 2016-11-09 IP Gesellschaft für Management mbH Packaging with one or more administration units comprising a sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1 H-imidazol-4-yl)-propionic acid
EP4079327A1 (en) 2021-04-22 2022-10-26 Centaurus Polytherapeutics Payloads for drug-conjugates and their use for treating cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996237A (en) 1987-01-06 1991-02-26 Arizona Board Of Regents Combretastatin A-4
UA18265A (uk) * 1988-02-24 1997-12-25 Ф.Хоффманн-Ля Рош Аг Спосіб одержаhhя похідhих стильбеhу
NZ232897A (en) * 1989-04-03 1992-12-23 Squibb & Sons Inc Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogues, preparation and pharmaceutical compositions thereof
TW325458B (en) * 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
US5731353A (en) * 1993-09-08 1998-03-24 Ajinomoto Co., Inc. Stilbene derivatives and pharmaceutical compositions containing them
CN1053658C (zh) * 1994-04-06 2000-06-21 日本新药株式会社 氨基芪唑衍生物和药
TW334418B (en) * 1995-03-07 1998-06-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions
JP4551514B2 (ja) * 1999-07-23 2010-09-29 住友化学株式会社 不飽和炭化水素残基置換アニリン類の製造方法
GB9918912D0 (en) 1999-08-12 1999-10-13 Angiogene Pharm Ltd New stilbenes with vascular damaging activity

Also Published As

Publication number Publication date
TNSN04201A1 (fr) 2007-03-12
AU2003260026B2 (en) 2008-01-03
PL394820A1 (pl) 2011-09-12
AR039198A1 (es) 2005-02-09
RS52331B (sr) 2012-12-31
TWI262179B (en) 2006-09-21
NO20101215L (no) 2004-01-07
ZA200407417B (en) 2006-04-26
WO2003084919A2 (fr) 2003-10-16
CN1291970C (zh) 2006-12-27
RS20110561A2 (sr) 2012-10-31
PL213967B1 (pl) 2013-05-31
PL371629A1 (pl) 2005-06-27
EP2354118A1 (fr) 2011-08-10
AU2003260026A1 (en) 2003-10-20
BR0309087A (pt) 2005-02-09
FR2838437B1 (fr) 2004-06-04
EP2348012A1 (fr) 2011-07-27
PL394821A1 (pl) 2011-09-12
FR2838437A1 (fr) 2003-10-17
MA26407A1 (fr) 2004-12-01
WO2003084919A3 (fr) 2004-04-08
JP2005522478A (ja) 2005-07-28
EA007965B1 (ru) 2007-02-27
EP1497255A2 (fr) 2005-01-19
NO329701B1 (no) 2010-12-06
KR101018983B1 (ko) 2011-03-07
RS86504A (sr) 2007-02-05
NO331372B1 (no) 2011-12-12
AR082581A2 (es) 2012-12-19
OA12804A (fr) 2006-07-11
PL213708B1 (pl) 2013-04-30
RS20110562A3 (en) 2013-12-31
TW200401762A (en) 2004-02-01
UA76079C2 (en) 2006-06-15
HRP20040935A2 (en) 2005-10-31
JP4299677B2 (ja) 2009-07-22
RS20110561A3 (en) 2013-10-31
MXPA04009112A (es) 2004-12-07
PL214129B1 (pl) 2013-06-28
IL164247A0 (en) 2005-12-18
CA2481742C (fr) 2012-06-19
EA200401350A1 (ru) 2005-02-24
MEP91508A (bs) 2011-12-20
CA2481742A1 (fr) 2003-10-16
KR20040108717A (ko) 2004-12-24
ECSP045348A (es) 2004-11-26
RS20110562A2 (sr) 2012-10-31
NZ535318A (en) 2007-02-23
CR7481A (es) 2008-11-25
HK1075651A1 (en) 2005-12-23
CN1646476A (zh) 2005-07-27

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