[go: up one dir, main page]

NO20010331D0 - Ftalazinderivater som fosfodiesterase 4-inhibitorer - Google Patents

Ftalazinderivater som fosfodiesterase 4-inhibitorer

Info

Publication number
NO20010331D0
NO20010331D0 NO20010331A NO20010331A NO20010331D0 NO 20010331 D0 NO20010331 D0 NO 20010331D0 NO 20010331 A NO20010331 A NO 20010331A NO 20010331 A NO20010331 A NO 20010331A NO 20010331 D0 NO20010331 D0 NO 20010331D0
Authority
NO
Norway
Prior art keywords
phosphodiesterase
inhibitors
phthalazine derivatives
phthalazine
derivatives
Prior art date
Application number
NO20010331A
Other languages
English (en)
Other versions
NO20010331L (no
NO318988B1 (no
Inventor
Mauro Napoletano
Gabriele Norcini
Giancarlo Grancini
Franco Pellacini
Gian Marco Leali
Gabriele Morazzoni
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of NO20010331D0 publication Critical patent/NO20010331D0/no
Publication of NO20010331L publication Critical patent/NO20010331L/no
Publication of NO318988B1 publication Critical patent/NO318988B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/32Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/34Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20010331A 1998-07-21 2001-01-19 Ftalazinderivater som fosfodiesterase 4-inhibitorer NO318988B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT98MI001670A ITMI981670A1 (it) 1998-07-21 1998-07-21 Derivati ftalazinici inibitori della fosfodiesterasi 4
PCT/EP1999/004904 WO2000005218A1 (en) 1998-07-21 1999-07-13 Phthalazine derivatives phosphodiesterase 4 inhibitors

Publications (3)

Publication Number Publication Date
NO20010331D0 true NO20010331D0 (no) 2001-01-19
NO20010331L NO20010331L (no) 2001-03-20
NO318988B1 NO318988B1 (no) 2005-05-30

Family

ID=11380474

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20010331A NO318988B1 (no) 1998-07-21 2001-01-19 Ftalazinderivater som fosfodiesterase 4-inhibitorer

Country Status (35)

Country Link
US (2) US6329370B1 (no)
EP (2) EP1097142B1 (no)
JP (1) JP2002521370A (no)
KR (1) KR20010087161A (no)
CN (1) CN1127486C (no)
AP (1) AP2000001993A0 (no)
AR (1) AR019409A1 (no)
AT (1) ATE279397T1 (no)
AU (1) AU765457B2 (no)
BG (1) BG105063A (no)
BR (1) BR9911175A (no)
CA (1) CA2338044A1 (no)
CO (1) CO5090842A1 (no)
DE (1) DE69921139T2 (no)
EA (1) EA200100062A1 (no)
EE (1) EE200100039A (no)
HK (1) HK1039124B (no)
HR (1) HRP20010057A2 (no)
HU (1) HUP0102646A3 (no)
ID (1) ID28874A (no)
IL (1) IL139490A0 (no)
IS (1) IS5772A (no)
IT (1) ITMI981670A1 (no)
MX (1) MXPA01000670A (no)
NO (1) NO318988B1 (no)
NZ (1) NZ507926A (no)
OA (1) OA11582A (no)
PA (1) PA8478301A1 (no)
PE (1) PE20000755A1 (no)
PL (1) PL345187A1 (no)
SK (1) SK1002001A3 (no)
TW (1) TW509682B (no)
UA (1) UA68383C2 (no)
WO (1) WO2000005218A1 (no)
YU (1) YU77500A (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI981671A1 (it) 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodisterasi 4
DE19921567A1 (de) * 1999-05-11 2000-11-16 Basf Ag Verwendung von Phthalazine-Derivaten
DE19963607B4 (de) * 1999-12-23 2005-12-15 Schering Ag Verfahren zur Herstellung von 4-(Heteroaryl-methyl) halogen-1(2H)-phthalazinonen
ITMI20000261A1 (it) * 2000-02-16 2001-08-16 Zambon Group Processo per la preparazione di piridiniliden-ftalidi
US6703390B2 (en) * 2000-04-13 2004-03-09 Transgenomic, Inc. Sulfur containing dihydrophthalazine antagonists of excitatory amino acid receptors
US6525049B2 (en) * 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
AU2002220241A1 (en) * 2000-12-01 2002-06-11 Iconix Pharmaceuticals, Inc. Parb inhibitors
ITMI20022739A1 (it) * 2002-12-23 2004-06-24 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4.
ITMI20022738A1 (it) * 2002-12-23 2004-06-24 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4.
AU2004215624B2 (en) * 2003-02-25 2011-06-02 Topotarget Uk Limited Hydroxamic acid compounds comprising a bicyclic heteroaryl group as HDAC inhibitors
ITMI20031451A1 (it) * 2003-07-16 2005-01-17 Zambon Spa Derivati diidro-ftalazinici inibitori della fosfodiesterasi 4
CA2564996A1 (en) * 2004-05-08 2006-01-12 Taeyoung Yoon 3-aryl-5,6-disubstituted pyridazines
CA2593005A1 (en) * 2005-01-03 2006-07-13 Myriad Genetics Inc. Pharmaceutical compounds as activators of caspases and inducers of apoptosis and the use thereof
WO2007045979A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
WO2008061108A2 (en) 2006-11-15 2008-05-22 Forest Laboratories Holdings Limited Phthalazine derivatives
WO2010019417A2 (en) * 2008-08-13 2010-02-18 Boehringer Ingelheim International Gmbh Chymase inhibitors
CN102108078B (zh) * 2009-12-24 2013-10-30 沈阳药科大学 1,4-取代酞嗪类化合物及其制备方法和用途
HK1201523A1 (en) * 2011-11-09 2015-09-04 AbbVie Deutschland GmbH & Co. KG Heterocyclic carboxamides useful as inhibitors of phosphodiesterase type 10a
CN117924243B (zh) * 2024-01-16 2025-09-12 沈阳药科大学 一种喹啉衍生物及其药用组合物和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2063249A (en) * 1979-10-09 1981-06-03 Mitsubishi Yuka Pharma 4-Phenylphthalazine derivatives
JPH03106873A (ja) * 1989-09-20 1991-05-07 Morishita Pharmaceut Co Ltd 1―ピリジルフタラジン誘導体及びそれらを含有する血小板凝集抑制剤
EP0449203B1 (en) * 1990-03-30 1994-12-07 Mitsubishi Chemical Corporation 4-Phenylphthalazine derivatives
EP0634404A1 (en) * 1993-07-13 1995-01-18 Rhone Poulenc Agriculture Ltd. Phtalazin derivatives and their use as pesticides
HU219864B (hu) * 1994-08-09 2001-08-28 Eisai Co., Ltd. cGMP-PDE inhibitor kondenzált piridazinszármazékok és alkalmazásuk
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4

Also Published As

Publication number Publication date
ATE279397T1 (de) 2004-10-15
PA8478301A1 (es) 2000-09-29
ITMI981670A1 (it) 2000-01-21
PL345187A1 (en) 2001-12-03
JP2002521370A (ja) 2002-07-16
BR9911175A (pt) 2001-03-20
OA11582A (en) 2004-07-26
IL139490A0 (en) 2001-11-25
CN1305467A (zh) 2001-07-25
KR20010087161A (ko) 2001-09-15
DE69921139T2 (de) 2005-10-13
CO5090842A1 (es) 2001-10-30
YU77500A (sh) 2002-11-15
AR019409A1 (es) 2002-02-20
EP1097142A1 (en) 2001-05-09
ID28874A (id) 2001-07-12
TW509682B (en) 2002-11-11
MXPA01000670A (es) 2002-05-14
PE20000755A1 (es) 2000-09-01
DE69921139D1 (de) 2004-11-18
HUP0102646A2 (hu) 2001-12-28
US6329370B1 (en) 2001-12-11
EP1371648A1 (en) 2003-12-17
ITMI981670A0 (it) 1998-07-21
EE200100039A (et) 2002-06-17
EA200100062A1 (ru) 2001-08-27
HUP0102646A3 (en) 2003-01-28
NO20010331L (no) 2001-03-20
HK1039124B (zh) 2005-04-01
HK1039124A1 (en) 2002-04-12
NZ507926A (en) 2002-10-25
AP2000001993A0 (en) 2000-12-31
US6492360B1 (en) 2002-12-10
IS5772A (is) 2000-12-15
UA68383C2 (en) 2004-08-16
HRP20010057A2 (en) 2002-04-30
CN1127486C (zh) 2003-11-12
AU5281099A (en) 2000-02-14
AU765457B2 (en) 2003-09-18
NO318988B1 (no) 2005-05-30
SK1002001A3 (en) 2001-12-03
EP1097142B1 (en) 2004-10-13
WO2000005218A1 (en) 2000-02-03
BG105063A (en) 2001-07-31
CA2338044A1 (en) 2000-02-03

Similar Documents

Publication Publication Date Title
HUP0103349A3 (en) Phthalazine derivatives as phosphodiesterase 4 inhibitors
DK2253620T3 (da) Substituerede 3-cyanoquinoliner som protein-tyrosinkinase-inhibitorer
NO992725L (no) 6-Fenylpyridyl-2-amin-derivater anvendelige som NOS-inhibitorer
NO20010331L (no) Ftalazinderivater som fosfodiesterase 4-inhibitorer
DK1244647T3 (da) Quinzolinderivater som VIGF-inhibitorer
NO20010193L (no) Tiobenzimidazol-derivater
DK0930302T3 (da) Benzosulfonderivater
ATE256123T1 (de) Pyrimidonderivate
ATE435861T1 (de) 12,13-cyclopropan-epothilonderivate
IL141445A0 (en) Benzazine derivatives as phosphodiesterase 4 inhibitors
DK0927168T3 (da) 1,3-diheterocykliske metalloproteaseinhibitorer
DE69915704D1 (de) Ampic dram
NO20010514L (no) Aminometylkarboksylsyre-derivater
ATE259810T1 (de) Phenyl-xanthinderivate
NO20016201D0 (no) Tienopyrimidiner som fosfodiesteraseinhibitorer
IS5562A (is) Nýjar díhýdroxýhexanósýru afleiður
IL141446A0 (en) Benzazine derivatives as phosphodiesterase 4 inhibitors
EE200000447A (et) 1,3,4-oksadiasolooni derivaadid
DK1115716T3 (da) 2-phenylpyran-4-on-derivater
ATE252547T1 (de) Matrixmetalloproteinaseinhibitoren
DK1134219T3 (da) Cucloalkylsubstituerede aminomethylpyrrolidinderivater
ATE233253T1 (de) Chromanderivate
DK1060183T3 (da) 5-deoxycytidinderivater
DE69910409D1 (de) Disaccharide-derivate
DE59907635D1 (de) Pyrazolyldioxothiochromanoyl-derivate

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees