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MXPA03011784A - Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros. - Google Patents

Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros.

Info

Publication number
MXPA03011784A
MXPA03011784A MXPA03011784A MXPA03011784A MXPA03011784A MX PA03011784 A MXPA03011784 A MX PA03011784A MX PA03011784 A MXPA03011784 A MX PA03011784A MX PA03011784 A MXPA03011784 A MX PA03011784A MX PA03011784 A MXPA03011784 A MX PA03011784A
Authority
MX
Mexico
Prior art keywords
dispersions
pharmaceutical compositions
drugs
neutral polymers
acid
Prior art date
Application number
MXPA03011784A
Other languages
English (en)
Inventor
Jon Gumkowski Michael
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23158329&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA03011784(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MXPA03011784A publication Critical patent/MXPA03011784A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Es un aspecto, se exponen composiciones farmaceuticas que comprenden dispersiones de un farmaco sensible a acidos y un polimero de dispersion neutro; el farmaco sensible a acidos tiene una estabilidad quimica mejorada respecto de dispersiones del farmaco y polimeros acidos; en otro aspecto, se exponen composiciones farmaceuticas de farmacos de baja solubilidad y copolimeros vinilicos anfifilos con funciones hidroxilo.
MXPA03011784A 2001-06-22 2002-05-10 Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros. MXPA03011784A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30025501P 2001-06-22 2001-06-22
PCT/IB2002/001783 WO2003000235A1 (en) 2001-06-22 2002-05-10 Pharmaceutical compositions of dispersions of drugs and neutral polymers

Publications (1)

Publication Number Publication Date
MXPA03011784A true MXPA03011784A (es) 2004-04-02

Family

ID=23158329

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03011784A MXPA03011784A (es) 2001-06-22 2002-05-10 Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros.

Country Status (11)

Country Link
US (4) US20030091643A1 (es)
EP (1) EP1404300B1 (es)
JP (1) JP2004534812A (es)
AT (1) ATE444060T1 (es)
BR (1) BR0210518A (es)
CA (1) CA2450957A1 (es)
DE (1) DE60233874D1 (es)
ES (1) ES2333645T3 (es)
MX (1) MXPA03011784A (es)
PT (1) PT1404300E (es)
WO (1) WO2003000235A1 (es)

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US20060216351A1 (en) 2006-09-28
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EP1404300B1 (en) 2009-09-30
CA2450957A1 (en) 2003-01-03
WO2003000235A1 (en) 2003-01-03
EP1404300A1 (en) 2004-04-07
BR0210518A (pt) 2004-06-22
ES2333645T3 (es) 2010-02-25
US20140210117A1 (en) 2014-07-31
WO2003000235A9 (en) 2003-12-24
US20030091643A1 (en) 2003-05-15
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DE60233874D1 (de) 2009-11-12
US9468604B2 (en) 2016-10-18

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