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MX2023010042A - Polinucleotidos moduladores. - Google Patents

Polinucleotidos moduladores.

Info

Publication number
MX2023010042A
MX2023010042A MX2023010042A MX2023010042A MX2023010042A MX 2023010042 A MX2023010042 A MX 2023010042A MX 2023010042 A MX2023010042 A MX 2023010042A MX 2023010042 A MX2023010042 A MX 2023010042A MX 2023010042 A MX2023010042 A MX 2023010042A
Authority
MX
Mexico
Prior art keywords
modulatory polynucleotides
modulatory
polynucleotides
compositions
manufacture
Prior art date
Application number
MX2023010042A
Other languages
English (en)
Inventor
Dinah Wen-Yee Sah
Jinzhao Hou
Mathieu Nonnenmacher
Original Assignee
Voyager Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Voyager Therapeutics Inc filed Critical Voyager Therapeutics Inc
Publication of MX2023010042A publication Critical patent/MX2023010042A/es

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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/533—Physical structure partially self-complementary or closed having a mismatch or nick in at least one of the strands
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    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

La invención se refiere a composiciones y métodos para la preparación, fabricación y uso terapéutico de polinucleótidos moduladores.
MX2023010042A 2016-05-18 2018-11-16 Polinucleotidos moduladores. MX2023010042A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662338137P 2016-05-18 2016-05-18
US201762485050P 2017-04-13 2017-04-13

Publications (1)

Publication Number Publication Date
MX2023010042A true MX2023010042A (es) 2023-09-05

Family

ID=60325551

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018014154A MX2018014154A (es) 2016-05-18 2017-05-18 Polinucleotidos moduladores.
MX2023010042A MX2023010042A (es) 2016-05-18 2018-11-16 Polinucleotidos moduladores.

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Application Number Title Priority Date Filing Date
MX2018014154A MX2018014154A (es) 2016-05-18 2017-05-18 Polinucleotidos moduladores.

Country Status (13)

Country Link
US (3) US10584337B2 (es)
EP (1) EP3458588B1 (es)
JP (3) JP7066635B2 (es)
KR (3) KR102392236B1 (es)
CN (2) CN117904112A (es)
AU (2) AU2017267665C1 (es)
CA (2) CA3024448C (es)
IL (2) IL262784B2 (es)
MX (2) MX2018014154A (es)
RU (1) RU2758488C2 (es)
SG (1) SG11201809699XA (es)
WO (1) WO2017201248A1 (es)
ZA (1) ZA201807401B (es)

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