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MX2019013381A - Formas de dosificacion de liberacion prolongada para un inhibidor de jak 1 (cinasa de janus 1). - Google Patents

Formas de dosificacion de liberacion prolongada para un inhibidor de jak 1 (cinasa de janus 1).

Info

Publication number
MX2019013381A
MX2019013381A MX2019013381A MX2019013381A MX2019013381A MX 2019013381 A MX2019013381 A MX 2019013381A MX 2019013381 A MX2019013381 A MX 2019013381A MX 2019013381 A MX2019013381 A MX 2019013381A MX 2019013381 A MX2019013381 A MX 2019013381A
Authority
MX
Mexico
Prior art keywords
dosage forms
sustained release
release dosage
jak1 inhibitor
jak1
Prior art date
Application number
MX2019013381A
Other languages
English (en)
Other versions
MX394928B (es
Inventor
Parikh Bhavnish
Yeleswaram Krishnaswamy
P Modi Dilip
Sheth Trupti
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of MX2019013381A publication Critical patent/MX2019013381A/es
Publication of MX394928B publication Critical patent/MX394928B/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)

Abstract

La presente invención se refiere a formas de dosificación de liberación prolongada que comprenden {1-{1-[3-fluoro-2-(trifluorom etil)isonicotinoil]piperidin-4-il}-3-[4-(7H-pirrolo[2,3-d]pirimid in-4-il)-1H-pirazol-1-il]azetidin-3-il}acetonitrilo o una sal farmacéuticamente aceptable del mismo y dosis y métodos relacionadas con éstas.
MX2019013381A 2013-08-07 2014-08-06 Formas de dosificacion de liberacion prolongada para un inhibidor de jak 1 (cinasa de janus 1). MX394928B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361863325P 2013-08-07 2013-08-07
US201361913066P 2013-12-06 2013-12-06
PCT/US2014/049940 WO2015021153A1 (en) 2013-08-07 2014-08-06 Sustained release dosage forms for a jak1 inhibitor

Publications (2)

Publication Number Publication Date
MX2019013381A true MX2019013381A (es) 2020-02-20
MX394928B MX394928B (es) 2025-03-24

Family

ID=51383933

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019013381A MX394928B (es) 2013-08-07 2014-08-06 Formas de dosificacion de liberacion prolongada para un inhibidor de jak 1 (cinasa de janus 1).
MX2016001639A MX376856B (es) 2013-08-07 2014-08-06 Formas de dosificacion de liberacion prolongada para un inhibidor de jak 1 (cinasa de janus 1).

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2016001639A MX376856B (es) 2013-08-07 2014-08-06 Formas de dosificacion de liberacion prolongada para un inhibidor de jak 1 (cinasa de janus 1).

Country Status (31)

Country Link
US (5) US9655854B2 (es)
EP (2) EP3030227B1 (es)
JP (6) JP6334700B2 (es)
KR (3) KR102419714B1 (es)
CN (3) CN116036089A (es)
AU (3) AU2014305989B2 (es)
BR (1) BR122020001831A8 (es)
CA (2) CA2920108C (es)
CL (1) CL2016000292A1 (es)
CR (3) CR20230316A (es)
CY (1) CY1123314T1 (es)
DK (1) DK3030227T3 (es)
EA (1) EA201690357A1 (es)
ES (1) ES2792549T3 (es)
HR (1) HRP20200955T1 (es)
HU (1) HUE049345T2 (es)
IL (2) IL277554B2 (es)
LT (1) LT3030227T (es)
MX (2) MX394928B (es)
MY (2) MY195091A (es)
PE (2) PE20160223A1 (es)
PH (3) PH12019502074B1 (es)
PL (1) PL3030227T3 (es)
PT (1) PT3030227T (es)
RS (1) RS60469B1 (es)
SG (3) SG10201912203XA (es)
SI (1) SI3030227T1 (es)
SM (1) SMT202000315T1 (es)
TW (3) TWI822248B (es)
UA (1) UA120499C2 (es)
WO (1) WO2015021153A1 (es)

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