AU3565999A - Synthesis of azetidine derivatives - Google Patents
Synthesis of azetidine derivativesInfo
- Publication number
- AU3565999A AU3565999A AU35659/99A AU3565999A AU3565999A AU 3565999 A AU3565999 A AU 3565999A AU 35659/99 A AU35659/99 A AU 35659/99A AU 3565999 A AU3565999 A AU 3565999A AU 3565999 A AU3565999 A AU 3565999A
- Authority
- AU
- Australia
- Prior art keywords
- synthesis
- azetidine derivatives
- azetidine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001539 azetidines Chemical class 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1999/008361 WO2000063168A1 (en) | 1999-04-16 | 1999-04-16 | Synthesis of azetidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU3565999A true AU3565999A (en) | 2000-11-02 |
Family
ID=22272579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU35659/99A Abandoned AU3565999A (en) | 1999-04-16 | 1999-04-16 | Synthesis of azetidine derivatives |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU3565999A (en) |
| WO (1) | WO2000063168A1 (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2343298B9 (en) | 2005-12-13 | 2020-05-06 | Incyte Holdings Corporation | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors |
| RS53245B2 (en) | 2007-06-13 | 2022-10-31 | Incyte Holdings Corp | JANUS KINASE INHIBITOR SALTS (R)-3-(4-(7H-PYROLO(2,3-D) PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYLPROPANE-NITRILE |
| MY165582A (en) | 2008-03-11 | 2018-04-05 | Incyte Holdings Corp | Azetidine and cyclobutane derivatives as jak inhibitors |
| US8435977B2 (en) | 2009-04-22 | 2013-05-07 | Janssen Pharmaceutica, Nv | Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors |
| JP5649644B2 (en) | 2009-04-22 | 2015-01-07 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ | Azetidinyl diamide as a monoacylglycerol lipase inhibitor |
| WO2010135650A1 (en) | 2009-05-22 | 2010-11-25 | Incyte Corporation | N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS |
| HRP20192203T1 (en) | 2009-05-22 | 2020-03-06 | Incyte Holdings Corporation | 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors |
| TW201113285A (en) | 2009-09-01 | 2011-04-16 | Incyte Corp | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
| SI3354652T1 (en) | 2010-03-10 | 2020-08-31 | Incyte Holdings Corporation | Piperidin-4-yl azetidine derivatives as jak1 inhibitors |
| MY161078A (en) | 2010-05-21 | 2017-04-14 | Incyte Holdings Corp | Topical formulation for a jak inhibitor |
| BR112013005141A2 (en) | 2010-09-03 | 2016-05-10 | Janssen Pharmaceutica Nv | diazetidinyl diamide as monoacylglycerol lipase inhibitors |
| US8637498B2 (en) | 2010-09-27 | 2014-01-28 | Janssen Pharmaceutica, Nv | Oxopiperazine-azetidine amides and oxodiazepine-azetidine amides as monoacylglycerol lipase inhibitors |
| JP2013540160A (en) | 2010-10-22 | 2013-10-31 | ヤンセン ファーマシューティカ エヌ．ベー． | Amino-pyrrolidine-azetidine diamide as monoacylglycerol lipase inhibitor |
| US8513423B2 (en) | 2010-10-22 | 2013-08-20 | Janssen Pharmaceutica, Nv | Piperidin-4-yl-azetidine diamides as monoacylglycerol lipase inhibitors |
| WO2012068440A1 (en) | 2010-11-19 | 2012-05-24 | Incyte Corporation | Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors |
| JP5917545B2 (en) | 2010-11-19 | 2016-05-18 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors |
| PE20140832A1 (en) | 2011-06-20 | 2014-07-14 | Incyte Corp | DERIVATIVES OF AZETIDINYL PHENYL, PYRIDYL OR PYRAZINYL CARBOXAMIDE AS JAK INHIBITORS |
| TW201313721A (en) | 2011-08-18 | 2013-04-01 | Incyte Corp | Cyclohexyl azetidine derivatives as JAK inhibitors |
| UA111854C2 (en) | 2011-09-07 | 2016-06-24 | Інсайт Холдінгс Корпорейшн | METHODS AND INTERMEDIATE COMPOUNDS FOR JAK INHIBITORS |
| US9193733B2 (en) | 2012-05-18 | 2015-11-24 | Incyte Holdings Corporation | Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors |
| TWI702057B (en) | 2012-11-15 | 2020-08-21 | 美商英塞特控股公司 | Sustained-release dosage forms of ruxolitinib |
| ES2900492T3 (en) | 2013-03-06 | 2022-03-17 | Incyte Holdings Corp | Processes and intermediates to make a JAK inhibitor |
| RS60469B1 (en) | 2013-08-07 | 2020-07-31 | Incyte Corp | Sustained release dosage forms for a jak1 inhibitor |
| US9498467B2 (en) | 2014-05-30 | 2016-11-22 | Incyte Corporation | Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1 |
| AU2018238079B2 (en) | 2017-03-24 | 2022-03-03 | Wakunaga Pharmaceutical Co., Ltd. | Novel pyridone carboxylic acid derivative or salt thereof |
| TW201924683A (en) | 2017-12-08 | 2019-07-01 | 美商英塞特公司 | Low dose combination therapy for treatment of myeloproliferative neoplasms |
| PT3746429T (en) | 2018-01-30 | 2022-06-20 | Incyte Corp | Processes for preparing (1 -(3-fluoro-2-(trifluoromethyl)isonicotinyl)piperidine-4-one) |
| EP4424328A3 (en) | 2018-03-30 | 2024-12-04 | Incyte Corporation | Treatment of hidradenitis suppurativa using jak inhibitors |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5614663B2 (en) * | 1971-08-21 | 1981-04-06 | ||
| JPS49109369A (en) * | 1973-03-02 | 1974-10-17 | ||
| US4705853A (en) * | 1982-09-30 | 1987-11-10 | A. H. Robins Company, Inc. | Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof |
| FR2560194B1 (en) * | 1984-02-27 | 1987-08-07 | Midy Spa | 3-AMINOAZETIDINE, ITS SALTS, PROCESS FOR THEIR PREPARATION AND SYNTHESIS INTERMEDIATES |
| US4960776A (en) * | 1987-01-28 | 1990-10-02 | A. H. Robins Company, Inc. | 4-aryl-N-(alkylaminoalkyl, heterocyclicamino and heterocyclicamino)alkyl)-1-piperazinecarboxamides |
| FR2645862B1 (en) * | 1989-04-18 | 1991-07-12 | Esteve Labor Dr | SUBSTITUTED ISOTHIAZOLO-PYRYDONE AZETIDINYL DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS |
| FR2649100B1 (en) * | 1989-06-29 | 1994-03-04 | Laboratorios Dr Esteve Sa | NOVEL AZETIDINES, THEIR PREPARATION AND THEIR APPLICATION AS INTERMEDIATES FOR THE PREPARATION OF COMPOUNDS WITH ANTIMICROBIAL ACTIVITY |
| TW209870B (en) * | 1990-01-18 | 1993-07-21 | Pfizer | |
| US5442044A (en) * | 1991-01-04 | 1995-08-15 | Pfizer Inc. | Orally active renin inhibitors |
| FR2681865B1 (en) * | 1991-10-01 | 1993-11-19 | Bel Laboratoire Roger | NOVEL BENZONAPHTYRIDINE-1,8 DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM. |
| US5849780A (en) * | 1992-01-30 | 1998-12-15 | Sanofi | 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| ES2136291T3 (en) * | 1994-05-18 | 1999-11-16 | Nisshin Flour Milling Co | PIRIMIDINE DERIVATIVES. |
| TW432061B (en) * | 1994-08-09 | 2001-05-01 | Pfizer Res & Dev | Lactams |
| CA2294346A1 (en) * | 1997-06-18 | 1998-12-23 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
| AU1089599A (en) * | 1997-10-15 | 1999-05-03 | Coelacanth Chemical Corporation | Synthesis of azetidine derivatives |
-
1999
- 1999-04-16 WO PCT/US1999/008361 patent/WO2000063168A1/en not_active Ceased
- 1999-04-16 AU AU35659/99A patent/AU3565999A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000063168A1 (en) | 2000-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |