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MX2018002705A - Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. - Google Patents

Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.

Info

Publication number
MX2018002705A
MX2018002705A MX2018002705A MX2018002705A MX2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A
Authority
MX
Mexico
Prior art keywords
yeast strains
secretion
expression
high temperatures
heterologous proteins
Prior art date
Application number
MX2018002705A
Other languages
English (en)
Inventor
Argyros Aaron
F Rice Charles
Skinner Ryan
Barrett Trisha
Original Assignee
Lallemand Hungary Liquidity Man Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lallemand Hungary Liquidity Man Llc filed Critical Lallemand Hungary Liquidity Man Llc
Publication of MX2018002705A publication Critical patent/MX2018002705A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242—Fungal source
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente descripción se refiere a cepas de levadura recombinante capaces de mantener su resistencia a temperatura elevada así como proteínas recombinantes expresadas a partir de esta. La presente descripción también proporciona métodos para utilizar la cepa de levadura recombinante para elaborar un producto de fermentación. La presente descripción procesa además un proceso para elaborar cepas de levadura recombinante capaces de mantener su resistencia a temperatura elevada.
MX2018002705A 2015-09-04 2016-08-29 Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. MX2018002705A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562214412P 2015-09-04 2015-09-04
US201662299897P 2016-02-25 2016-02-25
PCT/IB2016/055162 WO2017037614A1 (en) 2015-09-04 2016-08-29 Yeast strains for the expression and secretion of heterologous proteins at high temperatures

Publications (1)

Publication Number Publication Date
MX2018002705A true MX2018002705A (es) 2018-12-19

Family

ID=56896745

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018002705A MX2018002705A (es) 2015-09-04 2016-08-29 Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.

Country Status (7)

Country Link
US (1) US11332728B2 (es)
EP (1) EP3344762A1 (es)
CN (1) CN108291213A (es)
BR (1) BR112018004377A2 (es)
CA (1) CA2997380A1 (es)
MX (1) MX2018002705A (es)
WO (1) WO2017037614A1 (es)

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US12442009B2 (en) 2016-12-22 2025-10-14 Danstar Ferment Ag Sulfite tolerance in recombinant yeast host cells
EP3596208A1 (en) * 2017-03-13 2020-01-22 Lallemand Hungary Liquidity Management LLC Recombinant yeast host cells expressing cell-associated heterologous proteins
BR122022015725B1 (pt) 2017-05-23 2023-03-14 Lallemand Hungary Liquidity Management Llc Processo para a produção de um produto de fermentação
MX2020009504A (es) * 2018-03-13 2021-01-15 Lallemand Hungary Liquidity Man Llc Levadura inactivada y producto de levadura para mejorar el rendimiento de fermentación.
US11866751B2 (en) 2018-07-25 2024-01-09 Novozymes A/S Yeast expressing a heterologous alpha-amylase for ethanol production
CA3114783A1 (en) 2018-10-08 2020-04-16 Novozymes A/S Enzyme-expressing yeast for ethanol production
BR112021008130A2 (pt) 2018-11-02 2021-08-03 Lallemand Hungary Liquidity Management Llc. processo para prevenir ou limitar contaminação microbiana durante cultura contínua
BR112021009163A2 (pt) 2018-11-13 2021-08-17 Lallemand Hungary Liquidity Management Llc. combinações sinergísticas de bactéria e levedura
BR112021009161A2 (pt) 2018-11-13 2021-08-31 Lallemand Hungary Liquidity Management Llc. Expressão combinada de enzimas de produção de trealose e degradação de trealose
US20220002661A1 (en) 2018-11-13 2022-01-06 Lallemand Hungary Liquidity Management Llc Modulation of formate oxidation by recombinant yeast host cell during fermentation
WO2020115716A1 (en) 2018-12-07 2020-06-11 Lallemand Hungary Liquidity Management Llc Modulation of nadph generation by recombinant yeast host cell during fermentation
BR112021026477A2 (pt) 2019-08-06 2022-02-08 Novozymes As Célula hospedeira recombinante, métodos de produção de um produto de fermentação a partir de um material contendo amido ou contendo celulose, de produção do polipeptídeo maduro, de produção de um derivado de uma célula hospedeira recombinante e de produção de etanol, construto de ácido nucleico ou vetor de expressão, composição, e, uso de uma célula hospedeira recombinante
WO2021104672A1 (en) 2019-11-29 2021-06-03 Lallemand Hungary Liquidity Management Llc Yeast expressing heterologous glucoamylase
BR112022010438A2 (pt) * 2019-11-29 2022-10-11 Lallemand Hungary Liquidity Man Llc Processo para deslocamento de uma enzima exógena
CA3158982A1 (en) 2019-12-10 2021-06-17 Monica TASSONE Microorganism for improved pentose fermentation
US20230235367A1 (en) 2020-02-10 2023-07-27 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
US20230142991A1 (en) 2020-02-10 2023-05-11 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CA3112751A1 (en) 2020-03-19 2021-09-19 Lallemand Hungary Liquidity Management Llc Bacterial cocultures expressing a bacteriocin system
CA3112754A1 (en) 2020-03-19 2021-09-19 Lallemand Hungary Liquidity Management Llc Yeast expressing glucoamylase with enhanced starch hydrolysis
BR112022022797A2 (pt) 2020-05-11 2022-12-13 Lallemand Hungary Liquidity Man Llc Célula hospedeira de levedura recombinante que expressa uma hidrolase
US12448631B2 (en) 2020-07-10 2025-10-21 Danstar Ferment Ag Bacterial-derived nitrogen source for ethanol fermentation
CN112831485B (zh) * 2021-01-13 2023-08-15 云南师范大学 一种低温活性改良的外切菊粉酶突变体MutDR121EH9
US20240084244A1 (en) 2021-01-26 2024-03-14 Danstar Ferment Ag Recombinant yeast host cell having enhanced growth rate
CN112662575B (zh) * 2021-01-28 2022-10-21 武汉轻工大学 高蛋白酶活性及高出酒率的扣囊复膜酵母菌、其组合物及应用
MX2023014545A (es) 2021-06-07 2024-03-01 Novozymes As Microorganismo diseñado para mejorar la fermentación del etanol.
BR102022012055A2 (pt) 2021-06-17 2023-01-10 Lallemand Hungary Liquidity Management Llc Cepas de levedura exibindo persistência prolongada durante uma pluralidade de ciclos de fermentação
CA3231720A1 (en) 2021-10-11 2023-04-20 Danstar Ferment Ag Recombinant yeast cell having increased pyruvate decarboxylase activity
EP4638768A2 (en) 2022-12-19 2025-10-29 Novozymes A/S Processes for producing fermentation products using fiber-degrading enzymes with engineered yeast
AU2024303961A1 (en) 2023-06-13 2025-12-11 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
WO2025133860A1 (en) 2023-12-21 2025-06-26 Danstar Ferment Ag Increased production of acetyl-phosphate and products derived therefrom in yeasts
CN118703501B (zh) * 2024-08-27 2025-03-21 安琪酵母（滨州）有限公司 启动子及其在构建产麦角甾醇的酵母菌株中的应用

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JP4460876B2 (ja) * 2003-11-07 2010-05-12 株式会社豊田中央研究所 有機酸存在下におけるプロモーター及びその利用
DK2069490T4 (en) * 2006-12-21 2018-04-23 Syngenta Participations Ag Amylases and Glucoamylases, Nucleic Acids Encoding Them, and Methods of Preparation and Use thereof
MX2010002931A (es) * 2007-09-18 2010-06-01 Basf Plant Science Gmbh Plantas con rendimiento incrementado.
US10676751B2 (en) * 2008-02-29 2020-06-09 The Trustees Of The University Of Pennsylvania Production and use of plant degrading materials
CN102112596B (zh) * 2008-05-06 2014-06-18 阿彻丹尼尔斯米德兰德公司 通过淀粉和木聚糖的降解酶的表达开发能进行淀粉和木聚糖的醇发酵的耐热酵母多形汉逊酵母菌株
BR112012018764A2 (pt) * 2009-12-30 2015-09-15 Iogen Energy Corp cepas de levedura modificadas exibindo co-fermentação melhorada de xilose e glicose em hidrolisados de lignocelulose
EP3168300A1 (en) * 2010-06-03 2017-05-17 Lallemand Hungary Liquidity Management LLC Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose
DK2694662T3 (da) 2011-04-05 2020-03-02 Lallemand Hungary Liquidity Man Llc Fremgangsmåder til forbedring af produktudbytte og fremstilling i en mikroorganisme gennem addition af alternerende elektronacceptorer
WO2013128648A1 (ja) 2012-03-02 2013-09-06 三菱電機株式会社 情報処理装置及び電子制御ユニット及び情報処理方法及びプログラム
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EP3253779A1 (en) 2015-02-06 2017-12-13 Cargill, Incorporated Modified glucoamylase enzymes and yeast strains having enhanced bioproduct production

Also Published As

Publication number Publication date
CA2997380A1 (en) 2017-03-09
CN108291213A (zh) 2018-07-17
US11332728B2 (en) 2022-05-17
BR112018004377A2 (pt) 2019-04-09
WO2017037614A1 (en) 2017-03-09
EP3344762A1 (en) 2018-07-11
US20180265853A1 (en) 2018-09-20

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