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MX2019013331A - Sistemas de produccion recombinante para policetidos prenilados de la familia de los cannabinoides. - Google Patents

Sistemas de produccion recombinante para policetidos prenilados de la familia de los cannabinoides.

Info

Publication number
MX2019013331A
MX2019013331A MX2019013331A MX2019013331A MX2019013331A MX 2019013331 A MX2019013331 A MX 2019013331A MX 2019013331 A MX2019013331 A MX 2019013331A MX 2019013331 A MX2019013331 A MX 2019013331A MX 2019013331 A MX2019013331 A MX 2019013331A
Authority
MX
Mexico
Prior art keywords
recombinant production
production systems
cannabinoid
cannabinoid family
prenylated polyketides
Prior art date
Application number
MX2019013331A
Other languages
English (en)
Inventor
Philip J Barr
Charles K Marlowe
Jianping Sun
Original Assignee
Baymedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baymedica Inc filed Critical Baymedica Inc
Publication of MX2019013331A publication Critical patent/MX2019013331A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y404/00—Carbon-sulfur lyases (4.4)
    • C12Y404/01—Carbon-sulfur lyases (4.4.1)
    • C12Y404/01026—Olivetolic acid cyclase (4.4.1.26)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se refiere generalmente a métodos de producción, enzimas y cepas de levadura recombinantes para la biosíntesis de policétidos prenilados clínicamente importantes de la familia de los cannabinoides. Utilizando materiales de inicio fácilmente disponibles, se utilizan enzimas heterólogas para dirigir la biosíntesis de cannabinoides en levadura.
MX2019013331A 2017-05-10 2018-05-10 Sistemas de produccion recombinante para policetidos prenilados de la familia de los cannabinoides. MX2019013331A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762504456P 2017-05-10 2017-05-10
PCT/US2018/032155 WO2018209143A1 (en) 2017-05-10 2018-05-10 Recombinant production systems for prenylated polyketides of the cannabinoid family

Publications (1)

Publication Number Publication Date
MX2019013331A true MX2019013331A (es) 2020-07-27

Family

ID=64105111

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019013331A MX2019013331A (es) 2017-05-10 2018-05-10 Sistemas de produccion recombinante para policetidos prenilados de la familia de los cannabinoides.

Country Status (7)

Country Link
US (2) US10837031B2 (es)
EP (1) EP3622059A4 (es)
CN (1) CN110869496A (es)
AU (2) AU2018265408B2 (es)
CA (1) CA3062645A1 (es)
MX (1) MX2019013331A (es)
WO (1) WO2018209143A1 (es)

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Also Published As

Publication number Publication date
CN110869496A (zh) 2020-03-06
EP3622059A1 (en) 2020-03-18
AU2018265408A1 (en) 2020-01-02
US11555211B2 (en) 2023-01-17
CA3062645A1 (en) 2018-11-15
WO2018209143A1 (en) 2018-11-15
EP3622059A4 (en) 2021-03-10
US20210040512A1 (en) 2021-02-11
AU2018265408B2 (en) 2024-12-12
AU2025201552A1 (en) 2025-03-20
US10837031B2 (en) 2020-11-17
US20180334692A1 (en) 2018-11-22

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