MX2013010340A - Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer. - Google Patents
Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer.Info
- Publication number
- MX2013010340A MX2013010340A MX2013010340A MX2013010340A MX2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- combination
- systemic
- effective amount
- therapeutically effective
- Prior art date
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract
Un método para el tratamiento del cáncer que comprende la administración de una cantidad terapéuticamente efectiva de una composición farmacéutica quimioablativa dentro de una lesión, o variante de la composición, en combinación con una cantidad terapéuticamente efectiva de un agente anticáncer inmunomodulador sistémico. Un método adicional para el tratamiento del cáncer que comprende la administración de una cantidad terapéuticamente efectiva de una composición farmacéutica quimioablativa dentro de una lesión, o variante de la composición, en combinación con una cantidad terapéuticamente efectiva de un agente anticáncer sistémico dirigido. La presente invención está dirigida además a una composición farmacéutica para el tratamiento del cáncer. La composición farmacéutica quimioablativa dentro de una lesión puede comprender un agente quimioablativo de IL que comprende principalmente un xanteno halogenado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161451395P | 2011-03-10 | 2011-03-10 | |
| PCT/US2012/028412 WO2012122444A1 (en) | 2011-03-10 | 2012-03-09 | Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013010340A true MX2013010340A (es) | 2013-11-01 |
| MX360254B MX360254B (es) | 2018-10-26 |
Family
ID=46798564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013010340A MX360254B (es) | 2011-03-10 | 2012-03-09 | Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer. |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US9107887B2 (es) |
| EP (1) | EP2710137B1 (es) |
| JP (2) | JP6322413B2 (es) |
| KR (1) | KR20140038382A (es) |
| CN (1) | CN103476943A (es) |
| CA (1) | CA2828940C (es) |
| ES (1) | ES2699965T3 (es) |
| MX (1) | MX360254B (es) |
| WO (1) | WO2012122444A1 (es) |
Families Citing this family (130)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1797881B1 (en) * | 2004-09-17 | 2009-04-15 | Eisai R&D Management Co., Ltd. | Medicinal composition with improved stability and reduced gelation properties |
| US9006240B2 (en) * | 2005-08-02 | 2015-04-14 | Eisai R&D Management Co., Ltd. | Method for assay on the effect of vascularization inhibitor |
| KR101353763B1 (ko) | 2005-11-07 | 2014-01-21 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 혈관 신생 저해 물질과 c―kit 키나아제 저해 물질의병용 |
| CA2652442C (en) * | 2006-05-18 | 2014-12-09 | Eisai R & D Management Co., Ltd. | Antitumor agent for thyroid cancer |
| US8962655B2 (en) * | 2007-01-29 | 2015-02-24 | Eisai R&D Management Co., Ltd. | Composition for treatment of undifferentiated gastric cancer |
| EP2218712B1 (en) * | 2007-11-09 | 2015-07-01 | Eisai R&D Management Co., Ltd. | Combination of anti-angiogenic substance and anti-tumor platinum complex |
| CA2771403C (en) | 2009-08-19 | 2015-02-24 | Eisai R&D Management Co. Ltd. | Quinoline derivative-containing pharmaceutical composition |
| BR112012032462A2 (pt) | 2010-06-25 | 2016-11-08 | Eisai R&D Man Co Ltd | agente antitumoral empregando compostos que, em combinação, têm efeito inibidor de quinase. |
| JP6322413B2 (ja) | 2011-03-10 | 2018-05-09 | プロヴェクタス ファーマテック,インク. | 改善されたがん治療のための局所および全身性免疫修飾療法の組み合わせ |
| MX2013009931A (es) * | 2011-04-18 | 2013-10-01 | Eisai R&D Man Co Ltd | Agentes terapeuticos contra tumores. |
| EP2714937B1 (en) | 2011-06-03 | 2018-11-14 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds |
| CN105457021A (zh) | 2012-05-04 | 2016-04-06 | 辉瑞公司 | 前列腺相关抗原及基于疫苗的免疫治疗疗法 |
| JP6457940B2 (ja) * | 2012-08-30 | 2019-01-23 | アムジエン・インコーポレーテツド | 単純ヘルペスウイルスおよび免疫チェックポイント阻害薬を使用して、メラノーマを治療するための方法 |
| RU2015115397A (ru) | 2012-12-21 | 2017-01-25 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Аморфная форма производного хинолина и способ его получения |
| TWI726291B (zh) * | 2013-01-07 | 2021-05-01 | 英屬維爾京群島商遠東超級實驗室有限公司 | 通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物 |
| KR20210084651A (ko) | 2013-04-18 | 2021-07-07 | 틸트 바이오세러퓨틱스 오이 | 향상된 입양 세포 치료 |
| US12421502B2 (en) | 2013-04-18 | 2025-09-23 | Tilt Biotherapeutics Oy | Enhanced adoptive cell therapy |
| CN105264380B (zh) | 2013-05-14 | 2017-09-05 | 卫材R&D管理有限公司 | 用于预测和评价子宫内膜癌受试者对乐伐替尼化合物响应性的生物标志 |
| AU2015218633A1 (en) * | 2014-02-21 | 2016-09-01 | Abbvie Stemcentrx Llc | Anti-DLL3 antibodies and drug conjugates for use in melanoma |
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| JP6322413B2 (ja) | 2011-03-10 | 2018-05-09 | プロヴェクタス ファーマテック,インク. | 改善されたがん治療のための局所および全身性免疫修飾療法の組み合わせ |
-
2012
- 2012-03-09 JP JP2013557888A patent/JP6322413B2/ja active Active
- 2012-03-09 CN CN2012800182901A patent/CN103476943A/zh active Pending
- 2012-03-09 US US13/416,494 patent/US9107887B2/en active Active
- 2012-03-09 ES ES12755115T patent/ES2699965T3/es active Active
- 2012-03-09 CA CA2828940A patent/CA2828940C/en active Active
- 2012-03-09 KR KR1020137026664A patent/KR20140038382A/ko not_active Ceased
- 2012-03-09 WO PCT/US2012/028412 patent/WO2012122444A1/en not_active Ceased
- 2012-03-09 MX MX2013010340A patent/MX360254B/es active IP Right Grant
- 2012-03-09 EP EP12755115.8A patent/EP2710137B1/en active Active
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2015
- 2015-06-24 US US14/748,579 patent/US20150290309A1/en not_active Abandoned
- 2015-06-24 US US14/748,634 patent/US9808524B2/en active Active
- 2015-06-24 US US14/748,608 patent/US9839688B2/en active Active
-
2017
- 2017-11-06 US US15/804,357 patent/US10471144B2/en active Active
-
2018
- 2018-02-19 JP JP2018026788A patent/JP2018109036A/ja active Pending
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2019
- 2019-11-08 US US16/678,133 patent/US11071781B2/en active Active
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2021
- 2021-07-22 US US17/382,943 patent/US20220008534A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN103476943A (zh) | 2013-12-25 |
| US20150290165A1 (en) | 2015-10-15 |
| EP2710137A1 (en) | 2014-03-26 |
| US9808524B2 (en) | 2017-11-07 |
| JP6322413B2 (ja) | 2018-05-09 |
| CA2828940C (en) | 2024-04-16 |
| US20180055926A1 (en) | 2018-03-01 |
| US20150290318A1 (en) | 2015-10-15 |
| JP2014510728A (ja) | 2014-05-01 |
| JP2018109036A (ja) | 2018-07-12 |
| US20200138942A1 (en) | 2020-05-07 |
| US20120263677A1 (en) | 2012-10-18 |
| MX360254B (es) | 2018-10-26 |
| CA2828940A1 (en) | 2012-09-13 |
| EP2710137B1 (en) | 2018-09-19 |
| US10471144B2 (en) | 2019-11-12 |
| US9839688B2 (en) | 2017-12-12 |
| EP2710137A4 (en) | 2014-12-31 |
| WO2012122444A1 (en) | 2012-09-13 |
| US11071781B2 (en) | 2021-07-27 |
| KR20140038382A (ko) | 2014-03-28 |
| US9107887B2 (en) | 2015-08-18 |
| US20150290309A1 (en) | 2015-10-15 |
| US20220008534A1 (en) | 2022-01-13 |
| ES2699965T3 (es) | 2019-02-13 |
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