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MX2010001319A - Metodo para producir proteinas heterogeneas. - Google Patents

Metodo para producir proteinas heterogeneas.

Info

Publication number
MX2010001319A
MX2010001319A MX2010001319A MX2010001319A MX2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A
Authority
MX
Mexico
Prior art keywords
heterogeneous protein
producing
producing heterogeneous
protein
polypeptide
Prior art date
Application number
MX2010001319A
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Tomoya Sugiyama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2010001319A publication Critical patent/MX2010001319A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01002—Alanine transaminase (2.6.1.2), i.e. alanine-aminotransferase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona un método capaz de producir una proteína natural o recombinante en rendimiento elevado. La presente invención se relaciona con un método para producir un polipéptido, que comprende cultivar una célula que expresa fuertemente aminotransferasa de alanina y tiene un ADN transferido que codifica un polipéptido deseado de esta manera permitir que la célula produzca el polipéptido.
MX2010001319A 2007-08-07 2008-08-06 Metodo para producir proteinas heterogeneas. MX2010001319A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007205158 2007-08-07
PCT/JP2008/064095 WO2009020144A1 (ja) 2007-08-07 2008-08-06 異種タンパク質の製造方法

Publications (1)

Publication Number Publication Date
MX2010001319A true MX2010001319A (es) 2010-06-01

Family

ID=40341376

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001319A MX2010001319A (es) 2007-08-07 2008-08-06 Metodo para producir proteinas heterogeneas.

Country Status (14)

Country Link
US (3) US8697397B2 (es)
EP (1) EP2186905B1 (es)
JP (1) JP5337033B2 (es)
KR (1) KR101577839B1 (es)
CN (1) CN101809161B (es)
AU (1) AU2008284753B2 (es)
BR (1) BRPI0815036B1 (es)
CA (1) CA2695849C (es)
DK (1) DK2186905T3 (es)
ES (1) ES2591284T3 (es)
MX (1) MX2010001319A (es)
RU (1) RU2487168C2 (es)
TW (1) TWI463013B (es)
WO (1) WO2009020144A1 (es)

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JP5337044B2 (ja) 2007-10-24 2013-11-06 中外製薬株式会社 異種タンパク質製造のための細胞及びそれを用いた製造方法
JP5715050B2 (ja) * 2009-04-22 2015-05-07 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法
MX374851B (es) 2010-05-28 2025-03-06 Genentech Inc Disminuir nivel de lactato e incrementar produccion de polipeptidos por regulacion a la baja de la expresion de lactato dehidrogenasa y piruvato dehidrogenasa quinasa
TWI647309B (zh) 2011-04-01 2019-01-11 Chugai Seiyaku Kabushiki Kaisha 重組多肽之製造方法
CN112522353A (zh) * 2012-10-10 2021-03-19 中外制药株式会社 经修饰的宿主细胞的建立方法
KR20210037745A (ko) 2013-03-15 2021-04-06 제넨테크, 인크. 항산화제를 함유하는 세포 배양 조성물 및 폴리펩티드 생산 방법
CA2934412C (en) 2013-12-20 2024-02-20 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
CA2934411C (en) 2013-12-20 2022-05-03 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
CN103923872B (zh) * 2014-04-17 2015-11-18 湖北工业大学 一种米曲霉活力强化剂及其培养方法
CN106233219B (zh) * 2015-03-31 2020-03-17 深圳市大疆创新科技有限公司 移动平台操作系统及方法
TWI797060B (zh) 2015-08-04 2023-04-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
WO2020122049A1 (ja) 2018-12-11 2020-06-18 富士フイルム株式会社 動物細胞、動物細胞の製造方法および目的タンパク質の製造方法
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
KR102479900B1 (ko) * 2020-12-11 2022-12-26 대한민국 내염성 증진 신품종 식물
CN118755734A (zh) * 2024-06-28 2024-10-11 中国水稻研究所 一种改良水稻产量和品质的方法

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Also Published As

Publication number Publication date
TWI463013B (zh) 2014-12-01
BRPI0815036B1 (pt) 2022-09-20
US20140309405A1 (en) 2014-10-16
AU2008284753A1 (en) 2009-02-12
CN101809161A (zh) 2010-08-18
US20100167346A1 (en) 2010-07-01
EP2186905A1 (en) 2010-05-19
KR101577839B1 (ko) 2015-12-15
CA2695849C (en) 2018-10-16
AU2008284753B2 (en) 2014-01-16
CA2695849A1 (en) 2009-02-12
US9284374B2 (en) 2016-03-15
RU2487168C2 (ru) 2013-07-10
EP2186905A4 (en) 2010-09-01
ES2591284T3 (es) 2016-11-25
WO2009020144A1 (ja) 2009-02-12
US20150315624A1 (en) 2015-11-05
JP5337033B2 (ja) 2013-11-06
EP2186905B1 (en) 2016-07-13
CN101809161B (zh) 2014-03-12
TW200920845A (en) 2009-05-16
RU2010108308A (ru) 2011-09-20
HK1143608A1 (zh) 2011-01-07
DK2186905T3 (en) 2016-09-19
US8697397B2 (en) 2014-04-15
KR20100057598A (ko) 2010-05-31
BRPI0815036A2 (pt) 2014-10-14
US9499618B2 (en) 2016-11-22
JPWO2009020144A1 (ja) 2010-11-04

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