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BRPI0815036A2 - Método de produção de proteína heterogêneas - Google Patents

Método de produção de proteína heterogêneas

Info

Publication number
BRPI0815036A2
BRPI0815036A2 BRPI0815036-2A2A BRPI0815036A BRPI0815036A2 BR PI0815036 A2 BRPI0815036 A2 BR PI0815036A2 BR PI0815036 A BRPI0815036 A BR PI0815036A BR PI0815036 A2 BRPI0815036 A2 BR PI0815036A2
Authority
BR
Brazil
Prior art keywords
production method
protein production
heterogeneous protein
heterogeneous
protein
Prior art date
Application number
BRPI0815036-2A2A
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Tomoya Sugiyama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0815036A2 publication Critical patent/BRPI0815036A2/pt
Publication of BRPI0815036B1 publication Critical patent/BRPI0815036B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1096Transferases (2.) transferring nitrogenous groups (2.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y206/00Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01Transaminases (2.6.1)
    • C12Y206/01002Alanine transaminase (2.6.1.2), i.e. alanine-aminotransferase
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
BRPI0815036-2A 2007-08-07 2008-08-06 Métodos para produção de um polipeptídeo e para preparação de um produto farmacêutico BRPI0815036B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007205158 2007-08-07
JP2007-205158 2007-08-07
PCT/JP2008/064095 WO2009020144A1 (ja) 2007-08-07 2008-08-06 異種タンパク質の製造方法

Publications (2)

Publication Number Publication Date
BRPI0815036A2 true BRPI0815036A2 (pt) 2014-10-14
BRPI0815036B1 BRPI0815036B1 (pt) 2022-09-20

Family

ID=40341376

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815036-2A BRPI0815036B1 (pt) 2007-08-07 2008-08-06 Métodos para produção de um polipeptídeo e para preparação de um produto farmacêutico

Country Status (14)

Country Link
US (3) US8697397B2 (pt)
EP (1) EP2186905B1 (pt)
JP (1) JP5337033B2 (pt)
KR (1) KR101577839B1 (pt)
CN (1) CN101809161B (pt)
AU (1) AU2008284753B2 (pt)
BR (1) BRPI0815036B1 (pt)
CA (1) CA2695849C (pt)
DK (1) DK2186905T3 (pt)
ES (1) ES2591284T3 (pt)
MX (1) MX2010001319A (pt)
RU (1) RU2487168C2 (pt)
TW (1) TWI463013B (pt)
WO (1) WO2009020144A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007119774A1 (ja) 2006-04-13 2007-10-25 Chugai Seiyaku Kabushiki Kaisha タウリントランスポーター遺伝子
US20100233759A1 (en) 2007-03-15 2010-09-16 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
EP2186905B1 (en) 2007-08-07 2016-07-13 Chugai Seiyaku Kabushiki Kaisha Method of producing heterogeneous protein
WO2009051109A1 (ja) * 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
JP5337044B2 (ja) 2007-10-24 2013-11-06 中外製薬株式会社 異種タンパク質製造のための細胞及びそれを用いた製造方法
JP5715050B2 (ja) * 2009-04-22 2015-05-07 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法
MX374851B (es) 2010-05-28 2025-03-06 Genentech Inc Disminuir nivel de lactato e incrementar produccion de polipeptidos por regulacion a la baja de la expresion de lactato dehidrogenasa y piruvato dehidrogenasa quinasa
TWI647309B (zh) 2011-04-01 2019-01-11 Chugai Seiyaku Kabushiki Kaisha 重組多肽之製造方法
CN112522353A (zh) * 2012-10-10 2021-03-19 中外制药株式会社 经修饰的宿主细胞的建立方法
KR20210037745A (ko) 2013-03-15 2021-04-06 제넨테크, 인크. 항산화제를 함유하는 세포 배양 조성물 및 폴리펩티드 생산 방법
CA2934412C (en) 2013-12-20 2024-02-20 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
CA2934411C (en) 2013-12-20 2022-05-03 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
CN103923872B (zh) * 2014-04-17 2015-11-18 湖北工业大学 一种米曲霉活力强化剂及其培养方法
CN106233219B (zh) * 2015-03-31 2020-03-17 深圳市大疆创新科技有限公司 移动平台操作系统及方法
TWI797060B (zh) 2015-08-04 2023-04-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
WO2020122049A1 (ja) 2018-12-11 2020-06-18 富士フイルム株式会社 動物細胞、動物細胞の製造方法および目的タンパク質の製造方法
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
KR102479900B1 (ko) * 2020-12-11 2022-12-26 대한민국 내염성 증진 신품종 식물
CN118755734A (zh) * 2024-06-28 2024-10-11 中国水稻研究所 一种改良水稻产量和品质的方法

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9019812D0 (en) 1990-09-11 1990-10-24 Scotgen Ltd Novel antibodies for treatment and prevention of infection in animals and man
GB9028123D0 (en) * 1990-12-28 1991-02-13 Erba Carlo Spa Monoclonal antibodies against human tumor necrosis factor alpha
US6225115B1 (en) * 1992-03-04 2001-05-01 Synaptic Pharmaceutical Corporation DNA encoding taurine and GABA transporters and uses thereof
US5658786A (en) * 1992-03-04 1997-08-19 Synaptic Pharmaceutical Corporation DNA encoding rat taurine transporter and uses thereof
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
JP3630453B2 (ja) 1994-09-30 2005-03-16 中外製薬株式会社 Il−6レセプター抗体を有効成分とする未熟型骨髄腫細胞治療剤
AU695117B2 (en) 1994-10-06 1998-08-06 Hoechst Aktiengesellschaft Regulated genes by stimulation of chondrocytes with IL-1beta
JPH09203734A (ja) 1996-01-26 1997-08-05 Sumitomo Electric Ind Ltd 抗血清、抗体、リガンド及びそれらの検出方法
JPH1075787A (ja) * 1996-09-02 1998-03-24 Asahi Chem Ind Co Ltd 変異型アラニンアミノトランスフェラーゼおよびその製造法
JPH10191984A (ja) * 1997-01-09 1998-07-28 Oriental Yeast Co Ltd 活性型ヒトaltの製造法
DE19855313A1 (de) 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen
JP2000236877A (ja) * 1999-02-23 2000-09-05 Internatl Reagents Corp 精度管理用物質
DE60034954D1 (de) * 1999-09-14 2007-07-05 Xenoport Inc Substrate und screeningverfahren für transportproteine
US6812339B1 (en) * 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
US20040234977A1 (en) * 2001-05-14 2004-11-25 Da-Wei Gong Novel alanine transaminase enzyme and methods of use
CN1292655C (zh) 2001-11-08 2007-01-03 蛋白质设计实验室股份有限公司 IgG抗体稳定的液态药物制剂
JP4532116B2 (ja) * 2002-01-18 2010-08-25 ノボザイムズ エー/エス アラニン2,3−アミノムターゼ
US20050265983A1 (en) * 2002-11-17 2005-12-01 Eldad Melamed Methods, nucleic acid constructs and cells for treating neurodegenerative disorders
IL152905A0 (en) 2002-11-17 2003-06-24 Univ Ramot Dopaminergic markers induction in neuronal-like cells isolated from adult human bone marrow stromal cells: implications for novel gene therapy strategy for parkinsons disease
US20030165495A1 (en) * 2003-04-01 2003-09-04 Carulli John P. Nucleic acids and polypeptides
US7147713B2 (en) 2003-04-30 2006-12-12 Cree, Inc. Phase controlled sublimation
DE60325906D1 (de) * 2003-08-08 2009-03-05 Amgen Fremont Inc Antikörper gegen parath-hormon (pth) und ihre verwendungen
WO2005076015A1 (en) 2004-01-30 2005-08-18 Xenoport, Inc. Taurine transporter tau1 expressed in blood brain barrier cells
KR100789645B1 (ko) * 2004-04-14 2007-12-27 주식회사유한양행 B형 간염바이러스의 s-표면항원을 인식하는 인간화 항체및 이의 제조방법
CA2544692C (en) * 2004-07-09 2014-04-01 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
RU2357758C2 (ru) 2004-10-07 2009-06-10 Кабусики Кайся Санги Препараты для чрескожной и чресслизистой доставки
PE20061324A1 (es) 2005-04-29 2007-01-15 Centocor Inc Anticuerpos anti-il-6, composiciones, metodos y usos
EP1957535A1 (en) 2005-11-09 2008-08-20 Abbott Laboratories Human bnp immunospecific antibodies
WO2007076115A2 (en) * 2005-12-23 2007-07-05 Arcadia Biosciences, Inc. Nitrogen-efficient monocot plants
CH697825B1 (de) 2006-02-01 2009-02-27 Isofer Ag Auffangzaun für Lawinen Stein- oder Holzschlag.
WO2007119774A1 (ja) 2006-04-13 2007-10-25 Chugai Seiyaku Kabushiki Kaisha タウリントランスポーター遺伝子
US20100233759A1 (en) * 2007-03-15 2010-09-16 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
EP2186905B1 (en) * 2007-08-07 2016-07-13 Chugai Seiyaku Kabushiki Kaisha Method of producing heterogeneous protein
WO2009051109A1 (ja) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
JP5337044B2 (ja) 2007-10-24 2013-11-06 中外製薬株式会社 異種タンパク質製造のための細胞及びそれを用いた製造方法
JP5715050B2 (ja) * 2009-04-22 2015-05-07 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法

Also Published As

Publication number Publication date
TWI463013B (zh) 2014-12-01
BRPI0815036B1 (pt) 2022-09-20
US20140309405A1 (en) 2014-10-16
AU2008284753A1 (en) 2009-02-12
CN101809161A (zh) 2010-08-18
US20100167346A1 (en) 2010-07-01
EP2186905A1 (en) 2010-05-19
KR101577839B1 (ko) 2015-12-15
CA2695849C (en) 2018-10-16
AU2008284753B2 (en) 2014-01-16
CA2695849A1 (en) 2009-02-12
US9284374B2 (en) 2016-03-15
RU2487168C2 (ru) 2013-07-10
EP2186905A4 (en) 2010-09-01
ES2591284T3 (es) 2016-11-25
WO2009020144A1 (ja) 2009-02-12
US20150315624A1 (en) 2015-11-05
JP5337033B2 (ja) 2013-11-06
EP2186905B1 (en) 2016-07-13
MX2010001319A (es) 2010-06-01
CN101809161B (zh) 2014-03-12
TW200920845A (en) 2009-05-16
RU2010108308A (ru) 2011-09-20
HK1143608A1 (zh) 2011-01-07
DK2186905T3 (en) 2016-09-19
US8697397B2 (en) 2014-04-15
KR20100057598A (ko) 2010-05-31
US9499618B2 (en) 2016-11-22
JPWO2009020144A1 (ja) 2010-11-04

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/08/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.