[go: up one dir, main page]

MX2008000072A - Moduladores no esteroides de receptor de progesterona. - Google Patents

Moduladores no esteroides de receptor de progesterona.

Info

Publication number
MX2008000072A
MX2008000072A MX2008000072A MX2008000072A MX2008000072A MX 2008000072 A MX2008000072 A MX 2008000072A MX 2008000072 A MX2008000072 A MX 2008000072A MX 2008000072 A MX2008000072 A MX 2008000072A MX 2008000072 A MX2008000072 A MX 2008000072A
Authority
MX
Mexico
Prior art keywords
receptor modulators
progesterone receptor
therapy
prophylaxis
steroidal progesterone
Prior art date
Application number
MX2008000072A
Other languages
English (en)
Inventor
Peter Droescher
Alexander Hillisch
Norbert Schmees
Wolfgang Schwede
Ulrike Fuhrmann
Carsten Moeller
Anja Schmidt
Ulrich Bothe
Guenter Kaufmann
Lothar Sobek
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of MX2008000072A publication Critical patent/MX2008000072A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente invencion se refiere a moduladores no-esteroides de receptor de progesterona de la formula general (I), al proceso para su preparacion, al uso de los moduladores del receptor de progesterona para la produccion de medicamentos asi como tambien composiciones farmaceuticas que contienen estos compuestos. Los compuestos segun la invencion son apropiados para la terapia y la prevencion de enfermedades ginecologicas tales como endometriosis, leiomiomas utero, hemorragias disfuncionales y dismenorrea y para la terapia y la prevencion de tumores dependientes de hormonas y para el uso para el control de la fertilidad femenina y para la terapia de reemplazo hormonal.
MX2008000072A 2005-06-24 2006-06-22 Moduladores no esteroides de receptor de progesterona. MX2008000072A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005030292A DE102005030292A1 (de) 2005-06-24 2005-06-24 Nichtsteroidale Progesteronrezeptor-Modulatoren
PCT/EP2006/006531 WO2006136461A2 (en) 2005-06-24 2006-06-22 Non-steroidal progesterone receptor modulators

Publications (1)

Publication Number Publication Date
MX2008000072A true MX2008000072A (es) 2008-03-24

Family

ID=37199176

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008000072A MX2008000072A (es) 2005-06-24 2006-06-22 Moduladores no esteroides de receptor de progesterona.

Country Status (22)

Country Link
EP (1) EP1902049A2 (es)
JP (1) JP2008543910A (es)
KR (1) KR20080030622A (es)
CN (1) CN101248066A (es)
AR (1) AR054519A1 (es)
AU (1) AU2006261048A1 (es)
BR (1) BRPI0611903A2 (es)
CA (1) CA2611897A1 (es)
CR (1) CR9598A (es)
DE (1) DE102005030292A1 (es)
DO (1) DOP2006000148A (es)
EA (1) EA200702524A1 (es)
EC (1) ECSP078044A (es)
GT (1) GT200600271A (es)
IL (1) IL188021A0 (es)
MX (1) MX2008000072A (es)
NO (1) NO20080440L (es)
PE (1) PE20070125A1 (es)
TW (1) TW200740778A (es)
UY (1) UY29624A1 (es)
WO (1) WO2006136461A2 (es)
ZA (1) ZA200800690B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY30805A1 (es) * 2006-12-21 2008-07-31 Bayer Schering Pharma Ag Moduladores no esteroides de receptores de progesterona
DE102007032800A1 (de) * 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007058747A1 (de) * 2007-12-05 2009-06-10 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
JP2011519916A (ja) * 2008-07-02 2011-07-14 ファーマコステック カンパニー リミテッド アミド誘導体の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19856475A1 (de) * 1998-11-27 2000-05-31 Schering Ag Nichtsteroidale Entzündungshemmer
EP1344776A1 (en) * 2002-03-11 2003-09-17 Schering Aktiengesellschaft 5- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -phtalide and 6- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -4-methyl-2,3-benzoxazin-1-one derivatives with progesterone receptor modulating activity for use in fertility control, hormone replacement therapy and the treatment of gynecological disorders
RS20050974A (sr) * 2003-07-01 2007-09-21 Schering Aktiengesellschaft, Heterociklično supstituisani pentanol-derivati,postupak za njihovo dobijanje i njihova primena kao supresora zapaljenja

Also Published As

Publication number Publication date
EA200702524A1 (ru) 2008-06-30
IL188021A0 (en) 2008-03-20
DOP2006000148A (es) 2007-07-15
CR9598A (es) 2008-04-09
EP1902049A2 (en) 2008-03-26
UY29624A1 (es) 2007-01-31
PE20070125A1 (es) 2007-02-14
KR20080030622A (ko) 2008-04-04
TW200740778A (en) 2007-11-01
ECSP078044A (es) 2008-01-23
ZA200800690B (en) 2009-09-30
DE102005030292A1 (de) 2007-01-11
GT200600271A (es) 2007-02-05
BRPI0611903A2 (pt) 2010-10-05
JP2008543910A (ja) 2008-12-04
NO20080440L (no) 2008-03-25
CN101248066A (zh) 2008-08-20
AR054519A1 (es) 2007-06-27
CA2611897A1 (en) 2006-12-28
AU2006261048A1 (en) 2006-12-28
WO2006136461A2 (en) 2006-12-28
WO2006136461A3 (en) 2007-03-15

Similar Documents

Publication Publication Date Title
MX2009009581A (es) Indazoles usados para tratar trastornos mediados por el receptor de estrogenos beta.
WO2011009531A3 (de) 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-derivate, verfahren zu ihrer herstellung und ihre verwendung zur behandlung von krankheiten
WO2011009529A3 (de) 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-derivate, verfahren zu ihrer herstellung und ihre verwendung zur behandlung von krankheiten
TN2012000618A1 (en) 6,7-dihydro-5h-benzo[7]annulene derivatives, process for preparation thereof, pharmaceutical preparations comprising them, and the use thereof for production of medicaments
MX2009006540A (es) Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides.
WO2011098437A3 (de) Progesteronrezeptorantagonisten
UA98138C2 (ru) Производные бензамида как модуляторы фолликулостимулирующего гормона
WO2011009534A3 (de) 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-derivate, verfahren zu ihrer herstellung und ihre verwendung zur behandlung von krankheiten
MX2007002393A (es) Compuestos indolicos sustituidos y su uso como moduladores del receptor de 5-hidroxitriptamina 6 (5-ht6).
WO2007016385A3 (en) Use of substituted 5-amino-1h-pyrrole-2-carbonitrile derivatives as progesterone receptor modulators
ECSP078043A (es) Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona
WO2008113851A3 (en) Novel c11 modified retrosteroids as progesterone receptor modulator compounds
MX2008000072A (es) Moduladores no esteroides de receptor de progesterona.
WO2008077647A3 (de) Alpha-aminoalkohole als nichtsteroidale progesteronrezeptor-modulatoren
IL205231A0 (en) Amino arylsulfonamide compounds and their use as 5 - ht6 ligands
GEP20125607B (en) Pyrrolidines
UY29625A1 (es) Uso de moduladores no esteroides de receptores de progesterona
TN2010000007A1 (en) 8-beta- substituted estratrienes as selectively active estrogens
UY30815A1 (es) Moduladores no esteroidales del receptor de progesterona
TH85420B (th) การใช้สารปรับโพรเจสเตอโรนรีเซปเตอร์ชนิดนอน-สเตียรอยด์
UA98126C2 (ru) Производные индазолильного эстера и амида для лечения расстройств, опосредованных глюкокортикоидным рецептором

Legal Events

Date Code Title Description
FA Abandonment or withdrawal