MA32275B1 - Preparations orales et injectables de composes de tetracycline - Google Patents
Preparations orales et injectables de composes de tetracyclineInfo
- Publication number
- MA32275B1 MA32275B1 MA33281A MA33281A MA32275B1 MA 32275 B1 MA32275 B1 MA 32275B1 MA 33281 A MA33281 A MA 33281A MA 33281 A MA33281 A MA 33281A MA 32275 B1 MA32275 B1 MA 32275B1
- Authority
- MA
- Morocco
- Prior art keywords
- oral
- injectable preparations
- tetracycline compounds
- preparations
- relates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La présente invention concerne des préparations injectables et orales d'un composé de tétracycline. Dans un mode de réalisation, l'invention concerne une préparation orale de composé de 9-aminométhyl tétracycline, ou de son sel, sous forme de comprimé ou de capsule. Les préparations peuvent être utilisées, par exemple, pour traiter des infections.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4039808P | 2008-03-28 | 2008-03-28 | |
| PCT/US2009/001973 WO2009120389A1 (fr) | 2008-03-28 | 2009-03-30 | Préparations orales et injectables de composés de tétracycline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA32275B1 true MA32275B1 (fr) | 2011-05-02 |
Family
ID=41114256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA33281A MA32275B1 (fr) | 2008-03-28 | 2010-10-25 | Preparations orales et injectables de composes de tetracycline |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US9314475B2 (fr) |
| EP (3) | EP3348258B1 (fr) |
| JP (8) | JP2011515473A (fr) |
| KR (3) | KR101746228B1 (fr) |
| CN (1) | CN102046177B (fr) |
| AU (1) | AU2009229174A1 (fr) |
| BR (2) | BRPI0909211B8 (fr) |
| CA (2) | CA2719751C (fr) |
| CL (1) | CL2010000281A1 (fr) |
| CO (1) | CO6300935A2 (fr) |
| CY (2) | CY1120240T1 (fr) |
| DK (2) | DK3348258T3 (fr) |
| EC (1) | ECSP10010576A (fr) |
| ES (2) | ES2674708T3 (fr) |
| HR (2) | HRP20180836T1 (fr) |
| HU (2) | HUE052201T2 (fr) |
| IL (1) | IL208440A0 (fr) |
| LT (2) | LT3348258T (fr) |
| MA (1) | MA32275B1 (fr) |
| MX (1) | MX2010010585A (fr) |
| NO (1) | NO2271348T3 (fr) |
| NZ (1) | NZ588428A (fr) |
| PL (2) | PL3348258T3 (fr) |
| PT (2) | PT2271348T (fr) |
| RU (1) | RU2010144130A (fr) |
| SI (2) | SI2271348T1 (fr) |
| TR (1) | TR201806893T4 (fr) |
| UA (2) | UA122762C2 (fr) |
| WO (1) | WO2009120389A1 (fr) |
| ZA (1) | ZA201007013B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0908951A2 (pt) | 2008-03-05 | 2017-01-17 | Paratek Pharm Innc | compostos de minociclina e método de uso dos mesmos |
| TW202332671A (zh) * | 2008-05-19 | 2023-08-16 | 美商Prtk Spv2公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
| ES2613738T3 (es) | 2010-05-12 | 2017-05-25 | Rempex Pharmaceuticals, Inc. | Composiciones de tetraciclina |
| US10238670B2 (en) * | 2016-05-02 | 2019-03-26 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl minocycline compounds and methods of use thereof in urinary tract infection (UTI) treatment |
| US10166912B2 (en) | 2016-08-19 | 2019-01-01 | Sl Corporation | Automotive LED driving apparatus |
| SG10201913599RA (en) | 2016-11-01 | 2020-02-27 | Paratek Pharm Innc | 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp) |
| CN113164456A (zh) * | 2018-09-04 | 2021-07-23 | 帕拉特克药品公司 | 使用四环素化合物治疗分枝杆菌感染的方法 |
| MX2022008103A (es) * | 2019-12-30 | 2022-09-19 | Deciphera Pharmaceuticals Llc | Formulaciones de inhibidores de la cinasa amorfa y metodos de estas. |
| PT117254B (pt) | 2021-05-26 | 2024-04-18 | Hovione Farm S A | Método de síntese de compostos 9-aminometil tetraciclinas |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2699054A (en) | 1953-10-09 | 1955-01-11 | Lloyd H Conover | Tetracycline |
| US2712517A (en) | 1954-03-03 | 1955-07-05 | Bristol Lab Inc | Production of tetracycline and substituted tetracyclines |
| US3019173A (en) | 1956-06-04 | 1962-01-30 | American Cyanamid Co | Method for preparing tetracycline |
| US2990331A (en) | 1956-11-23 | 1961-06-27 | Pfizer & Co C | Stable solutions of salts of tetracyclines for parenteral administration |
| US3005023A (en) | 1957-04-05 | 1961-10-17 | American Cyanamid Co | Production of tetracycline |
| US2980584A (en) | 1957-10-29 | 1961-04-18 | Pfizer & Co C | Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation |
| US2886595A (en) | 1958-09-30 | 1959-05-12 | Bristol Lab Inc | Tetracycline recovery |
| US3062717A (en) | 1958-12-11 | 1962-11-06 | Pfizer & Co C | Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation |
| US3019260A (en) | 1959-05-13 | 1962-01-30 | American Cyanamid Co | Process for the catalytic reduction of 6-hydroxy hydronaphthacenes |
| FR1430859A (fr) | 1960-05-23 | 1966-05-25 | ||
| US3165531A (en) | 1962-03-08 | 1965-01-12 | Pfizer & Co C | 13-substituted-6-deoxytetracyclines and process utilizing the same |
| US3301899A (en) | 1963-11-27 | 1967-01-31 | Bristol Myers Co | Purification of tetracycline |
| US3454697A (en) | 1965-06-08 | 1969-07-08 | American Cyanamid Co | Tetracycline antibiotic compositions for oral use |
| NL6607516A (fr) | 1966-05-31 | 1967-12-01 | ||
| DE1767891C3 (de) | 1968-06-28 | 1980-10-30 | Pfizer | Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat |
| US3957980A (en) | 1972-10-26 | 1976-05-18 | Pfizer Inc. | Doxycycline parenteral compositions |
| DE2442829A1 (de) | 1974-09-06 | 1976-03-18 | Merck Patent Gmbh | Tetracyclische verbindungen und verfahren zu ihrer herstellung |
| US4018889A (en) | 1976-01-02 | 1977-04-19 | Pfizer Inc. | Oxytetracycline compositions |
| US4126680A (en) | 1977-04-27 | 1978-11-21 | Pfizer Inc. | Tetracycline antibiotic compositions |
| US4837030A (en) | 1987-10-06 | 1989-06-06 | American Cyanamid Company | Novel controlled release formulations of tetracycline compounds |
| US5494903A (en) | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
| EP0536515B1 (fr) | 1991-10-04 | 2001-12-19 | American Cyanamid Company | 6-Deméthyl-6-déoxy-tétracyclines substituées en 7 et substituées en 9 par un groupe amino substitué |
| US6465431B1 (en) * | 1999-11-17 | 2002-10-15 | Boston Life Sciences, Inc. | Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis |
| AU9540898A (en) | 1997-08-29 | 1999-03-22 | Dsm N.V. | Granules free of excipients |
| KR100252699B1 (ko) * | 1998-03-17 | 2000-12-01 | 강재헌 | 치주염 치료용 미노사이클린 조성물 |
| JP5060685B2 (ja) | 1998-11-18 | 2012-10-31 | ガルデマ ラボラトリーズ インコーポレイテッド | 新規4−デジメチルアミノテトラサイクリン誘導体 |
| US6448323B1 (en) | 1999-07-09 | 2002-09-10 | Bpsi Holdings, Inc. | Film coatings and film coating compositions based on polyvinyl alcohol |
| JP4516711B2 (ja) * | 1999-12-28 | 2010-08-04 | 中外製薬株式会社 | 安定な抗体組成物及び注射製剤 |
| AU8638801A (en) * | 2000-07-07 | 2002-01-21 | Tufts College | 9-substituted minocycline compounds |
| EP1955996A1 (fr) | 2001-03-13 | 2008-08-13 | Paratek Pharmaceuticals, Inc. | Composés de tétracycline substitués en position 7, 9 |
| US7553828B2 (en) * | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds |
| WO2002072031A2 (fr) * | 2001-03-14 | 2002-09-19 | Paratek Pharmaceuticals, Inc. | Composes de tetracycline substitue utilises en tant qu'antifongiques synergiques |
| AU2002256092C1 (en) * | 2001-04-05 | 2009-10-15 | Collagenex Pharmaceuticals, Inc. | Controlled delivery of tetracycline compounds and tetracycline derivatives |
| US8088820B2 (en) * | 2001-04-24 | 2012-01-03 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for the treatment of malaria |
| EP2327409A1 (fr) * | 2001-07-13 | 2011-06-01 | Paratek Pharmaceuticals, Inc. | Tetracycline avec activité pharmacéutique |
| CN101307017A (zh) | 2002-03-08 | 2008-11-19 | 帕拉特克药品公司 | 氨基-甲基取代的四环素类化合物 |
| CN1390550A (zh) * | 2002-07-25 | 2003-01-15 | 于航 | 盐酸米诺环素冻干粉针剂及其制备方法 |
| WO2004038000A2 (fr) * | 2002-10-24 | 2004-05-06 | Paratek Pharmaceuticals, Inc. | Procedes d'utilisation de composes tetracycline substituee pour moduler l'arn |
| EP1556007A4 (fr) * | 2002-10-24 | 2008-12-17 | Paratek Pharm Innc | Composes tetracycline substituee servant au traitement du paludisme |
| US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
| WO2004064728A2 (fr) * | 2003-01-16 | 2004-08-05 | Paratek Pharmaceuticals, Inc. | Composes de tetracycline possedant des activites therapeutiques ciblees |
| JP4711947B2 (ja) * | 2003-02-03 | 2011-06-29 | ネオファーム、インコーポレイティッド | 安定な濾過滅菌性リポソームに被包化されたタキサン及び他の抗腫瘍剤 |
| WO2004078111A2 (fr) * | 2003-03-06 | 2004-09-16 | Ranbaxy Laboratories Limited | Compositions de minocycline a liberation prolongee et leurs procedes de preparation |
| WO2004091513A2 (fr) * | 2003-04-10 | 2004-10-28 | Paratek Pharmaceuticals, Inc. | Composes de la minocycline substitues par 9-aminomethyle |
| US20050143352A1 (en) * | 2003-07-09 | 2005-06-30 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| US20060287283A1 (en) | 2003-07-09 | 2006-12-21 | Paratek Pharmaceuticals, Inc. | Prodrugs of 9-aminomethyl tetracycline compounds |
| US20050137174A1 (en) * | 2003-07-09 | 2005-06-23 | Paratek Pharmaceuticals, Inc. | Prodrugs of 9-aminomethyl tetracycline compounds |
| US7786099B2 (en) * | 2004-01-15 | 2010-08-31 | Paratek Pharmaceuticals, Inc. | Aromatic a-ring derivatives of tetracycline compounds |
| GB2414668B (en) * | 2004-06-03 | 2009-07-29 | Dexcel Ltd | Tetracycline modified release delivery system |
| JP4972081B2 (ja) * | 2005-03-14 | 2012-07-11 | ワイス・エルエルシー | チゲサイクリン組成物および調製方法 |
| CA2639406A1 (fr) * | 2006-01-24 | 2007-08-02 | Paratek Pharmaceuticals, Inc. | Procede permettant d'accroitre la biodisponibilite orale de tetracyclines |
| US20090246276A1 (en) * | 2008-01-28 | 2009-10-01 | Graham Jackson | Pharmaceutical Compositions |
| BRPI0908951A2 (pt) * | 2008-03-05 | 2017-01-17 | Paratek Pharm Innc | compostos de minociclina e método de uso dos mesmos |
-
2009
- 2009-03-03 PT PT97238968T patent/PT2271348T/pt unknown
- 2009-03-30 ES ES09723896.8T patent/ES2674708T3/es active Active
- 2009-03-30 RU RU2010144130/15A patent/RU2010144130A/ru not_active Application Discontinuation
- 2009-03-30 KR KR1020107024076A patent/KR101746228B1/ko active Active
- 2009-03-30 PL PL18158017T patent/PL3348258T3/pl unknown
- 2009-03-30 DK DK18158017.6T patent/DK3348258T3/da active
- 2009-03-30 JP JP2011501848A patent/JP2011515473A/ja active Pending
- 2009-03-30 AU AU2009229174A patent/AU2009229174A1/en not_active Abandoned
- 2009-03-30 BR BRPI0909211A patent/BRPI0909211B8/pt active IP Right Grant
- 2009-03-30 CN CN2009801191056A patent/CN102046177B/zh not_active Ceased
- 2009-03-30 DK DK09723896.8T patent/DK2271348T3/en active
- 2009-03-30 ES ES18158017T patent/ES2836448T3/es active Active
- 2009-03-30 HU HUE18158017A patent/HUE052201T2/hu unknown
- 2009-03-30 BR BR122020011180A patent/BR122020011180B8/pt active IP Right Grant
- 2009-03-30 KR KR1020167023203A patent/KR101835574B1/ko active Active
- 2009-03-30 EP EP18158017.6A patent/EP3348258B1/fr active Active
- 2009-03-30 SI SI200931826T patent/SI2271348T1/en unknown
- 2009-03-30 LT LTEP18158017.6T patent/LT3348258T/lt unknown
- 2009-03-30 UA UAA201505310A patent/UA122762C2/uk unknown
- 2009-03-30 HR HRP20180836TT patent/HRP20180836T1/hr unknown
- 2009-03-30 SI SI200932097T patent/SI3348258T1/sl unknown
- 2009-03-30 CA CA2719751A patent/CA2719751C/fr active Active
- 2009-03-30 EP EP20189488.8A patent/EP3789030A1/fr active Pending
- 2009-03-30 WO PCT/US2009/001973 patent/WO2009120389A1/fr not_active Ceased
- 2009-03-30 PL PL09723896T patent/PL2271348T3/pl unknown
- 2009-03-30 TR TR2018/06893T patent/TR201806893T4/tr unknown
- 2009-03-30 NZ NZ588428A patent/NZ588428A/xx not_active IP Right Cessation
- 2009-03-30 HU HUE09723896A patent/HUE038257T2/hu unknown
- 2009-03-30 NO NO09723896A patent/NO2271348T3/no unknown
- 2009-03-30 MX MX2010010585A patent/MX2010010585A/es not_active Application Discontinuation
- 2009-03-30 UA UAA201012435A patent/UA109627C2/ru unknown
- 2009-03-30 LT LTEP09723896.8T patent/LT2271348T/lt unknown
- 2009-03-30 US US12/414,615 patent/US9314475B2/en active Active
- 2009-03-30 CA CA2984301A patent/CA2984301C/fr active Active
- 2009-03-30 EP EP09723896.8A patent/EP2271348B1/fr active Active
- 2009-03-30 PT PT181580176T patent/PT3348258T/pt unknown
- 2009-03-30 KR KR1020187005923A patent/KR101893740B1/ko active Active
-
2010
- 2010-03-29 CL CL2010000281A patent/CL2010000281A1/es unknown
- 2010-10-01 ZA ZA2010/07013A patent/ZA201007013B/en unknown
- 2010-10-03 IL IL208440A patent/IL208440A0/en unknown
- 2010-10-25 MA MA33281A patent/MA32275B1/fr unknown
- 2010-10-26 CO CO10132833A patent/CO6300935A2/es not_active Application Discontinuation
- 2010-10-27 EC EC2010010576A patent/ECSP10010576A/es unknown
-
2014
- 2014-07-28 JP JP2014152471A patent/JP5940119B2/ja active Active
-
2016
- 2016-03-07 US US15/062,499 patent/US20160279151A1/en not_active Abandoned
- 2016-05-17 JP JP2016098578A patent/JP6412521B2/ja active Active
-
2018
- 2018-05-23 CY CY20181100542T patent/CY1120240T1/el unknown
- 2018-09-28 JP JP2018183953A patent/JP6577645B2/ja active Active
-
2019
- 2019-08-22 JP JP2019151857A patent/JP2019196408A/ja active Pending
-
2020
- 2020-09-24 CY CY20201100908T patent/CY1123382T1/el unknown
- 2020-11-26 HR HRP20201883TT patent/HRP20201883T1/hr unknown
-
2021
- 2021-07-28 JP JP2021122850A patent/JP2021167355A/ja active Pending
-
2023
- 2023-08-16 JP JP2023132396A patent/JP2023144043A/ja active Pending
-
2025
- 2025-07-23 JP JP2025123003A patent/JP2025137721A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA32275B1 (fr) | Preparations orales et injectables de composes de tetracycline | |
| MA51204B1 (fr) | Formes pharmaceutiques comprenant un inhibiteur de la kallicréine plasmatique | |
| MA46452B1 (fr) | Composés de benzo[b]thiophéne en tant qu'agonistes de sting | |
| MY160703A (en) | Crystalline forms of (r) -5- [3-chloro-4-(2,3-dihydroxy) - benz [z] ylidene] -2- ([z]-propylimino) -3-0-tolyl-thiazolidin-4-one | |
| UA96449C2 (en) | Stable laquinimod preparations | |
| MA35753B1 (fr) | Aryl-dihydropyridinones et pipéridinones en tant qu'inhibiteurs de mgat2 | |
| EA200970916A1 (ru) | Соединения 5,6-дигидро-1н-пиридин-2-она | |
| MA30807B1 (fr) | Compositions pharmaceutiques. | |
| MA32568B1 (fr) | Formulations pharmaceutiques contenant des ligands de recepteur de dopamine | |
| EA201200096A1 (ru) | Фармацевтическая композиция ингибитора протеазы вируса гепатита c | |
| MY145074A (en) | Thiazolidin-4-one derivatives | |
| UA107582C2 (uk) | Таблетований препарат (4'-трифторметилфеніл)аміду (z)-2-ціано-гідроксибут-2-еноєвої кислоти з поліпшеною стійкістю | |
| EA201100795A1 (ru) | Фармацевтическая композиция эффективного ингибитора всг для перорального введения | |
| EA201071218A1 (ru) | Улучшенные композиции для активных фармацевтических компонентов с плохой проницаемостью | |
| TW200800967A (en) | Benzimidazole thiophene compounds | |
| EA201101118A1 (ru) | Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина | |
| CA2672094C (fr) | Procedes et appareil pour l'identification de matiere dans des donnees de visualisation | |
| MA33679B1 (fr) | Derives de 2-oxo-1-pyrrolidinyle imidazothiadiazole | |
| ATE487720T1 (de) | 5,6,7,8-tetrahydropteridin-derivate als hsp90- hemmer | |
| EA201591649A1 (ru) | Составы с органическими соединениями | |
| MA34806B1 (fr) | Compositions pharmaceutiques | |
| AR058085A1 (es) | Sal de dihidrogeno fosfato de un antagonista del receptor de prostaglandina d2. composiciones farmaceuticas. | |
| MA38679A1 (fr) | Modulateurs du récepteur de cxcr7 | |
| PH12017501397A1 (en) | (2s, 4r)-5-(5`-chloro-2`-fluorobiphenyl-4-yl)-4-(ethoxyoxalylamino)-2-hydroxymethyl-2-methylpentanoic acid as neprilysin inhibitor | |
| UA106200C2 (uk) | Заміщені похідні оксіндолу та їхнє застосування для лікування захворювань, залежних від вазопресину |