[go: up one dir, main page]

BRPI0909211A2 - formulação orais e injetáveis de composto de tetraciclina - Google Patents

formulação orais e injetáveis de composto de tetraciclina

Info

Publication number
BRPI0909211A2
BRPI0909211A2 BRPI0909211A BRPI0909211A BRPI0909211A2 BR PI0909211 A2 BRPI0909211 A2 BR PI0909211A2 BR PI0909211 A BRPI0909211 A BR PI0909211A BR PI0909211 A BRPI0909211 A BR PI0909211A BR PI0909211 A2 BRPI0909211 A2 BR PI0909211A2
Authority
BR
Brazil
Prior art keywords
oral
injectable formulations
tetracycline compound
tetracycline
compound
Prior art date
Application number
BRPI0909211A
Other languages
English (en)
Inventor
Sean Johnston
Original Assignee
Paratek Pharm Innc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41114256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0909211(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Paratek Pharm Innc filed Critical Paratek Pharm Innc
Priority to BR122020011180A priority Critical patent/BR122020011180B8/pt
Publication of BRPI0909211A2 publication Critical patent/BRPI0909211A2/pt
Publication of BRPI0909211B1 publication Critical patent/BRPI0909211B1/pt
Publication of BRPI0909211B8 publication Critical patent/BRPI0909211B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0909211A 2008-03-28 2009-03-30 formulação oral em forma de comprimido de compostos de tetraciclina BRPI0909211B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122020011180A BR122020011180B8 (pt) 2008-03-28 2009-03-30 formulações injetáveis de compostos de tetraciclina

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4039808P 2008-03-28 2008-03-28
US61/040,398 2008-03-28
PCT/US2009/001973 WO2009120389A1 (en) 2008-03-28 2009-03-30 Oral and injectable formulations of tetracycline compounds

Publications (3)

Publication Number Publication Date
BRPI0909211A2 true BRPI0909211A2 (pt) 2016-11-29
BRPI0909211B1 BRPI0909211B1 (pt) 2020-08-25
BRPI0909211B8 BRPI0909211B8 (pt) 2021-05-25

Family

ID=41114256

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0909211A BRPI0909211B8 (pt) 2008-03-28 2009-03-30 formulação oral em forma de comprimido de compostos de tetraciclina
BR122020011180A BR122020011180B8 (pt) 2008-03-28 2009-03-30 formulações injetáveis de compostos de tetraciclina

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122020011180A BR122020011180B8 (pt) 2008-03-28 2009-03-30 formulações injetáveis de compostos de tetraciclina

Country Status (30)

Country Link
US (2) US9314475B2 (pt)
EP (3) EP3348258B1 (pt)
JP (8) JP2011515473A (pt)
KR (3) KR101746228B1 (pt)
CN (1) CN102046177B (pt)
AU (1) AU2009229174A1 (pt)
BR (2) BRPI0909211B8 (pt)
CA (2) CA2719751C (pt)
CL (1) CL2010000281A1 (pt)
CO (1) CO6300935A2 (pt)
CY (2) CY1120240T1 (pt)
DK (2) DK3348258T3 (pt)
EC (1) ECSP10010576A (pt)
ES (2) ES2674708T3 (pt)
HR (2) HRP20180836T1 (pt)
HU (2) HUE052201T2 (pt)
IL (1) IL208440A0 (pt)
LT (2) LT3348258T (pt)
MA (1) MA32275B1 (pt)
MX (1) MX2010010585A (pt)
NO (1) NO2271348T3 (pt)
NZ (1) NZ588428A (pt)
PL (2) PL3348258T3 (pt)
PT (2) PT2271348T (pt)
RU (1) RU2010144130A (pt)
SI (2) SI2271348T1 (pt)
TR (1) TR201806893T4 (pt)
UA (2) UA122762C2 (pt)
WO (1) WO2009120389A1 (pt)
ZA (1) ZA201007013B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0908951A2 (pt) 2008-03-05 2017-01-17 Paratek Pharm Innc compostos de minociclina e método de uso dos mesmos
TW202332671A (zh) * 2008-05-19 2023-08-16 美商Prtk Spv2公司 四環素化合物之甲苯磺酸鹽及同素異形體
ES2613738T3 (es) 2010-05-12 2017-05-25 Rempex Pharmaceuticals, Inc. Composiciones de tetraciclina
US10238670B2 (en) * 2016-05-02 2019-03-26 Paratek Pharmaceuticals, Inc. 9-aminomethyl minocycline compounds and methods of use thereof in urinary tract infection (UTI) treatment
US10166912B2 (en) 2016-08-19 2019-01-01 Sl Corporation Automotive LED driving apparatus
SG10201913599RA (en) 2016-11-01 2020-02-27 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
CN113164456A (zh) * 2018-09-04 2021-07-23 帕拉特克药品公司 使用四环素化合物治疗分枝杆菌感染的方法
MX2022008103A (es) * 2019-12-30 2022-09-19 Deciphera Pharmaceuticals Llc Formulaciones de inhibidores de la cinasa amorfa y metodos de estas.
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2699054A (en) 1953-10-09 1955-01-11 Lloyd H Conover Tetracycline
US2712517A (en) 1954-03-03 1955-07-05 Bristol Lab Inc Production of tetracycline and substituted tetracyclines
US3019173A (en) 1956-06-04 1962-01-30 American Cyanamid Co Method for preparing tetracycline
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US3005023A (en) 1957-04-05 1961-10-17 American Cyanamid Co Production of tetracycline
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US2886595A (en) 1958-09-30 1959-05-12 Bristol Lab Inc Tetracycline recovery
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3019260A (en) 1959-05-13 1962-01-30 American Cyanamid Co Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
FR1430859A (pt) 1960-05-23 1966-05-25
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3301899A (en) 1963-11-27 1967-01-31 Bristol Myers Co Purification of tetracycline
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (pt) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
US4837030A (en) 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
EP0536515B1 (en) 1991-10-04 2001-12-19 American Cyanamid Company Novel 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US6465431B1 (en) * 1999-11-17 2002-10-15 Boston Life Sciences, Inc. Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis
AU9540898A (en) 1997-08-29 1999-03-22 Dsm N.V. Granules free of excipients
KR100252699B1 (ko) * 1998-03-17 2000-12-01 강재헌 치주염 치료용 미노사이클린 조성물
JP5060685B2 (ja) 1998-11-18 2012-10-31 ガルデマ ラボラトリーズ インコーポレイテッド 新規4−デジメチルアミノテトラサイクリン誘導体
US6448323B1 (en) 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
JP4516711B2 (ja) * 1999-12-28 2010-08-04 中外製薬株式会社 安定な抗体組成物及び注射製剤
AU8638801A (en) * 2000-07-07 2002-01-21 Tufts College 9-substituted minocycline compounds
EP1955996A1 (en) 2001-03-13 2008-08-13 Paratek Pharmaceuticals, Inc. 7, 9-Substituted tetracycline compounds
US7553828B2 (en) * 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
WO2002072031A2 (en) * 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2327409A1 (en) * 2001-07-13 2011-06-01 Paratek Pharmaceuticals, Inc. Tetracycline compound having target therapeutic activities
CN101307017A (zh) 2002-03-08 2008-11-19 帕拉特克药品公司 氨基-甲基取代的四环素类化合物
CN1390550A (zh) * 2002-07-25 2003-01-15 于航 盐酸米诺环素冻干粉针剂及其制备方法
WO2004038000A2 (en) * 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Methods of using substituted tetracycline compounds to modulate rna
EP1556007A4 (en) * 2002-10-24 2008-12-17 Paratek Pharm Innc SUBSTITUTED TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF MALARIA
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
WO2004064728A2 (en) * 2003-01-16 2004-08-05 Paratek Pharmaceuticals, Inc. Use of specific tetracycline compounds in therapy
JP4711947B2 (ja) * 2003-02-03 2011-06-29 ネオファーム、インコーポレイティッド 安定な濾過滅菌性リポソームに被包化されたタキサン及び他の抗腫瘍剤
WO2004078111A2 (en) * 2003-03-06 2004-09-16 Ranbaxy Laboratories Limited Extended release minocycline compositions and processes for their preparation
WO2004091513A2 (en) * 2003-04-10 2004-10-28 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
US20050143352A1 (en) * 2003-07-09 2005-06-30 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US20060287283A1 (en) 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20050137174A1 (en) * 2003-07-09 2005-06-23 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US7786099B2 (en) * 2004-01-15 2010-08-31 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
JP4972081B2 (ja) * 2005-03-14 2012-07-11 ワイス・エルエルシー チゲサイクリン組成物および調製方法
CA2639406A1 (en) * 2006-01-24 2007-08-02 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
US20090246276A1 (en) * 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
BRPI0908951A2 (pt) * 2008-03-05 2017-01-17 Paratek Pharm Innc compostos de minociclina e método de uso dos mesmos

Also Published As

Publication number Publication date
PL2271348T3 (pl) 2018-08-31
UA122762C2 (uk) 2021-01-06
KR101835574B1 (ko) 2018-03-08
JP5940119B2 (ja) 2016-06-29
MA32275B1 (fr) 2011-05-02
ES2836448T3 (es) 2021-06-25
PT2271348T (pt) 2018-04-16
JP2011515473A (ja) 2011-05-19
KR101746228B1 (ko) 2017-06-12
HRP20180836T1 (hr) 2018-07-27
BRPI0909211B8 (pt) 2021-05-25
AU2009229174A1 (en) 2009-10-01
BRPI0909211B1 (pt) 2020-08-25
JP2023144043A (ja) 2023-10-06
JP2016145260A (ja) 2016-08-12
MX2010010585A (es) 2010-11-09
EP2271348B1 (en) 2018-03-28
CN102046177B (zh) 2012-12-19
UA109627C2 (uk) 2015-09-25
SI3348258T1 (sl) 2020-12-31
US9314475B2 (en) 2016-04-19
US20160279151A1 (en) 2016-09-29
ZA201007013B (en) 2013-11-27
JP2014221820A (ja) 2014-11-27
ES2674708T3 (es) 2018-07-03
BR122020011180B1 (pt) 2021-03-23
KR20160105532A (ko) 2016-09-06
JP6412521B2 (ja) 2018-10-24
KR20180026799A (ko) 2018-03-13
WO2009120389A1 (en) 2009-10-01
CL2010000281A1 (es) 2012-03-30
NO2271348T3 (pt) 2018-08-25
CY1123382T1 (el) 2021-12-31
NZ588428A (en) 2012-08-31
ECSP10010576A (es) 2010-12-30
RU2010144130A (ru) 2012-05-10
TR201806893T4 (tr) 2018-06-21
CO6300935A2 (es) 2011-07-21
US20100056638A1 (en) 2010-03-04
WO2009120389A8 (en) 2010-05-14
EP3348258B1 (en) 2020-09-09
BR122020011180B8 (pt) 2021-07-27
IL208440A0 (en) 2010-12-30
DK2271348T3 (en) 2018-06-14
HUE052201T2 (hu) 2021-04-28
CY1120240T1 (el) 2019-07-10
CA2984301C (en) 2020-10-27
CA2719751A1 (en) 2009-10-01
JP2018203778A (ja) 2018-12-27
EP3789030A1 (en) 2021-03-10
JP2021167355A (ja) 2021-10-21
HUE038257T2 (hu) 2018-10-29
PT3348258T (pt) 2020-11-25
CA2719751C (en) 2018-01-02
JP6577645B2 (ja) 2019-09-18
HRP20201883T1 (hr) 2021-01-22
KR101893740B1 (ko) 2018-08-30
LT2271348T (lt) 2018-06-25
EP2271348A1 (en) 2011-01-12
JP2025137721A (ja) 2025-09-19
CN102046177A (zh) 2011-05-04
EP3348258A1 (en) 2018-07-18
CA2984301A1 (en) 2009-10-01
KR20110008057A (ko) 2011-01-25
JP2019196408A (ja) 2019-11-14
LT3348258T (lt) 2020-12-10
SI2271348T1 (en) 2018-08-31
HK1257928A1 (en) 2019-11-01
EP2271348A4 (en) 2011-05-25
PL3348258T3 (pl) 2021-03-08
DK3348258T3 (da) 2020-12-07

Similar Documents

Publication Publication Date Title
LT3692983T (lt) Citidino analogų peroralinės kompozicijos ir jų naudojimo būdai
BRPI1011587A2 (pt) compostos e composições terapèuticas
BRPI0914427B8 (pt) composição dental endurecível
BRPI0914713A2 (pt) composição para cuidado oral
BRPI0906980A2 (pt) Composição de derivados e maleatados
EP2240022A4 (en) PHARMACEUTICAL COMPOSITIONS
BRPI0909211A2 (pt) formulação orais e injetáveis de composto de tetraciclina
BRPI0923836A2 (pt) Composições farmacêuticas orais contendo opióide e métodos
EP2373681A4 (en) PHARMACEUTICAL COMPOSITIONS
EP2241304A4 (en) ORAL DENTAL COMPOSITION
BRPI0918206A2 (pt) derivados de animoéster e composição medicinal destes
BRPI0907077A2 (pt) métodos e composições para administração oral de proteínas
BRPI0913521A2 (pt) composição dental endurecível e artigo dental
LT2966175T (lt) Farmacinės kompozicijos turinčios korteksolono-17-alfa-propionato
EP2335669A4 (en) COMPOSITION FOR MEANS FOR DESENSIBILIZING TEETH
BRPI0908132A2 (pt) Composto de benzodiazepina e composição farmacêutica
EP2236149A4 (en) MEDICAL COMPOSITION
BRPI0913398A2 (pt) composição e métodos de adesivo para dentaduras
EP2305205A4 (en) COMPOSITION FOR TEETH
EP2341773A4 (en) PHARMACEUTICAL COMPOSITIONS FROM ATORVASTATIN
SMT201400053B (it) Forme farmaceutiche orali di bendamustina
EP2185112A4 (en) Stabilized therapeutic compositions and formulations
BRPI0913610A2 (pt) métodos e composições para tratamento bucal
BRPI1007515A2 (pt) formulações orais sólidas de uma piridopirimidinona
EP2310009A4 (en) PARENTERAL AND ORAL ADMINISTRATIVE FORMULATIONS FROM BENZIMIDAZOLENE

Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority

Free format text: PERDA DA PRIORIDADE US 61/040,398 DE 28/03/2008 REIVINDICADA NO PCT/US2009/001973 POR NAO CUMPRIMENTO DA EXIGENCIA PUBLICADA NA RPI 2389 DE 18/10/2016 DE MANEIRA SATISFATORIA. O DIREITO DE PRIORIDADE NAO PODE SER EXTRAPOLADO DE UM PEDIDO PARA OUTRO, DESTA FORMA, A CESSAO ENVIADA PARA O PEDIDO DE PATENTE US 12/414,612 DE 30/03/2009, MESMO ESTE REIVINDICANDO A PRIORIDADE DO PEDIDO US 61/040,398 DE 28/03/2008, NAO PODE SER CONSIDERADA VALIDA.

B12F Other appeals [chapter 12.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 25/08/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/03/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF