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MA30807B1 - Compositions pharmaceutiques. - Google Patents

Compositions pharmaceutiques.

Info

Publication number
MA30807B1
MA30807B1 MA31809A MA31809A MA30807B1 MA 30807 B1 MA30807 B1 MA 30807B1 MA 31809 A MA31809 A MA 31809A MA 31809 A MA31809 A MA 31809A MA 30807 B1 MA30807 B1 MA 30807B1
Authority
MA
Morocco
Prior art keywords
pharmaceutical compositions
pellets
salt
produced
pharmaceutically acceptable
Prior art date
Application number
MA31809A
Other languages
English (en)
Inventor
Nathalie Bruneau
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37684496&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA30807(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA30807B1 publication Critical patent/MA30807B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE UNE COMPOSITION PHARMACEUTIQUE, EN PARTICULIER DES CAPSULES, COMPRENANT DES GRANULÉS CONTENANT DU NILOTINIB OU UN SEL DE CELUI-CI, AINSI QU'AU MOINS UN EXCIPIENT PHARMACEUTIQUEMENT ACCEPTABLE. CES GRANULÉS PEUVENT ÊTRE PRODUITS PAR UN PROCÉDÉ DE GRANULATION PAR VOIE HUMIDE.
MA31809A 2006-09-27 2009-04-22 Compositions pharmaceutiques. MA30807B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121371A EP1923053A1 (fr) 2006-09-27 2006-09-27 Composition pharmaceutique comprenant de la nilotinib ou son sel

Publications (1)

Publication Number Publication Date
MA30807B1 true MA30807B1 (fr) 2009-10-01

Family

ID=37684496

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31809A MA30807B1 (fr) 2006-09-27 2009-04-22 Compositions pharmaceutiques.

Country Status (34)

Country Link
US (2) US8293756B2 (fr)
EP (4) EP1923053A1 (fr)
JP (2) JP5567340B2 (fr)
KR (2) KR101598747B1 (fr)
CN (2) CN101516344A (fr)
AR (1) AR062980A1 (fr)
AU (1) AU2007301977B2 (fr)
BR (1) BRPI0719438B1 (fr)
CA (1) CA2662571C (fr)
CL (1) CL2007002766A1 (fr)
CO (1) CO6160288A2 (fr)
CY (2) CY1117021T1 (fr)
DK (2) DK2068839T3 (fr)
ES (3) ES2957912T3 (fr)
FI (2) FI2068839T4 (fr)
HR (2) HRP20151383T4 (fr)
HU (2) HUE063083T2 (fr)
IL (1) IL197496A (fr)
JO (1) JO3757B1 (fr)
LT (1) LT3984528T (fr)
MA (1) MA30807B1 (fr)
MX (1) MX2009003184A (fr)
MY (1) MY148237A (fr)
NO (2) NO347404B1 (fr)
NZ (1) NZ575317A (fr)
PE (2) PE20081379A1 (fr)
PL (2) PL2068839T5 (fr)
PT (2) PT3984528T (fr)
RU (1) RU2469707C2 (fr)
SI (2) SI2068839T2 (fr)
TN (1) TN2009000093A1 (fr)
TW (3) TWI540128B (fr)
WO (1) WO2008037716A2 (fr)
ZA (1) ZA200901511B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1923053A1 (fr) 2006-09-27 2008-05-21 Novartis AG Composition pharmaceutique comprenant de la nilotinib ou son sel
WO2011036305A2 (fr) 2009-09-28 2011-03-31 Medizinische Universität Wien Nouvelle utilisation des inhibiteurs de pdgf-bêta
KR20120099650A (ko) 2009-10-23 2012-09-11 노파르티스 아게 Ｂｃｒ-ａｂｌ, ｃ-ｋｉｔ, ｄｄｒ1, ｄｄｒ2 또는 ｐｄｇｆ-ｒ 키나제 활성에 의해 매개된 증식성 장애 및 다른 병적 상태의 치료 방법
JO3634B1 (ar) 2009-11-17 2020-08-27 Novartis Ag طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r
IN2011CH01887A (fr) * 2011-06-02 2012-12-14
AR086913A1 (es) * 2011-06-14 2014-01-29 Novartis Ag 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas
CN102321073A (zh) * 2011-08-12 2012-01-18 西安交通大学 一种尼罗替尼的制备方法
JP2014532647A (ja) 2011-10-28 2014-12-08 ノバルティス アーゲー 消化管間質腫瘍を治療する方法
WO2013063003A1 (fr) 2011-10-28 2013-05-02 Novartis Ag Méthode de traitement des tumeurs stromales gastro-intestinales
US9301957B2 (en) 2011-11-14 2016-04-05 Novartis Ag Immediate release 4-methyl-3-4[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-YL)-3-(trifluoromethyl)phenyl] benzamide formulation
IN2014DN03416A (fr) * 2011-11-14 2015-06-26 Novartis Ag
WO2014011284A1 (fr) 2012-07-11 2014-01-16 Novartis Ag Méthode de traitement de tumeurs stromales gastro-intestinales
WO2014174496A1 (fr) 2013-04-25 2014-10-30 Ranbaxy Laboratories Limited Forme posologique orale solide de produit pharmaceutique à rétention gastrique de nilotinib
US9636340B2 (en) 2013-11-12 2017-05-02 Ayyappan K. Rajasekaran Kinase inhibitors
LT3189045T (lt) * 2014-08-11 2022-04-11 Sun Pharmaceutical Industries Limited Naujos nilotinibo druskos ir jų polimorfai
US10045987B2 (en) * 2014-08-28 2018-08-14 Codexis, Inc. Imidazoyl anilide derivatives and methods of use
BR112018068784A2 (pt) * 2016-03-17 2019-01-22 Sun Pharmaceutical Ind Ltd método para o tratamento de leucemia
CN107582531B (zh) * 2016-07-06 2020-12-29 四川科伦药物研究院有限公司 一种利伐沙班固体制剂及其制备方法
CN107320460B (zh) * 2017-08-04 2020-11-03 北京化工大学 一种尼罗替尼口服纳米制剂及其制备方法
CN107441094B (zh) * 2017-08-08 2020-05-22 南方医科大学 尼罗替尼作为治疗登革病毒感染的药物及其制药用途
CZ2017821A3 (cs) 2017-12-20 2019-07-03 Zentiva, K.S. Léková forma obsahující krystalický nilotinib
TWI787523B (zh) 2018-06-15 2022-12-21 漢達生技醫藥股份有限公司 達沙替尼十二烷基硫酸鹽之結晶
IL295007A (en) 2020-01-31 2022-09-01 Nanocopoeia Llc Amorphous nilotinib microparticles and uses thereof
WO2021222739A1 (fr) 2020-04-30 2021-11-04 Nanocopoeia, Llc Comprimé à désintégration orale comprenant une dispersion solide amorphe de nilotinib
JP7489849B2 (ja) * 2020-07-20 2024-05-24 日本化薬株式会社 ニロチニブ錠剤
MX2023003556A (es) 2020-09-29 2023-06-13 Shenzhen Pharmacin Co Ltd Composiciones farmaceuticas.
AU2022292092A1 (en) 2021-06-19 2024-02-01 Helm Pharmaceuticals Gmbh Granulate composition comprising nilotinib
WO2023285981A1 (fr) * 2021-07-15 2023-01-19 Torrent Pharmaceuticals Limited Composition pharmaceutique liquide stable de nilotinib
EP4122452A1 (fr) 2021-07-23 2023-01-25 KRKA, d.d., Novo mesto Composition pharmaceutique comprenant du nilotinib et son procédé de fabrication
EP4260848A1 (fr) 2022-04-11 2023-10-18 Lotus Pharmaceutical Co., Ltd. Composition pharmaceutique pour forme posologique solide contenant du nilotinib et son procédé de préparation
LU103368B1 (en) 2022-12-29 2024-11-04 Renata Pharmaceuticals Ireland Ltd Pharmaceutical suspension of nilotinib
WO2024194718A1 (fr) * 2023-03-22 2024-09-26 Unichem Laboratories Limited Composition pharmaceutique stable et son procédé de préparation

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GT200600316A (es) 2005-07-20 2007-04-02 Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
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EP1923053A1 (fr) 2006-09-27 2008-05-21 Novartis AG Composition pharmaceutique comprenant de la nilotinib ou son sel

Also Published As

Publication number Publication date
TWI428333B (zh) 2014-03-01
US20130023549A1 (en) 2013-01-24
KR101598747B1 (ko) 2016-03-02
IL197496A (en) 2016-04-21
KR20090076931A (ko) 2009-07-13
WO2008037716A2 (fr) 2008-04-03
EP1923053A1 (fr) 2008-05-21
AR062980A1 (es) 2008-12-17
EP3984528A1 (fr) 2022-04-20
JP5567340B2 (ja) 2014-08-06
KR20140121903A (ko) 2014-10-16
AU2007301977B2 (en) 2011-09-08
HUE028204T2 (en) 2016-12-28
HRP20151383T4 (hr) 2023-03-03
CN104306350A (zh) 2015-01-28
EP2068839B2 (fr) 2022-10-12
PE20120626A1 (es) 2012-06-07
RU2009115782A (ru) 2010-11-10
TW201418245A (zh) 2014-05-16
WO2008037716A3 (fr) 2008-07-17
BRPI0719438B1 (pt) 2022-04-19
HK1133193A1 (en) 2010-03-19
CY1126116T1 (el) 2023-11-15
CO6160288A2 (es) 2010-05-20
PT3984528T (pt) 2023-08-07
DK2068839T3 (da) 2016-01-11
DK3984528T3 (da) 2023-07-31
ES2556625T5 (es) 2023-03-02
NO347404B1 (no) 2023-10-16
HRP20151383T1 (hr) 2016-01-15
ZA200901511B (en) 2010-02-24
MY148237A (en) 2013-03-29
EP2068839A2 (fr) 2009-06-17
CY1117021T1 (el) 2017-04-05
AU2007301977A1 (en) 2008-04-03
CN101516344A (zh) 2009-08-26
EP3984528B1 (fr) 2023-07-05
PL2068839T5 (pl) 2023-01-30
TN2009000093A1 (en) 2010-08-19
JP2014065715A (ja) 2014-04-17
NO20220946A1 (no) 2009-04-24
PE20081379A1 (es) 2008-11-27
HRP20230753T3 (hr) 2023-10-27
EP3009128B1 (fr) 2023-07-05
SI2068839T2 (sl) 2023-01-31
US8501760B2 (en) 2013-08-06
JO3757B1 (ar) 2021-01-31
ES2556625T3 (es) 2016-01-19
FI2068839T4 (fi) 2023-01-31
RU2469707C2 (ru) 2012-12-20
BRPI0719438A2 (pt) 2013-12-10
IL197496A0 (en) 2009-12-24
SI3984528T1 (sl) 2023-09-29
ES2957912T3 (es) 2024-01-29
PL2068839T3 (pl) 2016-06-30
CL2007002766A1 (es) 2008-08-08
CA2662571A1 (fr) 2008-04-03
CA2662571C (fr) 2016-09-27
NZ575317A (en) 2011-12-22
EP2068839B1 (fr) 2015-09-23
LT3984528T (lt) 2023-08-10
FI3984528T3 (fi) 2023-07-27
MX2009003184A (es) 2009-04-03
TWI540128B (zh) 2016-07-01
JP2010504942A (ja) 2010-02-18
TW201418244A (zh) 2014-05-16
HUE063083T2 (hu) 2023-12-28
NO346639B1 (no) 2022-11-07
US20100087463A1 (en) 2010-04-08
NO20091501L (no) 2009-04-24
EP3009128A1 (fr) 2016-04-20
SI2068839T1 (sl) 2016-02-29
ES2951547T3 (es) 2023-10-23
PL3984528T3 (pl) 2023-08-28
TW200821298A (en) 2008-05-16
US8293756B2 (en) 2012-10-23
PT2068839E (pt) 2015-12-30

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