ZA978204B - Monoclonal antibodies against the extracellular domain of human VEGF-receptor protein (KDR) - Google Patents
Monoclonal antibodies against the extracellular domain of human VEGF-receptor protein (KDR)Info
- Publication number
- ZA978204B ZA978204B ZA9708204A ZA978204A ZA978204B ZA 978204 B ZA978204 B ZA 978204B ZA 9708204 A ZA9708204 A ZA 9708204A ZA 978204 A ZA978204 A ZA 978204A ZA 978204 B ZA978204 B ZA 978204B
- Authority
- ZA
- South Africa
- Prior art keywords
- kdr
- monoclonal antibodies
- extracellular domain
- antibodies against
- receptor protein
- Prior art date
Links
- 108091008605 VEGF receptors Proteins 0.000 title 1
- 102000009484 Vascular Endothelial Growth Factor Receptors Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
- A61K51/103—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants against receptors for growth factors or receptors for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19638745A DE19638745C2 (de) | 1996-09-11 | 1996-09-11 | Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA978204B true ZA978204B (en) | 1998-03-03 |
Family
ID=7806450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9708204A ZA978204B (en) | 1996-09-11 | 1997-09-11 | Monoclonal antibodies against the extracellular domain of human VEGF-receptor protein (KDR) |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6344339B1 (xx) |
| EP (1) | EP0925359A1 (xx) |
| JP (1) | JP2001501920A (xx) |
| AU (1) | AU730287B2 (xx) |
| CA (1) | CA2265927A1 (xx) |
| DE (1) | DE19638745C2 (xx) |
| HU (1) | HUP9904052A3 (xx) |
| IL (1) | IL128406A0 (xx) |
| NO (1) | NO991162L (xx) |
| PL (1) | PL332034A1 (xx) |
| WO (1) | WO1998011223A1 (xx) |
| ZA (1) | ZA978204B (xx) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2299099A (en) * | 1998-02-04 | 1999-08-23 | Kyowa Hakko Kogyo Co. Ltd. | Antibodies against human vegf receptor kdr |
| DE19813774A1 (de) * | 1998-03-27 | 1999-09-30 | Max Planck Gesellschaft | Parapockenvirus-kodierter vaskulärer Endothelzell Wachstumsfaktor (PPV-VEGF) |
| NO983911D0 (no) * | 1998-08-26 | 1998-08-26 | Norsk Hydro As | Alginatkapsler til bruk ved behandling av hjernesvulst |
| BR9915139A (pt) * | 1998-11-06 | 2001-08-07 | Basf Ag | Método de inibir a hiperpermeabilidade vascular, e de inibir um processo ou estado fisiológico em um indivìduo |
| AU3475100A (en) * | 1999-01-29 | 2000-08-18 | Imclone Systems Incorporated | Antibodies specific to kdr and uses thereof |
| EP1130032A1 (en) * | 2000-02-28 | 2001-09-05 | Gesellschaft für biotechnologische Forschung mbH (GBF) | Single-chain antibodies recognizing the human vascular endothelial growth factor receptor-2 (VEGFR-2/KDR) |
| CN104083365A (zh) | 2001-02-19 | 2014-10-08 | 诺华股份有限公司 | 癌症的治疗 |
| US20040167134A1 (en) | 2001-05-16 | 2004-08-26 | Christian Bruns | Combination comprising n-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent |
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| US7250289B2 (en) * | 2002-11-20 | 2007-07-31 | Affymetrix, Inc. | Methods of genetic analysis of mouse |
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Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1173991C (zh) * | 1992-11-13 | 2004-11-03 | 马克斯普朗克科学促进协会 | 作为血管内皮生长因子受体的f1k-1 |
| US5840301A (en) * | 1994-02-10 | 1998-11-24 | Imclone Systems Incorporated | Methods of use of chimerized, humanized, and single chain antibodies specific to VEGF receptors |
| US5861499A (en) * | 1994-02-10 | 1999-01-19 | Imclone Systems Incorporated | Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain |
-
1996
- 1996-09-11 DE DE19638745A patent/DE19638745C2/de not_active Expired - Fee Related
-
1997
- 1997-09-09 AU AU46222/97A patent/AU730287B2/en not_active Ceased
- 1997-09-09 IL IL12840697A patent/IL128406A0/xx unknown
- 1997-09-09 JP JP10513245A patent/JP2001501920A/ja not_active Ceased
- 1997-09-09 HU HU9904052A patent/HUP9904052A3/hu unknown
- 1997-09-09 EP EP97944862A patent/EP0925359A1/en not_active Withdrawn
- 1997-09-09 WO PCT/EP1997/004928 patent/WO1998011223A1/en not_active Ceased
- 1997-09-09 PL PL97332034A patent/PL332034A1/xx unknown
- 1997-09-09 US US09/254,640 patent/US6344339B1/en not_active Expired - Fee Related
- 1997-09-09 CA CA002265927A patent/CA2265927A1/en not_active Abandoned
- 1997-09-11 ZA ZA9708204A patent/ZA978204B/xx unknown
-
1999
- 1999-03-10 NO NO991162A patent/NO991162L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US6344339B1 (en) | 2002-02-05 |
| EP0925359A1 (en) | 1999-06-30 |
| NO991162D0 (no) | 1999-03-10 |
| DE19638745C2 (de) | 2001-05-10 |
| JP2001501920A (ja) | 2001-02-13 |
| HUP9904052A2 (hu) | 2000-03-28 |
| CA2265927A1 (en) | 1998-03-19 |
| WO1998011223A1 (en) | 1998-03-19 |
| IL128406A0 (en) | 2000-01-31 |
| AU4622297A (en) | 1998-04-02 |
| HUP9904052A3 (en) | 2002-01-28 |
| AU730287B2 (en) | 2001-03-01 |
| NO991162L (no) | 1999-05-06 |
| PL332034A1 (en) | 1999-08-16 |
| DE19638745A1 (de) | 1998-03-12 |
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