ZA977969B - Reflux inhibitors. - Google Patents

Reflux inhibitors.

Info

Publication number: ZA977969B
Authority: ZA; South Africa
Prior art keywords: reflux inhibitors; reflux; inhibitors
Prior art date: 1996-09-18

Application number

ZA9707969A

Other languages

English (en)

Inventor

Paul Andrews

Anders Lehmann

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-18

Filing date

1997-09-04

Publication date

1998-03-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20403936&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA977969(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-09-04 Application filed by Astra Ab filed Critical Astra Ab

1998-03-18 Publication of ZA977969B publication Critical patent/ZA977969B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
- G01N33/9426—GABA, i.e. gamma-amino-butyrate
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Cell Biology (AREA)
General Physics & Mathematics (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Pathology (AREA)
Food Science & Technology (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Otolaryngology (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

ZA9707969A 1996-09-18 1997-09-04 Reflux inhibitors. ZA977969B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9603408A SE9603408D0 (sv)	1996-09-18	1996-09-18	Medical use

Publications (1)

Publication Number	Publication Date
ZA977969B true ZA977969B (en)	1998-03-18

Family

ID=20403936

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9707969A ZA977969B (en)	1996-09-18	1997-09-04	Reflux inhibitors.

Country Status (34)

Country	Link
US (2)	US6117908A (xx)
EP (2)	EP0936906B1 (xx)
JP (1)	JP4098832B2 (xx)
KR (2)	KR100553294B1 (xx)
CN (1)	CN1117560C (xx)
AR (1)	AR007747A1 (xx)
AT (2)	ATE249212T1 (xx)
AU (1)	AU714370B2 (xx)
BR (1)	BR9711400A (xx)
CA (1)	CA2265615C (xx)
CZ (1)	CZ299997B6 (xx)
DE (2)	DE69724809T2 (xx)
DK (2)	DK1344524T3 (xx)
EE (1)	EE03952B1 (xx)
ES (2)	ES2268227T3 (xx)
HU (1)	HU224968B1 (xx)
ID (1)	ID19621A (xx)
IL (1)	IL128961A (xx)
IS (2)	IS2329B (xx)
MY (1)	MY122020A (xx)
NO (1)	NO326837B1 (xx)
NZ (2)	NZ504244A (xx)
PL (1)	PL190028B1 (xx)
PT (2)	PT1344524E (xx)
RU (1)	RU2199316C2 (xx)
SA (1)	SA97180522B1 (xx)
SE (1)	SE9603408D0 (xx)
SI (2)	SI0936906T1 (xx)
SK (1)	SK285744B6 (xx)
TR (1)	TR199900591T2 (xx)
TW (1)	TW548104B (xx)
UA (1)	UA61081C2 (xx)
WO (1)	WO1998011885A1 (xx)
ZA (1)	ZA977969B (xx)

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SE9904507D0 (sv) *	1999-12-09	1999-12-09	Astra Ab	New compounds
SE9904508D0 (sv)	1999-12-09	1999-12-09	Astra Ab	New compounds
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AR033779A1 (es)	2001-06-08	2004-01-07	Astrazeneca Ab	Compuestos utiles en la enfermedad de reflujo
SE0102055D0 (sv) *	2001-06-08	2001-06-08	Astrazeneca Ab	New Compounds
SE0102058D0 (sv) *	2001-06-08	2001-06-08	Astrazeneca Ab	New Salts II
SE0102057D0 (sv) *	2001-06-08	2001-06-08	Astrazeneca Ab	New Salts I
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US7964609B2 (en)	2002-06-20	2011-06-21	Astrazeneca Ab	Use of mGluR5 antagonists for the treatment of gerd
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US8007827B2 (en) *	2004-04-02	2011-08-30	Impax Laboratories, Inc.	Pharmaceutical dosage forms having immediate release and/or controlled release properties
US20050220863A1 (en) *	2004-04-02	2005-10-06	Chien-Hsuan Han	Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist
US20050220873A1 (en) *	2004-04-02	2005-10-06	Chien-Hsuan Han	Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
SE0401653D0 (sv)	2004-06-24	2004-06-24	Astrazeneca Ab	New compounds
US7494985B2 (en) *	2004-11-03	2009-02-24	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
US7566738B2 (en) *	2004-11-03	2009-07-28	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2006071186A1 (en) *	2004-12-27	2006-07-06	Astrazeneca Ab	Use of gabab receptor agonists
WO2007073298A1 (en) *	2005-12-23	2007-06-28	Astrazeneca Ab	Imidazole derivatives for the treatment of gastrointestinal disorders
CA2632011A1 (en) *	2005-12-23	2007-06-28	Astrazeneca Ab	Pyrazoles for the treatment of gerd and ibs
EP1966176A4 (en) *	2005-12-23	2011-08-10	Astrazeneca Ab	HETEROCYCLIC GABA B MODULATORS
JP2009521430A (ja)	2005-12-23	2009-06-04	アストラゼネカ・アクチエボラーグ	Ｇａｂａ−ｂ受容体モジュレーター
JP2009521429A (ja) *	2005-12-23	2009-06-04	アストラゼネカ・アクチエボラーグ	Ｇａｂａ−ｂ受容体モジュレーターとしてのイミダゾール
WO2008033572A1 (en) *	2006-09-15	2008-03-20	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
NZ598728A (en) *	2006-12-22	2013-09-27	Ironwood Pharmaceuticals Inc	Compositions comprising bile acid sequestrants for treating esophageal disorders
ATE511392T1 (de) *	2007-01-11	2011-06-15	Xenoport Inc	Verzögert freigesetzte orale dosierungsformen eines prodrugs von r-baclofen und behandlungsverfahren damit
KR20100015648A (ko) *	2007-04-18	2010-02-12	아스트라제네카 아베	양성 알로스테릭 ｇａｂａｂ 수용체 조절제 효과를 갖는 크산틴 화합물
TW200908957A (en) *	2007-06-15	2009-03-01	Xenoport Inc	Use of prodrugs of GABA analogs, antispasticity agents, and prodrugs of GABAB receptor agonists for treating spasticity
WO2009014491A1 (en) *	2007-07-25	2009-01-29	Astrazeneca Ab	The use of (3-amino-2-fluoropropyl) phosphinic acid for treatment of nerd
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US7868043B2 (en)	2008-01-25	2011-01-11	Xenoport, Inc.	Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
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WO2009117160A2 (en) *	2008-03-20	2009-09-24	General Mills, Inc.	Compound and method for treatment of gastroesophageal reflux
US8299291B2 (en) *	2008-08-07	2012-10-30	Xenoport, Inc.	Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
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CN102341099A (zh)	2009-03-03	2012-02-01	什诺波特有限公司	R-巴氯芬前药的持续释放口服剂型
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1996
- 1996-09-18 SE SE9603408A patent/SE9603408D0/xx unknown
1997
- 1997-09-04 ZA ZA9707969A patent/ZA977969B/xx unknown
- 1997-09-04 AR ARP970104051A patent/AR007747A1/es unknown
- 1997-09-12 TW TW086113275A patent/TW548104B/zh not_active IP Right Cessation
- 1997-09-12 ID IDP973172A patent/ID19621A/id unknown
- 1997-09-15 SI SI9730594T patent/SI0936906T1/xx unknown
- 1997-09-15 ES ES03013667T patent/ES2268227T3/es not_active Expired - Lifetime
- 1997-09-15 UA UA99031298A patent/UA61081C2/uk unknown
- 1997-09-15 PL PL97332497A patent/PL190028B1/pl not_active IP Right Cessation
- 1997-09-15 IL IL12896197A patent/IL128961A/en not_active IP Right Cessation
- 1997-09-15 CN CN97199600A patent/CN1117560C/zh not_active Expired - Fee Related
- 1997-09-15 BR BR9711400A patent/BR9711400A/pt not_active Application Discontinuation
- 1997-09-15 CZ CZ0093099A patent/CZ299997B6/cs not_active IP Right Cessation
- 1997-09-15 AT AT97942346T patent/ATE249212T1/de active
- 1997-09-15 SI SI9730749T patent/SI1344524T1/sl unknown
- 1997-09-15 EE EEP199900095A patent/EE03952B1/xx not_active IP Right Cessation
- 1997-09-15 NZ NZ504244A patent/NZ504244A/xx not_active IP Right Cessation
- 1997-09-15 NZ NZ334495A patent/NZ334495A/xx not_active IP Right Cessation
- 1997-09-15 ES ES97942346T patent/ES2206749T3/es not_active Expired - Lifetime
- 1997-09-15 KR KR1019997002239A patent/KR100553294B1/ko not_active Expired - Fee Related
- 1997-09-15 HU HU9903825A patent/HU224968B1/hu not_active IP Right Cessation
- 1997-09-15 DE DE69724809T patent/DE69724809T2/de not_active Expired - Lifetime
- 1997-09-15 DK DK03013667T patent/DK1344524T3/da active
- 1997-09-15 EP EP97942346A patent/EP0936906B1/en not_active Expired - Lifetime
- 1997-09-15 DE DE69736445T patent/DE69736445T2/de not_active Expired - Lifetime
- 1997-09-15 PT PT03013667T patent/PT1344524E/pt unknown
- 1997-09-15 RU RU99107969/14A patent/RU2199316C2/ru not_active IP Right Cessation
- 1997-09-15 AT AT03013667T patent/ATE334700T1/de active
- 1997-09-15 WO PCT/SE1997/001555 patent/WO1998011885A1/en not_active Ceased
- 1997-09-15 EP EP03013667A patent/EP1344524B1/en not_active Expired - Lifetime
- 1997-09-15 PT PT97942346T patent/PT936906E/pt unknown
- 1997-09-15 JP JP51458198A patent/JP4098832B2/ja not_active Expired - Fee Related
- 1997-09-15 AU AU44064/97A patent/AU714370B2/en not_active Ceased
- 1997-09-15 DK DK97942346T patent/DK0936906T3/da active
- 1997-09-15 KR KR1020057018539A patent/KR100568659B1/ko not_active Expired - Fee Related
- 1997-09-15 CA CA002265615A patent/CA2265615C/en not_active Expired - Fee Related
- 1997-09-15 TR TR1999/00591T patent/TR199900591T2/xx unknown
- 1997-09-15 SK SK305-99A patent/SK285744B6/sk not_active IP Right Cessation
- 1997-09-15 US US08/952,400 patent/US6117908A/en not_active Expired - Lifetime
- 1997-09-16 MY MYPI97004296A patent/MY122020A/en unknown
- 1997-10-27 SA SA97180522A patent/SA97180522B1/ar unknown
1999
- 1999-03-15 IS IS5001A patent/IS2329B/is unknown
- 1999-03-17 NO NO19991287A patent/NO326837B1/no not_active IP Right Cessation
2000
- 2000-09-08 US US09/658,242 patent/US6664069B1/en not_active Expired - Fee Related
2007
- 2007-03-19 IS IS8623A patent/IS2538B/is unknown

Also Published As

Publication number	Publication date
SA97180522B1 (ar)	2006-04-04
KR20000036185A (ko)	2000-06-26
US6117908A (en)	2000-09-12
DE69724809T2 (de)	2004-07-15
AU714370B2 (en)	1999-12-23
HUP9903825A2 (hu)	2001-05-28
ATE249212T1 (de)	2003-09-15
KR100568659B1 (ko)	2006-04-07
SI1344524T1 (sl)	2006-12-31
NZ334495A (en)	2000-09-29
HU224968B1 (en)	2006-04-28
JP4098832B2 (ja)	2008-06-11
WO1998011885A1 (en)	1998-03-26
HUP9903825A3 (en)	2001-06-28
US6664069B1 (en)	2003-12-16
SI0936906T1 (en)	2004-02-29
EP0936906B1 (en)	2003-09-10
CA2265615A1 (en)	1998-03-26
TW548104B (en)	2003-08-21
DE69724809D1 (de)	2003-10-16
IS8623A (is)	2007-03-19
IS2538B (is)	2009-09-15
NZ504244A (en)	2000-09-29
ID19621A (id)	1998-07-23
BR9711400A (pt)	1999-08-17
SE9603408D0 (sv)	1996-09-18
TR199900591T2 (xx)	1999-07-21
KR100553294B1 (ko)	2006-02-22
CA2265615C (en)	2007-01-30
ES2206749T3 (es)	2004-05-16
IL128961A (en)	2004-08-31
PL332497A1 (en)	1999-09-13
NO991287D0 (no)	1999-03-17
PT936906E (pt)	2003-12-31
EP1344524B1 (en)	2006-08-02
JP2001501604A (ja)	2001-02-06
SK285744B6 (sk)	2007-07-06
IL128961A0 (en)	2000-02-17
ES2268227T3 (es)	2007-03-16
UA61081C2 (uk)	2003-11-17
CN1117560C (zh)	2003-08-13
IS5001A (is)	1999-03-15
CZ93099A3 (cs)	1999-09-15
HK1057004A1 (en)	2004-03-12
NO326837B1 (no)	2009-02-23
IS2329B (is)	2008-01-15
NO991287L (no)	1999-03-17
CZ299997B6 (cs)	2009-01-14
DK0936906T3 (da)	2003-11-24
CN1237105A (zh)	1999-12-01
EE03952B1 (et)	2003-02-17
DK1344524T3 (da)	2006-10-30
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PT1344524E (pt)	2006-11-30
AR007747A1 (es)	1999-11-10
AU4406497A (en)	1998-04-14
DE69736445T2 (de)	2007-03-15
MY122020A (en)	2006-03-31
HK1022100A1 (en)	2000-07-28
ATE334700T1 (de)	2006-08-15
DE69736445D1 (de)	2006-09-14
RU2199316C2 (ru)	2003-02-27
EP1344524A1 (en)	2003-09-17
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PL190028B1 (pl)	2005-10-31
SK30599A3 (en)	2000-01-18

Publication	Publication Date	Title
ZA977969B (en)	1998-03-18	Reflux inhibitors.
PL331338A1 (en)	1999-07-05	Thiosulphonamidic metaloprotease inhibitors
ZA977086B (en)	1998-06-30	NAALADase inhibitors.
ZA98376B (en)	1998-07-23	Sulfamide-metalloprotease inhibitors
IL128663A0 (en)	2000-01-31	1,4-heterocyclic metalloprotease inhibitors
IL128661A0 (en)	2000-01-31	1,3-diheterocyclic metalloprotease inhibitors
ZA979985B (en)	1998-05-07	N-substituted 2-cyanopyrrolidines.
GB2321641B (en)	2001-04-04	Sulfamide-metalloprotease inhibitors
ZA9710429B (en)	1998-06-10	Broad-spectrumδ-endotoxins.
ZA979199B (en)	1998-05-11	Aminothiophenecarboxamides.
ZA9811794B (en)	1999-06-29	Ace inhibitor-MMP inhibitor combinations.
ZA978304B (en)	1998-03-24	3-alkyl-3-phenyl-piperidines.
PL331803A1 (en)	1999-08-02	Bidonoric metaloprotease inhibitors
ZA97572B (en)	1997-08-04	1-pyrazol-3-ylethyl-4-indol-3-ylpiperidines.
ZA974779B (en)	1997-12-01	Thrombin inhibitors.
ZA977209B (en)	1998-02-20	Thrombin inhibitors.
ZA974052B (en)	1998-01-14	New benzothiazolinones.
ZA9710860B (en)	1998-06-08	Adhesives.
ZA976022B (en)	1998-02-02	Cycloalkano-pyridines.
ZA971466B (en)	1997-08-28	Endothelin-receptor-antagonists.
ZA992106B (en)	1999-09-30	Statin-MMP inhibitor combinations.
ZA974056B (en)	1998-01-14	New thiazolopyridines.
ZA971474B (en)	1997-08-28	Endothelin-receptor-antagonists.
ZA975469B (en)	1997-12-22	X14-mannitol.
GB9623742D0 (en)	1997-01-08	Inhibitors