ZA9511035B - 8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application - Google Patents

8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application

Info

Publication number: ZA9511035B
Authority: ZA; South Africa
Prior art keywords: quinolizine; dibenzo; dihydro; oxo; preparation
Prior art date: 1994-12-29

Application number

ZA9511035A

Other languages

English (en)

Inventor

Benoit Marabout

Mireille Sevrin

Jacques Froissant

Emmanuelle Dachary

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-29

Filing date

1995-12-28

Publication date

1996-07-01

1995-12-28 Application filed by Synthelabo filed Critical Synthelabo

1996-07-01 Publication of ZA9511035B publication Critical patent/ZA9511035B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Diabetes (AREA)
Addiction (AREA)
Endocrinology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

ZA9511035A 1994-12-29 1995-12-28 8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application ZA9511035B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9415836A FR2728902B1 (fr)	1994-12-29	1994-12-29	Derives d'acide 8-oxo-5,8-dihydro-6h-dibenzo(a,g)quinolizine-13-propanoique, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
ZA9511035B true ZA9511035B (en)	1996-07-01

Family

ID=9470389

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9511035A ZA9511035B (en)	1994-12-29	1995-12-28	8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application

Country Status (26)

Country	Link
US (1)	US5614517A (es)
EP (1)	EP0719776B1 (es)
JP (1)	JPH08239383A (es)
KR (1)	KR960022518A (es)
CN (1)	CN1058009C (es)
AR (1)	AR002015A1 (es)
AT (1)	ATE172973T1 (es)
AU (1)	AU697988B2 (es)
BR (1)	BR9506105A (es)
CA (1)	CA2166233A1 (es)
CO (1)	CO4700297A1 (es)
CZ (1)	CZ348895A3 (es)
DE (1)	DE69505781T2 (es)
DK (1)	DK0719776T3 (es)
ES (1)	ES2126232T3 (es)
FI (1)	FI956299L (es)
FR (1)	FR2728902B1 (es)
HU (1)	HU215393B (es)
IL (1)	IL116596A (es)
NO (1)	NO305084B1 (es)
NZ (1)	NZ280766A (es)
PL (1)	PL181811B1 (es)
RU (1)	RU2155764C2 (es)
SK (1)	SK280546B6 (es)
TW (1)	TW385311B (es)
ZA (1)	ZA9511035B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2806723B1 (fr) *	2000-03-23	2002-05-10	Sanofi Synthelabo	DERIVES D'ACIDE 8-OXO-5,8-DIHYDRO-6H-DIBENZO [a,g] QUINOLIZINE-13-PROPANOIQUE , LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US6686352B2 (en) *	2001-05-18	2004-02-03	Hoffmann-La Roche Inc.	Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives
CN104127414B (zh) *	2013-05-03	2018-04-13	中国科学院上海药物研究所	一种六氢二苯并[a,g]喹嗪类化合物的药物用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4013616A (en) *	1971-11-22	1977-03-22	Wallace Richard A	Mixed polymeric structural material and method
FR2537583B1 (fr) *	1982-12-14	1985-08-09	Urpha	Enantiomeres levogyres des derives de la tetrahydro-5, 6, 13, 13a 8h-dibenzo (a,g-) quinolizine, procedes d'obtention, compositions pharmaceutiques les contenant et application
GB8429710D0 (en) *	1984-11-23	1985-01-03	Fujisawa Pharmaceutical Co	Pharmaceutical composition
JPS61130289A (ja) *	1984-11-29	1986-06-18	Ss Pharmaceut Co Ltd	１３−プロピルベルベリンの塩
HU195505B (en) *	1985-05-24	1988-05-30	Chinoin Gyogyszer Es Vegyeszet	Process for producing 7,8-methylendioxy-14-hydroxy-berban derivatives and pharmaceuticals comprising the same

1994
- 1994-12-29 FR FR9415836A patent/FR2728902B1/fr not_active Expired - Fee Related
1995
- 1995-12-18 DK DK95402841T patent/DK0719776T3/da active
- 1995-12-18 AT AT95402841T patent/ATE172973T1/de not_active IP Right Cessation
- 1995-12-18 ES ES95402841T patent/ES2126232T3/es not_active Expired - Lifetime
- 1995-12-18 EP EP95402841A patent/EP0719776B1/fr not_active Expired - Lifetime
- 1995-12-18 DE DE69505781T patent/DE69505781T2/de not_active Expired - Fee Related
- 1995-12-21 NZ NZ280766A patent/NZ280766A/en unknown
- 1995-12-27 AR ARP950100766A patent/AR002015A1/es unknown
- 1995-12-27 TW TW084113949A patent/TW385311B/zh not_active IP Right Cessation
- 1995-12-28 AU AU40708/95A patent/AU697988B2/en not_active Ceased
- 1995-12-28 RU RU95122601/04A patent/RU2155764C2/ru active
- 1995-12-28 SK SK1658-95A patent/SK280546B6/sk unknown
- 1995-12-28 PL PL95312080A patent/PL181811B1/pl unknown
- 1995-12-28 JP JP7342620A patent/JPH08239383A/ja not_active Withdrawn
- 1995-12-28 KR KR1019950061342A patent/KR960022518A/ko not_active Ceased
- 1995-12-28 CN CN95120636A patent/CN1058009C/zh not_active Expired - Fee Related
- 1995-12-28 NO NO955325A patent/NO305084B1/no not_active IP Right Cessation
- 1995-12-28 US US08/580,295 patent/US5614517A/en not_active Expired - Fee Related
- 1995-12-28 ZA ZA9511035A patent/ZA9511035B/xx unknown
- 1995-12-28 FI FI956299A patent/FI956299L/fi unknown
- 1995-12-28 IL IL11659695A patent/IL116596A/en not_active IP Right Cessation
- 1995-12-28 CA CA002166233A patent/CA2166233A1/en not_active Abandoned
- 1995-12-28 BR BR9506105A patent/BR9506105A/pt not_active Application Discontinuation
- 1995-12-28 CZ CZ953488A patent/CZ348895A3/cs unknown
- 1995-12-28 HU HU9503846A patent/HU215393B/hu not_active IP Right Cessation
- 1995-12-28 CO CO95062143A patent/CO4700297A1/es unknown

Also Published As

Publication number	Publication date
ATE172973T1 (de)	1998-11-15
RU2155764C2 (ru)	2000-09-10
KR960022518A (ko)	1996-07-18
HUT74186A (en)	1996-11-28
DE69505781T2 (de)	1999-06-17
EP0719776A1 (fr)	1996-07-03
DE69505781D1 (de)	1998-12-10
PL312080A1 (en)	1996-07-08
NO955325L (no)	1996-07-01
HU215393B (hu)	1998-12-28
IL116596A0 (en)	1996-03-31
HU9503846D0 (en)	1996-02-28
AU4070895A (en)	1996-07-04
SK280546B6 (sk)	2000-03-13
CN1131154A (zh)	1996-09-18
CA2166233A1 (en)	1996-06-30
AR002015A1 (es)	1998-01-07
NO955325D0 (no)	1995-12-28
IL116596A (en)	1998-10-30
FI956299A7 (fi)	1996-06-30
TW385311B (en)	2000-03-21
CO4700297A1 (es)	1998-12-29
NO305084B1 (no)	1999-03-29
CZ348895A3 (en)	1996-07-17
US5614517A (en)	1997-03-25
BR9506105A (pt)	1997-12-23
ES2126232T3 (es)	1999-03-16
CN1058009C (zh)	2000-11-01
FI956299L (fi)	1996-06-30
NZ280766A (en)	1996-09-25
DK0719776T3 (da)	1999-07-19
FR2728902B1 (fr)	1997-01-31
EP0719776B1 (fr)	1998-11-04
FR2728902A1 (fr)	1996-07-05
FI956299A0 (fi)	1995-12-28
PL181811B1 (pl)	2001-09-28
AU697988B2 (en)	1998-10-22
SK165895A3 (en)	1996-07-03
JPH08239383A (ja)	1996-09-17

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AU1475595A (en)	1995-09-21	Pharmaceutical preparation
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GR3034797T3 (en)	2001-02-28	Carboxylic acid derivatives, their preparation and their use
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