ZA93141B - Piperazine derivatives - Google Patents
Piperazine derivativesInfo
- Publication number
- ZA93141B ZA93141B ZA93141A ZA93141A ZA93141B ZA 93141 B ZA93141 B ZA 93141B ZA 93141 A ZA93141 A ZA 93141A ZA 93141 A ZA93141 A ZA 93141A ZA 93141 B ZA93141 B ZA 93141B
- Authority
- ZA
- South Africa
- Prior art keywords
- pct
- date jul
- sec
- lower alkyl
- alkyl groups
- Prior art date
Links
- 150000004885 piperazines Chemical class 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 heteroaryl radical Chemical class 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000000049 anti-anxiety effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000004634 feeding behavior Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000036299 sexual function Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929200293A GB9200293D0 (en) | 1992-01-08 | 1992-01-08 | Piperazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA93141B true ZA93141B (en) | 1994-07-08 |
Family
ID=10708249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA93141A ZA93141B (en) | 1992-01-08 | 1993-01-08 | Piperazine derivatives |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5532242A (ja) |
| EP (1) | EP0620817B1 (ja) |
| JP (1) | JP3274865B2 (ja) |
| KR (1) | KR100283345B1 (ja) |
| AT (1) | ATE183504T1 (ja) |
| AU (1) | AU668901B2 (ja) |
| BR (1) | BR9207030A (ja) |
| CA (1) | CA2125182A1 (ja) |
| DE (1) | DE69229834T2 (ja) |
| ES (1) | ES2134835T3 (ja) |
| FI (1) | FI106200B (ja) |
| GB (2) | GB9200293D0 (ja) |
| HU (1) | HUT70513A (ja) |
| IL (1) | IL104305A (ja) |
| MX (1) | MX9300031A (ja) |
| NZ (1) | NZ246205A (ja) |
| PH (1) | PH30268A (ja) |
| RU (1) | RU2128653C1 (ja) |
| TW (1) | TW265337B (ja) |
| WO (1) | WO1993014076A1 (ja) |
| ZA (1) | ZA93141B (ja) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ314922A (en) * | 1992-12-21 | 1998-11-25 | Smithkline Beecham Corp | Benzodiazepinones; nitrogen containing heterocyclic intermediates and pharmaceutical compositions |
| US5609849A (en) * | 1994-03-11 | 1997-03-11 | The Trustees Of The University Of Pennsylvania | Serotonin (5-HT1A) receptor ligands and imaging agents |
| US5451584A (en) * | 1994-11-10 | 1995-09-19 | American Home Products Corporation | N-alkynyl carboxamides as sertonergic agents |
| US5541179A (en) * | 1995-05-02 | 1996-07-30 | American Home Products Corporation | Tropon-2-one piperazine carboxamides as serotonergic agents |
| CZ315098A3 (cs) * | 1996-04-05 | 1999-04-14 | Société De Conseils De Recherches Et D'applications Scientifiques (S. C. R. A. S.) | Antagonisté alfa1-adrenergických receptorů |
| US5610164A (en) * | 1996-07-24 | 1997-03-11 | American Home Products Corporation | (Thiophen-2-yl)-piperidin or tetrahydropyridin azabicyclocarboxamides |
| IT1293807B1 (it) * | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico |
| US6399614B1 (en) | 1997-08-01 | 2002-06-04 | Recordati S.A. Chemical And Pharmaceutical Company | 1-(N-phenylaminoalkyl)piperazine derivatives substituted at position 2 of the phenyl ring |
| IT1293804B1 (it) | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | Diarilalchilpiperazine attive sulle basse vie urinarie |
| RU2161614C2 (ru) * | 1998-03-17 | 2001-01-10 | Тульский государственный педагогический университет им. Л.Н. Толстого | Способ получения динатриевой соли n,n,-бис-(4-амино-2-сульфофенил)пиперазина |
| US6344458B1 (en) | 1998-12-17 | 2002-02-05 | American Home Products Corporation | Piperazine ethylamide derivatives |
| CA2351860A1 (en) * | 1998-12-17 | 2000-06-22 | Wyeth | Piperazine ethylamide derivatives with 5-ht1a receptor activity |
| WO2001068104A1 (en) | 2000-03-16 | 2001-09-20 | The Mclean Hospital Corporation | Compounds for the treatment of psychiatric or substance abuse disorders |
| AU6634201A (en) | 2000-06-27 | 2002-01-08 | Taisho Pharmaceutical Co Ltd | Remedial agent for anxiety neurosis or depression and piperazine derivative |
| AR034206A1 (es) * | 2001-02-16 | 2004-02-04 | Solvay Pharm Bv | Un procedimiento para la preparacion de mesilatos de derivados de piperazina y dichos mesilatos |
| US20040176316A1 (en) * | 2002-12-20 | 2004-09-09 | Renshaw Perry F. | Compounds for the normalization of the sleep/wake cycle |
| EP1765075A4 (en) | 2004-06-10 | 2010-11-10 | Mclean Hospital Corp | PYRIMIDINES, AS FORM. uridine; IN THE TREATMENT OF PATIENTS WITH MANIC-DEPRESSIVE PSYCHOSIS |
| EP1784199A4 (en) | 2004-08-11 | 2010-06-23 | Mclean Hospital Corp | COMPOUNDS FOR TREATING MARIHUANA DEPENDENCE, DEDUCTION AND CONSUMPTION |
| US7731940B2 (en) | 2006-01-25 | 2010-06-08 | The Regents Of The University Of California | Compositions and methods related to serotonin 5-HT1A receptors |
| TWI417095B (zh) | 2006-03-15 | 2013-12-01 | Janssen Pharmaceuticals Inc | 1,4-二取代之3-氰基-吡啶酮衍生物及其作為mGluR2-受體之正向異位性調節劑之用途 |
| TW200845978A (en) * | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| MY152078A (en) | 2007-09-14 | 2014-08-15 | Ortho Mcneil Janssen Pharm | 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h,1'h-[1,4']bipyridinyl-2'-ones |
| CA2697399C (en) | 2007-09-14 | 2016-01-19 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones |
| NZ584148A (en) * | 2007-09-14 | 2011-05-27 | Ortho Mcneil Janssen Pharm | 1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones |
| RU2492170C9 (ru) * | 2007-11-14 | 2013-12-27 | Орто-Макнейл-Янссен Фармасьютикалз, Инк. | Имидазо[1,2-а]пиридиновые производные и их применение в качестве положительных аллостерических модуляторов рецепторов mglur2 |
| AU2009289784B2 (en) | 2008-09-02 | 2012-03-22 | Addex Pharma S.A. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
| ES2466341T3 (es) | 2008-10-16 | 2014-06-10 | Janssen Pharmaceuticals, Inc. | Derivados de indol y benzomorfolina como moduladores de receptores de glutamato metabotrópicos |
| WO2010060589A1 (en) | 2008-11-28 | 2010-06-03 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
| NZ596053A (en) | 2009-05-12 | 2013-05-31 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| AU2010246609B2 (en) | 2009-05-12 | 2013-09-05 | Addex Pharma S.A. | 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| WO2011027656A1 (en) | 2009-09-04 | 2011-03-10 | Semiconductor Energy Laboratory Co., Ltd. | Transistor and display device |
| EP2661435B1 (en) | 2010-11-08 | 2015-08-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
| CN103298810B (zh) | 2010-11-08 | 2016-03-16 | 杨森制药公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
| EP2643320B1 (en) | 2010-11-08 | 2015-03-04 | Janssen Pharmaceuticals, Inc. | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
| CN103360342B (zh) * | 2012-04-09 | 2015-12-16 | 江苏恩华药业股份有限公司 | 3-氰基苯胺烷基芳基哌嗪衍生物及在制备药物中的应用 |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| DK3096790T3 (da) | 2014-01-21 | 2019-10-07 | Janssen Pharmaceutica Nv | Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse |
| KR20220038826A (ko) | 2014-01-21 | 2022-03-29 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3037982A (en) * | 1959-08-12 | 1962-06-05 | Miles Lab | Phenylpiperazinylalkyl propionanilides |
| SU534071A1 (ru) * | 1974-03-26 | 1980-04-30 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвийской Сср | -Замещенные пиперазины,обладающие психотропной активностью |
| AU532411B2 (en) * | 1979-03-01 | 1983-09-29 | Duphar International Research B.V. | Phenyl piperazine derivatives |
| NL8005133A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met antiagressieve werking. |
| NL8005131A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met analgetische werking. |
| EP0190472B1 (en) * | 1984-12-21 | 1989-07-12 | Duphar International Research B.V | New pharmaceutical compositions having anti-psychotic properties |
| US5010078A (en) * | 1988-05-24 | 1991-04-23 | American Home Products Corporation | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity |
| CA1340113C (en) * | 1988-05-24 | 1998-11-03 | Magid A. Abou-Gharbia | Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity |
| GB8909209D0 (en) * | 1989-04-22 | 1989-06-07 | Wyeth John & Brother Ltd | Piperazine derivatives |
| HUT54666A (en) * | 1989-04-22 | 1991-03-28 | Wyeth John & Brother Ltd | Process for producing peperazine derivatives and pharmaceutical compositions containing them |
| US5340812A (en) * | 1989-04-22 | 1994-08-23 | John Wyeth & Brother, Limited | Piperazine derivatives |
| IE64038B1 (en) * | 1989-04-22 | 1995-06-28 | Wyeth John & Brother Ltd | Tertiary alkyl functionalized piperazine derivatives |
| FR2655988B1 (fr) * | 1989-12-20 | 1994-05-20 | Adir Cie | Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| DK178590D0 (da) * | 1990-07-26 | 1990-07-26 | Novo Nordisk As | 1,4-disubstituerede piperaziner |
| ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
-
1992
- 1992-01-08 GB GB929200293A patent/GB9200293D0/en active Pending
- 1992-12-24 KR KR1019940702344A patent/KR100283345B1/ko not_active Expired - Fee Related
- 1992-12-24 AT AT93900365T patent/ATE183504T1/de not_active IP Right Cessation
- 1992-12-24 GB GB9227001A patent/GB2263110B/en not_active Expired - Fee Related
- 1992-12-24 ES ES93900365T patent/ES2134835T3/es not_active Expired - Lifetime
- 1992-12-24 RU RU94039542A patent/RU2128653C1/ru active
- 1992-12-24 CA CA002125182A patent/CA2125182A1/en not_active Abandoned
- 1992-12-24 US US08/256,330 patent/US5532242A/en not_active Expired - Lifetime
- 1992-12-24 JP JP51221993A patent/JP3274865B2/ja not_active Expired - Fee Related
- 1992-12-24 WO PCT/GB1992/002399 patent/WO1993014076A1/en not_active Ceased
- 1992-12-24 NZ NZ246205A patent/NZ246205A/en unknown
- 1992-12-24 BR BR9207030A patent/BR9207030A/pt not_active Application Discontinuation
- 1992-12-24 AU AU31697/93A patent/AU668901B2/en not_active Ceased
- 1992-12-24 DE DE69229834T patent/DE69229834T2/de not_active Expired - Fee Related
- 1992-12-24 EP EP93900365A patent/EP0620817B1/en not_active Expired - Lifetime
- 1992-12-24 HU HU9402042A patent/HUT70513A/hu not_active IP Right Cessation
-
1993
- 1993-01-05 IL IL104305A patent/IL104305A/en not_active IP Right Cessation
- 1993-01-06 TW TW082100059A patent/TW265337B/zh active
- 1993-01-07 MX MX9300031A patent/MX9300031A/es not_active IP Right Cessation
- 1993-01-07 PH PH45533A patent/PH30268A/en unknown
- 1993-01-08 ZA ZA93141A patent/ZA93141B/xx unknown
-
1994
- 1994-07-07 FI FI943247A patent/FI106200B/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| HU9402042D0 (en) | 1994-09-28 |
| ES2134835T3 (es) | 1999-10-16 |
| GB9200293D0 (en) | 1992-02-26 |
| JPH07502739A (ja) | 1995-03-23 |
| GB2263110A (en) | 1993-07-14 |
| JP3274865B2 (ja) | 2002-04-15 |
| RU94039542A (ru) | 1996-08-10 |
| DE69229834D1 (de) | 1999-09-23 |
| EP0620817B1 (en) | 1999-08-18 |
| GB2263110B (en) | 1995-08-09 |
| IL104305A0 (en) | 1993-05-13 |
| EP0620817A1 (en) | 1994-10-26 |
| FI943247A0 (fi) | 1994-07-07 |
| KR100283345B1 (ko) | 2001-03-02 |
| US5532242A (en) | 1996-07-02 |
| NZ246205A (en) | 1996-12-20 |
| AU668901B2 (en) | 1996-05-23 |
| AU3169793A (en) | 1993-08-03 |
| HUT70513A (en) | 1995-10-30 |
| BR9207030A (pt) | 1995-12-05 |
| FI943247L (fi) | 1994-07-07 |
| FI106200B (fi) | 2000-12-15 |
| DE69229834T2 (de) | 2000-01-13 |
| TW265337B (ja) | 1995-12-11 |
| GB9227001D0 (en) | 1993-02-17 |
| IL104305A (en) | 1998-04-05 |
| WO1993014076A1 (en) | 1993-07-22 |
| CA2125182A1 (en) | 1993-07-22 |
| PH30268A (en) | 1997-02-20 |
| MX9300031A (es) | 1993-07-01 |
| RU2128653C1 (ru) | 1999-04-10 |
| ATE183504T1 (de) | 1999-09-15 |
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