ZA200903648B - Process for the preparation of abacavir - Google Patents

Process for the preparation of abacavir

Info

Publication number: ZA200903648B
Authority: ZA; South Africa
Prior art keywords: abacavir; preparation; compound; reacting; compound obtained
Prior art date: 2006-12-21

Application number

ZA200903648A

Other languages

English (en)

Inventor

Ruperez Jorge Medrano

Pardo Julio Campon

Rius Laia Elias

Maimo Ramon Berenguer

Original Assignee

Esteve Quimica Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-12-21

Filing date

2007-12-20

Publication date

2010-08-25

2007-12-20 Application filed by Esteve Quimica Sa filed Critical Esteve Quimica Sa

2010-08-25 Publication of ZA200903648B publication Critical patent/ZA200903648B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA200903648A 2006-12-21 2007-12-20 Process for the preparation of abacavir ZA200903648B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP06126797A EP1939196A1 (en)	2006-12-21	2006-12-21	Process for the preparation of abacavir

Publications (1)

Publication Number	Publication Date
ZA200903648B true ZA200903648B (en)	2010-08-25

Family

ID=37912446

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200903648A ZA200903648B (en)	2006-12-21	2007-12-20	Process for the preparation of abacavir

Country Status (18)

Country	Link
US (1)	US8097723B2 (xx)
EP (2)	EP1939196A1 (xx)
JP (1)	JP5166438B2 (xx)
KR (1)	KR20090094025A (xx)
CN (1)	CN101563346B (xx)
AT (1)	ATE473979T1 (xx)
AU (1)	AU2007336195A1 (xx)
CA (1)	CA2670432A1 (xx)
DE (1)	DE602007007824D1 (xx)
ES (1)	ES2348197T3 (xx)
IL (1)	IL198965A (xx)
MX (1)	MX2009006231A (xx)
NO (1)	NO20092375L (xx)
PL (1)	PL2125814T3 (xx)
RU (1)	RU2447073C2 (xx)
SI (1)	SI2125814T1 (xx)
WO (1)	WO2008074874A1 (xx)
ZA (1)	ZA200903648B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1905772A1 (en) *	2006-09-28	2008-04-02	Esteve Quimica, S.A.	Process for the preparation of abacavir
EP2085397A1 (en)	2008-01-21	2009-08-05	Esteve Quimica, S.A.	Crystalline form of abacavir
EA028518B1 (ru) *	2012-01-03	2017-11-30	Селлсьютикс Корпорейшн	Карбоциклические нуклеозиды, их фармацевтическое применение и композиции
CN104788451A (zh) *	2014-01-21	2015-07-22	浙江九洲药业股份有限公司	一种阿巴卡韦的制备方法
CN109239253B (zh) *	2018-09-21	2021-07-09	江苏威奇达药业有限公司	一种阿巴卡韦的杂质的高效液相检测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.
GB9402161D0 (en) *	1994-02-04	1994-03-30	Wellcome Found	Chloropyrimidine intermediates
GB0320738D0 (en) *	2003-09-04	2003-10-08	Glaxo Group Ltd	Novel process
EP1905772A1 (en) *	2006-09-28	2008-04-02	Esteve Quimica, S.A.	Process for the preparation of abacavir
WO2008072074A1 (en) *	2006-12-11	2008-06-19	Aurobindo Pharma Limited	An improved process for the preparation of purine derivative
EP2170840A1 (en) *	2007-06-21	2010-04-07	Aurobindo Pharma Ltd	An improved process for preparing purine derivative

2006
- 2006-12-21 EP EP06126797A patent/EP1939196A1/en not_active Withdrawn
2007
- 2007-12-20 KR KR1020097014227A patent/KR20090094025A/ko not_active Withdrawn
- 2007-12-20 JP JP2009542076A patent/JP5166438B2/ja not_active Expired - Fee Related
- 2007-12-20 US US12/520,510 patent/US8097723B2/en not_active Expired - Fee Related
- 2007-12-20 CN CN2007800474491A patent/CN101563346B/zh not_active Expired - Fee Related
- 2007-12-20 DE DE602007007824T patent/DE602007007824D1/de active Active
- 2007-12-20 AU AU2007336195A patent/AU2007336195A1/en not_active Abandoned
- 2007-12-20 MX MX2009006231A patent/MX2009006231A/es active IP Right Grant
- 2007-12-20 ZA ZA200903648A patent/ZA200903648B/xx unknown
- 2007-12-20 AT AT07857990T patent/ATE473979T1/de not_active IP Right Cessation
- 2007-12-20 PL PL07857990T patent/PL2125814T3/pl unknown
- 2007-12-20 EP EP07857990A patent/EP2125814B1/en active Active
- 2007-12-20 CA CA002670432A patent/CA2670432A1/en not_active Abandoned
- 2007-12-20 WO PCT/EP2007/064371 patent/WO2008074874A1/en not_active Ceased
- 2007-12-20 ES ES07857990T patent/ES2348197T3/es active Active
- 2007-12-20 SI SI200730377T patent/SI2125814T1/sl unknown
- 2007-12-20 RU RU2009128032/04A patent/RU2447073C2/ru not_active IP Right Cessation
2009
- 2009-05-26 IL IL198965A patent/IL198965A/en not_active IP Right Cessation
- 2009-06-22 NO NO20092375A patent/NO20092375L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20092375L (no)	2009-07-21
ATE473979T1 (de)	2010-07-15
WO2008074874A1 (en)	2008-06-26
ES2348197T3 (es)	2010-12-01
AU2007336195A1 (en)	2008-06-26
KR20090094025A (ko)	2009-09-02
DE602007007824D1 (de)	2010-08-26
IL198965A0 (en)	2010-02-17
CN101563346A (zh)	2009-10-21
JP2010513410A (ja)	2010-04-30
MX2009006231A (es)	2009-06-22
SI2125814T1 (sl)	2010-12-31
JP5166438B2 (ja)	2013-03-21
EP2125814A1 (en)	2009-12-02
RU2447073C2 (ru)	2012-04-10
CN101563346B (zh)	2011-07-27
US20100041883A1 (en)	2010-02-18
RU2009128032A (ru)	2011-01-27
EP1939196A1 (en)	2008-07-02
CA2670432A1 (en)	2008-06-26
PL2125814T3 (pl)	2010-12-31
US8097723B2 (en)	2012-01-17
EP2125814B1 (en)	2010-07-14
IL198965A (en)	2012-08-30

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