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WO2004050663A3 - Procede ameliore de preparation de cefuroxime sodique - Google Patents

Procede ameliore de preparation de cefuroxime sodique Download PDF

Info

Publication number
WO2004050663A3
WO2004050663A3 PCT/IB2003/005563 IB0305563W WO2004050663A3 WO 2004050663 A3 WO2004050663 A3 WO 2004050663A3 IB 0305563 W IB0305563 W IB 0305563W WO 2004050663 A3 WO2004050663 A3 WO 2004050663A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
improved process
cefuroxime sodium
sodium
cefuroxime
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2003/005563
Other languages
English (en)
Other versions
WO2004050663A2 (fr
Inventor
Pandurang Balwant Deshpande
Pramod Narayan Deshpande
Bhausaheb Pandharin Khadangale
Gautam Kumar Das
John Muthiah Raja Jeyakumar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Pharma Ltd
Original Assignee
Orchid Chemicals and Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/310,068 external-priority patent/US20040092735A1/en
Application filed by Orchid Chemicals and Pharmaceuticals Ltd filed Critical Orchid Chemicals and Pharmaceuticals Ltd
Priority to AU2003283660A priority Critical patent/AU2003283660A1/en
Publication of WO2004050663A2 publication Critical patent/WO2004050663A2/fr
Publication of WO2004050663A3 publication Critical patent/WO2004050663A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

L'invention concerne un procédé amélioré de préparation de céfuroxime sodique stérile représenté par la formule (I).
PCT/IB2003/005563 2002-12-05 2003-12-03 Procede ameliore de preparation de cefuroxime sodique Ceased WO2004050663A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003283660A AU2003283660A1 (en) 2002-12-05 2003-12-03 An improved process for the preparation of cefuroxime sodium

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/310,068 2002-12-05
US10/310,068 US20040092735A1 (en) 2002-11-08 2002-12-05 Process for the preparation of cefuroxime sodium
IN219CH2003 2003-03-17
IN219/MAS/2003 2003-03-17

Publications (2)

Publication Number Publication Date
WO2004050663A2 WO2004050663A2 (fr) 2004-06-17
WO2004050663A3 true WO2004050663A3 (fr) 2004-10-28

Family

ID=32472234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2003/005563 Ceased WO2004050663A2 (fr) 2002-12-05 2003-12-03 Procede ameliore de preparation de cefuroxime sodique

Country Status (1)

Country Link
WO (1) WO2004050663A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008132574A1 (fr) * 2007-04-27 2008-11-06 Parabolic Drugs Limited Purification de l'acide céfuroxime
WO2008155615A2 (fr) * 2007-06-18 2008-12-24 Orchid Chemicals & Pharmaceuticals Limited Procédé perfectionné pour la préparation d'un antibiotique de la famille des céphalosporines
CN101475579B (zh) * 2009-01-20 2011-02-09 广州白云山天心制药股份有限公司 一种稳定的头孢呋辛钠及其制备方法
CN102295653A (zh) * 2010-06-28 2011-12-28 广州白云山制药股份有限公司广州白云山化学制药厂 头孢呋辛钠的一步法回收制备方法
CN101967156B (zh) * 2010-09-26 2012-07-18 石药集团中诺药业（石家庄）有限公司 一种头孢呋辛钠重结晶的方法
CN102070572B (zh) * 2010-12-17 2012-10-03 山东金城医药化工股份有限公司 一种从呋喃铵盐废渣中回收制备呋喃酮酸的方法
CN102702231B (zh) * 2012-06-18 2014-10-29 山东大学 一种3-去氨甲酰基-头孢呋辛酸的制备方法
CN103044452A (zh) * 2013-01-10 2013-04-17 潘行远 一种低水分、高稳定性的无菌头孢呋辛钠的制备方法
CN103102357B (zh) * 2013-02-21 2016-01-13 广东立国制药有限公司 一种头孢呋辛钠的合成方法
CN103819490B (zh) * 2014-03-20 2016-03-30 悦康药业集团有限公司 一种头孢呋辛钠化合物
CN104910187A (zh) * 2015-05-28 2015-09-16 浙江长典医药有限公司 一种小儿用头孢呋辛钠化合物实体及其制剂
CN105440055B (zh) * 2015-12-30 2017-11-07 广东金城金素制药有限公司 一种原研制品质头孢呋辛酸及其药物制剂
CN108440568B (zh) * 2018-04-11 2019-04-02 广东立国制药有限公司 一种去氨甲酰基头孢呋辛的制备方法
CN109988183B (zh) * 2019-04-17 2020-12-08 广东立国制药有限公司 一种头孢呋辛酸的中间体的环保制备方法
CN111440196A (zh) * 2020-05-22 2020-07-24 山东金城柯瑞化学有限公司 一种镍基催化合成3-去氨甲酰基头孢呋辛酸的方法
CN112480146B (zh) * 2020-10-30 2022-02-22 浙江惠迪森药业有限公司 一种头孢呋辛酸混合溶剂化物、晶型及制备方法
CN113788843B (zh) * 2021-09-30 2022-07-19 海南海灵化学制药有限公司 一种注射用头孢呋辛钠的制备工艺

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
US4277601A (en) * 1979-02-15 1981-07-07 Glaxo Group Limited Preparation of sodium cefuroxime
US4284767A (en) * 1978-04-07 1981-08-18 Glaxo Group Limited Process for preparing 3-carbamoyloxymethyl cephalosporins
US4775750A (en) * 1983-07-29 1988-10-04 Glaxo Group Limited Process for preparing sodium cefuroxime
WO2002020532A1 (fr) * 2000-09-11 2002-03-14 Biochemie Gesellschaft M.B.H. Intermediaires dans la production de cephalosporine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
US4284767A (en) * 1978-04-07 1981-08-18 Glaxo Group Limited Process for preparing 3-carbamoyloxymethyl cephalosporins
US4277601A (en) * 1979-02-15 1981-07-07 Glaxo Group Limited Preparation of sodium cefuroxime
US4775750A (en) * 1983-07-29 1988-10-04 Glaxo Group Limited Process for preparing sodium cefuroxime
WO2002020532A1 (fr) * 2000-09-11 2002-03-14 Biochemie Gesellschaft M.B.H. Intermediaires dans la production de cephalosporine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WILSON, E. M.: "A tale of two cephalosporins.", CHEMISTRY AND INDUSTRY, 1984, pages 217 - 221, XP001180706 *

Also Published As

Publication number Publication date
WO2004050663A2 (fr) 2004-06-17

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