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UY28084A1 - Derivados antivirales de nucleosidos - Google Patents

Derivados antivirales de nucleosidos

Info

Publication number
UY28084A1
UY28084A1 UY28084A UY28084A UY28084A1 UY 28084 A1 UY28084 A1 UY 28084A1 UY 28084 A UY28084 A UY 28084A UY 28084 A UY28084 A UY 28084A UY 28084 A1 UY28084 A1 UY 28084A1
Authority
UY
Uruguay
Prior art keywords
nucleosid
nucleotide
compounds
treatment
present
Prior art date
Application number
UY28084A
Other languages
English (en)
Inventor
David B Smith
Josepharmstrong Martin
Keshab Sarma
Mark Smith
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32329161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY28084(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of UY28084A1 publication Critical patent/UY28084A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencinn e refiere a los derivados de nucleótido para el tratamiento de las infecciones de la Hepatitis C viral incluyendo compuestos de la fórmula I, composiciones farmacéuticas que comprenden estos compuestos y métodos para el tratamiento o profilaxis de enfermedades mediadas por el Virus de la Hepatitis C que emplea dichos compuestos en monoterapia o en terapia de combinación. La presente invencinn posterior suministra un proceso para la preparación de un nucleótido de pirimidina 1', 3',4'- triacilo de un nucleótido N, 1', 3', 4'- tetraacilpirimidina.
UY28084A 2002-11-19 2003-11-17 Derivados antivirales de nucleosidos UY28084A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42744702P 2002-11-19 2002-11-19
US48397003P 2003-07-01 2003-07-01

Publications (1)

Publication Number Publication Date
UY28084A1 true UY28084A1 (es) 2004-05-31

Family

ID=32329161

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28084A UY28084A1 (es) 2002-11-19 2003-11-17 Derivados antivirales de nucleosidos

Country Status (29)

Country Link
US (1) US6846810B2 (es)
EP (1) EP1565481B1 (es)
JP (1) JP4362450B2 (es)
KR (1) KR100676662B1 (es)
AR (1) AR042192A1 (es)
AT (1) ATE335755T1 (es)
AU (1) AU2003288064B2 (es)
BR (1) BR0316407A (es)
CA (1) CA2504846C (es)
CO (1) CO5550501A2 (es)
CY (1) CY1106207T1 (es)
DE (1) DE60307503T2 (es)
DK (1) DK1565481T3 (es)
ES (1) ES2270136T3 (es)
HR (1) HRP20050417B1 (es)
IL (1) IL168266A (es)
JO (1) JO2403B1 (es)
MX (1) MXPA05005282A (es)
MY (1) MY136229A (es)
NO (1) NO330424B1 (es)
NZ (1) NZ539644A (es)
PA (1) PA8588501A1 (es)
PE (1) PE20040836A1 (es)
PL (1) PL210967B1 (es)
PT (1) PT1565481E (es)
RU (1) RU2327701C2 (es)
TW (1) TWI332507B (es)
UY (1) UY28084A1 (es)
WO (1) WO2004046159A1 (es)

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