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UA91686C2 - Biochemical synhesis of 1.4-butandiamine - Google Patents

Biochemical synhesis of 1.4-butandiamine

Info

Publication number
UA91686C2
UA91686C2 UAA200701586A UAA200701586A UA91686C2 UA 91686 C2 UA91686 C2 UA 91686C2 UA A200701586 A UAA200701586 A UA A200701586A UA A200701586 A UAA200701586 A UA A200701586A UA 91686 C2 UA91686 C2 UA 91686C2
Authority
UA
Ukraine
Prior art keywords
butandiamine
odc
biochemical
synhesis
increased
Prior art date
Application number
UAA200701586A
Other languages
English (en)
Ukrainian (uk)
Inventor
Катрин Эпельман
Петрус Мартинус Матеус Носсин
Сусанна Мария Кремер
Марсель Герхардус Вубболтс
Original Assignee
ДСМ АйПи АСЕТС Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДСМ АйПи АСЕТС Б.В. filed Critical ДСМ АйПи АСЕТС Б.В.
Publication of UA91686C2 publication Critical patent/UA91686C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01053—N-carbamoylputrescine amidase (3.5.1.53)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03011—Agmatinase (3.5.3.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03012—Agmatine deiminase (3.5.3.12)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01017—Ornithine decarboxylase (4.1.1.17)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретение относится к способу биохимического синтеза в промышленном масштабе 1,4-бутандиамина в микроорганизме, который имеет повышенный уровень активности орнитиндекарбоксилазы (ODC), где повышенную активность (ODC) получают с помощью сверхэкспрессии гена, который кодирует ODC с увеличенной транскрипционной и/или трансляционной эффективностью с использованием сильного регулированного промотора, и где образованный в микроорганизме 1,4-бутандиамин секретируется в среду ферментации и извлекается из среды ферментации.
UAA200701586A 2004-07-15 2005-11-07 Biochemical synhesis of 1.4-butandiamine UA91686C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04077047 2004-07-15
PCT/EP2005/007608 WO2006005604A1 (en) 2004-07-15 2005-07-11 Biochemical synthesis of 1,4-butanediamine

Publications (1)

Publication Number Publication Date
UA91686C2 true UA91686C2 (en) 2010-08-25

Family

ID=34928371

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200701586A UA91686C2 (en) 2004-07-15 2005-11-07 Biochemical synhesis of 1.4-butandiamine

Country Status (18)

Country Link
US (2) US9523083B2 (ru)
EP (2) EP2236613B1 (ru)
JP (2) JP5010470B2 (ru)
CN (1) CN101006183B (ru)
AT (1) ATE504658T1 (ru)
AU (1) AU2005261862B2 (ru)
BR (1) BRPI0513362A (ru)
CA (1) CA2571531C (ru)
DE (1) DE602005027356D1 (ru)
EA (1) EA011232B1 (ru)
MX (1) MX2007000565A (ru)
MY (1) MY148119A (ru)
NZ (1) NZ552628A (ru)
PL (2) PL2236613T3 (ru)
TW (1) TWI354026B (ru)
UA (1) UA91686C2 (ru)
WO (1) WO2006005604A1 (ru)
ZA (1) ZA200700072B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5010470B2 (ja) * 2004-07-15 2012-08-29 ディーエスエム アイピー アセッツ ビー．ブイ． １，４−ブタンジアミンの生化学合成
CA2700510C (en) 2008-04-10 2016-07-12 Korea Advanced Institute Of Science And Technology Mutant microorganisms having high ability to produce putrescine and method for producing putrescine using the same
KR101930540B1 (ko) * 2009-05-07 2019-03-15 게노마티카 인코포레이티드 아디페이트, 헥사메틸렌디아민 및 6-아미노카프로산의 생합성을 위한 미생물 및 방법
JP5776907B2 (ja) * 2009-07-24 2015-09-09 ディーエスエム アイピー アセッツ ビー．ブイ． Ｎ−アシル保護またはｎ−グアニジル保護１，４−ブタンジアミン前駆体を介する１，４−ブタンジアミンの調製方法
US10683521B2 (en) * 2012-06-19 2020-06-16 Nanyang Technological University Expression construct for sensing cell density and substrate availability and its use in conversion of hydroxycinnamic acids
CN103451123B (zh) * 2013-06-08 2015-10-21 江苏省农业科学院 溶酪大球菌及其制备方法和应用
JP2017158434A (ja) * 2014-07-22 2017-09-14 協同乳業株式会社 バクテリア混合培養によるプトレッシン製造方法
CN104152478A (zh) * 2014-07-31 2014-11-19 洛阳华荣生物技术有限公司 一种生物转化联产d-精氨酸和胍基丁胺的方法
KR102246288B1 (ko) 2020-08-13 2021-04-29 씨제이제일제당 주식회사 퓨트레신 생산 미생물 및 이를 이용한 퓨트레신 생산방법
CN112522171A (zh) * 2020-12-18 2021-03-19 浙江中山化工集团股份有限公司 一种工程菌、含鸟氨酸溶液的处理方法及试剂盒
CN113061562B (zh) * 2021-03-22 2022-09-27 江南大学 一种利用钝齿棒杆菌发酵生产1,4-丁二胺的方法
JPWO2023157816A1 (ru) * 2022-02-15 2023-08-24

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2130948A (en) 1937-04-09 1938-09-20 Du Pont Synthetic fiber
FR2729775B1 (fr) 1995-01-23 1997-02-21 France Telecom Terminal a lecteur de carte et procede de traitement multi-applicatif d'un tel terminal
ES2088826B1 (es) * 1995-02-10 1997-06-01 Taguidell Sociedad Limitada Procedimiento de obtencion de las diaminas putrescina y cadaverina a partir de productos naturales tratados, su uso como aditivo en abonos, y abono correspondiente.
FI980551A7 (fi) * 1998-03-11 1999-09-12 Valtion Teknillinen Transformoidut mikro-organismit, joilla on parannettuja ominaisuuksia
WO2001011062A2 (en) * 1999-08-10 2001-02-15 John Innes Centre Polyamine accumulation in plants
DE10161412A1 (de) * 2001-12-13 2003-07-03 Aventis Pharma Gmbh Verfahren zur Bestimmung der Aktivität der Ornithin-Decarboxylase sowie zur Identifizierung von Effektoren der Ornithin-Decarboxylase-Aktivität
JP5010470B2 (ja) * 2004-07-15 2012-08-29 ディーエスエム アイピー アセッツ ビー．ブイ． １，４−ブタンジアミンの生化学合成

Also Published As

Publication number Publication date
CN101006183B (zh) 2011-07-27
US20160319311A1 (en) 2016-11-03
CN101006183A (zh) 2007-07-25
AU2005261862B2 (en) 2010-08-26
TWI354026B (en) 2011-12-11
ATE504658T1 (de) 2011-04-15
JP2008505652A (ja) 2008-02-28
MX2007000565A (es) 2007-04-02
EP2236613A1 (en) 2010-10-06
WO2006005604A1 (en) 2006-01-19
NZ552628A (en) 2009-09-25
EP1781799A1 (en) 2007-05-09
PL1781799T3 (pl) 2011-07-29
CA2571531A1 (en) 2006-01-19
US9523083B2 (en) 2016-12-20
JP2012130343A (ja) 2012-07-12
EP2236613B1 (en) 2015-05-27
AU2005261862A1 (en) 2006-01-19
DE602005027356D1 (de) 2011-05-19
TW200613558A (en) 2006-05-01
EA011232B1 (ru) 2009-02-27
CA2571531C (en) 2016-02-16
ZA200700072B (en) 2008-05-28
JP5010470B2 (ja) 2012-08-29
EP1781799B1 (en) 2011-04-06
PL2236613T3 (pl) 2015-11-30
MY148119A (en) 2013-02-28
US20090275093A1 (en) 2009-11-05
EA200700330A1 (ru) 2007-06-29
BRPI0513362A (pt) 2008-05-06

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