UA85583C2 - Применение ротиготина для профилактики и лечения синдрома паркинсона (плюс) - Google Patents
Применение ротиготина для профилактики и лечения синдрома паркинсона (плюс)Info
- Publication number
- UA85583C2 UA85583C2 UAA200609686A UAA200609686A UA85583C2 UA 85583 C2 UA85583 C2 UA 85583C2 UA A200609686 A UAA200609686 A UA A200609686A UA A200609686 A UAA200609686 A UA A200609686A UA 85583 C2 UA85583 C2 UA 85583C2
- Authority
- UA
- Ukraine
- Prior art keywords
- esters
- rotigotine
- preventing
- treating parkinson
- plus syndrome
- Prior art date
Links
- KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 title abstract 3
- 229960003179 rotigotine Drugs 0.000 title abstract 3
- 208000011580 syndromic disease Diseases 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000000651 prodrug Substances 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 abstract 1
- 150000001241 acetals Chemical class 0.000 abstract 1
- 125000005041 acyloxyalkyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 abstract 1
- 125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- -1 oxythiocarbonyl esters Chemical class 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003871 sulfonates Chemical class 0.000 abstract 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 abstract 1
- 150000003558 thiocarbamic acid derivatives Chemical class 0.000 abstract 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004014841A DE102004014841B4 (de) | 2004-03-24 | 2004-03-24 | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA85583C2 true UA85583C2 (ru) | 2009-02-10 |
Family
ID=34963175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200609686A UA85583C2 (ru) | 2004-03-24 | 2005-03-22 | Применение ротиготина для профилактики и лечения синдрома паркинсона (плюс) |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7872041B2 (ru) |
| EP (1) | EP1727539B1 (ru) |
| JP (1) | JP4801042B2 (ru) |
| KR (1) | KR101140452B1 (ru) |
| CN (1) | CN100581542C (ru) |
| AT (1) | ATE376828T1 (ru) |
| AU (1) | AU2005226911B2 (ru) |
| CA (1) | CA2559683C (ru) |
| DE (2) | DE102004014841B4 (ru) |
| EA (1) | EA011278B1 (ru) |
| ES (1) | ES2296156T3 (ru) |
| MX (1) | MXPA06010747A (ru) |
| NO (1) | NO20064792L (ru) |
| NZ (1) | NZ550025A (ru) |
| UA (1) | UA85583C2 (ru) |
| WO (1) | WO2005092331A1 (ru) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041479A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| US8246979B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| DE10361259A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes |
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途 |
| EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
| US8505540B2 (en) | 2007-11-13 | 2013-08-13 | Apnicure, Inc. | Methods and systems for improving airway patency |
| PT2215072E (pt) | 2007-11-28 | 2015-10-14 | Ucb Pharma Gmbh | Forma polimórfica de rotigotina |
| EP2201941A1 (de) | 2008-12-29 | 2010-06-30 | UCB Pharma GmbH | Pflaster-Herstellungstechnologie |
| EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
| CA2767068C (en) | 2009-12-22 | 2016-09-27 | Ucb Pharma Gmbh | Polyvinylpyrrolidone for the stabilization of a solid dispersion of the non-crystalline form of rotigotine |
| WO2011095539A2 (en) | 2010-02-05 | 2011-08-11 | Ucb Pharma Gmbh | Novel process for the preparation of nitrogen substituted aminotetralins derivatives |
| MX2012013818A (es) | 2010-06-25 | 2013-01-24 | Ucb Pharma Gmbh | Procesos para la resolucion de derivados de (s)-5-alcoxi-2-amino-t etralina sustituida con nitrogeno. |
| US8979823B2 (en) | 2011-02-09 | 2015-03-17 | Apnicure, Inc. | Saliva management system with continuous flow through oral device |
| EP2559435A1 (en) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke |
| US8383093B1 (en) | 2011-11-01 | 2013-02-26 | Serina Therapeutics, Inc. | Subcutaneous delivery of poly(oxazoline) conjugates |
| DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
| DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
| WO2013075822A1 (en) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system (tts) with rotigotine |
| TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片 |
| CA2916183C (en) | 2013-07-03 | 2022-03-29 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with electronic component |
| WO2015177204A1 (en) | 2014-05-20 | 2015-11-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
| CA2948221C (en) | 2014-05-20 | 2022-11-22 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
| WO2015177209A1 (en) | 2014-05-20 | 2015-11-26 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
| US9956201B2 (en) | 2014-07-21 | 2018-05-01 | Spriaso Llc | Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms |
| FI3854388T3 (fi) | 2020-01-24 | 2023-11-27 | Luye Pharma Switzerland Ag | Transdermaalinen hoitojärjestelmä, jossa on vaikuttava aine rotigotiini ja ainakin yksi ei-amiiniresistentti silikoniliima |
| FR3106978B1 (fr) | 2020-02-11 | 2024-04-26 | Olivier Petitjean | Utilisation d'une molecule inhibitrice de la production de ros d'origine mitochondriale telle que l'anethole trithione pour traiter la maladie de parkinson |
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| DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| EP1708706A1 (en) * | 2004-01-22 | 2006-10-11 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and a dopamine agonist |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| CA2568850A1 (en) | 2004-08-02 | 2006-02-16 | Schwarz Pharma Ag | Indolizine carboxamides and the aza and diaza derivatives thereof |
| WO2006039532A2 (en) | 2004-09-29 | 2006-04-13 | Schwarz Pharma, Inc. | Transdermal therapeutic system for parkinson’s disease |
| DE102004054634A1 (de) | 2004-11-12 | 2006-05-18 | Schwarz Pharma Ag | Azaindolcarboxamide |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途 |
| EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
| PT2215072E (pt) * | 2007-11-28 | 2015-10-14 | Ucb Pharma Gmbh | Forma polimórfica de rotigotina |
-
2004
- 2004-03-24 DE DE102004014841A patent/DE102004014841B4/de not_active Expired - Fee Related
-
2005
- 2005-03-22 UA UAA200609686A patent/UA85583C2/ru unknown
- 2005-03-22 WO PCT/EP2005/003013 patent/WO2005092331A1/de not_active Ceased
- 2005-03-22 NZ NZ550025A patent/NZ550025A/en not_active IP Right Cessation
- 2005-03-22 ES ES05728686T patent/ES2296156T3/es not_active Expired - Lifetime
- 2005-03-22 DE DE502005001828T patent/DE502005001828D1/de not_active Expired - Lifetime
- 2005-03-22 EP EP05728686A patent/EP1727539B1/de not_active Expired - Lifetime
- 2005-03-22 AU AU2005226911A patent/AU2005226911B2/en not_active Ceased
- 2005-03-22 JP JP2007504337A patent/JP4801042B2/ja not_active Expired - Fee Related
- 2005-03-22 CN CN200580009165A patent/CN100581542C/zh not_active Expired - Fee Related
- 2005-03-22 KR KR1020067021135A patent/KR101140452B1/ko not_active Expired - Fee Related
- 2005-03-22 MX MXPA06010747A patent/MXPA06010747A/es active IP Right Grant
- 2005-03-22 US US10/593,964 patent/US7872041B2/en not_active Expired - Fee Related
- 2005-03-22 AT AT05728686T patent/ATE376828T1/de not_active IP Right Cessation
- 2005-03-22 CA CA2559683A patent/CA2559683C/en not_active Expired - Fee Related
- 2005-03-22 EA EA200601746A patent/EA011278B1/ru not_active IP Right Cessation
-
2006
- 2006-10-23 NO NO20064792A patent/NO20064792L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007530484A (ja) | 2007-11-01 |
| KR20060130730A (ko) | 2006-12-19 |
| NO20064792L (no) | 2006-10-23 |
| AU2005226911A1 (en) | 2005-10-06 |
| DE102004014841A1 (de) | 2005-10-13 |
| EA011278B1 (ru) | 2009-02-27 |
| DE502005001828D1 (de) | 2007-12-13 |
| WO2005092331A1 (de) | 2005-10-06 |
| NZ550025A (en) | 2010-07-30 |
| HK1100765A1 (en) | 2007-09-28 |
| EP1727539A1 (de) | 2006-12-06 |
| JP4801042B2 (ja) | 2011-10-26 |
| ATE376828T1 (de) | 2007-11-15 |
| EP1727539B1 (de) | 2007-10-31 |
| KR101140452B1 (ko) | 2012-04-30 |
| CA2559683C (en) | 2012-07-17 |
| EA200601746A1 (ru) | 2007-04-27 |
| DE102004014841B4 (de) | 2006-07-06 |
| CA2559683A1 (en) | 2005-10-06 |
| US7872041B2 (en) | 2011-01-18 |
| US20070191470A1 (en) | 2007-08-16 |
| CN100581542C (zh) | 2010-01-20 |
| AU2005226911B2 (en) | 2011-02-10 |
| ES2296156T3 (es) | 2008-04-16 |
| MXPA06010747A (es) | 2006-12-15 |
| CN1960724A (zh) | 2007-05-09 |
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