UA81323C2 - Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3 - Google Patents
Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3 Download PDFInfo
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- UA81323C2 UA81323C2 UAA200512752A UAA200512752A UA81323C2 UA 81323 C2 UA81323 C2 UA 81323C2 UA A200512752 A UAA200512752 A UA A200512752A UA A200512752 A UAA200512752 A UA A200512752A UA 81323 C2 UA81323 C2 UA 81323C2
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- 108010053099 Vascular Endothelial Growth Factor Receptor-2 Proteins 0.000 title abstract 2
- 108010053100 Vascular Endothelial Growth Factor Receptor-3 Proteins 0.000 title abstract 2
- ZZQFWOJVCQAPCL-UHFFFAOYSA-N anthracen-1-amine;1h-pyridin-2-one Chemical class O=C1C=CC=CN1.C1=CC=C2C=C3C(N)=CC=CC3=CC2=C1 ZZQFWOJVCQAPCL-UHFFFAOYSA-N 0.000 title abstract 2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10327719A DE10327719A1 (de) | 2003-06-13 | 2003-06-13 | VEGFR-2 und VEGFR-3 Inhibitorische Anthranylamidpyridone |
| PCT/EP2004/006236 WO2004111005A1 (de) | 2003-06-13 | 2004-06-09 | Vegfr-2 und vegfr-3 inhibitorische anthranylamidpyridone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA81323C2 true UA81323C2 (en) | 2007-12-25 |
Family
ID=33520741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200512752A UA81323C2 (en) | 2003-06-13 | 2004-09-06 | Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1633713A1 (de) |
| JP (1) | JP2006527228A (de) |
| KR (1) | KR20060021887A (de) |
| CN (1) | CN1805936A (de) |
| AU (1) | AU2004247377A1 (de) |
| BR (1) | BRPI0411360A (de) |
| CA (1) | CA2526041A1 (de) |
| CR (1) | CR8127A (de) |
| DE (1) | DE10327719A1 (de) |
| EA (1) | EA200501885A1 (de) |
| EC (1) | ECSP066280A (de) |
| IL (1) | IL171898A0 (de) |
| MX (1) | MXPA05013586A (de) |
| NO (1) | NO20060196L (de) |
| RS (1) | RS20050831A (de) |
| UA (1) | UA81323C2 (de) |
| WO (1) | WO2004111005A1 (de) |
| ZA (1) | ZA200600291B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060071812A (ko) * | 2004-12-22 | 2006-06-27 | 주식회사 엘지생명과학 | 신규한 3-(2-아미노-6-피리디닐)-4-히드록시페닐 아민유도체 |
| US9376393B2 (en) * | 2012-01-05 | 2016-06-28 | Clanotech Ab | Quinoline compounds which are anti-angiogenic integrin alpha5 beta1 inhibitors for use in the treatment of fibrosis or fibrosis-related diseases |
| CN106496107A (zh) * | 2016-08-31 | 2017-03-15 | 浙江永宁药业股份有限公司 | Vegfr‑2抑制剂及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA71587C2 (uk) * | 1998-11-10 | 2004-12-15 | Шерінг Акцієнгезелльшафт | Аміди антранілової кислоти та їхнє застосування як лікарських засобів |
| GB9824579D0 (en) * | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
| DE10023486C1 (de) * | 2000-05-09 | 2002-03-14 | Schering Ag | Ortho substituierte Anthranilsäureamide und deren Verwendung als Arzneimittel |
| MXPA03010099A (es) * | 2001-05-08 | 2004-03-10 | Schering Ag | Amidas de antranilamida-piridina selectivas como inhibidores de vegfr-2 y vegfr-3. |
| GB0126902D0 (en) * | 2001-11-08 | 2002-01-02 | Novartis Ag | Organic compounds |
| DE10228090A1 (de) * | 2002-06-19 | 2004-01-15 | Schering Ag | Ausgewählte Anthranylamidpyridinamide und deren Verwendung als Arzneimittel |
-
2003
- 2003-06-13 DE DE10327719A patent/DE10327719A1/de not_active Ceased
-
2004
- 2004-06-09 AU AU2004247377A patent/AU2004247377A1/en not_active Abandoned
- 2004-06-09 BR BRPI0411360-8A patent/BRPI0411360A/pt not_active IP Right Cessation
- 2004-06-09 KR KR1020057023901A patent/KR20060021887A/ko not_active Withdrawn
- 2004-06-09 CN CNA2004800163643A patent/CN1805936A/zh active Pending
- 2004-06-09 EA EA200501885A patent/EA200501885A1/ru unknown
- 2004-06-09 MX MXPA05013586A patent/MXPA05013586A/es unknown
- 2004-06-09 WO PCT/EP2004/006236 patent/WO2004111005A1/de not_active Ceased
- 2004-06-09 RS YUP-2005/0831A patent/RS20050831A/sr unknown
- 2004-06-09 JP JP2006515873A patent/JP2006527228A/ja active Pending
- 2004-06-09 CA CA002526041A patent/CA2526041A1/en not_active Abandoned
- 2004-06-09 EP EP04739742A patent/EP1633713A1/de not_active Withdrawn
- 2004-09-06 UA UAA200512752A patent/UA81323C2/uk unknown
-
2005
- 2005-11-10 IL IL171898A patent/IL171898A0/en unknown
- 2005-12-09 CR CR8127A patent/CR8127A/es not_active Application Discontinuation
-
2006
- 2006-01-12 EC EC2006006280A patent/ECSP066280A/es unknown
- 2006-01-12 NO NO20060196A patent/NO20060196L/no not_active Application Discontinuation
- 2006-01-12 ZA ZA200600291A patent/ZA200600291B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20060196L (no) | 2006-01-12 |
| WO2004111005A1 (de) | 2004-12-23 |
| MXPA05013586A (es) | 2006-03-09 |
| ZA200600291B (en) | 2007-03-28 |
| ECSP066280A (es) | 2006-07-28 |
| DE10327719A1 (de) | 2005-01-20 |
| CR8127A (es) | 2006-05-29 |
| IL171898A0 (en) | 2006-04-10 |
| AU2004247377A1 (en) | 2004-12-23 |
| CA2526041A1 (en) | 2004-12-23 |
| CN1805936A (zh) | 2006-07-19 |
| EP1633713A1 (de) | 2006-03-15 |
| KR20060021887A (ko) | 2006-03-08 |
| EA200501885A1 (ru) | 2006-06-30 |
| BRPI0411360A (pt) | 2006-07-25 |
| RS20050831A (sr) | 2008-04-04 |
| JP2006527228A (ja) | 2006-11-30 |
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