IL171898A0 - Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3 - Google Patents

Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3

Info

Publication number: IL171898A0
Authority: IL; Israel
Prior art keywords: vegfr; anthranylamide; pyridones; inhibit; inhibit vegfr
Prior art date: 2003-06-13

Application number

IL171898A

Other languages

English (en)

Original Assignee

Bayer Schering Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-13

Filing date

2005-11-10

Publication date

2006-04-10

2005-11-10 Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag

2006-04-10 Publication of IL171898A0 publication Critical patent/IL171898A0/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Dermatology (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Hematology (AREA)
Oncology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Surgery (AREA)
Vascular Medicine (AREA)
Physical Education & Sports Medicine (AREA)
Transplantation (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)

IL171898A 2003-06-13 2005-11-10 Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3 IL171898A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10327719A DE10327719A1 (de)	2003-06-13	2003-06-13	VEGFR-2 und VEGFR-3 Inhibitorische Anthranylamidpyridone
PCT/EP2004/006236 WO2004111005A1 (de)	2003-06-13	2004-06-09	Vegfr-2 und vegfr-3 inhibitorische anthranylamidpyridone

Publications (1)

Publication Number	Publication Date
IL171898A0 true IL171898A0 (en)	2006-04-10

Family

ID=33520741

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL171898A IL171898A0 (en)	2003-06-13	2005-11-10	Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3

Country Status (18)

Country	Link
EP (1)	EP1633713A1 (de)
JP (1)	JP2006527228A (de)
KR (1)	KR20060021887A (de)
CN (1)	CN1805936A (de)
AU (1)	AU2004247377A1 (de)
BR (1)	BRPI0411360A (de)
CA (1)	CA2526041A1 (de)
CR (1)	CR8127A (de)
DE (1)	DE10327719A1 (de)
EA (1)	EA200501885A1 (de)
EC (1)	ECSP066280A (de)
IL (1)	IL171898A0 (de)
MX (1)	MXPA05013586A (de)
NO (1)	NO20060196L (de)
RS (1)	RS20050831A (de)
UA (1)	UA81323C2 (de)
WO (1)	WO2004111005A1 (de)
ZA (1)	ZA200600291B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20060071812A (ko) *	2004-12-22	2006-06-27	주식회사 엘지생명과학	신규한 3-(2-아미노-6-피리디닐)-4-히드록시페닐 아민유도체
WO2013103317A1 (en) *	2012-01-05	2013-07-11	Clanotech Ab	Quinoline compounds which are anti-angiogenic integrin alpha5 betal inhibitors for use in the treatment of fibrosis or fibrosis-related diseases
CN106496107A (zh) *	2016-08-31	2017-03-15	浙江永宁药业股份有限公司	Vegfr‑2抑制剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA71587C2 (uk) *	1998-11-10	2004-12-15	Шерінг Акцієнгезелльшафт	Аміди антранілової кислоти та їхнє застосування як лікарських засобів
GB9824579D0 (en) *	1998-11-10	1999-01-06	Novartis Ag	Organic compounds
DE10023486C1 (de) *	2000-05-09	2002-03-14	Schering Ag	Ortho substituierte Anthranilsäureamide und deren Verwendung als Arzneimittel
DE50213703D1 (de) *	2001-05-08	2009-09-03	Bayer Schering Pharma Ag	Selektive anthranylamidpyridinamide als vegfr-2 und vegfr-3 inhibitoren
GB0126902D0 (en) *	2001-11-08	2002-01-02	Novartis Ag	Organic compounds
DE10228090A1 (de) *	2002-06-19	2004-01-15	Schering Ag	Ausgewählte Anthranylamidpyridinamide und deren Verwendung als Arzneimittel

2003
- 2003-06-13 DE DE10327719A patent/DE10327719A1/de not_active Ceased
2004
- 2004-06-09 RS YUP-2005/0831A patent/RS20050831A/sr unknown
- 2004-06-09 MX MXPA05013586A patent/MXPA05013586A/es unknown
- 2004-06-09 AU AU2004247377A patent/AU2004247377A1/en not_active Abandoned
- 2004-06-09 EA EA200501885A patent/EA200501885A1/ru unknown
- 2004-06-09 BR BRPI0411360-8A patent/BRPI0411360A/pt not_active IP Right Cessation
- 2004-06-09 CA CA002526041A patent/CA2526041A1/en not_active Abandoned
- 2004-06-09 KR KR1020057023901A patent/KR20060021887A/ko not_active Withdrawn
- 2004-06-09 CN CNA2004800163643A patent/CN1805936A/zh active Pending
- 2004-06-09 JP JP2006515873A patent/JP2006527228A/ja active Pending
- 2004-06-09 EP EP04739742A patent/EP1633713A1/de not_active Withdrawn
- 2004-06-09 WO PCT/EP2004/006236 patent/WO2004111005A1/de not_active Ceased
- 2004-09-06 UA UAA200512752A patent/UA81323C2/uk unknown
2005
- 2005-11-10 IL IL171898A patent/IL171898A0/en unknown
- 2005-12-09 CR CR8127A patent/CR8127A/es not_active Application Discontinuation
2006
- 2006-01-12 EC EC2006006280A patent/ECSP066280A/es unknown
- 2006-01-12 NO NO20060196A patent/NO20060196L/no not_active Application Discontinuation
- 2006-01-12 ZA ZA200600291A patent/ZA200600291B/en unknown

Also Published As

Publication number	Publication date
UA81323C2 (en)	2007-12-25
BRPI0411360A (pt)	2006-07-25
DE10327719A1 (de)	2005-01-20
CR8127A (es)	2006-05-29
KR20060021887A (ko)	2006-03-08
WO2004111005A1 (de)	2004-12-23
AU2004247377A1 (en)	2004-12-23
RS20050831A (sr)	2008-04-04
MXPA05013586A (es)	2006-03-09
JP2006527228A (ja)	2006-11-30
CA2526041A1 (en)	2004-12-23
ECSP066280A (es)	2006-07-28
CN1805936A (zh)	2006-07-19
EA200501885A1 (ru)	2006-06-30
NO20060196L (no)	2006-01-12
ZA200600291B (en)	2007-03-28
EP1633713A1 (de)	2006-03-15

Publication	Publication Date	Title
PL374610A1 (en)	2005-10-31	Vegfr-2 and vegfr-3 inhibitory anthranylamidopyridines
EP1727498A4 (de)	2009-12-16	Vorrichtungen und verfahren zur endovaskulären behandlung
DE50213703D1 (de)	2009-09-03	Selektive anthranylamidpyridinamide als vegfr-2 und vegfr-3 inhibitoren
EP1576093A4 (de)	2009-07-08	3-desoxyglucoson und haut
AU2003203029A8 (en)	2003-07-30	Improved health-related devices and methods
IL173900A0 (en)	2006-07-05	Dishwasher and method
GB0417989D0 (en)	2004-09-15	Data session notification means and method
GB0306586D0 (en)	2003-04-30	Spectroscpy apparatus and associated technique
EP1643907A4 (de)	2009-08-12	Lumenmessvorrichtungen und verfahren
EP1482985A4 (de)	2006-06-28	Technetium-dipyridin-komplexe und anwendungsverfahren dafür
EP1703943A4 (de)	2009-12-23	Verfahren, gerät und geladene chemikalien zur kontrolle von ionen, molekülen oder elektronen
EP1469813A4 (de)	2008-08-27	Zusätze und produkte mit oligoestern
AU2003243657A8 (en)	2004-01-19	Amino-bicyclic pyrazinones and pyridinones
EG25097A (en)	2011-08-17	Piprazinyl and diazapanyl benzamides and benzthioamides.
GB0412301D0 (en)	2004-07-07	Product and method
IL166479A0 (en)	2006-01-15	Frying system and method
EP1689573A4 (de)	2011-02-09	Sensorsystem und verfahren dafür
AU2003210541A8 (en)	2003-07-30	Health improvement systems and methods
SG117499A1 (en)	2005-12-29	Cleaning member and cleaning method
IL171898A0 (en)	2006-04-10	Anthranylamide pyridones that inhibit vegfr-2 and vegfr-3
GB0426903D0 (en)	2005-01-12	Complexes and methods
IL172704A0 (en)	2006-04-10	Salinosporamides and methods for use thereof
IL175041A0 (en)	2006-08-20	Laminated knitted net and method for making the same
GB0318546D0 (en)	2003-09-10	Quinoxalinones and their use
GB0300764D0 (en)	2003-02-12	Device and method