TWI393563B - 苯并-稠合的雜環磺醯胺衍生物用於治療肥胖之用途 - Google Patents

苯并-稠合的雜環磺醯胺衍生物用於治療肥胖之用途 Download PDF

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Publication number: TWI393563B
Authority: TW; Taiwan
Prior art keywords: benzo; compound; dihydro; group; acid
Prior art date: 2005-12-19

Application number

TW95147358A

Other languages

English (en)

Chinese (zh)

Other versions

TW200744578A (en

Inventor

Virginia L Smith-Swintosky

Allen B Reitz

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-19

Filing date

2006-12-18

Publication date

2013-04-21

2006-12-18 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2007-12-16 Publication of TW200744578A publication Critical patent/TW200744578A/zh

2013-04-21 Application granted granted Critical

2013-04-21 Publication of TWI393563B publication Critical patent/TWI393563B/zh

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239000004299 sodium benzoate Substances 0.000 description 1
235000010234 sodium benzoate Nutrition 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
239000008247 solid mixture Substances 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
235000010356 sorbitol Nutrition 0.000 description 1
239000007921 spray Substances 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
238000007619 statistical method Methods 0.000 description 1
229960004274 stearic acid Drugs 0.000 description 1
239000008174 sterile solution Substances 0.000 description 1
239000003270 steroid hormone Substances 0.000 description 1
150000003431 steroids Chemical class 0.000 description 1
210000002784 stomach Anatomy 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
238000009495 sugar coating Methods 0.000 description 1
IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical compound NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 description 1
PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 description 1
229940032330 sulfuric acid Drugs 0.000 description 1
238000013268 sustained release Methods 0.000 description 1
239000012730 sustained-release form Substances 0.000 description 1
239000005061 synthetic rubber Substances 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
235000012222 talc Nutrition 0.000 description 1
229920002258 tannic acid Polymers 0.000 description 1
229940033123 tannic acid Drugs 0.000 description 1
235000015523 tannic acid Nutrition 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
229960001367 tartaric acid Drugs 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
229940095064 tartrate Drugs 0.000 description 1
229960003604 testosterone Drugs 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
230000037317 transdermal delivery Effects 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
239000000777 urocortin Substances 0.000 description 1
230000004584 weight gain Effects 0.000 description 1
235000019786 weight gain Nutrition 0.000 description 1
UGZADUVQMDAIAO-UHFFFAOYSA-L zinc hydroxide Chemical compound [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 description 1
229940007718 zinc hydroxide Drugs 0.000 description 1
229910021511 zinc hydroxide Inorganic materials 0.000 description 1
229930195724 β-lactose Natural products 0.000 description 1

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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

TW95147358A 2005-12-19 2006-12-18 苯并-稠合的雜環磺醯胺衍生物用於治療肥胖之用途 TWI393563B (zh)

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US75149905P	2005-12-19	2005-12-19

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Country Status (2)

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TW (1)	TWI393563B (uk)
UA (1)	UA96748C2 (uk)

2006
- 2006-12-18 TW TW95147358A patent/TWI393563B/zh not_active IP Right Cessation
- 2006-12-19 UA UAA200809402A patent/UA96748C2/uk unknown

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Andrea Scozzafava et al;"Modulation of carbonic anhydrase activity and its applications in therapy";Expert Opinion on Therapeutic Patents,vol.14,no.5,2004,pages 667-702 *
Bruce E. Maryanoff et al;"Comparison of Sulfamate and Sulfamide groups for the Inhibition of Carbonic Anhydrase-Ⅱ by Using Topiramate as a Structural Platform";Journal of Medicinal Chemistry,vol.48,no.6,2005,pages 1941-1947 *

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Publication number	Publication date
UA96748C2 (uk)	2011-12-12
TW200744578A (en)	2007-12-16

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