TW200801010A - Heterocyclic antiviral compounds - Google Patents
Heterocyclic antiviral compoundsInfo
- Publication number
- TW200801010A TW200801010A TW096105067A TW96105067A TW200801010A TW 200801010 A TW200801010 A TW 200801010A TW 096105067 A TW096105067 A TW 096105067A TW 96105067 A TW96105067 A TW 96105067A TW 200801010 A TW200801010 A TW 200801010A
- Authority
- TW
- Taiwan
- Prior art keywords
- treating
- antagonists
- ccr5
- antiviral compounds
- chemokine
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 102000004274 CCR5 Receptors Human genes 0.000 abstract 2
- 108010017088 CCR5 Receptors Proteins 0.000 abstract 2
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- QFCMBRXRVQRSSF-UHFFFAOYSA-N 1,2,3,3a,4,5,6,6a-octahydropyrrolo[3,4-c]pyrrole Chemical class C1NCC2CNCC21 QFCMBRXRVQRSSF-UHFFFAOYSA-N 0.000 abstract 1
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 abstract 1
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 abstract 1
- 229940122444 Chemokine receptor antagonist Drugs 0.000 abstract 1
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- 239000002559 chemokine receptor antagonist Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77394206P | 2006-02-15 | 2006-02-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200801010A true TW200801010A (en) | 2008-01-01 |
Family
ID=38157829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW096105067A TW200801010A (en) | 2006-02-15 | 2007-02-12 | Heterocyclic antiviral compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070191335A1 (zh) |
| EP (1) | EP1987036A1 (zh) |
| JP (1) | JP2009526803A (zh) |
| KR (1) | KR20080102387A (zh) |
| CN (1) | CN101384596A (zh) |
| AR (1) | AR059571A1 (zh) |
| AU (1) | AU2007216543A1 (zh) |
| BR (1) | BRPI0710474A2 (zh) |
| CA (1) | CA2641389A1 (zh) |
| CL (1) | CL2007000362A1 (zh) |
| IL (1) | IL193107A0 (zh) |
| NO (1) | NO20083585L (zh) |
| RU (1) | RU2008136756A (zh) |
| TW (1) | TW200801010A (zh) |
| WO (1) | WO2007093520A1 (zh) |
| ZA (1) | ZA200806756B (zh) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2641382A1 (en) * | 2006-02-15 | 2007-08-23 | F. Hoffmann-La Roche Ag | Heterocyclic antiviral compounds |
| ATE472549T1 (de) | 2006-09-18 | 2010-07-15 | Hoffmann La Roche | Octahydropyrroloä3,4-cüpyrrolderivate und ihre verwendung als antivirale mittel |
| EP2099454A4 (en) * | 2006-11-17 | 2010-11-10 | Abbott Lab | AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS |
| US8464207B2 (en) * | 2007-10-12 | 2013-06-11 | Novell Intellectual Property Holdings, Inc. | System and method for tracking software changes |
| DE102010025663A1 (de) * | 2010-06-30 | 2012-01-05 | Karl-Heinz Glüsenkamp | Neue beta-Aminoaldehyd-Derivate, Verfahren zu ihrer Herstellung und ihre chemische Verwendung als reaktive Intermediate |
| US20140323306A1 (en) | 2011-11-14 | 2014-10-30 | Basf Se | Substituted 1,2,5-Oxadiazole Compounds and Their Use as Herbicides |
| JP2015519314A (ja) | 2012-04-27 | 2015-07-09 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 置換型ｎ−（テトラゾール−５−イル）−およびｎ−（トリアゾール−５−イル）ピリジン−３−イル−カルボキサミド化合物ならびに除草剤としてのそれらの使用 |
| EA027847B1 (ru) | 2012-04-27 | 2017-09-29 | Басф Се | Замещенные n-(тетразол-5-ил)- и n-(триазол-5-ил)арилкарбоксамидные соединения и их применение в качестве гербицидов |
| CN102718695B (zh) * | 2012-06-25 | 2014-04-02 | 华东师范大学 | 一种氮杂双环[3.3.0]辛烷衍生物的合成方法 |
| AR092211A1 (es) | 2012-09-24 | 2015-04-08 | Merck Patent Ges Mit Beschränkter Haftung | Derivados de hidropirrolopirrol |
| WO2014184058A1 (en) | 2013-05-15 | 2014-11-20 | Basf Se | Substituted 1,2,5-oxadiazole compounds and their use as herbicides |
| CN105209441A (zh) | 2013-05-15 | 2015-12-30 | 巴斯夫欧洲公司 | 取代的n-(四唑-5-基)-和n-(三唑-5-基)芳基羧酰胺化合物及其作为除草剂的用途 |
| EP3022190B1 (en) | 2013-07-18 | 2017-06-28 | Basf Se | N-(1,2,4-triazol-3-yl)-pyridin-2-yl-carboxamide derivatives as herbicides |
| US9902704B2 (en) | 2013-10-10 | 2018-02-27 | Basf Se | Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamide compounds and their use as herbicides |
| WO2015052178A1 (en) | 2013-10-10 | 2015-04-16 | Basf Se | 1,2,5-oxadiazole compounds and their use as herbicides |
| WO2015052173A1 (en) | 2013-10-10 | 2015-04-16 | Basf Se | Tetrazole and triazole compounds and their use as herbicides |
| EP2907807A1 (en) | 2014-02-18 | 2015-08-19 | Basf Se | Benzamide compounds and their use as herbicides |
| KR20180095901A (ko) | 2015-12-17 | 2018-08-28 | 바스프 에스이 | 벤즈아미드 화합물 및 제초제로서 그들의 용도 |
| KR20190026902A (ko) | 2016-07-14 | 2019-03-13 | 화이자 인코포레이티드 | 바닌-1 효소의 억제제로서의 신규 피리미딘 카르복스아미드 |
| AU2018275617A1 (en) | 2017-05-30 | 2019-12-19 | Basf Se | Benzamide compounds and their use as herbicides |
| US20210179569A1 (en) | 2017-05-30 | 2021-06-17 | Basf Se | Benzamide compounds and their use as herbicides ii |
| AR112112A1 (es) | 2017-06-20 | 2019-09-18 | Basf Se | Compuestos de benzamida y su uso como herbicidas |
| AR112342A1 (es) | 2017-07-21 | 2019-10-16 | Basf Se | Compuestos de benzamida y su uso como herbicidas |
| WO2019122345A1 (en) | 2017-12-22 | 2019-06-27 | Basf Se | Benzamide compounds and their use as herbicides |
| WO2019162308A1 (en) | 2018-02-21 | 2019-08-29 | Basf Se | Benzamide compounds and their use as herbicides |
| WO2019162309A1 (en) | 2018-02-21 | 2019-08-29 | Basf Se | Benzamide compounds and their use as herbicides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2297727T3 (es) * | 2004-06-09 | 2008-05-01 | F. Hoffmann-La Roche Ag | Derivados de octahidropirrolo(3,4-c)pirrol y su empleo como agentes antiviricos. |
-
2007
- 2007-02-06 JP JP2008554728A patent/JP2009526803A/ja active Pending
- 2007-02-06 AU AU2007216543A patent/AU2007216543A1/en not_active Abandoned
- 2007-02-06 CA CA002641389A patent/CA2641389A1/en not_active Abandoned
- 2007-02-06 RU RU2008136756/04A patent/RU2008136756A/ru not_active Application Discontinuation
- 2007-02-06 KR KR1020087022382A patent/KR20080102387A/ko not_active Withdrawn
- 2007-02-06 WO PCT/EP2007/051099 patent/WO2007093520A1/en not_active Ceased
- 2007-02-06 CN CNA2007800051374A patent/CN101384596A/zh active Pending
- 2007-02-06 EP EP07704382A patent/EP1987036A1/en not_active Withdrawn
- 2007-02-06 BR BRPI0710474-0A patent/BRPI0710474A2/pt not_active IP Right Cessation
- 2007-02-12 TW TW096105067A patent/TW200801010A/zh unknown
- 2007-02-12 CL CL2007000362A patent/CL2007000362A1/es unknown
- 2007-02-13 AR ARP070100591A patent/AR059571A1/es unknown
- 2007-02-15 US US11/706,807 patent/US20070191335A1/en not_active Abandoned
-
2008
- 2008-07-29 IL IL193107A patent/IL193107A0/en unknown
- 2008-08-05 ZA ZA200806756A patent/ZA200806756B/xx unknown
- 2008-08-19 NO NO20083585A patent/NO20083585L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2008136756A (ru) | 2010-03-20 |
| CL2007000362A1 (es) | 2008-01-11 |
| IL193107A0 (en) | 2009-02-11 |
| AR059571A1 (es) | 2008-04-16 |
| CN101384596A (zh) | 2009-03-11 |
| EP1987036A1 (en) | 2008-11-05 |
| US20070191335A1 (en) | 2007-08-16 |
| KR20080102387A (ko) | 2008-11-25 |
| CA2641389A1 (en) | 2007-08-23 |
| JP2009526803A (ja) | 2009-07-23 |
| BRPI0710474A2 (pt) | 2011-08-16 |
| ZA200806756B (en) | 2009-11-25 |
| WO2007093520A1 (en) | 2007-08-23 |
| NO20083585L (no) | 2008-10-28 |
| AU2007216543A1 (en) | 2007-08-23 |
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