CL2007000362A1 - Compuestos derivados de octahidropirrolo {3,4-c}pirrol sustituidos,antagonistas de los receptores ccr5 de quimioquinas ccr5;composicion farmaceutica;y su uso en el tratamiento o prevencion de infecciones por virus de la inmunodeficiencia humana (vih-1)o para tratar el sida ao el arc. - Google Patents
Compuestos derivados de octahidropirrolo {3,4-c}pirrol sustituidos,antagonistas de los receptores ccr5 de quimioquinas ccr5;composicion farmaceutica;y su uso en el tratamiento o prevencion de infecciones por virus de la inmunodeficiencia humana (vih-1)o para tratar el sida ao el arc.Info
- Publication number
- CL2007000362A1 CL2007000362A1 CL2007000362A CL2007000362A CL2007000362A1 CL 2007000362 A1 CL2007000362 A1 CL 2007000362A1 CL 2007000362 A CL2007000362 A CL 2007000362A CL 2007000362 A CL2007000362 A CL 2007000362A CL 2007000362 A1 CL2007000362 A1 CL 2007000362A1
- Authority
- CL
- Chile
- Prior art keywords
- ccr5
- pyrrole
- hiv
- treatment
- pharmaceutical composition
- Prior art date
Links
- 208000030507 AIDS Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- QFCMBRXRVQRSSF-UHFFFAOYSA-N 1,2,3,3a,4,5,6,6a-octahydropyrrolo[3,4-c]pyrrole Chemical class C1NCC2CNCC21 QFCMBRXRVQRSSF-UHFFFAOYSA-N 0.000 title 1
- 229940122444 Chemokine receptor antagonist Drugs 0.000 title 1
- 241000725303 Human immunodeficiency virus Species 0.000 title 1
- 239000002559 chemokine receptor antagonist Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- YKPJEYXZEBLYCI-UHFFFAOYSA-N pyrrolo[3,4-c]pyrrole Chemical class C1=NC=C2C=NC=C21 YKPJEYXZEBLYCI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Compuestos derivados de pirrolo[3,4-c]pirrol sustituidos; composición farmacéutica; y uso en el tratamiento de una infección del VIH o Sida.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77394206P | 2006-02-15 | 2006-02-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007000362A1 true CL2007000362A1 (es) | 2008-01-11 |
Family
ID=38157829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2007000362A CL2007000362A1 (es) | 2006-02-15 | 2007-02-12 | Compuestos derivados de octahidropirrolo {3,4-c}pirrol sustituidos,antagonistas de los receptores ccr5 de quimioquinas ccr5;composicion farmaceutica;y su uso en el tratamiento o prevencion de infecciones por virus de la inmunodeficiencia humana (vih-1)o para tratar el sida ao el arc. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070191335A1 (es) |
| EP (1) | EP1987036A1 (es) |
| JP (1) | JP2009526803A (es) |
| KR (1) | KR20080102387A (es) |
| CN (1) | CN101384596A (es) |
| AR (1) | AR059571A1 (es) |
| AU (1) | AU2007216543A1 (es) |
| BR (1) | BRPI0710474A2 (es) |
| CA (1) | CA2641389A1 (es) |
| CL (1) | CL2007000362A1 (es) |
| IL (1) | IL193107A0 (es) |
| NO (1) | NO20083585L (es) |
| RU (1) | RU2008136756A (es) |
| TW (1) | TW200801010A (es) |
| WO (1) | WO2007093520A1 (es) |
| ZA (1) | ZA200806756B (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1987035A1 (en) * | 2006-02-15 | 2008-11-05 | F.Hoffmann-La Roche Ag | Heterocyclic antiviral compounds |
| CN101516884A (zh) | 2006-09-18 | 2009-08-26 | 弗·哈夫曼-拉罗切有限公司 | 八氢吡咯并[3,4-c]吡咯衍生物和它们作为抗病毒药的用途 |
| US8754107B2 (en) * | 2006-11-17 | 2014-06-17 | Abbvie Inc. | Aminopyrrolidines as chemokine receptor antagonists |
| US8464207B2 (en) * | 2007-10-12 | 2013-06-11 | Novell Intellectual Property Holdings, Inc. | System and method for tracking software changes |
| DE102010025663A1 (de) * | 2010-06-30 | 2012-01-05 | Karl-Heinz Glüsenkamp | Neue beta-Aminoaldehyd-Derivate, Verfahren zu ihrer Herstellung und ihre chemische Verwendung als reaktive Intermediate |
| EP2780334A1 (en) | 2011-11-14 | 2014-09-24 | Basf Se | Substituted 1,2,5-oxadiazole compounds and their use as herbicides |
| UA116348C2 (uk) | 2012-04-27 | 2018-03-12 | Басф Се | Заміщені n-(тетразол-5-іл)- та n-(триазол-5-іл)арилкарбоксамідні сполуки та їх застосування як гербіцидів |
| IN2014MN02211A (es) | 2012-04-27 | 2015-07-10 | Basf Se | |
| CN102718695B (zh) * | 2012-06-25 | 2014-04-02 | 华东师范大学 | 一种氮杂双环[3.3.0]辛烷衍生物的合成方法 |
| AR092211A1 (es) * | 2012-09-24 | 2015-04-08 | Merck Patent Ges Mit Beschränkter Haftung | Derivados de hidropirrolopirrol |
| WO2014184058A1 (en) | 2013-05-15 | 2014-11-20 | Basf Se | Substituted 1,2,5-oxadiazole compounds and their use as herbicides |
| US20160108008A1 (en) | 2013-05-15 | 2016-04-21 | Basf Se | Substituted N-(Tetrazol-5-yl)- and N-(Triazol-5-yl)arylcarboxamide Compounds and Their Use as Herbicides |
| BR112015029979A2 (pt) | 2013-07-18 | 2017-07-25 | Basf Se | composto n-(1,2,4-triazol-3-il)arilcarboxamidas, composição, utilização de um composto e método para o controle da vegetação |
| WO2015052173A1 (en) | 2013-10-10 | 2015-04-16 | Basf Se | Tetrazole and triazole compounds and their use as herbicides |
| WO2015052178A1 (en) | 2013-10-10 | 2015-04-16 | Basf Se | 1,2,5-oxadiazole compounds and their use as herbicides |
| WO2015052153A1 (en) | 2013-10-10 | 2015-04-16 | Basf Se | Substituted n-(tetrazol-5-yl)- and n-(triazol-5-yl)arylcarboxamide compounds and their use as herbicides |
| EP2907807A1 (en) | 2014-02-18 | 2015-08-19 | Basf Se | Benzamide compounds and their use as herbicides |
| CN108473444A (zh) | 2015-12-17 | 2018-08-31 | 巴斯夫欧洲公司 | 苯甲酰胺化合物及其作为除草剂的用途 |
| CA3030381A1 (en) | 2016-07-14 | 2018-01-18 | Pfizer Inc. | Pyrimidine carboxamides as inhibitors of vanin-1 enzyme |
| US20200157086A1 (en) | 2017-05-30 | 2020-05-21 | Basf Se | Benzamide compounds and their use as herbicides |
| WO2018219936A1 (en) | 2017-05-30 | 2018-12-06 | Basf Se | Benzamide compounds and their use as herbicides ii |
| AR112112A1 (es) | 2017-06-20 | 2019-09-18 | Basf Se | Compuestos de benzamida y su uso como herbicidas |
| WO2019016385A1 (en) | 2017-07-21 | 2019-01-24 | Basf Se | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES |
| WO2019122345A1 (en) | 2017-12-22 | 2019-06-27 | Basf Se | Benzamide compounds and their use as herbicides |
| WO2019162309A1 (en) | 2018-02-21 | 2019-08-29 | Basf Se | Benzamide compounds and their use as herbicides |
| WO2019162308A1 (en) | 2018-02-21 | 2019-08-29 | Basf Se | Benzamide compounds and their use as herbicides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1761542T3 (pl) * | 2004-06-09 | 2008-06-30 | Hoffmann La Roche | Pochodne oktahydropirolo[3,4-c]pirolu i ich zastosowanie jako środków przeciwwirusowych |
-
2007
- 2007-02-06 CN CNA2007800051374A patent/CN101384596A/zh active Pending
- 2007-02-06 WO PCT/EP2007/051099 patent/WO2007093520A1/en not_active Ceased
- 2007-02-06 RU RU2008136756/04A patent/RU2008136756A/ru not_active Application Discontinuation
- 2007-02-06 JP JP2008554728A patent/JP2009526803A/ja active Pending
- 2007-02-06 CA CA002641389A patent/CA2641389A1/en not_active Abandoned
- 2007-02-06 KR KR1020087022382A patent/KR20080102387A/ko not_active Withdrawn
- 2007-02-06 EP EP07704382A patent/EP1987036A1/en not_active Withdrawn
- 2007-02-06 BR BRPI0710474-0A patent/BRPI0710474A2/pt not_active IP Right Cessation
- 2007-02-06 AU AU2007216543A patent/AU2007216543A1/en not_active Abandoned
- 2007-02-12 TW TW096105067A patent/TW200801010A/zh unknown
- 2007-02-12 CL CL2007000362A patent/CL2007000362A1/es unknown
- 2007-02-13 AR ARP070100591A patent/AR059571A1/es unknown
- 2007-02-15 US US11/706,807 patent/US20070191335A1/en not_active Abandoned
-
2008
- 2008-07-29 IL IL193107A patent/IL193107A0/en unknown
- 2008-08-05 ZA ZA200806756A patent/ZA200806756B/xx unknown
- 2008-08-19 NO NO20083585A patent/NO20083585L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007216543A1 (en) | 2007-08-23 |
| RU2008136756A (ru) | 2010-03-20 |
| JP2009526803A (ja) | 2009-07-23 |
| KR20080102387A (ko) | 2008-11-25 |
| BRPI0710474A2 (pt) | 2011-08-16 |
| AR059571A1 (es) | 2008-04-16 |
| IL193107A0 (en) | 2009-02-11 |
| WO2007093520A1 (en) | 2007-08-23 |
| CN101384596A (zh) | 2009-03-11 |
| US20070191335A1 (en) | 2007-08-16 |
| CA2641389A1 (en) | 2007-08-23 |
| TW200801010A (en) | 2008-01-01 |
| ZA200806756B (en) | 2009-11-25 |
| NO20083585L (no) | 2008-10-28 |
| EP1987036A1 (en) | 2008-11-05 |
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