TW200637836A - Cytotoxic agents comprising new taxanes - Google Patents
Cytotoxic agents comprising new taxanesInfo
- Publication number
- TW200637836A TW200637836A TW094142849A TW94142849A TW200637836A TW 200637836 A TW200637836 A TW 200637836A TW 094142849 A TW094142849 A TW 094142849A TW 94142849 A TW94142849 A TW 94142849A TW 200637836 A TW200637836 A TW 200637836A
- Authority
- TW
- Taiwan
- Prior art keywords
- cytotoxic agents
- taxanes
- therapeutic use
- novel cytotoxic
- new taxanes
- Prior art date
Links
- 229940123237 Taxane Drugs 0.000 title abstract 4
- 229940127089 cytotoxic agent Drugs 0.000 title abstract 4
- 239000002254 cytotoxic agent Substances 0.000 title abstract 4
- 231100000599 cytotoxic agent Toxicity 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 abstract 3
- 239000011230 binding agent Substances 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04292898A EP1669358A1 (en) | 2004-12-07 | 2004-12-07 | Cytotoxic agents comprising new taxanes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200637836A true TW200637836A (en) | 2006-11-01 |
Family
ID=34931583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW094142849A TW200637836A (en) | 2004-12-07 | 2005-12-06 | Cytotoxic agents comprising new taxanes |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7667054B2 (zh) |
| EP (2) | EP1669358A1 (zh) |
| JP (1) | JP2008523019A (zh) |
| KR (1) | KR20070085781A (zh) |
| CN (1) | CN101094857A (zh) |
| AR (1) | AR054100A1 (zh) |
| AU (1) | AU2005313444B2 (zh) |
| BR (1) | BRPI0518869A2 (zh) |
| CA (1) | CA2588587A1 (zh) |
| DO (1) | DOP2005000248A (zh) |
| EA (1) | EA012625B1 (zh) |
| IL (1) | IL183404A0 (zh) |
| MA (1) | MA29103B1 (zh) |
| MX (1) | MX2007006765A (zh) |
| MY (1) | MY144632A (zh) |
| NO (1) | NO20073033L (zh) |
| NZ (1) | NZ555406A (zh) |
| PE (2) | PE20110001A1 (zh) |
| TW (1) | TW200637836A (zh) |
| UY (1) | UY29249A1 (zh) |
| WO (1) | WO2006061258A2 (zh) |
| ZA (1) | ZA200704790B (zh) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1392359B2 (en) | 2001-05-11 | 2013-03-13 | Ludwig Institute for Cancer Research Ltd. | Specific binding proteins and uses thereof |
| US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
| ES2609094T3 (es) * | 2007-01-25 | 2017-04-18 | Dana-Farber Cancer Institute, Inc. | Uso de anticuerpos anti-EGFR en el tratamiento de enfermedades mediadas por un EGFR mutante |
| US20080207743A1 (en) * | 2007-02-28 | 2008-08-28 | Rodger Lamb | Biologically Active Taxane Analogs and Methods of Treatment |
| JP5618549B2 (ja) * | 2007-03-15 | 2014-11-05 | ルードヴィッヒ インスティテュート フォー キャンサーリサーチ リミテッド | Egfr抗体及びsrc阻害剤を用いる治療方法及び関連製剤 |
| MX2010001757A (es) | 2007-08-14 | 2010-09-14 | Ludwig Inst Cancer Res | Anticuerpo monoclonal 175 que activa el receptor egf y derivados y usos del mismo. |
| FR2947269B1 (fr) | 2009-06-29 | 2013-01-18 | Sanofi Aventis | Nouveaux composes anticancereux |
| FR2949469A1 (fr) | 2009-08-25 | 2011-03-04 | Sanofi Aventis | Derives anticancereux, leur preparation et leur application en therapeutique |
| US20110076232A1 (en) * | 2009-09-29 | 2011-03-31 | Ludwig Institute For Cancer Research | Specific binding proteins and uses thereof |
| UY32913A (es) | 2009-10-02 | 2011-04-29 | Sanofi Aventis | Nuevos maitansinoides y el uso de dichos maitansinoides para preparar conjugados con un anticuero |
| CN101851231A (zh) * | 2010-05-27 | 2010-10-06 | 东北林业大学 | 一种多西紫杉醇新衍生物的合成方法及其在制备抗肿瘤药物中的应用 |
| FR2963007B1 (fr) | 2010-07-26 | 2013-04-05 | Sanofi Aventis | Derives anticancereux, leur preparation et leur application therapeutique |
| ES2939836T3 (es) | 2012-07-12 | 2023-04-27 | Hangzhou Dac Biotech Co Ltd | Conjugados de moléculas de unión celular con agentes citotóxicos |
| ES2701076T3 (es) | 2012-11-24 | 2019-02-20 | Hangzhou Dac Biotech Co Ltd | Enlazadores hidrofílicos y sus usos para la conjugación de fármacos a las moléculas que se unen a las células |
| FI3122757T3 (fi) | 2014-02-28 | 2023-10-10 | Hangzhou Dac Biotech Co Ltd | Varautuneita linkkereitä ja niiden konjugointikäyttötapoja |
| CN104693156A (zh) * | 2014-10-22 | 2015-06-10 | 上海大学 | 9,10-二羟基-1-去氧紫杉醇类似物及其制备方法 |
| EP4678240A2 (en) | 2015-07-12 | 2026-01-14 | Hangzhou Dac Biotech Co., Ltd. | Bridge linkers for conjugation of cell-binding molecules |
| US9839687B2 (en) | 2015-07-15 | 2017-12-12 | Suzhou M-Conj Biotech Co., Ltd. | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule |
| MX2019005583A (es) | 2016-11-14 | 2019-10-21 | Hangzhou Dac Biotech Co Ltd | Vinculantes de conjugacion, conjugados de molecula de union a celulas que contienen los vinculantes, metodos de creacion y usos de dichos conjugados con los vinculantes. |
| KR20240095442A (ko) | 2021-11-03 | 2024-06-25 | 항저우 디에이씨 바이오테크 씨오, 엘티디 | 항체의 특이적 접합 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703247A (en) * | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
| FR2742751B1 (fr) * | 1995-12-22 | 1998-01-30 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| EP1242401B1 (en) * | 1999-11-24 | 2006-12-27 | Immunogen, Inc. | Cytotoxic agents comprising taxanes and their therapeutic use |
| US6596757B1 (en) * | 2002-05-14 | 2003-07-22 | Immunogen Inc. | Cytotoxic agents comprising polyethylene glycol-containing taxanes and their therapeutic use |
| JP2005539009A (ja) * | 2002-08-02 | 2005-12-22 | イミュノジェン・インコーポレーテッド | 新規の効力のあるタキサンを含む細胞毒性物質、および、それらの治療用途 |
-
2004
- 2004-12-07 EP EP04292898A patent/EP1669358A1/en not_active Withdrawn
-
2005
- 2005-11-29 PE PE2010000952A patent/PE20110001A1/es not_active Application Discontinuation
- 2005-11-29 PE PE2005001385A patent/PE20061060A1/es not_active Application Discontinuation
- 2005-12-01 MY MYPI20055612A patent/MY144632A/en unknown
- 2005-12-02 JP JP2007544849A patent/JP2008523019A/ja active Pending
- 2005-12-02 CA CA002588587A patent/CA2588587A1/en not_active Abandoned
- 2005-12-02 WO PCT/EP2005/014177 patent/WO2006061258A2/en not_active Ceased
- 2005-12-02 EP EP05843730A patent/EP1824858A2/en not_active Withdrawn
- 2005-12-02 EA EA200701251A patent/EA012625B1/ru not_active IP Right Cessation
- 2005-12-02 BR BRPI0518869-5A patent/BRPI0518869A2/pt not_active IP Right Cessation
- 2005-12-02 NZ NZ555406A patent/NZ555406A/en not_active IP Right Cessation
- 2005-12-02 MX MX2007006765A patent/MX2007006765A/es active IP Right Grant
- 2005-12-02 CN CNA200580045888XA patent/CN101094857A/zh active Pending
- 2005-12-02 KR KR1020077012679A patent/KR20070085781A/ko not_active Ceased
- 2005-12-02 AU AU2005313444A patent/AU2005313444B2/en not_active Expired - Fee Related
- 2005-12-02 ZA ZA200704790A patent/ZA200704790B/xx unknown
- 2005-12-05 AR ARP050105077A patent/AR054100A1/es unknown
- 2005-12-06 TW TW094142849A patent/TW200637836A/zh unknown
- 2005-12-06 US US11/295,294 patent/US7667054B2/en not_active Expired - Fee Related
- 2005-12-06 DO DO2005P000248A patent/DOP2005000248A/es unknown
- 2005-12-07 UY UY29249A patent/UY29249A1/es unknown
-
2007
- 2007-05-24 IL IL183404A patent/IL183404A0/en unknown
- 2007-06-14 NO NO20073033A patent/NO20073033L/no not_active Application Discontinuation
- 2007-06-18 MA MA30008A patent/MA29103B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2588587A1 (en) | 2006-06-15 |
| UY29249A1 (es) | 2006-06-30 |
| EP1669358A1 (en) | 2006-06-14 |
| DOP2005000248A (es) | 2007-02-15 |
| MA29103B1 (fr) | 2007-12-03 |
| EA012625B1 (ru) | 2009-10-30 |
| ZA200704790B (en) | 2008-08-27 |
| EP1824858A2 (en) | 2007-08-29 |
| BRPI0518869A2 (pt) | 2008-12-16 |
| KR20070085781A (ko) | 2007-08-27 |
| US20060178427A1 (en) | 2006-08-10 |
| PE20110001A1 (es) | 2011-01-21 |
| NO20073033L (no) | 2007-08-28 |
| IL183404A0 (en) | 2007-10-31 |
| WO2006061258A3 (en) | 2006-09-28 |
| NZ555406A (en) | 2011-02-25 |
| CN101094857A (zh) | 2007-12-26 |
| EA200701251A1 (ru) | 2007-12-28 |
| AU2005313444B2 (en) | 2011-11-10 |
| WO2006061258A2 (en) | 2006-06-15 |
| MY144632A (en) | 2011-10-14 |
| JP2008523019A (ja) | 2008-07-03 |
| MX2007006765A (es) | 2007-08-16 |
| PE20061060A1 (es) | 2006-11-14 |
| US7667054B2 (en) | 2010-02-23 |
| AR054100A1 (es) | 2007-06-06 |
| AU2005313444A1 (en) | 2006-06-15 |
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